The San Francisco 49ers have confirmed Brandon Aiyuk has torn the anterior cruciate and medial collateral ligaments in his right knee and will miss the rest of the season.

Star wide receiver Aiyuk was injured near the end of the second quarter as the 49ers lost a Super Bowl LVIII rematch against the Kansas City Chiefs, 28-18, on Sunday.

That result dropped them to 3-4 after an injury-plagued start to 2024, with running back Christian McAffrey another big-name absentee. 

Head coach Kyle Shanahan suggested after the game that Aiyuk's injury looked serious, and the team's worst fears were confirmed when he undertook additional tests on Monday.

"I talked with him last night, just calling him at his house," Shanahan said of Aiyuk. "He was hurting, just bummed out, exactly how you'd expect. 

"But he's a strong dude and spiritual guy and believes everything happens for a reason, so he'll be all right. 

"He was definitely a little down last night, and I was just telling him how bad I felt for him and just let him know we're all here for him through this."

Fellow wideout Deebo Samuel, meanwhile, was limited to four snaps against the Chiefs after feeling unwell and was subsequently checked into hospital with a form of pneumonia.

"I think it started acting up in the middle of the night Saturday night or early Sunday morning and then it just evolved as the day went on," Shanahan said of Samuel.

"Once we found out he had the fluid in his lungs after the game, then I believe they sent him over there."

There is no timeline for Samuel's return to action, with the Niners' next outing pitting them against their long-time rivals, the Dallas Cowboys, on Sunday.

Cleveland Browns coach Kevin Stefanski fears that quarterback Deshaun Watson suffered a season-ending Achilles injury during their 21-14 defeat to the Cincinnati Bengals.

Watson will go through tests to confirm a diagnosis for his injury, which he suffered on Sunday.

But Stefanski did not have a great outlook after the game.

"Obviously, it doesn't look good with the injury," he told ESPN.

"I'll give him a call here in a little but ... disappointed for him. Any of our guys that you lose, you're disappointed because you know much this means to them and how hard they work. It's tough."

Watson's injury was sustained during a non-contact play when his leg hyperextended and he fell to the ground.

It compounds a miserable start to the season for the Browns, who are bottom of the AFC North with a 1-6 record.

Fan frustration was noticeable, with many seeming to cheer Watson's injury after he had been booed during the pregame.

"We don't boo guys that are injured on the field, especially when the cart comes out," said defensive end Myles Garrett said after the game.

"We should be ashamed of ourselves as Browns and as fans to boo anyone and their downfall."

Stefanski was in agreement with Garrett.

"I don't think it's ever OK to cheer when someone's injured. I'm sure it's not every person in the building doing that, but that's disappointing," he said.

Meanwhile, it is feared San Francisco 49ers receiver Brandon Aiyuk suffered a torn ACL during their 28-18 defeat to the Kansas City Chiefs on Sunday.

"That's what it looks like, but we don't know for sure," coach Kyle Shanahan told ESPN. "Been wrong before. So, praying that we are [again]."

Further tests will confirm the exact issue and determine whether Aiyuk will miss the rest of the season.

With fitness problems mounting for the 49ers, Deebo Samuel was also announced to be suffering from illness before kick-off but was still expected to play.

He was withdrawn after four snaps with no catches or carries.

"Throat, stomach things, just real fatigued," Shanahan said, on Samuel. "Struggled to breathe, couldn't catch his breath ... he kept trying to fight through it, but once he was struggling with the breathing and everything, we had to shut him down."

Aiyuk's teammates, meanwhile, were vocal in their disappointment at potentially missing the wide receiver for the remainder of the season.

"It sucks," said tight end George Kittle. "I love Brandon Aiyuk, the energy that he brings, what he can do on the football field, routes, catching the ball. He's an incredible football player. You can't really replace, in my opinion, one of the best receivers in the NFL."

Quarterback Brock Purdy echoed Kittle's sentiments.

"What BA does for our offense and who he is and as a teammate and the brother of ours, man, it's sad," he said.

"Wish him nothing but the best and praying for him. So that's my guy. And when he goes down like that, obviously we have other guys that can step up and do their job really well ... we all just got to come together as a group collectively, the receiver unit and all of us."

San Francisco 49ers linebacker Fred Warner hailed the team for standing tall on the road after they held off a Seattle Seahawks fightback for a crucial 36-24 win.

