Michael Thomas and Marshon Lattimore headline a lengthy list of New Orleans Saints players ruled out of their Week 4 game against the Detroit Lions.

Wide receiver Thomas, who broke the NFL record for most catches in 2019 with 149 receptions, will miss a third successive game for a Saints team in need of kickstarting their season after back-to-back losses to the Las Vegas Raiders and Green Bay Packers.

Thomas has been troubled by an ankle injury and though he practiced on a limited basis this week, he will not suit up on Sunday.

Lattimore (hamstring) and fellow starting cornerback Janoris Jenkins (shoulder), have also been ruled out, along with tight end Jared Cook (groin), offensive lineman Andrus Peat (ankle) and defensive end Marcus Davenport (elbow/toe).

"I think they're a dangerous team, especially when they're healthy at receiver and having [Kenny] Golladay back in the lineup is significant for them," Saints head coach Sean Payton said of the Lions.

"[Lions quarterback Matthew Stafford] has got all the arm talent that you want at that position. He can fit it into tight windows. I think he's played well."