Brock Purdy insisted the San Francisco 49ers' stellar 2023 season "means nothing" after they went down 27-24 to their NFC West rivals, the Los Angeles Rams, on Sunday.
The Rams trailed 21-7 late in the third quarter and 24-14 in the fourth before scoring 13 points to deal a depleted 49ers team a second defeat of the campaign.
San Francisco were without three of their offensive stars, with Christian McCaffrey on injured reserve and both wide receiver Deebo Samuel and tight end George Kittle also missing out.
But the Rams were also missing some of their key men, with their top two receivers, Cooper Kupp and Puka Nacua, sidelined due to injury.
After starting last season 5-0 on their way to the NFC Championship, San Francisco have failed to build on their Week 1 triumph against the New York Jets this year.
At 1-2, the Niners are well aware that there is plenty of the season left, but they also know missing opportunities like Sunday's may come back to haunt them.
"That's just part of the NFL and being a professional in a professional sport, everybody's really good," Purdy said. "Last year means absolutely nothing.
"And every time you show up on Sunday, you're going to get everybody's best shot. It's the NFL, and we all have to be real with that.
"We have to have the mindset of going and taking it every Sunday and nothing's ever going to be given to us."
The Niners still had the chance to win the encounter, with wide receiver Jauan Jennings delivering a career-best 11 catches for 175 yards and three touchdowns.
In doing so, Jennings became the fourth player in franchise history to have 175 receiving yards and three scores in the same game.
Purdy, meanwhile, didn't miss a beat without his usual weapons, finishing 22-of-30 for 292 passing yards and three touchdowns with a 137.1 passer rating.
However, Purdy didn't get much help from his targets, most notably Ronnie Bell, who dropped a catch in the final quarter to spurn a golden game-winning opportunity.
The loss made Purdy the third 49ers signal caller (alongside Joe Montana and Steve Young) to lose a game in which he completed at least 70% of his passes and threw for three or more touchdowns.
It also dropped the Niners below the .500 mark for the first time with Purdy as their starter, with head coach Kyle Shanahan left furious at the conclusion of proceedings.
"You've got to take their hope away," Shanahan said.
"You give [Rams quarterback Matthew] Stafford too much hope [and] you put a ball in his hands at the end, it's not a situation you want to be in."