Denver Broncos wide receiver Tim Patrick is set to miss the entire 2022 season after being carted off the field with a right knee injury sustained during Tuesday's practice.

Patrick made a leaping grab on a pass from Russell Wilson, but upon landing and planting his foot to make a move, his knee buckled and he went down to the ground.

NFL Network Insider Ian Rapoport reported earlier on Tuesday that the Broncos were concerned he had suffered a significant injury.

It was later reported by Mike Klis of 9NEWS that the diagnosis was not good, according to sources, with an MRI apparently revealing it to be a torn ACL, meaning Patrick will miss the whole of next season.

Second-year running back Damarea Crockett was also getting an MRI after hobbling off the practice field and it is believed he also suffered a significant knee injury.

Losing Patrick will be a big blow for Denver as he was expected to see an increased role in first-year coach Nathaniel Hackett's offense with Wilson at quarterback.

The 28-year-old Patrick led the Broncos with five touchdown catches last season, while ranking third on the team in receiving yards (734) and receptions (53). It was his second straight season with 50+ catches, 700+ receiving yards and 5+ TD receptions.

Undrafted out of Utah, Patrick is entering his fifth season after signing a three-year, $34million contract extension with Denver last November.