The Niners were in dire need of a victory after blowing double-digit fourth-quarter leads in losses to the Los Angeles Rams and Arizona Cardinals in Weeks 3 and 5.

They made a strong start to Thursday's meeting between two NFC West rivals, assuming a 23-3 lead early in the third quarter, as Brock Purdy threw a 76-yard catch-and-run touchdown to Deebo Samuel and another score to George Kittle.

However, the defending NFC champions let Seattle back in and saw their lead trimmed to six points by the start of the fourth, with the Seahawks reeling off 14 straight points then getting the ball back via a Rasheem Green interception.

However, they held firm and another two touchdowns – a second Purdy-Kittle link-up and a six-yard Kyle Juszczyk rush – ensured they improved to 3-3, level with Seattle. 

Asked if doubts began to creep in as the Niners' lead shrunk, three-time All-Pro Warner said: "A thousand percent. 

"It sucks, but yes, it was something that felt familiar for sure. We could go one of two ways right there. 

"We could stand tall in a hostile environment and get the game that we got to get or we could settle for exactly how we've been playing the last couple losses."

The 49ers' season has seen them hampered by injuries to the likes of Christian McCaffrey, Dre Greenlaw and Javon Hargrave, and head coach Kyle Shanahan was handed another headache on Thursday as running back Jordan Mason was forced off with a shoulder issue.

Asked for an update on Mason's condition after the game, Shanahan said: "He thought he was going to be alright.

"He went back in, and it just hurt him too much, so he went out. We'll find out more tomorrow."

San Francisco's victory came at a crucial time as they are involved in the matchup of the season so far in Week 7, when they face the Kansas City Chiefs in a repeat of February's Super Bowl LVIII clash.

Offensive tackle Trent Williams said of that game: "It's not like we can get payback for losing in the Super Bowl. That ship has sailed. 

"Obviously, we know what type of team that is, one of the best teams in the league... All-Star quarterback, great coach. 

"We're going to take these three days off and regroup and try to put a complete game together."

Brock Purdy threw for 255 yards and three touchdowns, and the San Francisco 49ers never trailed in a 36-24 victory over the Seattle Seahawks on Thursday night.

Deebo Samuel had a 76-yard catch-and-run touchdown and finished with three catches for 102 yards for the defending NFC champions (3-3), who moved into a tie with Seattle (3-3) for first place in the NFC West after an uneven start to the season.

George Kittle added five receptions for 58 yards and two scores for the 49ers, who beat the Seahawks for a sixth straight time. Kyle Juszczyk added a late TD run for the 49ers, and he and Kittle both celebrated their scores by leaping into the stands to embrace their wives, who were sitting together in the first row.

Matthew Wright, who joined San Francisco earlier this week to replace injured kicker Jake Moody, had a trio of first-half-field goals from 25, 41 and 35 yards.

Geno Smith passed for 312 yards and a touchdown but was intercepted twice, and the Seahawks lost their third straight after a 3-0 start under new coach Mike Macdonald.

Brock Purdy threw for 255 yards and three touchdowns, and the San Francisco 49ers never trailed in a 36-24 victory over the Seattle Seahawks on Thursday night.

Deebo Samuel had a 76-yard catch-and-run touchdown and finished with three catches for 102 yards for the defending NFC champions (3-3), who moved into a tie with Seattle (3-3) for first place in the NFC West after an uneven start to the season.

George Kittle added five receptions for 58 yards and two scores for the 49ers, who beat the Seahawks for a sixth straight time. Kyle Juszczyk added a late TD run for the 49ers, and he and Kittle both celebrated their scores by leaping into the stands to embrace their wives, who were sitting together in the first row.

Matthew Wright, who joined San Francisco earlier this week to replace injured kicker Jake Moody, had a trio of first half-field goals from 25, 41 and 35 yards.

Geno Smith passed for 312 yards and a touchdown but was intercepted twice, and the Seahawks lost their third straight after a 3-0 start under new coach Mike Macdonald.

The San Francisco 49ers' selection woes show no signs of easing with defensive tackle Javon Hargrave suffering a potentially season-ending injury and Christian McCaffrey needing specialist treatment on an Achilles issue.

The 49ers have made a 1-2 start to the 2024 season after winning the NFC championship for the eighth time last campaign, with injuries hampering them early on.

McCaffrey, the NFL's reigning Offensive Player of the Year, was placed on injured reserve last week after missing the entirety of preseason with what was later diagnosed as Achilles tendonitis.

