Deebo Samuel's season is in jeopardy after being carted off the field while his San Francisco 49ers led 21-0 in the first quarter of Sunday's game against the Tampa Bay Buccaneers.

Samuel, who was named First Team All-Pro last season, had already run for one of the 49ers' three touchdowns against the Buccaneers, but his fourth carry of the half resulted in a fumble as his knee got trapped and twisted under a mass of bodies.

He could not get back to his feet, requiring a medical cart to drive him back to the locker room, and there was no update before half-time.

Samuel entered the game with the second-most receiving yards on the team this season (569) and the fourth-most rushing yards (207), contributing five total touchdowns.

His absence thrusts Brandon Aiyuk to the top of the depth chart, however it remains to be seen if the 49ers will use him in the hybrid fashion of Samuel's unique role.

The 49ers reached the end of the first half with a 28-0 lead, with rookie quarterback Brocky Purdy throwing two touchdowns and rushing for one in the first start of his career.

Last week, the 49ers lost quarterback Jimmy Garoppolo to a near season-ending foot injury, with Trey Lance already sidelined with an ankle injury.

Having helped the San Francisco 49ers past the Miami Dolphins after stepping in for an injured Jimmy Garoppolo, rookie quarterback Brock Purdy faces the considerable challenge of beating Tom Brady in his first start.

With Garoppolo described as having a "way outside chance" of returning for the playoffs after breaking his foot, the 8-4 Niners' Super Bowl hopes rest in part on the shoulders of a seventh-round pick, who was taken with the final selection of the 2022 draft.

The historical omens for a San Francisco victory in Purdy's first start are very good.

The Buccaneers have a 3-12 (.250) all-time record on the road against the 49ers. Among those with at least five all-time road games versus the Niners, no team has a worse record there than Tampa Bay. 

San Francisco's prospects of improving their already extremely impressive home record against Brady, playing on the road against the Niners for only the second time his glittering career, hinge not only on Purdy, but also a stacked cast of offensive weapons and the NFL's best defense.

Arguably the leading light among those weapons is a player they only acquired in October.

Running back Christian McCaffrey made his first start for the Niners following his trade from the Carolina Panthers in a Week 8 win over the Los Angeles Rams.

Since that first start, McCaffrey has 67 rushes for 269 yards and 31 catches for 258 yards.

He is one of two NFL players over that span with 60+ rushes and 30+ receptions (Rhamondre Stevenson being the other).

McCaffrey will likely continue to see a significant number of touches as the primary safety net for Purdy, who will also have significant support from a defense that forced four turnovers against one of the NFL's most explosive offenses in the win over Miami.

The 49ers prevailed 33-17 in that Week 13 clash. They have won five straight games while holding opponents to 17 or fewer points in each contest. It is the fourth such streak in team history, and the first since a six-game streak in the 1992 season.

With Tampa Bay averaging just 18.1 points per game, the 49ers should be confident of limiting Brady and Co.

Even if they do so, they may still need Purdy to ensure the game is not close in the fourth quarter, Brady having led the Bucs back from a 13-point deficit in the final period against the New Orleans Saints on Monday.

Brady has thrown nine of his 16 touchdowns (56.3 per cent) in the fourth quarter this season. Among 27 quarterbacks with at least 10 passing touchdowns this season, Brady is the only one with at least half of his touchdowns coming in the final frame.

The San Francisco 49ers looked destined to contend for a Super Bowl because of their astute move to invest in a quarterback insurance policy for Trey Lance.

Now with Jimmy Garoppolo, whom they kept around after attempting to trade away, likely also on the shelf for the rest of the season with a broken foot, the NFL world is left wondering whether one of the best rosters in the league can still go deep in the postseason with rookie seventh-round pick Brock Purdy at quarterback.

The early signs are promising, with Purdy stepping in for Garoppolo against the Miami Dolphins in Week 13 and producing a composed display in a 33-17 win that pushed the Niners' record to 8-4.

An enforced switch from Garoppolo to Purdy, the last pick in this year's draft, is an obvious downgrade, but how does it impact the 49ers' hopes of reaching the playoffs and Super Bowl?

Stats Perform can answer that question by looking at its rest-of-season (ROS) projection.

To generate the ROS predictions, every future game is projected to give a predicted win percentage for each team across its remaining games. The projections are calculated by looking at each team's quarterback and performance in terms of yards added in expected passing situations as well as team values for pass protection/pass rush, skill position players/coverage defenders and run blocking/run defense.

The projected win percentages are then aggregated to produce the forecasted standings, which suggest all is not lost for the 49ers.

Still Purdy Good

Purdy was poised, decisive and accurate after replacing Garoppolo, fostering hope he can help keep the 49ers in the Super Bowl hunt despite his inexperience at the highest level.

The ROS projection does not see the Niners winning the Super Bowl, giving San Francisco less than a one per cent chance to lift the Lombardi Trophy with Purdy under center.

However, the 49ers are still given an average win total of 10.5, putting them as the third seed as NFC West champions. With the division rival Seattle Seahawks projected to win 9.76 and end the season as the sixth seed, it would set up a mouthwatering Wild Card matchup.

