The San Francisco 49ers won their first home game in more than a year after Jimmy Garoppolo helped fuel a 31-10 upset of the Super Bowl-chasing Los Angeles Rams.

All eyes were on debutants Odell Beckham Jr. and Von Miller after the high-flying Rams (7-3) acquired the star duo to boost their Super Bowl bid.

But the 49ers (4-5) spoiled the party – Garoppolo throwing two touchdown passes as San Francisco celebrated just their second home in the past two seasons, keeping their playoff hopes alive on Monday.

The 49ers, who have now won five straight games against the Rams – the longest active streak by either side, matching their 2008-10 run – had last emerged victorious on home soil in October 2020, also over the Rams.

Matthew Stafford (26-of-41 passing for 243 yards, a TD, two interceptions and two sacks) struggled as the Rams dropped back-to-back games, with the Los Angeles quarterback intercepted by Jimmie Ward on the opening two drives of the contest.

Ward's second interception led to a 27-yard touchdown return as he became the seventh player since 2000 with two interceptions – including a pick-six, in the opening quarter after Garoppolo (15-of-19 passing for 182 yards, two TDs and no interceptions) had led an 18-play, 93-yard TD drive less than a minute earlier.

Stafford has now thrown a pick-six in back-to-back games for the first time since his rookie season in 2009.

Leading 14-0 following the first quarter, the 49ers maintained that buffer as the teams traded touchdowns prior to half-time – Stafford throwing a 10-yard pass to Tyler Higbee before Deebo Samuel ran for an eight-yard score.

After Robbie Gould's 50-yard field goal stretched the lead in the third period, Samuel and Garoppolo combined for a 40-yard touchdown pass to put the 49ers out of reach early in the fourth.