Philadelphia Eagles quarterback Carson Wentz will miss the remainder of the NFC wild-card clash against the Seattle Seahawks with a head injury.

Wentz, 27, left the field and was questionable to return after taking a blow to the back of his helmet from Seahawks defensive end Jadeveon Clowney in the first quarter of Sunday's NFL playoff game.

Veteran back-up Josh McCown replaced Wentz under center before the latter was officially ruled out by the Eagles after half-time in Philadelphia.

Wentz sat out Philadelphia's playoff run in 2017, his second season in the league, after tearing his anterior cruciate ligament (ACL) during the regular season.

In his absence, Nick Foles steered the franchise to their first Super Bowl triumph, as they beat the New England Patriots 41-33 in Minnesota.

Prior to the postseason showdown against the Seahawks, Wentz completed 388 passes for 4,039 yards and 27 touchdowns in 16 appearances.