The 49ers have done most of the hard work in their playoff pursuit and have a dominant defense that ranks first in EVE (our Efficiency Versus Expected metric).

As such, the Niners are still likely to make the playoffs, with ROS giving them a 95 per cent shot. What happens after that is up in the air with Purdy at the helm.

Chiefs Still Reign

The Kansas City Chiefs' loss to the Cincinnati Bengals in Week 13 dropped them out of the No. 1 seed in the AFC, with the Buffalo Bills once again in control of the conference.

ROS, though, expects the Chiefs to reassume the top spot by the end of the season.

The Chiefs are given a projected average win total of 12.8, the highest in the AFC and ahead of the Bills' 12.4.

On the NFC side, ROS does not project any slip-ups from the 11-1 Philadelphia Eagles, who are predicted to win 15.1 games and finish well clear of the Dallas Cowboys in the NFC East. The Eagles also have an NFL-best 35 per cent chance of winning the Super Bowl, with the Chiefs second at 18.8 per cent. 

If this projection is accurate, Dallas would face the prospect of playing the NFC South champion Tampa Bay Buccaneers on the road in the Wild Card round despite a 12-win campaign.

A dangerous Wild Card

ROS still appears to lack belief in the defending AFC champion Cincinnati Bengals despite a third successive win over the Chiefs.

Cincinnati are predicted to finish second in the AFC North behind the Baltimore Ravens with a projected average win total of 10.42. The margin is razor-thin, though, with the Ravens' total at 10.43.

The Bengals have just a 2.4 per cent chance to win the Super Bowl, according to the projection.

Yet with Joe Burrow and the Cincinnati offense catching fire in recent weeks, the Bengals loom as an extremely dangerous potential Wild Card team and the projected addition of the Miami Dolphins and New York Jets to the playoffs would make for one of the most fascinating AFC postseasons in recent memory.

By contrast, the recent tie between the New York Giants and Washington Commanders is unlikely to strike fear into the heart of any NFC contenders. They will renew acquaintances in Week 15, and it is the former who is projected to ultimately win out in their battle for the seventh seed and seal a Wild Card clash with the Minnesota Vikings.

The Giants have an average projected win total of 8.3 compared to 8.2 for the Commanders as the projection suggests a losing record will be good enough for at least one team to reach the postseason.

Only five weeks remain in the NFL regular season and places in the playoffs are still up for grabs heading into Week 14.

Come Monday, the Philadelphia Eagles, Kansas City Chiefs and Minnesota Vikings could all have booked their spot in the postseason should things go their way, while others could officially see their hopes ended.

Crucial meetings are set to take place between a number of playoff contenders, including divisional rivals the Eagles and the New York Giants.

Elsewhere, the in-form San Francisco 49ers host Tom Brady and the Tampa Bay Buccaneers, while the New York Jets face a Vonte Miller-less Bills in Buffalo.

Stats Perform has delved into the numbers for those matchups along with some of Sunday's other big games.

New York Jets (7-5) @ Buffalo Bills (9-3)

In Week 9, the Jets ended a four-game losing streak against the Bills to win 20-17, but Buffalo stand 7-3 in their last 10 meetings at home, winning each of the last two by double-digit margins.

In the defeat to the Vikings last week, Mike White had 369 passing yards and zero touchdowns; becoming the first Jets quarterback to throw for at least 350 yards without a touchdown pass.

Meanwhile, the Bills have been strong at home this season with just one defeat in Buffalo – coming in overtime to the Vikings in Week 10. They have averaged 33.4 points per game at home this season, outscoring their opponents by an average of 16.8 points.

An intriguing second half is on the cards, with the Bills holding a +48 points differential this season, the third-best ratio in the NFL, while the Jets rank fourth with a +44 differential.

Philadelphia Eagles (11-1) @ New York Giants (7-4-1)

Despite two consecutive wins against the Eagles at home, the Giants stand at 6-13 against the Eagles since 2003.

Standing 5-0 on the road this season, the Eagles are looking to tie a team record for consecutive road wins to start a season, set in 2001. Eight of the last 10 NFL teams to finish unbeaten on the road have gone on to reach the Super Bowl.

Jalen Hurts has thrown 20 touchdowns this season and has rushed for nine more, throwing just three interceptions, with no NFL quarterback ever finishing a campaign with 20+ passing TDs, 8+ rushing TDs and five or fewer interceptions.

This season, the Giants are the only NFL team not to allow a single offensive touchdown of at least 35 yards. Since 1940, the only year the Giants did not give up a single such touchdown was in 1994.

Tampa Bay Buccaneers (6-6) @ San Francisco 49ers (8-4)

Of teams to have played at least five games on the road against the 49ers, none have a worse record than the Buccaneers, who have won just three of 15 clashes in San Francisco (3-12).

The 49ers are on a strong run, having won five straight games while holding opponents to 17 or fewer points – the fourth such streak in franchise history and the first since a six-game stint in the 1992 season.

A comeback victory for the Buccaneers against New Orleans last week saw Tampa Bay overturn a 13-point deficit in the fourth quarter. Prior to that, the Buccaneers had lost their previous 62 such games, stretching back to the 2010 season.