Wide receiver Deebo Samuel and tight end George Kittle also missed Sunday's 27-24 defeat to the Los Angeles Rams, during which Hargrave partially tore his right triceps.

That injury will require surgery and will likely bring his 2024 season to a premature end.

Head coach Kyle Shanahan said: "It's a big loss. I thought he had his best game. I thought he was a huge factor, really affected the quarterback in that game. 

"He's one of our better players. He was definitely going in the right direction and was going to have a big year."

McCaffrey, meanwhile, has flown to Germany to see a specialist regarding his Achilles issue.

He must miss four games after being placed on IR. Having missed two thus far, he cannot return until after the 49ers' October 6 meeting with the Arizona Cardinals at the earliest. 

Shanahan also revealed quarterback Brock Purdy had complained of back soreness after the Rams game and would be evaluated daily, though an MRI scan came back all-clear.

Brock Purdy insisted the San Francisco 49ers' stellar 2023 season "means nothing" after they went down 27-24 to their NFC West rivals, the Los Angeles Rams, on Sunday. 

The Rams trailed 21-7 late in the third quarter and 24-14 in the fourth before scoring 13 points to deal a depleted 49ers team a second defeat of the campaign. 

San Francisco were without three of their offensive stars, with Christian McCaffrey on injured reserve and both wide receiver Deebo Samuel and tight end George Kittle also missing out. 

But the Rams were also missing some of their key men, with their top two receivers, Cooper Kupp and Puka Nacua, sidelined due to injury.

After starting last season 5-0 on their way to the NFC Championship, San Francisco have failed to build on their Week 1 triumph against the New York Jets this year.

At 1-2, the Niners are well aware that there is plenty of the season left, but they also know missing opportunities like Sunday's may come back to haunt them.

"That's just part of the NFL and being a professional in a professional sport, everybody's really good," Purdy said. "Last year means absolutely nothing.

"And every time you show up on Sunday, you're going to get everybody's best shot. It's the NFL, and we all have to be real with that.

"We have to have the mindset of going and taking it every Sunday and nothing's ever going to be given to us."

The Niners still had the chance to win the encounter, with wide receiver Jauan Jennings delivering a career-best 11 catches for 175 yards and three touchdowns. 

In doing so, Jennings became the fourth player in franchise history to have 175 receiving yards and three scores in the same game.

Purdy, meanwhile, didn't miss a beat without his usual weapons, finishing 22-of-30 for 292 passing yards and three touchdowns with a 137.1 passer rating. 

However, Purdy didn't get much help from his targets, most notably Ronnie Bell, who dropped a catch in the final quarter to spurn a golden game-winning opportunity.

The loss made Purdy the third 49ers signal caller (alongside Joe Montana and Steve Young) to lose a game in which he completed at least 70% of his passes and threw for three or more touchdowns.

It also dropped the Niners below the .500 mark for the first time with Purdy as their starter, with head coach Kyle Shanahan left furious at the conclusion of proceedings. 

"You've got to take their hope away," Shanahan said.

"You give [Rams quarterback Matthew] Stafford too much hope [and] you put a ball in his hands at the end, it's not a situation you want to be in."

The San Francisco 49ers are considering placing star running back Christian McCaffrey on injured reserve as he continues to battle calf and Achilles issues.

McCaffrey missed the Niners' season-opening victory over the New York Jets on Monday, having struggled with soreness in his right calf and tendinitis in his Achilles. 

On Thursday, head coach Kyle Shanahan ruled McCaffrey out of the team's Week 2 trip to face the Minnesota Vikings on Sunday, and conversations are now taking place about placing him on the injured reserve list.

If they do so, he will have to sit out at least four more games, leaving San Francisco without one of their foremost offensive weapons for a significant period of the season.

"It's something we're considering now," Shanahan told reporters. "Yesterday was his worst day. 

"It's on and off, but with yesterday having the most pain. It's something we're going to be discussing together in the next 24 hours."

McCaffrey won the NFL's Offensive Player of the Year award for 2023 after helping San Francisco reach Super Bowl LVIII in Las Vegas, where they suffered a dramatic overtime defeat against the Kansas City Chiefs.

He led the NFL in rushing with 1,459 yards with 14 touchdowns in his first full season with the 49ers, having arrived in a blockbuster trade from the Carolina Panthers in 2022.

McCaffrey admitted his injury problems were causing him plenty of frustration earlier this week, telling reporters: "My mindset every week is that I'm going to play.

