The Indianapolis Colts have ruled running-back Jonathan Taylor out of contention for Thursday's clash against the Denver Broncos due to an ankle injury.

Taylor suffered a twisted ankle in Sunday's defeat to the Tennessee Titans but was hopeful that he would be able to feature in the opening game of Week 5.

"I definitely do plan to play, but if you can't go you can't go. That's why you have to get as much treatment as you can," he said on Tuesday.

However, the Colts announced on Wednesday that Taylor was among four players officially listed as out for the meeting in Denver, alongside safety Julian Blackmon (ankle), linebacker Shaquille Leonard (concussion/nose/back) and defensive end Tyquan Lewis.

Nyheim Hines is likely set to see increased usage on the ground in Taylor's absence, having largely been an aerial presence for the Colts this season – just 11 of his 124 yards in 2022 coming from rushing plays.

The Colts stand 1-2-1 for the season ahead of facing the Broncos, who they boast a 7-3 record against from their last 10 meetings.

Xabi Alonso has replaced Gerardo Seoane as Bayer Leverkusen's head coach.

Former Liverpool, Real Madrid and Bayern Munich midfielder Alonso coached Real Sociedad B between June 2019 and May 2022, having previously worked in Los Blancos's youth system.

The 40-year-old has now been handed his first head coach role at the top level on a two-year deal, with Leverkusen opting to part ways with Seaone after a dismal start to the season has left them sitting 17th in the Bundesliga.

"Gerardo Seoane has done a good job for Bayer 04 over the past year and a half, above all by qualifying for the Champions League," said sporting director Simon Rolfes. 

"Unfortunately, we have strayed from the road to success. From our point of view, the early elimination from the DFB-Pokal, but especially the fact that the current position in the Bundesliga is far below our expectations, made the change of coach imperative.

"In Xabi Alonso, we have signed a coach who, as a player, was an absolute world-class professional for many years, an intelligent strategist and extremely successful in three of the most demanding European leagues."

Alonso, who helped Spain win the 2010 World Cup, made 79 Bundesliga appearances for Bayern between 2014 and his 2017 retirement, winning three successive league titles under Pep Guardiola and Carlo Ancelotti.

"I know Leverkusen from my time in Germany as an excellent club," Alonso told his new team's official website. 

"Bayer 04 have always had great players, and I see a lot of quality in the current squad too.

"During discussions with the club, it quickly became clear that, despite the current difficult situation, ambitious goals are still being pursued in principle. I am very excited about this task and I am sure that we will live up to this claim."

Seaone's final game in charge was a 2-0 Champions League loss at Porto on Tuesday, Leverkusen's fourth defeat in their last five away games in the competition. 

Veteran wide receiver Cole Beasley has decided to retire from the NFL after 11 seasons.

His agents told NFL.com on Wednesday that Beasley was bringing an end to his career just two weeks after signing for the Tampa Bay Buccaneers.

After going unsigned as a free agent this offseason, Beasley joined the Bucs on September 21 with the team hit by a rash of injuries at receiver. 

The 33-year-old played in two games but only contributed 17 yards on four receptions.

"He is ready to be with his family after playing in 11 seasons, and it's time to be a full-time dad and husband," Beasley's agent Justin Turner said.

Beasley had been coming off two productive seasons with the Buffalo Bills. 

After recording career highs of 82 receptions and 967 receiving yards in 2020, the Texas native matched that catch total last season while posting 693 yards.

Considered undersized by most scouts, the 5-foot-8, 174-pound Beasley went undrafted despite producing two 1,000-yard seasons in college at SMU. 

He made Dallas' roster in 2012 and spent his first seven seasons with the Cowboys before signing a four-year, $29million contract with the Bills in 2019.

Beasley finishes his career with 554 receptions, 5,726 yards and 34 touchdowns in 151 regular-season games.

He also played in 11 postseason games during his time with Dallas and Buffalo.

Gareth Southgate believes England have grown stronger as a result of their poor form ahead of the World Cup, as he pledged to stand firm on his selections.

England suffered a humiliating relegation from the top tier of the Nations League last month, finishing their campaign with three points – and no wins – from six games.

The Three Lions begin their World Cup campaign against Iran on November 21, and their six-match winless run is their longest such sequence going into a major tournament.  

Southgate was jeered by England supporters in the aftermath of a 1-0 defeat to Italy on September 23 and has been criticised for standing by Manchester United's struggling defender Harry Maguire.