Tom Brady has thrown 56.3 per cent of his touchdown passes this season in the fourth quarter (nine of 16). Among the 27 quarterbacks to have at least 10 passing TDs this season, he is the only one to have at least half of his coming in the final frame.

Miami Dolphins (8-4) @ Los Angeles Chargers (6-6)

The Dolphins stand 12-4 against the Chargers since 1995 but saw a five-game winning streak halted by a 33-17 loss on the road against the 49ers, where they had a season-low 33 rushing yards from eight carries – the fewest attempts in a game in Dolphins history.

Tyreek Hill remains a significant threat, tallying 146 yards in Week 13 to reach six 100-yard receiving games this season – the second-best total in a single season, behind only Mark Duper with eight in 1993.

Meanwhile, the Chargers lost to the Raiders last week despite leading 13-10 at half-time. That was their fourth loss this season in games where they have led at the interval, the second most in the NFL behind the Denver Broncos.

The two teams are second and fifth respectively in the NFL in terms of highest percentage of plays from passing attempts, but the Dolphins are first in pass yards per attempt (8.51), while the Chargers are 28th (6.52).

Elsewhere…

The Houston Texans travel to face the Dallas Cowboys, with the last two meetings between the teams going to overtime. There have been three instances of teams playing three consecutive games with overtime, most recently the Pittsburgh Steelers and the Atlanta Falcons from 2002-2010.

The Tennessee Titans host the Jacksonville Jaguars boasting a 9-1 record going back to 2017, the fifth-best record by any team against a division opponent in that span.

The Cleveland Browns head to Cincinnati on a five-game win streak against the Bengals, their best run against any opponent since rejoining the NFL in 1999.

The Minnesota Vikings are 10-2 this season despite being outgained by an average of 62.8 yards per game and head to Detroit to face the Lions, with the last four meetings all decided by four points or fewer.

Kyle Shanahan is not counting on seeing Jimmy Garoppolo back on the field for the San Francisco 49ers this season.

Quarterback Garoppolo broke his foot in the first quarter of Sunday's 33-17 win over the Miami Dolphins and head coach Shanahan confirmed a report from Tuesday that he did not suffer a Lisfranc injury that would require surgery.

Without the need for surgery and without any ligament damage, the timeline to recover from a fractured foot is in the seven-to-eight week range.

It was then being reported that he could be able to return for a Divisional Round game or the NFC Championship game, should the 49ers make it that far.

While his foot may be healed by the middle of January, Shanahan said he is not going to be ready to get back on the field from such an injury. 

'"There's that way outside chance late in the playoffs or something like that,'' Shanahan said on Wednesday. 

"'But it's just an outside chance. I'm not really real optimistic about that. But they didn't rule it out.

"'I know it's a serious injury that will likely keep him out for the year. It's really good news that there's no ligament damage or anything so he'll be fine once the broken bone heals.''

There is also the fact to consider if the 49ers are still alive in the second or third week of the playoffs, that Garoppolo’s replacement, Brock Purdy, is more than likely playing well enough.

After Garoppolo was injured against the Dolphins, Purdy capped his first drive with a three-yard touchdown pass to Kyle Juszczyk to put the 49ers ahead.

He threw another three-yard TD pass to Christian McCaffrey, and finished the day 25 of 37 for 210 yards with two touchdowns and an interception against a defense that attempted to unsettle him with blitzes.

Purdy, who was the last pick of this year's draft, had just attempted nine passes in his career prior to facing the Dolphins, and now gets a full week of preparation in practice with San Francisco's deep group of playmakers led by McCaffrey, Deebo Samuel, George Kittle and Brandon Aiyuk.

''We're trying not to make a drastic change,'' Shanahan said. ''They have a similar skill set. We got a lot of confidence in Brock. We've seen him in practice. That's why we were confident enough. 

"He hasn't played a ton football, so there is some unknown out there. But we know he's got the ability to do it. We know he's got the mentality to do it.''

San Francisco 49ers quarterback Jimmy Garoppolo could be in line to return for the postseason after a report suggested he would not require surgery on his broken left foot.

Garoppolo stayed down after being sacked by both Jaelan Phillips and Jerome Baker during the 49ers' 33-17 win against the Miami Dolphins on Sunday.

It was subsequently said he had broken bones in his foot which would likely require surgery, giving rise to fears his season was over.

49ers head coach Kyle Shanahan described the blow of losing his starting quarterback as "crushing", but his fears may yet be allayed, according to a report from ESPN's Adam Schefter.

The report claims Garoppolo avoided a Lisfranc injury and will not require surgery, potentially opening the door to his return to the field within seven to eight weeks.

If Garoppolo was to return within seven weeks, he could feature in any potential NFC Divisional Round game for San Francisco, while the NFC Championship game takes place one week later.

Super Bowl LVII, meanwhile, will take place another two weeks down the line, potentially giving Garoppolo the chance to win his third Super Bowl title.

