Andy Murray suffered one of the heaviest losses of his career in the second round of the Qatar Open, while Andrey Rublev escaped an early exit at the Open 13. 

Former world number one Murray went down 6-0 6-1 to last year's runner-up Roberto Bautista Agut in Doha on Wednesday. 

It was just the fourth occasion in which the three-time major champion has lost a match while winning only one game or fewer in his career – the last time being a defeat by the same scoreline to Roger Federer at the ATP Finals in 2014. 

Murray's fellow Briton Dan Evans also endured a second-round loss, going down 4-6 7-5 6-4 to Alejandro Davidovich Fokina – Bautista Agut's next opponent. 

Denis Shapovalov bounced back from his first-round loss to Jiri Lehecka in Rotterdam last week by dropping just eight points on serve as he claimed a 6-4 6-0 victory over Alex Molcan inside 52 minutes. 

Next up for the Canadian will be Arthur Rinderknech after the Frenchman came from a set down to defeat seventh seed Alexander Bublik 6-7 (5-7) 6-1 6-4. 

Nikoloz Basilashvili faced little trouble in overcoming Elias Ymer 6-4 7-5 and his reward is a quarter-final against Marton Fucsovics, who got the better of Kwon Soon-woo. 

Karen Khachanov and Marin Cilic will meet in the last eight after they respectively eliminated Emil Ruusuvuori and Botic van de Zandschulp. 

In Marseille, second seed Rublev was made to work hard for a place in the Open 13 quarter-finals by home hope Richard Gasquet. 

Gasquet went a break up in the third set and, after surrendering his advantage, stopped Rublev serving out the match to force a tie-break. 

However, the world number seven did not waste his next opportunity as he sealed a 4-6 6-4 7-6 (7-3) success. 

Aslan Karatsev also booked his place in the last eight, while there were wins for Frenchmen Benjamin Bonzi and Lucas Pouille too.