Buoyant Scotland will go in search of back-to-back wins over Wales for the first time in 18 years and France travel to Ireland for a mouthwatering Six Nations showdown this weekend.

Scotland ended a 38-year wait for a win at Twickenham on the opening weekend with a dominant 11-6 defeat of the defending champions.

Gregor Townsend's side need to follow that up on Saturday with a victory over a Wales side that got the better of 14-man Ireland at the Principality Stadium following Peter O'Mahony's first-half red card.

France started the tournament by hammering Italy 50-10, but will face a bigger test in Dublin, while England should respond to their Calcutta Cup defeat by beating Italy at home on Saturday.

Ahead of the second round, we preview the upcoming matches with help from Opta.

ENGLAND v ITALY

FORM

The Red Rose have won each of their 21 fixtures against Italy in the Six Nations, and they are the only team yet to suffer defeat against the Azzurri in the championship.

England have hosted Italy on 10 occasions in the Six Nations, winning each of those 10 fixtures by an average margin of 31 points and scoring 5.6 tries per game.

Italy have won just twice away from home in the Six Nations (losing 50 and drawing one), with both victories coming against Scotland at Murrayfield (2007 and 2015).

ONES TO WATCH

George Ford comes into the England side, with captain Owen Farrell moving to outside centre, in one of five changes to the side, and the fly-half will be ready to make a statement after being named on the bench for the loss to Scotland.

Italy endured a torrid start to the competition, but Luca Sperandio scored a fine try. The wing had seven carries and made 52 metres. The Azzurri will need to get Sperandio flying down the flank again in London.

SCOTLAND v WALES

FORM

Scotland were superb against England and will be aiming for consecutive wins over Wales in the Six Nations for the first time since 2002-2003.

Wales had an extra man, but Ireland could consider themselves unfortunate to go down 21-16 in Cardiff. The Welsh have lost their last six Tests away from home and will be in for another huge battle at Murrayfield.

They have conceded 30 points per game in that miserable sequence of matches on their travels.

ONES TO WATCH

Captain Stuart Hogg was man of the match in a rousing performance from Scotland against Eddie Jones' men. The full-back made 112 metres and had 13 carries. He was also brilliant with the boot, kicking for 367 metres.

Louis Rees-Zammit showed why he is so highly rated in Wales' win over Ireland. He dived to finish magnificently in the corner as Wayne Pivac's side made a winning start at home last Sunday.

IRELAND v FRANCE

FORM

Flanker O'Mahony's reckless dismissal proved to be costly for Andy Farrell's Ireland side in Cardiff. They will be looking to avoid suffer back-to-back losses to Les Bleus in the Six Nations, having not endured such a fate since 2010-11.

Ireland have won five of their last seven clashes with France in the Six Nations (L2) after winning only four of their 30 previous meetings with them in the Five/Six Nations (D3 L23).

ONES TO WATCH

Antoine Dupont was the player of the opening round of the tournament. The mercurial scrum-half assisted four tries, the joint-most by any player in a Six Nations match, equalling the record set by Frederic Michalak against Italy in 2006. He also scored a try of his own in a sublime performance.

Ireland lock Tadhg Beirne made the most carries (21) of any player in the opening round. He also hit the most rucks of any player (48) and was Ireland’s joint-highest tackler (10, level with CJ Stander).

Scotland have made three changes to their XV for Saturday's Six Nations clash against Wales at Murrayfield.

Head coach Gregor Townsend has brought in back-row Blade Thomson, centre James Lang and winger Darcy Graham for injured trio Jamie Ritchie, Sean Maitland and Cameron Redpath.

Scotland are seeking consecutive over the Welsh for the first time since 2003 with Townsend in a confident frame of mind after their first Twickenham win over England since 1983 last time out.

"It was a very encouraging performance at Twickenham and the squad performed to a level which has to be the benchmark throughout the tournament," he told Scottish Rugby's website.

"Wales are also coming into this game after a win and will have the same objective, so it will be a tough challenge as always.

"Both teams were involved in physical contests last weekend, and that is evidenced by the injuries Wales and we ourselves have picked up. 

"For us, we are able to bring in three quality players in Blade, James and Darcy. They have been training well and are highly motivated to make the most of this opportunity."