On Monday, Shanahan indicated Garoppolo's injury may not be as bad as first feared, but was unwilling to speculate until he could give an official diagnosis.

"They're still trying to work through it," Shanahan said. "Some specialists have to finalise it, so we don't want to give you guys any false information. 

"They're discussing all those things, but we're feeling like it's starting to get better than that, so we'll see when we get the official information."

With any potential return for Garoppolo some time away, the 49ers will rely on Brock Purdy – the final pick in this year's draft – to fill the void following an encouraging display against the Dolphins.

On Monday, Shanahan refuted suggestions the 49ers could not compete for honours with Purdy in a starting role, saying: "He's decisive. He started for years [at Iowa State] at a high level. 

"You gotta have some balls to play quarterback in this league, and he does. We think we'll have a chance with him."

Kyle Shanahan believes the San Francisco 49ers will still "have a chance" with quarterback Brock Purdy after he was thrust into the starting role following a season-ending injury to Jimmy Garoppolo.

Garoppolo suffered a broken foot on the 49ers' first drive of their thrilling 33-17 win over the Miami Dolphins on Sunday, which maintained San Francisco's one-game lead atop the NFC West at 8-4.

Purdy was the final pick in the draft this year, earning him the tag 'Mr Irrelevant', but he is now the focus of San Francisco's season after an encouraging performance in relief of Garoppolo.

The former Iowa State quarterback completed 25 of his 37 passes for 210 yards, two touchdowns and an interception, the Niners outscoring the Dolphins 30-10 after Garoppolo left the game as San Francisco's top-ranked defense rattled Tua Tagovailoa and the NFL's most explosive offense.

Now the 49ers, a team who had Super Bowl aspirations with Garoppolo under center after he took over from injured 2021 third overall pick Trey Lance, must try to achieve their goals with Purdy under center.

While most may believe their hopes are now over, Shanahan is not giving up.

"What impressed me about Brock in [training] camp," Shanahan said, "is he was always willing to let it rip.

"He's decisive. He started for years [at Iowa State] at a high level. You gotta have some balls to play quarterback in this league, and he does. We think we'll have a chance with him."

Purdy will this week prepare for his first start, which will come against the man regarded as the greatest of all time, Tom Brady, and the Tampa Bay Buccaneers.

"Pretty cool," Purdy told King when asked about going against Brady. "The GOAT. He's been playing football longer than I've been alive."

But Purdy knows he will not have to do it alone, as he enters arguably the best offensive ecosystem in the NFL with Shanahan calling the plays for an attack stacked with weapons, and he also has the assistance of a defense that forced three turnovers from Tagovailoa as the 49ers beat a team led by former offensive coordinator Mike McDaniel.

"I know the question is, can I step in and continue this ride of what our team has done?" added Purdy.

"It's not just a one-man show or anything like that. What Jimmy did for this team was amazing in terms of getting it rolling and getting us on a streak to win.

"The challenge for me is like, man, can I step up in that position and continue to feed those guys? Get them the ball. Make the right checks in the run game. Allow the defense to play great and play with them. That's the challenge for me and that's how I look at it and I'm excited for it."

Miami Dolphins quarterback Tua Tagovailoa downplayed the severity of an ankle injury that forced him out late in Sunday's 33-17 loss to the San Francisco 49ers.

Tagovailoa, who completed 18 of 33 passes for 295 yards and two touchdowns with three turnovers, did not partake in the Dolphins' final drive and was listed as questionable to return.

That came after being listed on the injury report during the week with an ankle injury although he was able to fully participate in team practices.

"As good as I can be coming off a game," Tagovailoa told reporters after Sunday's defeat. "We'll assess some things but as good as I can be."

Tagovailoa's two interceptions came on successive passes in the third quarter. The third-year quarterback had given up three turnovers all season coming into Week 13.

The result leaves the Dolphins with an 8-4 record, with the Buffalo Bills on top of the AFC East with a 9-3 record fueled by a three-game win streak.

The Dolphins' own five-game win streak was ended by the 49ers and Tagovailoa lamented his performance.

"It sucks," he said. "It sucks that we didn't come out and do what we wanted to do as a team.

"Obviously, it starts with me - turnovers, with third-down communication errors. In that retrospect, it's hard to win a game when you're not on your P's and Q's and you're not dialed in.

"A lot of that has to do with understanding what we're trying to accomplish and what we're trying to do. It was definitely a poor performance from my part in that aspect of the game."

San Francisco 49ers head coach Kyle Shanahan called it "crushing" to lose starting quarterback Jimmy Garoppolo for the rest of the season after he broke his foot in Sunday's 33-17 win against the Miami Dolphins.

Garoppolo's injury came on the 49ers' eighth offensive play of the game, when he was sacked by both Jaelan Phillips and Jerome Baker to end their first drive. He stayed down, and ended up being carted off the field and promptly ruled out.

After the game it was revealed he had sustained broken bones in his foot, requiring season-ending surgery.

Starting the campaign as the third-string quarterback, Brock Purdy came in and threw two touchdown passes, managing the game efficiently before the 49ers' defense snagged a fumble-return touchdown to pull away.