"There's been weeks when I'll go the full week, not even feeling good enough to do the walk-through, and then I wake up and the body's capable of a lot of cool things. 

"Mentally, I'm always prepared to play, and then I woke up and it was a group decision, a very tough one. 

"I hate not playing, but I look at it as a chess move and something that hopefully you can benefit from the rest of the season."

Aaron Rodgers says there are "no excuses" for the New York Jets after mistakes saw them fall to a 32-19 loss to the San Francisco 49ers in their NFL opener.

Rodgers, making his first appearance since rupturing his Achilles tendon in the Jets' first game of 2023, struggled for much of his return.

He was held to just 167 yards on 13-of-21 passes and had an interception that led to one of five field goals for San Francisco, though he did throw one touchdown pass to Allen Lazard in the third quarter. 

The 40-year-old was less than impressed with his first start in 20 months and is already looking for improvements.

"That's an excuse [none of the starters playing in pre-season]. I'm not going to use that," Rodgers said. "I don't think we should. We expect greatness when we step on the field.

"This is a tough opener for us, travel-wise and schedule-wise, but no excuses. We have to play better, and I have to play better, and we'll bounce back."

Rodgers became just the 22nd quarterback in the Super Bowl era (since 1966) to play after his 40th birthday, and despite the disappointing result, he was pleased to be back out on the field.

"It felt great," he added. "A lot of gratitude just to be back in pads. So many people helped me get to this spot.

"I'm really thankful for my surgeon, my loved ones, my friends, the staff and the training staff to help me get back. Obviously, I wanted to take a shot and feel the physicality of it.

"Once I threw a couple of balls and took a shot, it felt good."

The 49ers played without star running back Christian McCaffrey, who was ruled out shortly before kick-off due to a calf and Achilles injury.

Jordan Mason stepped up in his absence, playing a starring role for the Super Bowl runners-up as he finished with a career-high 28 carries for 147 yards and a touchdown.

"I thought he runs like he always does," coach Kyle Shanahan said.

"When you get him the ball, he breaks tackles, usually gets more than we block for. When we had the good lanes, he always hit them, and we got a bunch."

Brandon Aiyuk seems set to leave the San Francisco 49ers after he was granted permission to speak to other teams.

Contract talks between the 49ers and their top wide receiver have stalled in recent weeks.

The Pittsburgh Steelers, the New England Patriots and the Cleveland Browns have all been credited with an interest in Aiyuk, who had 1,342 receiving yards last season, a career-high.

And San Francisco coach Kyle Shanahan has now confirmed Aiyuk has been allowed to open talks with other teams.

He said: "You're always disappointed when you can’t keep hold of all your players and it’s not going exactly right.

"I don't like losing anybody, so that’s why I am hoping it does work out here. But right now, we don't have that solved.

"You want everybody out there. You truly understand the business side of our league and what these guys do and what they have to go through in these deals.

"Whether it’s a hold-in or a holdout, this stuff is pretty common and you've just got to be patient with it as a coach."

Asked about signing a replacement if Aiyuk were to leave, Shanahan added: "Brandon's a great player, so it's really hard to be better when you lose a great player.

San Francisco 49ers receiver Brandon Aiyuk is currently in a contract battle with the team, and Fred Warner believes it is a "good issue to have".

Aiyuk was in contract negotiations with the 49ers to extend his current deal but reportedly has not held talks with them since May.

Unable to reach a deal, the 26-year-old instead asked for a trade.

It is not the first time the 49ers have found themselves in lengthy contract disputes, going through the same process to resign Nick Bosa, Deebo Samuels and Warner himself.

The linebacker was unfazed by the controversies though, instead choosing to focus on the positives.

"When you're part of such a talented roster, I feel like this is something that goes on every season," Warner said via NBC Sports Bay Area.

"It's a good issue to have because, obviously, that means that your players are performing at such a high level that you have to have these kinds of conversations."

Aiyuk is under contract with San Francisco for 2024 in the option year of his rookie deal.

He impressed last season on their run to Super Bowl LVIII, earning second-team All-Pro honours and ranking seventh in the NFL with a career-high 1,342 receiving yards.

His average of 17.9 yards per catch ranked second in the league, while only the Miami Dolphins' Tyreek Hill bettered his 16 receptions of 25 or more yards.

Overall, since being picked in the 2020 draft, Aiyuk has 269 receptions for 3,931 yards, with 25 touchdown catches in 62 games.