Wales began with a 21-16 win over Ireland in Cardiff and their injury-hit team is boosted by the return of Liam Williams after a three-match ban. 

Williams replaces Hallam Amos, with Gareth Davies taking the number nine shirt and Aaron Wainwright called into the back row, as coach Wayne Pivac makes five enforced changes.

Nick Tompkins and Owen Watkin also come into midfield for George North and Johnny Williams with Dan Lydiate and Tomos Williams also dropping out through injury.

New Zealand-born Willis Halaholo could make his debut off the bench.

Pivac said: "We were pleased to kick the tournament off with a victory last weekend and to be heading to Scotland with a win behind us.

"We continue to build and to move forward and it is great to do that from a position of winning. It is a quick six-day turnaround this week but we are looking forward to getting back out there.

"We have picked up a couple of injuries but we see it as more of an opportunity for those coming into the side."

Scotland team in full

Stuart Hogg; Darcy Graham, Chris Harris, James Lang, Duhan van der Merwe; Finn Russell, Ali Price; Rory Sutherland, George Turner, Zander Fagerson, Scott Cummings, Jonny Gray, Blade Thomson, Hamish Watson, Matt Fagerson.

Replacements

David Cherry, Oli Kebble, WP Nel, Richie Gray, Gary Graham, Scott Steele,  Jaco van der Walt, Huw Jones.

Wales team in full

Leigh Halfpenny; Louis Rees-Zammit, Owen Watkin, Nick Tompkins, Liam Williams; Dan Biggar, Gareth Davies; Wyn Jones, Ken Owens, Tomas Francis, Adam Beard, Alun Wyn Jones, Aaron Wainwright, Justin Tipuric, Taulupe Faletau.

Replacements

Elliot Dee, Rhodri Jones, Leon Brown, Will Rowlands, James Botham, Kieran Hardy, Callum Sheedy, Willis Halaholo.

England head coach Eddie Jones has named a new-look front row and recalled George Ford for the Six Nations game against Italy on Saturday.

The reigning champions went down 11-6 to Scotland on the opening weekend of the 2021 tournament, their first defeat to their Calcutta Cup rivals at Twickenham in 38 years. 

As he looks for a response following that setback, Jones has selected Ford at fly-half in his starting XV, meaning captain Owen Farrell switches to inside centre for the clash with the Azzurri. 

In the pack, the fit-again Mako Vunipola comes in to play opposite fellow prop Kyle Sinckler, while Luke Cowan-Dickie gets the nod at hooker ahead of Jamie George, who is on the bench. 

Courtney Lawes also gets a start at flanker, joining Tom Curry and Billy Vunipola in the back row.  

Ollie Lawrence – who was handed his first Six Nations start against Scotland – is absent from the 23-man squad entirely, with Henry Slade picked to play next to Farrell in midfield.  

"As always, we've picked what we think is our strongest 23 to try and win the game," Jones said.

"We're pleased to have Mako and Kyle back into the team and we've made some changes to our starting XV, but our finishers are just as important to our gameplan. We look at the whole 80 minutes.  

"We've trained very well this week, I've been very pleased with the players' attitudes and work-rate. We're hoping to put on a good performance on Saturday and kick on with our Six Nations campaign." 

England team to face Italy at Twickenham:

Elliot Daly, Anthony Watson, Henry Slade, Owen Farrell (captain), Jonny May, George Ford, Ben Youngs; Mako Vunipola, Luke Cowan-Dickie, Kyle Sinckler, Maro Itoje, Jonny Hill, Courtney Lawes, Tom Curry, Billy Vunipola

Replacements: Jamie George, Ellis Genge, Will Stuart, Charlie Ewels, Ben Earl, Jack Willi, Dan Robson, Max Malins.

Johnny Sexton has hit out at the "inaccurate and highly inappropriate" comments of a French doctor regarding the Ireland star's concussion record.

Dr Jean-Francois Chermann, who stood Sexton down from playing duties for 12 weeks at Racing 92 back in 2014, told RMC Sport on Tuesday that Sexton had suffered approximately 30 concussions in his career.