Shanahan said it hurts to lose Garoppolo, but gave plenty of respect to Purdy for the performance.

"Just hearing it, it was pretty crushing," he told reporters. "We know what Jimmy has been through, how hard he's worked at this. He'll be out. He'll need surgery, broke a few things in there.

"Brock came in and made some big plays. We've got to clean some stuff up, obviously, but just throwing him in there in the heat of battle like that, [with] how much [all-out pressure] that team did, too, which you guys can see.

"We were having to change a lot of stuff on the fly, so putting a lot of pressure on [Purdy] in that way. I thought he did a hell of a job doing it. Protected the ball well, didn't have any turnovers and made some big plays too that I thought weren't there always."

The 49ers ruled out any possibility for Week 1 starter Trey Lance returning in time for a playoff run, meaning it will be Purdy the rest of the way, and he will make his first career start next week when Tom Brady and the Tampa Bay Buccaneers come to town.

"It’s gonna be pretty cool," Purdy said. "[Brady] has been playing football longer than I’ve been alive."

In fact, Brady played his final college game at Michigan four days after 22-year-old Purdy was born.

Defensive captain Fred Warner showed no signs of panic after he heard the news of Purdy's rise to the top of the depth chart, saying all his repetitions against this incredible 49ers defense in practice should have him ready.

"He's played against the best defense in the league for the past 13 weeks," he said. "He'll be fine."

The Cincinnati Bengals had strong contributions from all facets of their offense to defeat the Kansas City Chiefs 27-24 on Sunday.

In a rematch from last season's AFC Championship game – where the Bengals beat the Chiefs to advance to the Super Bowl – quarterback Joe Burrow was at his sharpest.

The 25-year-old former top overall draft pick completed 25 of his 31 passes, including touchdown passes to Tee Higgins in the second quarter and Chris Evans in the last, with Evans' score putting the Bengals up for good.

In his return from a five-game injury absence, last year's Offensive Rookie of the Year Ja'Marr Chase picked up right where he left off as Burrow's top option, catching seven passes for 97 yards, but backup running back Samaje Perine was even more influential.

Perine was used heavily in the fourth quarter as the Bengals looked to claw their way back from a deficit, with three of his six catches coming on their go-ahead touchdown drive, finishing with 49 yards through the air and another 106 on the ground from 21 carries.

It was not the best game from Chiefs quarterback and MVP favourite Patrick Mahomes, with 223 yards and one touchdown, as the Bengals committed to dropping eight defenders into coverage all game, forcing the Chiefs to accept small gains instead of their usual chunk-plays.

With the win, the Bengals are now 8-4, joining the Baltimore Ravens in a tie for the AFC North lead, while the Chiefs are three games clear atop the AFC West at 9-3.

Purdy party keeps the 49ers rolling

Brock Purdy was able to deliver a big 33-17 win for the San Francisco 49ers against the Miami Dolphins, but it came at a cost.

Purdy, the very last pick in this year's NFL Draft, was called upon when starting quarterback Jimmy Garoppolo was carted off and ruled out during their first drive of the game. Garoppolo has been diagnosed with a broken foot, with the team saying afterwards that it will end his season.

Almost a lock for the playoffs now at 8-4 with arguably the best defense in the league, the 49ers will need Purdy to get up to speed in a hurry if they still have dreams of a Super Bowl run, and he was solid against the Dolphins, completing 25 of his 37 passes for 210 yards, two touchdowns and one interception.

San Francisco 49ers starting quarterback Jimmy Garoppolo was carted off the field and ruled out of Sunday's game against the Miami Dolphins after only eight plays.

Garoppolo was sacked by Dolphins duo Jaelan Phillips and Jerome Baker on the 49ers' first drive, staying down and eventually needing the cart to carry him back down the tunnel.

He was swiftly ruled out of the remainder of the contest due to the foot injury he sustained, with rookie Brock Purdy brought in as the 49ers' new signal-caller. Purdy was the very last pick in this year's NFL Draft, earning him the title of 'Mr Irrelevant'.

Nevertheless, Purdy closed the first half in style, delivering short-range touchdown passes to Christian McCaffrey and Kyle Juszczyk to head into the break with the 49ers leading 17-10.

At 7-4 while boasting arguably the best defense in the NFL, the 49ers' Super Bowl dreams will take a massive hit if Garoppolo's injury keeps him on the sideline for an extended period.

With just six weeks left of the regular season schedule, the drama in the NFL continues to ramp up.

The playoff picture is wide open and Week 13 action presents clashes between a number of sides who each boast a winning record this season.

Victories this week would provide a considerable boost for those teams' hopes of continuing beyond the regular campaign.

A huge divisional rivalry between the Washington Commanders and New York Giants is the pick of the action, while there is also a rematch from last season's AFC Championship game with the Kansas City Chiefs seeking redemption against the Cincinnati Bengals.

Stats Perform has delved into the numbers for those matchups along with some of Sunday's other big games.

New York Jets (7-4) @ Minnesota Vikings (9-2)

The Jets head to Minnesota with an 8-3 record against the Vikings, though have lost the last two meetings – including a 37-17 loss in the last meeting in 2018, which marked the most ever points scored by the Vikings in this series.

