The Chicago Bears roughed up legendary quarterback Tom Brady and defeated the Tampa Bay Buccaneers 20-19 in NFL action on Thursday.

Chicago prevailed as Buccaneers QB Brady appeared to lose track of what down it was during a failed final drive in the Week 5 contest.

Brady remained on the field thinking the Buccaneers had one more play, having signalled to officials following a fourth incomplete down after Chicago's Cairo Santos kicked a 38-yard field goal with just over a minute remaining.

The six-time Super Bowl champion did not have a fourth down to work with after DeAndre Houston-Carson broke up Brady's fourth-down pass with 33 seconds left on the clock.

It meant Nick Foles' team got the better of Brady again, after the Philadelphia Eagles upstaged the New England Patriots in Super Bowl LII.

Brady was 25 of 41 for 253 yards and a touchdown as Tampa Bay's (3-2) three-game winning streak was snapped, while Chicago (4-1) bounced back from a loss to the Indianapolis Colts.

Bears quarterback Foles – the Super Bowl LII MVP for the Eagles – completed 30 of 42 passes for 243 yards and a touchdown in his second start since replacing Mitchell Trubisky.

The Buccaneers jumped out to a 13-0 lead in the second quarter – Mike Evans connecting with Brady for a two-yard pass in the opening period.

But the Bears quickly erased the deficit with just over a minute remaining in the first half as David Montgomery and Jimmy Graham scored touchdowns to put Chicago ahead.

Ryan Succop – who finished with four field goals – added three points in the third quarter to restore Tampa Bay's advantage and he converted a 25-yard attempt to give the Buccaneers a 19-17 lead with 4:49 remaining in the game.

But after Tampa Bay nose tackle Vita Vea was carted off the field, the Bears took over and held on in Chicago.