For the first time in his illustrious career, an injury will prevent Los Angeles Rams seven-time Pro Bowl defensive tackle Aaron Donald from taking the field. 

Coach Sean McVay said on Wednesday that a high-ankle sprain suffered in the Rams' 26-10 loss to the Kansas City Chiefs in Week 12 will sideline Donald for Sunday’s game against the Seattle Seahawks. 

This will be the first game the 31-year-old Donald will miss since Week 17 of the 2017 season, when the Rams rested a number of starters ahead of the playoffs. The only other game he missed in his nine-year career was Week 1 of the same season because of a contract holdout. 

Despite missing those two games in 2017, he still won his first of three NFL Defensive Player of the Year Awards. 

Donald, who has five sacks, 10 tackles for a loss, 11 quarterback hits and a forced fumble in 11 games this season, is the latest Rams star to be saddled with an injury, joining quarterback Matthew Stafford (concussion protocol) and 2021 AP Offensive Player of the Year Cooper Kupp (high-ankle sprain). 

Unlike Kupp, whose high-ankle sprain required surgery, Donald won't need surgery, and is considered week to week, according to McVay. 

Although the injury isn't thought to be season-ending, there is a possibility the team ultimately decides to shut him down seeing as the Rams are essentially playing out the string. 

Last Sunday's loss was the fifth straight for Los Angeles, dropping the defending Super Bowl champions to 3-8 – alone in last place in the NFC West.