Speaking at Monday's Legends of Football event in aid of Nordoff Robbins Music, Southgate accepted criticism of his decisions, but maintained he must sometimes resist "popular appeal".

"I think everybody in the country can see we're trying to accomplish extraordinary things," he said. "To accomplish extraordinary things is incredibly difficult. 

"This is a job where every decision, every selection is questioned, debated, ridiculed. That's just by my postman, by the way!

"Column inches are full, airwaves are filled. As a manager, you're not going to get every decision right.

"But I have to be strong enough to withstand popular appeal for something and do what I really believe gives us the best chance to win. 

"If you can keep your head when all about you are losing theirs, and blaming it on you. If you can trust yourself, when all men doubt you, but make allowance for their doubting too. That doubting, that noise that surrounds us is because people care. They're passionate. 

"They just want to win, and I understand that. And if we don't win for six matches, then quite rightly, I have to accept that criticism. 

"That's what goes with our job. If nobody cared or commented, then it wouldn't be the great and incredible challenge that it is."

England failed to score an open-play goal in their first five Nations League games, before coming from 2-0 down to lead 3-2 in last week's thrilling draw with Germany, but Southgate believes the team's poor run could benefit them heading to Qatar.

"Milan was painful. I knew walking over to our fans that it wasn't going to end well. But I wasn't going to take a backward step," Southgate added.

"I've enjoyed the warmth and the adulation, so you've got to ride with the discomfort as well.

"Against Germany, I think we showed what we're capable of, good and bad. It showed there is character there. As a team, I think we'll be better for that challenging period we've just been through.

"You wouldn't choose to go into a World Cup with the run of results we've had, but I actually think we're stronger for that and the players have had to take some ownership. 

"Those moments, like coming back from to 2-0 down and hearing the roof lift off Wembley, are hard to describe."

With England reaching the World Cup semi-finals in 2018 and finishing as runners-up at Euro 2020, expectations surrounding the Three Lions have undoubtedly risen.

"In seven weeks' time, I get to lead my country to another World Cup. We have players I'm proud to lead, who give us everything," Southgate said.

"We want to bring people together, create memories and history. I've said before the last two tournaments: if we can make people proud, we'll have had an amazing time.

"I know that the bar of what might be deemed success is raised and getting higher for us. But as a team, we have to focus on performance, and the rest will fall into place.

Conor Benn expects his fight with Chris Eubank Jr to go ahead, despite being "prohibited" by the British Boxing Board of Control (BBBofC) after he failed a drug test.

Saturday's bout at London's O2 Arena was placed in jeopardy on Wednesday after it was revealed Benn had tested positive for female fertility drug clomifene.

The positive sample showed up in one of welterweight fighter Benn's recent tests, leading to the BBBofC to state that the fight was "not in the interests of boxing".

But Benn continued with his preparations as planned on Wednesday by taking part in an open workout session and feels the showdown will go ahead as planned. 

"I've not committed any violations and I've not been suspended, so as far as I'm concerned the fight is still going ahead," he told Matchroom's YouTube channel.

"I've signed up to every voluntary anti-doping test under the sun. Throughout my whole career I'm tested and I've always come back negative. I've never had any issues before. 

"My team will find out why there has been an initial adverse finding, but as far as I'm concerned the fight is going ahead. I'm a clean athlete and we'll get to the bottom of this."

Matchroom, Benn's representatives, had earlier said his "B sample had yet to be tested, meaning there is no rule violation and he is not suspended".

Benn added that he has spoken to Eubank Jr personally and that both "want the fight to happen for the fans".

However, speaking at his own workout, Eubank Jr said: "There was no phone call [with Benn]. We haven't spoken. 

"No phone call. We haven't spoken since this has been announced, and it's a shame you know. But my promoters, his promoters, the BBBofC they are going to sort this out."

The Eubank-Benn rivalry goes back over 30 years, with the fighters' respective fathers – Chris Eubank Sr and Nigel Benn – having fought in 1990 and 1993.

Eubank Sr won the first fight, with the second finishing as a split draw.

The Federation Internationale de l'Automobile (FIA) has delayed its decision over potential Formula One budget cap breaches by Red Bull and Aston Martin until October 10.

F1's governing body, which had been expected to release its Certificates of Compliance for the 2021 season on Wednesday, has made a five-day postponement to its decision amid ongoing furore.