His remarks came after the fly-half sustained a blow to the head in Ireland's Six Nations loss to Wales, meaning he is undergoing return-to-play protocols ahead of Sunday's visit of France.

Sexton was angered by Chermann's words when addressing the subject in his pre-match news conference.

"I am pretty saddened and shocked by the inaccurate reports that were thrown out yesterday," he said. "We've been here before and it's very frustrating.

"For me, I just think it's totally inappropriate that a doctor that I have seen – many years ago now – felt it was appropriate to come out and talk to whoever it was and say those things.

"It's inaccurate and highly inappropriate and I am pretty disappointed but, for me, I am so used to it, it's almost like water off a duck's back, but for my wife and mum it's very upsetting.

"But that's the world we live in.

"I thought there was patient and doctor confidentiality, I am pretty sure that exists in the world, and I just can't get over the fact that someone thought it was appropriate to just come out of nowhere and just start saying things that weren't even accurate, that's the most hurtful thing."

Aaron Smith says Antoine Dupont is "on another level" to any other player in the world as the mercurial scrum-half strives to end France's Six Nations title drought.

Dupont tormented Italy in the first match of the tournament, proving four assists – equalling compatriot Frederic Michalak's record for a single Six Nations match – and scoring a try of his own in a 50-10 rout at Stadio Olimpico on Saturday.

The playmaker became the seventh man to lay on three or more tries in a game in the competition, also joining Michalak and former number nine Austin Healey as the only players to have been directly involved in five tries in a match in this tournament. 

Dupont was a constant menace to the Azzurri as he pulled the strings in a livewire display before he was given the chance to put his feet up just before the hour mark.

New Zealand scrum-half Smith, who has earned 97 caps and won the Rugby World Cup in 2015, rates the 24-year-old Toulouse pivot as being a cut above any other player on the planet.

Responding to a tweet from the Six Nations official account asking who is the best player in the world, Smith posted: "@Dupont9A this guy is on another level!

"No one is near him atm. He's the point of difference for both his club and country. He's helping me look at parts of my game to improve. #Respect #9Gang"

Ireland will have to keep Dupont quiet at the Aviva Stadium on Sunday when they look to get up and running following a 21-16 defeat to Wales in Cardiff.

Peter O'Mahony has been banned for the next three rounds of Six Nations games following his red card in Ireland's opening defeat to Wales.

O'Mahony was dismissed in the 14th minute of Ireland's 21-16 loss in Cardiff after leading with his elbow to the head of Tomas Francis while attempting a clearout.

The flanker can now not feature for Ireland again until their final match of the tournament, which sees them host England on March 20.

O'Mahony admitted to dangerous play in the ruck and that his actions merited a red card during a disciplinary hearing.

The disciplinary committee deemed the entry point for his offence to be a six-week ban, but halved that suspension after taking into account O'Mahony's record and conduct in the hearing.

In a statement, Six Nations organisers said: "The committee considered all the relevant evidence, including the player's oral evidence, together with the clips of the incident.

"In assessing the seriousness of the offending, the committee found that the offending was reckless."

Ireland will attempt to bounce back on Sunday when they welcome France to Dublin.

Props Kyle Sinckler and Mako Vunipola have returned to the England squad for the Six Nations encounter with Italy at Twickenham on Saturday.

British and Irish Lions duo Sinckler and Vunipola missed the 11-6 Calcutta Cup defeat to Scotland on the opening day of the tournament due to suspension and an Achilles injury respectively.

They will be available to beef up the defending champions' pack against an Azzurri side smarting from a 50-10 hammering at the hands of a rampant France at Stadio Olimpico.

Harry Williams and Tom West will not feature for Eddie Jones' side after they were released to return to their clubs.

The Red Rose never got going in a poor performance versus dominant Scotland, but they won the tournament last year after losing their opening match to France and number eight Billy Vunipola said they can respond again.

He said: "It is frustrating. I won't lie. But this happened last year, and we managed to pull it back so it's massive for all of us to make sure we get around each other and whatever we need to fix this week we do as soon as possible.

"We only have a week to do it, which is probably the best thing for us. We don't have a fallow week to let that settle in and frustrate us.

"You never really forget these days, you never really forget these moments, and to be honest I don't really want to forget them.