Defensive strength has been key for the Jets this season, with last week's 31-10 victory over the Chicago Bears being the fourth time this year where they have held their opponents to 10 or fewer points – the last time they had such a sequence was five games in 2010, which was also their last season with a trip to the playoffs.

The Jets defense will be tested against the Vikings' aerial threat, however, with Justin Jefferson and Adam Thielen each catching touchdown passes in the Thanksgiving win over the New England Patriots – the ninth time each player has had a receiving TD in the same game, which marks the most of any NFL teammates since Jefferson's 2020 debut.

A win against the Jets would see head coach Kevin O'Connell join Jim Caldwell and Jim Harbaugh as the only men this century to earn 10 wins in 12 or fewer games to start their career as an NFL head coach.

Washington Commanders (7-5) @ New York Giants (7-4)

A series sweep for Washington last season was the franchise's first against the Giants since 2011, leaving the Commanders looking for their first win streak of at least three games against New York since a four-game streak that ended in 2000.

Four consecutive wins on the road have seen Washington hold their opponents to 54 points total in those contests, marking the first time they have won four straight road games while allowing fewer than 60 points since 2001.

The Giants head into the contest having lost their last five against divisional opponents, standing just 1-7 in that regard over the past two seasons. That makes them just one of two teams without multiple wins in divisional games over that span (also Denver Broncos, 1-8).

Saquon Barkley remains the biggest threat for the Giants and sits just eight rushing yards short of his third 1000-yard season, where he would join Tiki Barber (6), Rodney Hampton (5) and Joe Morris (3) as the only Giants with at least three such seasons for the team.

Tennessee Titans (7-4) @ Philadelphia Eagles (10-1)

Philadelphia host the Titans on the back of a six-game winning run against AFC opponents dating back to last season, matching the Eagles' longest such streak in franchise history.

Last time out against the Green Bay Packers, the Eagles scored a touchdown in four of their five trips to the red zone – with Philadelphia leading the NFL in touchdown efficiency in the red zone this season, scoring in 29 of 40 trips (72.5 per cent).

Tennessee, meanwhile, have rushed for fewer than 100 yards in each of their last three games, matching their longest streak since Mike Vrabel became head coach in 2018.

In the 20-16 loss to the Bengals last time out, Derrick Henry fumbled but was it was recovered. Of the 39 players with at least 200 offensive touches since the beginning of last season, Henry, Leonard Fournette and Christian McCaffrey are the only three to have not lost a fumble.

Kansas City Chiefs (9-2) @ Cincinnati Bengals (7-4)

Two meetings last season saw the Bengals win by three points in both contests, including in the AFC Championship game in Kansas City, with the Chiefs' last road win against the Bengals coming in 1984 – losing six straight since.

A 26-10 home victory against the Los Angeles Rams last week saw Travis Kelce catch his 12th touchdown pass of the season, with no other tight end having more than five this term. The largest all-time gap between a league leader and second place stands at six (Rob Gronkowski in 2011 and Antonio Gates in 2004).

The Bengals overcame the Titans 20-16 on the road last week, giving Cincinnati their first three-game winning streak of the season. Since 2018, they stand 3-34 when scoring 20 or fewer points in a game, but two of those wins have come against Tennessee.

Cincinnati have converted 78.1 per cent (25-for-32) of their third downs this season when needing fewer than four yards, the best mark in the league. However, they've also allowed opponents to convert such third downs at a 76.5 per cent rate (26-for-34), the worst record in the league.

Elsewhere…

The Miami Dolphins head to San Francisco with a 4-3 record on the road against the 49ers, the second-best such record by any team behind the Carolina Panthers (7-4).

The Los Angeles Rams host the Seattle Seahawks having won eight of the last 10 clashes between the two divisional rivals, with Seattle's last victory on the road in this matchup coming in Week 5, 2017.

An overtime victory over the Seahawks last week was the second in a row for the Las Vegas Raiders, having beaten the Denver Broncos in OT in Week 11. No NFL team has ever won three consecutive games in overtime going into the Raiders' latest battle with the Los Angeles Chargers.

The Dallas Cowboys host the Indianapolis Colts on the back of a four-game spell with at least 400 net yards, with only one longer streak in team history – running eight games in that regard in 2016.

No journey to the Super Bowl is ever linear. Ever since the Miami Dolphins achieved football perfection in 1972, every team that has climbed the mountain has had to experience some kind of bump in the road, and any team that harbours ambitions of adding their name to the list must show an ability to win in different ways and prevail when one side of the ball misfires.

The 2022 San Francisco 49ers have hit several bumps in the road. From a Week 1 loss to the Chicago Bears in a monsoon, to losing the anointed quarterback of the future, Trey Lance, to a season-ending ankle injury in Week 2 and suffering back-to-back losses to the Atlanta Falcons and the Kansas City Chiefs, the latter of which saw them ship 44 points, there have been plenty of points this season where belief in the 49ers as the Super Bowl contenders has been tested.

