Jonathan Taylor dazzled with a 67-yard rushing touchdown as the Indianapolis Colts ended the New England Patriots' winning streak with a 27-17 win on Saturday.

The Patriots, who had won seven games in a row, suffered their first road defeat of the season despite a gallant last-quarter fightback, closing within three points after trailing 20-0.

Taylor's 67-yard touchdown settled the contest with two minutes on the clock, after Patriots quarterback Mac Jones had twice found Hunter Henry for fourth-quarter TDs.

The Colts running back's touchdown marked a franchise record for rushing TDs in a season with 17. Taylor had 29 carries for 170 yards, while QB Carson Wentz completed five of only 12 attempts for 57 yards.

Earlier, Taylor escorted Nyheim Hines into the end-zone to put the Colts ahead, before Matthew Adams blocked Jake Bailey's punt, with EJ Speed swooping on the loose ball for a touchdown.

Darius Leonard intercepted Jones' second quarter pass as the Colts opened up a 17-0 lead. Jones would throw two touchdown passes but had two interceptions, completing 26 of 45 attempts for 299 yards.

The Patriots were left with too much in the final period, despite Henry's second TD with 2:21 left on the clock, and would rue penalties and mistakes.

The Colts improve to 8-6 and remain second in the AFC South, while the Patriots are 9-5.