"I want to move on from it, but I don't want to forget it as it keeps you sharp. Losing like this at Twickenham is never what you dream of."

Uncapped duo George Taylor and Charlie Shiel have been called up to the Scotland squad for the Six Nations clash against Wales along with D'Arcy Rae.

Gregor Townsend drafted in centre Taylor, scrum-half Shiel and prop Rae for the round-two encounter at Murrayfield on Saturday between two sides on a high following winning starts.

Rae earned his only cap against Ireland in 2019, coming off the bench in a 22-13 loss.

Ewan Ashman, Blair Kinghorn, Jamie Dobie and Rufus McLean have been released back to their clubs.

Scotland dominated defending champions England on the opening day of the tournament, ending a 38-year wait for a win at Twickenham with an 11-6 victory on Saturday.

Captain Stuart Hogg said they will remain grounded after regaining the Calcutta Cup.

The full-back, who was named man of the match in the defeat of Eddie Jones' side, said: "We are not going to get ahead of ourselves. We will enjoy this one, no doubt, but then it is on to Wales next week.

"We'll get back on the horse and ready to go because next week is another challenge for us and one we're really excited about."

Wales are set to be without four players for their Six Nations clash with Scotland next Saturday as they count the cost of a hard-fought win over Ireland.

Wayne Pivac's men had to recover from a first-half blip as they surrendered a 6-0 lead to 14-man Ireland after the visitors had Peter O'Mahony sent off for leading with the elbow to the head of Tomas Francis.

Ireland went into the break 13-6 ahead despite their personnel disadvantage, but tries from George North and Louis Rees-Zammit proved enough for Wales to claim a 21-16 victory.

However, it was something of a pyrrhic triumph with Johnny Wiliams and Hallam Amos poised to miss the visit to Murrayfield with head injuries, while Pivac also ruled out Tomos Williams with a hamstring issue and Dan Lydiate, who is suspected to have a knee ligament problem.

"We've picked up a few injuries so we're looking at those now, we'll make a better assessment [on Monday]," Pivac said.

"We're sort of counting the walking wounded after that one.

"The six-day turnaround means certain players won't be playing for us, two with the head knocks. A six-day turnaround means any head knocks, you're gone.

"Unfortunately we lose a couple of players straight away. We'll see how the rest of the squad is [on Monday] and look at what sort of side we can put together on Tuesday.

"Johnny Williams went off for a HIA [head injury assessment] and didn't come back on. The other one was Hallam Amos who took a late knock too. Those are the two head knocks.

"Then we've got a hamstring for Tomos Williams – we're hoping that's not serious but it won't turn round in six days, I wouldn't have thought."

Pivac added of Lydiate: "We're going to get that scanned but it's not looking too good. It could be an ACL but we'll get that scanned for a definite result.

"It's very disappointing for Dan and he's very disappointed in the changing room right now."

Ireland coach Andy Farrell, meanwhile, expressed confidence O'Mahony will make amends for his indiscretion, telling BBC Sport: "We've seen red cards for that in the past haven't we?

"I think we've seen yellow cards for other incidents that didn't quite go our way.

"He's been around enough a long time and he's gutted. He's been a pretty stalwart player for us in the past and he'll continue to do so in the future."

Wales took advantage of Peter O'Mahony's early dismissal and survived a fightback from 14-man Ireland to start their Six Nations campaign with a 21-16 win in Cardiff.

O'Mahony was sent off in the opening 15 minutes for contact to the head but Andy Farrell's men overcame their disadvantage in personnel to lead 13-6 at the interval.

But tries from George North and Louis Rees-Zammit turned the contest back in Wales' favour, with Ireland unable to produce another riposte.

The visitors were also dealt a late blow as Johnny Sexton went off with a head injury, giving Farrell plenty to worry about ahead of next week's clash with France.

Ireland were pinned for side entry at the ruck in the opening five minutes, giving Leigh Halfpenny the chance to boot Wales into a three-point lead.

O'Mahony was guilty of a much more serious infraction in the 14th minute, the flanker seeing red for leading with the elbow to the head of Tomas Francis as he attempted a clearout.

Wales, who earlier lost Dan Lydiate to a leg injury, doubled their advantage four minutes later through Halfpenny's trusty right peg.

