The San Francisco 49ers know all about playing on this stage, but Brock Purdy most definitely does not.

The Niners visit the Philadelphia Eagles in the NFC Championship Game on Sunday, their record 18th appearance in the conference championship in the Super Bowl era.

Yet they will do so with the youngest starting quarterback in a conference championship since Ben Roethlisberger in 2004.

And 22-year-old Purdy – 'Mr Irrelevant' in the 2022 draft – might have feared the prospect of facing a fierce Eagles defense this week as key team-mates Christian McCaffrey and Deebo Samuel managed injuries.

Losing either player would represent a huge blow to Purdy and the 49ers; losing both is unthinkable.

Fortunately, coach Kyle Shanahan has continued to speak with optimism of their chances of playing in Philadelphia, while McCaffrey added on Thursday there was "zero" chance of him missing this game.

On the other side of the field, the Eagles, who go into the game rated as narrow favourites, know a thing or two about playing without their leading stars.

QB Jalen Hurts missed two weeks towards the end of the season with a shoulder injury but was able to return in time to hit the ground running in the postseason.

The number one seeds in the NFC showed exactly why they are that by beating the New York Giants 38-7 in the Divisional round last week.

That tied the Eagles' biggest ever playoff win, which had come by the same scoreline in their previous NFC Championship Game appearance against the Minnesota Vikings. After that victory, they defeated the New England Patriots in Super Bowl LII.

Given the strength of the two defenses, this matchup should be a little closer – although perhaps not as close as the last time Hurts met Purdy.

Hurts' Oklahoma held off a comeback from Purdy's Iowa State for a 42-41 win in the 2019 college season.

That remains the only game in the past 10 seasons between Power 5 QBs in which both threw for 250 yards and three touchdowns while also rushing for 50 yards and a TD.