Tom Brady was the hero in another historic performance as the Tampa Bay Buccaneers superstar inspired a 33-27 overtime win against the Buffalo Bills in the NFL.

Brady – who surpassed Drew Brees for the most pass completions in league history – became the first quarterback to throw 700 career touchdowns on Sunday and that milestone 58-yard TD settled the contest with the visiting Bills in OT.

Overtime was needed after reigning Super Bowl champions the Buccaneers (10-3) squandered a 24-3 half-time lead against the Bills (7-6).

Brady had thrown for a touchdown and ran for another after Leonard Fournette's 47-yard dash set the tone for the Buccaneers in the first half before the rallying Bills silenced the home crowd.

Josh Allen (36-of-54 passing for 308 yards, two touchdowns and an interception) was the instigator for the Bills with a pair of touchdown passes in the final period, after the quarterback's third-quarter run helped reduce the deficit.

Tyler Bass' 25-yard field goal 22 seconds from the end forced OT but Brady had the final say in another memorable moment in an incredible career – the seven-time Super Bowl champion and Breshad Perriman combining for a 58-yard score in the additional period.

Brady (31-of-46 passing for 363 yards and two TDs without an interception) maintained his dominant record against the Bills – the 44-year-old's 33 wins over Buffalo in 36 career starts are the most in NFL history against one team by a starting quarterback.

Niners also win in overtime

Overtime was needed to settle another game on Sunday, with the San Francisco 49ers prevailing 26-23 at the Cincinnati Bengals.

In a thrilling ending, Brandon Aiyuk hauled in the winning score on a 12-yard pass from Jimmy Garoppolo before staying in bounds and leapfrogging into the endzone.

The Bengals used a 14-0 final quarter to send the game into OT but the playoff-chasing 49ers managed to see off Cincinnati.