However, Ireland enjoyed the majority of possession and territory thereafter in the first half and were rewarded for an extremely spirited fightback.

A pair of Sexton penalties drew Ireland level and a break from Robbie Henshaw then enabled Tadhg Beirne to dive over and give them a seven-point lead to defend.

Wales saw scrum-half Tomos Williams suffer a hamstring injury on the stroke of half-time but his absence did not prevent the hosts from getting back into the contest.

North capitalised after a series of Ireland handling errors to surge through a gap on the right and touch down, but Halfpenny misjudged the conversion attempt.

But that instance of profligacy from the tee did not prove costly as Rees-Zammit produced a stunning finish in the right-hand corner to put Wales back in front.

Halfpenny atoned for his earlier miss with a superb kick from the sideline to add the extras before knocking over a more routine kick as a penalty made it 21-13.

Billy Burns trimmed the deficit back to five points shortly after Sexton's exit but he failed to find touch with a penalty as he attempted to push Ireland to the five-metre line in stoppage time as Wales survived a dramatic final push from the visitors.

Gregor Townsend praised the "calmness" and "togetherness" that saw Scotland end 38-years of Twickenham hurt, as Eddie Jones took responsibility for England's Calcutta Cup defeat.

Defending Six Nations champions England were caught cold by a dominant Scotland showing at an empty Twickenham, a venue where the visitors had not beaten their rivals since 1983.

Stuart Hogg and Finn Russell were influential in a game marking the 150th anniversary of this fixture, while rookie Cameron Redpath impressed and Duhan van der Merwe scored the game's only try in an 11-6 win.

Reflecting on a famous victory with ITV Sport, Scotland coach Townsend said: "I think there was just a calmness about how we played, a togetherness and an effort level that was superb. 

"We had a really good feeling with the way we trained and bonded. But you never know, it's the first game of the championship, there were a few who had their first game for a while or debuts. It was above expectations but what a start to the championship.

"It's impressive, to win here is very tough. Our line-out was superb, we really respect England's set-piece, their line-out has been outstanding the last couple of years.

"We put pressure on lines-outs, the scrums were good – then we were accurate in attack. It's difficult in these conditions to go wide, which we did. The kicking was excellent and so was the players' leadership – you could hear them in this empty stadium."

Captain Hogg revelled in the win but insisted the focus quickly turns to next week's home clash against Wales.

"It's amazing for us, I think we can't control what happened in the past that's gone, we can control what happens in the future," Hogg said, 

"We were a credit to a man, credit to England they provided a tough challenge. We stood up to it.

"We got excited during the week, we knew we could come down here and put in a performance. We looked after the ball in attack, went for multi-phase and caused England problems. We'll enjoy this one then it's onto Wales."

England also lost their 2020 Six Nations opener to France but rebounded to win a championship delayed by the coronavirus pandemic.

The hosts were left lacking in both the possession stats and penalty counts, and head coach Jones said the buck lies with him.

"Firstly congratulations to Scotland, they played very well, played with a lot intent and a lot of spirt, we just had one of those days, maybe I didn't prepare the team right, we were a long way from our best," Jones said.

"You just have days like that. It's my responsibility, every time a team goes on the pitch it's a head coach's responsibility."

England's midfield pairing of Henry Slade and rookie Ollie Lawrence struggled to get into the game but Jones had a simple reason to explain that.
"You've just got to look at the possession stats, they had 75 per cent possession, a penalty count of 10 to one. That's why the centres didn't touch the ball, it's the basics of rugby," he added.

"It is what it is, we get the players, we accept responsibility for the players, I accept responsibility for not getting players ready for this game."

Eddie Jones questioned whether Scotland could handle the "weight of expectation" and they provided the sweetest of answers by ending a 38-year wait for a win at Twickenham.

Time and again Scotland had failed to beat their fierce rivals in their own backyard, but that elusive victory finally came as they regained the Calcutta Cup on a wet Saturday evening in London.

Gregor Townsend's side dominated the Six Nations champions on the opening day of the tournament, winning 11-6 to leave England head coach Jones with a face like thunder.