Red Bull, whose driver Max Verstappen won the Drivers' World Championship in a controversial finale last year, are one of two teams alleged by rivals to have breached the competition's fiscal limits.

Principal Christian Horner has reiterated confidence in his team and threatened his counterpart at Mercedes, Toto Wolff, with legal action over his claims.

But the wait to discover just whether Red Bull committed a breach will now last until next week.

"The FIA informs that the conclusion of the analysis of the 2021 financial submissions of the Formula One teams and the subsequent release of Certificates of Compliance to the Financial Regulations will not take place on Wednesday, 5 October," the organisation stated.

"The analysis of financial submissions is a long and complex process that is ongoing and will be concluded to enable the release of the Certificates on Monday, 10 October.

"The Financial Regulations were agreed unanimously by all Competitors, who have worked positively and collaboratively with the FIA Cost Cap Administration throughout this first year under the Financial Regulations.

"As previously communicated, there has been significant and unsubstantiated speculation and conjecture in relation to this matter, and the FIA reiterates that until it is finalised, no further information will be provided.

"The FIA also reiterates that any suggestion that FIA personnel have disclosed sensitive information is equally baseless."

Punishment is likely to follow if Red Bull are deemed to have committed a breach, though the extent of whether it would strip Verstappen of his maiden world title is unknown.

Mikel Arteta said Arsenal will not take participating in the Europa League for granted ahead of Thursday's tie with Bodo/Glimt, but acknowledges the Gunners have loftier ambitions.

Arsenal sit top of the Premier League table after a scintillating start to the season; only twice have they bettered this campaign's return of 21 points after eight games in the competition, earning 22 points in 2004-05 and 2007-08. 

Having missed out to Tottenham in a fierce battle for Champions League qualification last term, however, Arsenal are competing with Bodo/Glimt, PSV and FC Zurich in Group A of Europe's second-tier competition. 

While Arteta knows Champions League football must be the aim for his team, he said Arsenal will "make the most" of their continental campaign.

"Playing in Europe is always great. We know we would want to be playing yesterday or today, but that's the next step," he said on Wednesday. 

"This is the reality, and we have to make the most of it.

"It's a test for the squad, in terms of the numbers and the quality. If you make changes, how much you notice it, whether you can continue consistently playing at the top level.

"Everyone's going to have to do that after the World Cup, especially with the schedule.

"It's a competition that is really important for us, we know how important it is to be on top of the group and the home advantage, we have to use it."

Meanwhile, William Saliba and Bukayo Saka have both expressed confidence they will sign new contracts after emerging as key components in Arteta's side, and the Arsenal boss says the club is working on deals for the duo, as well as fresh terms for Gabriel Martinelli.

Arsenal have been forced to sell several stars after allowing them to run their contracts down in the past, but Arteta moved to quell fears of a repeat, adding: "Obviously we have to plan for the future, and we are all working on it.

"Edu is on top of it, and all the board. We will try to do things in the right way, being fair, and rewarding the players that – in our opinion – have a big future for the club.

"When we have something to announce, we will do it. Every player is different and what happened in the past, the people that were in charge had the right reasons.

"We will try to do the same thing and make sure the club is always protected, that the club is always in a good position to move forward, and the players are happy."

Arsenal saw their first scheduled home game of the Europa League campaign, against PSV, postponed following the death of Queen Elizabeth II last month, and will look to end a poor continental run at the Emirates Stadium on Thursday.

The Gunners have failed to win any of their last three home European matches (D2 L1), their worst such run since they went six without victory between October 2002 and September 2003.

Novak Djokovic breezed past Cristian Garin in the Astana Open, taking just 62 minutes to secure a 6-1 6-1 victory in his opening match of the ATP 500 event.

Having won his 89th tour-level title on Sunday in Tel Aviv without dropping a single set, fourth-seed Djokovic wasted no time in securing a win to set up a second-round clash against Botic van de Zandschulp.

Also in Kazakhstan, third seed Stefanos Tsitsipas made hard work of his second-round tie against Luca Nardi, requiring two tie breaks in a two-hour showdown in a 7-6 (7-2) 7-6 (7-3) victory to secure a spot in the last eight.

Andrey Rublev, Roberto Bautista Agut and Adrian Mannarino also sealed their places in the quarter-finals at the Astana Open on Wednesday, while Marin Cilic and Emil Ruusuvuori won their first-round matches.