But San Francisco's response to the blowout Week 7 loss to the Chiefs has been emphatic and has reaffirmed the 49ers' status as a heavyweight in the NFC.

The 49ers have reeled off four successive victories to surge to 7-4 and, if the season ended today, would win the NFC West and enter the playoffs as an extremely dangerous third seed.

Two of those four wins have been blowouts, San Francisco marrying devastating offense from a group overflowing with playmakers following the October trade for Christian McCaffrey with tremendous defensive fortitude to destroy a pair of NFC West rivals in the Los Angeles Rams and Arizona Cardinals on the road.

Even with the level of star talent they have at their disposal, the 49ers' offense has not been consistent. A continuing theme of their recent dominance has been DeMeco Ryans' defense, which reached its 2022 zenith to this point on Sunday with a shutout 13-0 win over the New Orleans Saints.

It was a performance that served as an encapsulation of why Ryans is likely to be the premier head coaching candidate this offseason and one that should serve to raise the question of whether his defense is one that could be among the select few that carries its team to Super Bowl glory.

The numbers point heavily to the 49er defense being of that standard.

San Francisco's shutout was the Niners' first since they beat Washington 9-0 in the 2019 season, and it was the first suffered by the Saints since Week 17 of the 2001 season. The 49ers were the team to dole out the shutout on that occasion in a 38-0 win.

While it was a 20-year low point for the Saints on offense, for the 49ers it was a continuation of an eye-opening run of defensive obduracy. The Niners have now pitched four consecutive shutouts in the second half, also keeping the Rams, Los Angeles Chargers and Cardinals off the board in the final two quarters. Achieving the feat for four quarters against the Saints, they have now not conceded a point in over 94 minutes of game action.

The 49ers' refusal to let the Saints avoid drawing a blank was made more amazing by the fact New Orleans had six plays from inside San Francisco's five-yard line, and the season-long defensive numbers for the Niners paint the picture of the defiance shown by Ryans' group that could well come to define their season.

San Francisco's defense ranks first in points per game allowed, yards per game allowed, rush yards per game allowed, yards per rush allowed, first downs per game allowed and passing touchdowns allowed.

Simply put, this is a defense that can shut down anything an opposing offense does well, and it has multiple means by which it can do so.

The 49ers have the sixth-highest sack rate in the NFL at 7.9 per cent but have a blitz rate of 28.7 per cent that is below the league average of 30.8 per cent, those numbers speaking to San Francisco's long-established ability to get home by only sending four pass rushers from their exceptionally deep defensive line.

Nick Bosa, the star of that front, recorded the fourth-down sack that essentially ensured the Saints would not score in Week 12, taking his tally for the year to 11.5.

Bosa is the fifth player since 2000 to record at least one sack in nine of his first 10 games of a season, joining Hugh Douglas (2000), Everson Griffen (2017), Robert Mathis (2005) and Demarcus Ware (2008).

Yet the Niners have also made a habit of sending successful blitzes at the right time, with linebacker Fred Warner and safety Talanoa Hufanga – who each forced fumbles on Sunday – proving adept at generating pressure when rushing from the second level of the defense.

Hufanga's physicality jarred a fumble from Alvin Kamara at the one-yard line in the first of two fourth-quarter red zone stops against New Orleans, the former fifth-round pick emerging as a star in a secondary that has duplicity to frustrate teams with precise and disciplined zone coverage and facilitate blitzes by succeeding when it pivots to man coverage, with cornerback Charvarius Ward, the 49ers' headline free agency acquisition, excelling in both areas.

As with many defenses around the NFL, the 49ers rely heavily on two-high safety zone coverages; however, they have used Cover 1 man on 13.35 per cent of defensive snaps, well above the league average of 10.64 per cent. When using that coverage, they have given up 5.22 yards per play, over a yard fewer than the league average of 6.58.

In essence, the personnel Ryans has at his disposal allows him to easily switch between the staple of a four-man rush with zone coverage behind it and a more aggressive approach at any point and still have complete confidence his defense will deliver.

Though blitzes are not an overly common feature of the game plan, San Francisco's underpinning defensive philosophy is all about aggression, which is evident throughout when Ryans' players are on the field, their relentless pursuit of the football critical to the 49ers' incredible success against the run – opponents have gained only 3.1 yards per play on the ground versus San Francisco – and game-sealing turnovers such as Kamara's goal-line fumble.

That defensive violence ensured San Francisco did not follow the 49ers' offensive fireshow against the Cardinals in Mexico City with a letdown even as that attack sputtered in comparison to its efforts at Estadio Azteca.

Fast, physical, disciplined and diverse with the players at every level to consistently dominate, the 2022 49ers defense has all the ingredients of a championship unit and proved it can carry the load in ensuring San Francisco won in a very different way in Week 12 following the blowout of Week 11.

With Jimmy Garoppolo playing some of the best football of his career, after sticking around to back up Lance in a prescient move by both player and franchise, and blessed with a skill-position group that features McCaffrey, Deebo Samuel, Brandon Aiyuk and George Kittle, the hope will be the defense will not have to shoulder the burden on a regular basis. But this four-game stretch has proven unequivocally that it can do so, and that is an excellent insurance policy for the 49ers as they plot a path to a second Super Bowl appearance in four seasons.