Jones will be asking why his ill-disciplined side started the defence of their title with such a flat, insipid performance in a game that marked the 150th anniversary of rugby's oldest fixture

Scotland had produced a sensational fightback to draw 38-38 at the same venue two years ago, before being denied an astonishing victory late on.

They never looked like suffering more heartbreak on this occasion, Stuart Hogg leading by example as they won at the famous stadium for the first time since 1983 to leave England shellshocked.

Scotland certainly did not resemble a team who might be feeling the pressure as they bossed the game from start to finish.

The Red Rose, starting the tournament with a depleted pack, were guilty of indiscipline time and again, with referee Andrew Brace losing patience when he sent Billy Vunipola to the sin bin.

Finn Russell deservedly put Scotland in front with a penalty early on and almost set up a try for Duhan van der Merwe with a clever kick, but the leaping wing was unable to grab a high bouncing ball and touch down.

Van der Merwe was not to be denied soon after, fending off Mark Wilson's tackle to put Scotland 8-0 up on the half-hour mark, but Scotland suffered a blow when Russell was yellow-carded just before the break for tripping Ben Youngs.

The boot of Farrell reduced the deficit to two points at the interval, with Scotland surely heading to the dressing room thinking they should have been further ahead after being frustrated by resolute England defending.

Russell returned with Scotland still leading and they continued to boss possession, managing the game superbly, and the fly-half's second penalty put them 11-6 up before he missed another shot at goal.

A furious Jones marched from the stands to the touchline to try and turn the tide, replacing Jamie George and Youngs with Luke Cowan-Dickie and Dan Robson before the hour-mark.

The excellent Hogg kept them on the back foot with a sublime, mammoth kick into the corner - not for the first time - and England were warned over their penalty count again, but more desperate defence denied Scotland a second try as they continue to hammer at the door.

Lacklustre England's day was summed up when Jonny May knocked on under no pressure in the closing stages.

Hogg said Scotland felt ready to "create a little bit of history" and start a "new chapter" this weekend and, as they finally celebrated on the Twickenham turf, it was evident the Red Rose had failed to live up to expectations.

Scotland ended a 38-year wait for victory over England at Twickenham as a hard-working and industrious display earned a deserved 11-6 triumph and Calcutta Cup glory.

Not since 1983 had Scotland beaten their biggest rivals at the home of English rugby but the fired-up visitors outbattled and outplayed Eddie Jones' defending Six Nations champions.

Finn Russell and Stuart Hogg were the attacking catalysts in a match marking the 150th anniversary of the first meeting between these old foes.

Rookie Scotland centre Cameron Redpath showed why there is so much hype with a promising display in an empty stadium due to the coronavirus pandemic that delayed the finish to the 2020 championship.

England were without five forwards but even accounting for that the penalty count was much too high and they were lucky to only be 8-6 down at the break – Duhan van der Merwe crossing for the game's only try.

The end result is a third Calcutta Cup in four years for Scotland, who had previously lost nine in a row between 2008 and 2017.

England's ill-discipline allowed Russell to boot over an early penalty and an accumulation of infringements led to the sin-binning of Billy Vunipola for a high, albeit loose, arm on Scotland's number 10.

Buoyed by the extra man Hamish Watson was held up at the line by Jamie George and only a cruel bounce denied Van der Merwe from meeting Russell's expert kick.

Another bomb from Russell set in motion the move from which Van der Merwe bulldozed through Mark Wilson's tackle shortly after as Scotland had reward for their dominance.

But skipper Owen Farrell quickly kicked the hosts onto the board before Russell was binned for a crude trip on Ben Youngs and another three-pointer from England's captain brought the score within two.

The numerical disadvantage did little to curb Scotland's enthusiasm early in the second half and Russell kicked a routine penalty after Ellis Genge was harshly pinged for not attempting to bind with a low tackle.

Russell missed with another effort that he will feel he should have made but still England struggled to garner any momentum.

Stuart Hogg was also off target from the tee to make it a nervy ending, but the final whistle was met with shouts of joy from the visitors.

England's depleted pack lacks punch

There is a sense of deja vu for England who lost the opening match of their 2020 title-winning campaign to France.

The absence of Mako Vunipola and Kyle Sinckler clearly weakened a usually strong pack, while Joe Marler, Joe Launchbury and Sam Underhill were also absent. Without some key men, England lacked their usual set-piece prowess.