Meanwhile, Taylor Fritz defeated James Duckworth 6-2 6-7 6-1 in the Japan Open, where there was also a victory for Denis Shapovalov against Steve Johnson.

In the doubles, top seeds Nick Kyrgios and Thanasi Kokkinakis overcame home duo Yoshihito Nishioka and Kaichi Uchida, with second seeds Matthew Ebden and Max Purcell also progressing past the round of 16 stage.

Australia captain Aaron Finch declared his side will continue "tinkering" until the start of the T20 World Cup after starring in a three-wicket win over West Indies on Wednesday.

The Windies set a total of 145-9 before reducing Australia to 58-5 within eight overs on the Gold Coast, but Finch (58) and Matthew Wade (39 not out) led the hosts' successful recovery.

Taking an unfamiliar role at number four in the batting order, Finch moved to within 27 runs of becoming the first Australia batsman to score 3,000 runs in T20I history.

The world champions have experimented with their line-up in recent outings, including when Cameron Green opened during last month's tour of India, and Finch expects that to continue. 

"Both teams were sloppy if they are honest with themselves," he said. "But it's good to get across the line.

"We knew that total would be a challenge on that wicket, we did really well early and they took wickets in the middle.

"It would have been nice to get us over the line, I was trying to target the boundary but mishit one. I didn't like getting the first one in the head, but I really enjoy batting in the middle order. 

"It was just something different, we might change it up in the next match. We are going to keep tinkering with things until we get to the World Cup."

Australia will begin their defence of the World Cup against New Zealand on October 22 at the Sydney Cricket Ground.

Blake Bortles, the former number three overall pick, has revealed he has "quietly" retired from the NFL.

Bortles was selected by the Jacksonville Jaguars in the 2014 draft, becoming the first quarterback taken that year.

Despite largely not living up to his draft stock, Bortles helped the Jags, who had a famed defense in the 2017 season, to reach the AFC Championship Game where they narrowly lost to Tom Brady and the New England Patriots.

Bortles signed a three-year, $54million deal to remain with the Jags beyond his rookie contract but was released a year later after a poor 2018 season.

With his starting days behind him, the 30-year-old has since spent time in backup roles with the Los Angeles Rams, Denver Broncos, New Orleans Saints and Green Bay Packers.

But when asked if he was still in shape to sign for an NFL team during the 2022 season, he told the Pardon My Take podcast he had decided to call time on his career.

"I quietly... I didn't tell anybody, I retired," he said, per ESPN.

"I guess you guys are kind of the first to hear it publicly."

Chris Eubank Jr is unlikely to face Conor Benn as planned after the latter returned a positive test for the banned substance clomifene.

The bout was initially placed in jeopardy after welterweight fighter Benn tested positive for clomifene following a drugs test by the Voluntary Anti-Doping Association.

This was confirmed in a joint statement from Wasserman Boxing and Matchroom on Wednesday, though it was suggested the fight would still go ahead as scheduled.

However, the British Boxing Board of Control (BBBofC) subsequently confirmed the bout would not take place.

A BBBofC statement read: "On the evening of 4th October 2022, the Board of the British Boxing Board of Control Limited resolved that the contest between Chris Eubank Jr. and Conor Benn scheduled to take place on 8th October 2022 is prohibited as it is not in the interests of Boxing.

"That was communicated to the Boxers and Promoters involved on the morning of 5th October 2022."

Matchroom, Benn's representatives, had earlier said: "The B Sample had yet to be tested, meaning there is no rule violation. He is not suspended, and he remains free to fight. Mr Benn has passed all doping control tests conducted by the UK Anti-Doping Agency (UKAD)."

Eddie Hearn has since confirmed lawyers are in discussions with the BBBofC to try and ensure that the fight can take place.

A sold-out crowd had been expected to be in attendance for the event at the O2 Arena in London. 

The Eubank-Benn rivalry goes back over 30 years, with the fighters' respective fathers – Chris Eubank Sr and Nigel Benn – having fought in 1990 and 1993.

Eubank Sr won the first fight, with the second finishing as a split draw.

Sadio Mane has backed Karim Benzema to win this year's Ballon d'Or, stating Real Madrid's talisman "easily deserves" football's greatest individual accolade.