As a key figure in the team, Aiyuk has been supported by his team-mates throughout the dispute, and Warner said he is ready to welcome him back when the saga is sorted.

"It's a part of the business, and so we all just let them handle that. And when he's back, he's back. We'll welcome him with open arms."

Christian McCaffrey has reset the running back market in the NFL.

McCaffrey agreed to a two-year, $38million extension with the San Francisco 49ers on Tuesday, making him the league's highest-paid running back.

The new deal keeps McCaffrey, who turns 28 on Friday, under contract for the next four years after he signed a four-year, $64million extension in 2020 following his third season with the Carolina Panthers.

The 49ers acquired McCaffrey from the Panthers via a trade during the 2022 season, and he won the AP Offensive Player of the Year award in his first full season in San Francisco in 2023 after leading the NFL in rushing with 1,459 yards with 14 touchdowns.

He added another 564 receiving yards and seven TD receptions to help the 49ers secure the top seed in the NFC.

In 27 games with the 49ers, he has 2,205 rushing yards and 20 touchdowns to go with 1,028 receiving yards and 11 receiving TDs.

Since his 2017 rookie season, he leads all players with 10,505 scrimmage yards, while his 81 scrimmage touchdowns trail only Derrick Henry's 88.

Known for his bruising running style, McCaffrey also leads all players with 72 runs of at least 10 yards over the last two seasons.

McCaffrey attended the first day of San Francisco's mandatory mini-camp on Tuesday after skipping voluntary work-outs over the last two weeks.

The Kansas City Chiefs have become back-to-back Super Bowl winners for the first time in 20 years with a 25-22 overtime win over the San Francisco 49ers in Las Vegas.

Needing a field goal to extend the game or a touchdown to win, Chiefs’ quarterback Patrick Mahomes orchestrated the match-winning drive to end the game with a touchdown pass to Mecole Hardman Jr.

The 49ers were leading by three in overtime after they opted for a field goal to go ahead 22-19, but were unable to get the decisive stop.

It was the second time in NFL history a Super Bowl went to overtime and the first post-season game decided under the league’s new overtime rules.

Mahomes finished with 333 throwing yards, two touchdowns and 66 running yards, while 49ers quarterback Brock Purdy threw for 255 yards with one touchdown.

The only points in the first quarter came through kicker Jake Moody, who made Super Bowl history with the longest made field goal at 55 yards.

Disaster struck 49ers’ linebacker Dre Greenlaw early in the second quarter when he went down with a suspected Achilles injury while running onto the field and was immediately ruled out of the game.

But not long after, a special trick-play led to the first touchdown of the game, with Purdy passing across field to wide-receiver Jauan Jennings before he threw a pass to Christian McCaffrey who ran through to the endzone untouched.

The 49ers restricted Travis Kelce to just one touch for one yard in the first half and sacked Mahomes twice, with the 49ers ahead 10-3 at halftime.

Alicia Keys, Lil John and Ludacris joined Usher during the half-time performance, while Taylor Swift was among celebrities including Blake Lively, Lady Gaga, Beyonce and Jay Z watching from the stands.

As play resumed, Chiefs kicker Harrison Butker broke Moody’s Super Bowl record with a 57-yard field goal before a fumble error gave the Chiefs a huge chance for their first touchdown.

Mahomes found wide-receiver Marquez Valdes-Scantling with a 16-yard touchdown pass to take the lead for the first time in the game late in the third quarter.

However the 49ers hit back – with Purdy finding Jennings this time to score his own touchdown – however the bonus point was blocked, giving the 49ers a three-point lead with 11 minutes left.

A field goal to Butker tied the game once again, before Moody struck back to give the 49ers the lead again with less than two minutes left.

However, Butker finished regulation time with a field goal with six seconds left to tie the game 19-19.

Nathan MacKinnon stayed hot and the Colorado Avalanche bounced back from a lacklustre loss to beat the San Jose Sharks 6-2 on Sunday.

MacKinnon tallied a season-best four points, recording two goals and two assists to extend his point streak to 15 games one night after the Avalanche fell behind 3-0 and 5-1 in a 6-2 loss to the Winnipeg Jets.

MacKinnon now has eight goals and 19 assists during his point streak, which ties the longest point streak of his career from the 2020-2021 season. He also has 38 points in his last 21 games and has at least one point in all 16 home games this season.

