Patrick Mahomes and Saquon Barkley were recognised as the respective AFC and NFC Offensive Player of the Week after flying starts to the new NFL season.
Mahomes led the Kansas City Chiefs to a dominant 44-21 Week 1 win at the Arizona Cardinals.
The 2018 MVP leads the league in passing touchdowns (five), passing yards (360) and quarterback rating (144.2) at this early stage.
Only Joe Burrow matched Mahomes' 22 passes for first downs, while he did not throw an interception and was not sacked, making him an obvious choice as the standout player in the AFC.
Minkah Fitzpatrick, who played a vital role in the Pittsburgh Steelers' wild win over Burrow's Cincinnati Bengals, is the AFC Defensive Player of the Year.
The Steelers safety caught a pick-six from Burrow's first pass of the game and later, crucially, blocked Evan McPherson's PAT to take the game to overtime.
Cade York was more accurate as time expired in the Cleveland Browns' dramatic victory over the Carolina Panthers, kicking the winning field goal to earn AFC Special Teams Player of the Week recognition.
In the NFC, New York Giants running back Barkley was the standout player on offense, stealing the show against a Tennessee Titans team featuring two-time rushing yards and rushing TDs leader Derrick Henry.
Barkley has the most rushing yards at this early stage with 164 and a score. His 68-yard run in the drive that culminated in his TD was the longest carry of the week.
The fifth-year superstar, who has been hampered by injuries since an outstanding rookie season, also caught a Daniel Jones pass for the decisive two-point conversion in a 21-20 Giants victory.
Also honoured in the NFC were debutant Seattle Seahawks linebacker Uchenna Nwosu and Philadelphia Eagles cornerback Zech McPhearson.
Nwosu sacked the Denver Broncos' former Seattle quarterback Russell Wilson and forced a fumble from Melvin Gordon at the one-yard line, while McPhearson fielded the Detroit Lions' attempted onside kick to set up a Boston Scott touchdown in an Eagles win.
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