Benzema had an outstanding 2021-22 season, helping Madrid win LaLiga and the Champions League, with Los Blancos defeating Mane's Liverpool in the final.

Since the start of last season, Benzema has scored 48 goals and provided 16 assists in all competitions for Madrid. In the same time, only Kylian Mbappe and Robert Lewandowski (both 50) have netted more times.

The France striker also overtook Raul as Madrid's second-highest goalscorer, behind only Cristiano Ronaldo.

Now at Bayern Munich after leaving Liverpool, Mane has also been shortlisted for the Ballon d'Or.

He played a key role in Senegal winning the Africa Cup of Nations, while also propelling Liverpool to EFL Cup and FA Cup triumphs, though the Reds fell just short in Europe and in the Premier League.

After scoring one and setting up another in Bayern’s 5-0 rout of Viktoria Plzen in the Champions League on Tuesday, Mane was asked who he believes should scoop the prize.

"[Benzema's] had a great, great season with Real Madrid, he's won the Champions League... I think he easily deserves it, so I'm happy for him," Mane told reporters.

"I know I won the Africa Cup of Nations, it was a relief for me and for the whole country, and I'm really happy to have won my first AFCON with my country. But I think it's Karim who deserves it, and I honestly believe that."

Madrid legend, Jorge Valdano spoke to MARCA radio on the matter. 

He said: "There is no other name for the Ballon d'Or after an extraordinary season. [Benzema] played football of exceptional quality and he has added goals and leadership.

"He who is intelligent evolves in all aspects and he is the best example."

The 2022 Ballon d'Or ceremony will take place on October 17 in Paris. 

Liverpool centre-back Virgil van Dijk has leapt to the defence of team-mate Trent Alexander-Arnold amid recent criticism of the right-back's performances.

Alexander-Arnold has been the subject of plenty of scrutiny following his poor defensive performances in the Premier League and Champions League. 

The defender's mistakes in Liverpool's 3-3 draw with Brighton and Hove Albion on Saturday, in particular, drew heavy criticism from fans and pundits. 

The 23-year-old also failed to feature in either of England's two Nations League games last week, with Gareth Southgate making it clear Alexander-Arnold is not his first-choice right-back.

But van Dijk, speaking after Liverpool's 2-0 win against Rangers on Tuesday in which Alexander-Arnold opened the scoring with a stunning free-kick, said: "We know the quality he has and he showed it again today.

"He has been showing it over the last couple of years; he has developed as one of the best right-backs in the country."

Netherlands international Van Dijk also questioned the culture surrounding player welfare and media scrutiny in English football.

He said: "I've been in the UK now for eight, nine years and everyone here is very good to praise a player very high up to the sky and let them fall as hard as they can.

"That's what we, as players, have to deal with. Everyone is talking about how we should accept it.

"For him to just carry on working – not only him but other players as well – deal with it and show reaction today is what we need, all of us. I think it's important that we back him."

Liverpool's victory against Rangers leaves them second in Group A behind Napoli, who beat Jurgen Klopp's men 4-1 in the opening group game. 

Liverpool forward Darwin Nunez says he has had to learn to adapt to life in the Premier League after a difficult start, adding: "I needed to calm my nerves".

The Uruguay international was the flagship signing of the Reds' transfer window, and netted in his first two appearances for the club, in a blaze of early potential.

But a red card for an altercation with Crystal Palace's Joachim Andersen shortly afterwards handed him a three-match ban that has left him struggling to acclimatise since.

Nunez arguably delivered his best performance since the opening weeks in Tuesday's 2-0 home win over Rangers in the Champions League, and now feels he is making steps forward once more.

"The truth is that it was a little difficult to adapt, but I believe that, as training and games go by, I will adapt little by little," he told TNT Sports Brasil.

"[After the red card] was a very tough time. I was suspended for three games, I know I made a big mistake, and now I'm aware that it won’t happen again.

"I have to calm my nerves during the games, talk less. We all make mistakes and I know it will serve as a learning experience.

"The important thing is to leave my mark on the team, someone who can always contribute by playing well and, if I don’t score, I have to be calm."

Difficulties with the language barrier have seen Nunez lean heavily on Jurgen Klopp's assistant Pep Lijnders to bridge the gap, but the German has reassured his star of his support.

"I don’t know English and he doesn’t know Spanish," Nunez said about Klopp.

"But the relationship with the coach is that he supports me, gives me confidence and I have to repay that on the field."

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