His 47 points on the season are second only to Tampa Bay's Nikita Kucherov, who has 52.

Mikko Rantanen, Ryan Johansen, Valeri Nichushkin and Miles Wood also had goals for Colorado, while Alexandar Georgiev turned aside 27 shots.

It marked the third win in four games for the Avalanche (19-10-2), who scored at least five goals in all of those victories.

The Sharks (9-19-3), meanwhile, lost their second in a row following a 3-0-1 stretch.

Tomas Hertl scored both of San Jose's goals, while MacKenzie Blackwood stopped 23 of 28 shots.

Boeser moves into NHL-lead for goals scored as Canucks top Blackhawks

The Vancouver Canucks didn't look quite awake for the start of their early afternoon game in Chicago.

They suddenly woke up in the second period and pulled out a 4-3 win over the Blackhawks.

After managing just one shot on goal in the first 10 minutes and five shots in the opening period, the Canucks found themselves trailing 2-1 on Nick Foligno's second goal of the game 35 seconds into the second period.

Vancouver then came alive, trying things up on Dakota Joshua's goal and took the lead 41 seconds later on Brock Boeser's score. Ilya Mikheyev also scored in the second period for the Canucks (21-9-2), who improved to 5-0-1 since a 6-5 loss to the New Jersey Devils on December 5.

Boeser's goal was his 10th in the last 11 games and 23rd of the season to move him into a tie with Toronto Maple Leafs superstar Auston Matthews for the most in the NHL.

Elias Pettersson also scored for the Canucks and Thatcher Demko made 25 saves to win his fourth consecutive start.

Petr Mrazek stopped 22 shots and rookie sensation Connor Bedard notched two assists to give him 14 on the season for the Blackhawks (9-20-1), who lost their fourth straight game and fell to 4-13-1 since November 12.

Eichel helps Golden Knights beat Senators

Jack Eichel scored 1:37 into the game and the Vegas Golden Knights went on to a 6-3 win over the Ottawa Senators.

Eichel's goal was his 14th of the season and extended his point streak to a franchise-record 10 games.

Eichel also added an assist, and Ivan Barbashev had a goal and an assist as well for the NHL-best Golden Knights (21-6-5), who bounced back from their first regulation loss since November 25.

Logan Thompson came off the bench to make 20 saves for Vegas after Adin Hill was forced out only 6:25 into the game.

The Golden Knights extended their win streak over the Senators to nine games and improved to 10-1-0 all-time against them.

Ottawa (11-15-0) lost its fourth in a row overall, allowing at least four goals in each of those defeats.

The San Francisco 49ers have two credible candidates to be named NFL MVP in Brock Purdy and Christian McCaffrey, says head coach Kyle Shanahan, though he can't split them.

The Niners are the only team in the NFL to have booked their playoff spot ahead of the Week 14 games, and they are also in pole position for the NFC's top seed after reeling off five straight wins.

Purdy has enjoyed a breakout campaign in his first full season as San Francisco's starting quarterback, with only the Miami Dolphins' Tua Tagovailoa (3,697) and Houston Texans' C.J. Stroud (3,631) bettering his 3,553 passing yards this year.

He – alongside Dak Prescott and Lamar Jackson – is among the favourites to win the league's top individual prize, though Shanahan believes McCaffrey should also be in contention.

McCaffrey leads the league with 1,177 rushing yards this season, and Shanahan does not see why he couldn't become the first non-quarterback to be named MVP since Minnesota Vikings running back Adrian Peterson in 2012.

"Are you trying to get me in trouble with those two guys?" Shanahan said on Thursday when asked who he would vote for. 

"That's the only reason I wouldn't overly comment on either one of them, because I don't want them to cancel each other out."

Miami's electrifying wide receiver Tyreek Hill is among the non-quarterbacks tipped to be in contention, but Shanahan feels McCaffrey has the strongest case outside the signal callers.

"If any non-quarterback's going to get MVP, I don't get how Christian McCaffrey can't," Shanahan said. "I mean, he's been amazing in what he has done all year.

"If it's going to a quarterback, then I don't have to talk about Christian, I can talk about our quarterback.

"If his numbers are all you see, then I think that solves it. But if you watch the film, then it makes it even stronger, which to me is the most important thing."

The 49ers take on the Arizona Cardinals in their penultimate road game of the regular season on Sunday before facing the Baltimore Ravens – currently the AFC leaders – in a huge clash on Christmas Day.