San Francisco 49ers running back Elijah Mitchell will spend at least the next six weeks on the sidelines after suffering his second MCL sprain of the season in Sunday's win against the New Orleans Saints.

It is the same injury he suffered in Week 1, and in that instance he did not return until Week 10, proceeding to contribute in three consecutive wins before bad luck struck again.

A sixth-round pick in last year's NFL Draft, Mitchell burst onto the scene with 1,100 yards from scrimmage as a rookie, but following his injury to begin this season, the 49ers made the decision to invest further in the running back position.

Their trade for former Carolina Panthers superstar Christian McCaffrey insulates the 49ers from the crushing blow of this injury, as it will result in an increased workload for the two-time All-Pro.

Niners head coach Kyle Shanahan said he felt for the 24-year-old after the news of his impending stint on the sidelines.

"It wasn't the news we were looking for," he told reporters. "He's pretty disappointed. 

"Everyone knows how good Elijah has been, how hard he worked to get back from his last one, how good he's been playing since he came back, and to kind of be right back there, I know he was real down on it. 

"It's unfortunate for him. He's just had some real bad luck."

He added: "He knows what's ahead of him. He's just going to have about six weeks of frustration, but hopefully we can do our job here so when he comes back, we're still playing."

There are six weeks remaining in the regular season, and with a 7-4 record, the 49ers are a strong contender for a deep playoff run.

This Thursday marks Thanksgiving in the United States.

That means several things. Food, family and lots and lots of football, with the traditional three games on the schedule for the holiday.

With the Buffalo Bills, Dallas Cowboys and Minnesota Vikings all playing, there will be plenty of fantasy relevant players in action, meaning there's no time to waste in terms of getting a winning line-up set.

Thanksgiving is, as the name makes obvious, a time to say what you're grateful for, and Stats Perform hopes you will be appreciative of the fantasy help we're here to provide with our picks of four offensive players and a defense for Week 12.
 

Quarterback: Justin Herbert, Los Angeles Chargers @ Arizona Cardinals

The Chargers may not be feeling too grateful after having their heart broken again by Patrick Mahomes and the Kansas City Chiefs on Sunday.

But they must be appreciative of getting to face the Cardinals' defense in Week 12, especially with Herbert's top receiver, Keenan Allen, back in the fold.

The Cardinals have allowed 118 pass plays of 10 yards or more, the fourth-most in the NFL. Coming off a game in which he averaged 9.3 yards per attempt, Herbert is well-positioned to get the Chargers' playoff push back on track against opposition that should facilitate one of his best performances of the season.

Running Back: Jeff Wilson Jr, Miami Dolphins vs. Houston Texans

When Dolphins head coach Mike McDaniel sits down to eat his turkey on Thursday, he may express thanks for the trade with his former employers, the San Francisco 49ers, that landed Wilson's services for Miami.

Wilson has quickly established himself as the top runner in a Dolphins backfield that was not firing on all cylinders prior to his arrival.

He averaged seven yards per carry against the Cleveland Browns' dreadful run defense last time out and now gets to face a Houston defense that has allowed 57 runs of at least 10 yards, which is 12 more than anyone else in the league.

Wide Receiver: Amon-Ra St. Brown, Detroit Lions vs. Buffalo Bills

Detroit's leading receiver may not be happy to go against the Buffalo defense in Week 12, but Jameson Williams' debut is likely to bring a smile to his face.

Williams, Detroit's second first-round pick in 2022, is practising after recovering from a torn ACL he suffered in his final college game, and will give the Lions a tremendous deep threat who can stretch the field and open underneath areas for St. Brown to exploit.

In a game where the chances of the Lions falling behind and being forced to throw the ball consistently are high, that is a recipe for St. Brown racking up completions and yardage in the Thanksgiving opener.

Tight End: T.J. Hockenson, Minnesota Vikings vs. New England Patriots

There is likely to be gratitude in Vikings circles that they get the chance to quickly wash the stink off from their blowout loss to the Dallas Cowboys in Week 11.

Having been shellacked by the Cowboy defense, the Minnesota offense will face a different challenge in the form of the Patriots, who consistently drop eight players into coverage.

New England will almost certainly look to take Justin Jefferson away with double teams, meaning quarterback Kirk Cousins will likely have to frequently look to Hockenson over the middle of the field.

Targeted 28 times in three games since his arrival in a trade with Detroit, Hockenson appears primed for massive fantasy performance in the Thanksgiving nightcap, especially in points per reception leagues.

Defense/Special Teams: San Francisco 49ers vs. New Orleans Saints

The Saints' coaching staff may have a stressful Thanksgiving game planning for the 49ers, who appear to be rounding into form on both sides of the ball.

San Francisco's defense has not allowed a second-half point in any of the Niners' last three games and is giving up just 4.67 yards per play this season, the second-fewest in the NFL.

Facing a Saints offense that has committed the most giveaways (19) in the NFL, the San Francisco defense should dominate once more and deliver a crucial contribution for its fantasy owners.