Russell and Hogg torment England

A year ago it looked as though Russell's international career may be over following a breakdown in the relationship with head coach Gregor Townsend.

His return to action for the 2020 finale was ended early due to an injury that ruled him out of the Autumn Nations Cup, but Scotland fans will be delighted their fly-half wizard has patched things up with Townsend after his magic helped seal a famous win.

He was helped by the brilliant Hogg, whose pin-point kicking and lightning-quick feet was a constant thorn in the side of an out-of-sorts England.

What's next?

England are at back at HQ as they aim to bounce back next Saturday when Italy visit Twickenham, the same day Scotland – who will now fancy a real crack at the title – host Wales at Murrayfield.

Scotland ended a 38-year wait for victory over England at Twickenham as a hard-working and industrious display earned a deserved 11-6 triumph and Calcutta Cup glory.

Not since 1983 had Scotland beaten their biggest rivals at the home of English rugby but the fired-up visitors outbattled and outplayed Eddie Jones' defending Six Nations champions.

Finn Russell and Stuart Hogg were the attacking catalysts in a match marking the 150th anniversary of the first meeting between these old foes.

Rookie Scotland centre Cameron Redpath showed why there is so much hype with a promising display in an empty stadium due to the coronavirus pandemic that delayed the finish to the 2020 championship.

England were without five forwards but even accounting for that the penalty count was much too high and they were lucky to only be 8-6 down at the break – Duhan van der Merwe crossing for the game's only try.

The end result is a third Calcutta Cup in four years for Scotland, who had previously lost nine in a row between 2008 and 2017.

England start their quest to retain the Six Nations title against Scotland on Saturday just over three months after they were crowned champions. 

The Red Rose dethroned Wales at the end of October, pipping France on points difference in a dramatic finale to a tournament that ended almost nine months after it started due to the COVID-19 pandemic. 

Eddie Jones' side are favourites to win the competition again, but Les Bleus are also well fancied to end an 11-year wait for Six Nations glory and face Italy in the first match. 

England do battle with Scotland for the Calcutta Cup at Twickenham, with Wales and Ireland locking horns in Cardiff on Sunday. 

Ahead of the opening round, we preview the upcoming matches with help from Opta.

ITALY v FRANCE

FORM

France have won 19 of their 21 previous Six Nations matches against Italy (L2), including their last seven in a row. Their two defeats in that time both came in Rome, in 2011 and 2013.  

Italy have lost their last 27 Six Nations matches, the longest losing streak in the history of the competition. Their last victory came at Murrayfield against Scotland in 2015, while they have not won at home since 2013. 

Les Bleus achieved a cumulative points difference of +31 in the first 20 minutes of their 2020 Six Nations matches. No other side managed a positive double-digit points difference in that period of matches, but Italy had a -39 difference. 

ONES TO WATCH

France wing Teddy Thomas scored a try in his last Test against Italy and is capable of lighting up the tournament. He can get off to a storming start in Rome.

Paolo Garbisi caught the eye at fly-half last year after being handed his debut against Ireland in October. Hopefully for his country, there is still much more to come from the 20-year-old.

ENGLAND v SCOTLAND

FORM

The last time England hosted Scotland in the Six Nations they drew 38-38 two years ago. Scotland clawed back the biggest ever half-time deficit (-24 pts, 7-31) by a side to avoid defeat in the tournament’s history, almost snatching victory before a late George Ford try denied them. 

Scotland have never beaten England at Twickenham in the Six Nations (D1, L9), their last victory against them the Red Rose at the London venue came in 1983 in the Five Nations (22-12).  

Gregor Townsend's side concluded the 2020 edition by winning their last three games in a row, their best run in the Championship since Italy joined in 2000. 

ONES TO WATCH

England captain Owen Farrell has scored exactly 1,000 Test points, one of just six men to reach that milestone. He is just four points away from reaching a century against Scotland.

Finn Russell returns to the Scotland side and the creativity provided by the fly-half will be key for Townsend's men.

WALES v IRELAND

FORM

Wales have lost their last two home games in the Six Nations, the last time they suffered three consecutive defeats at home was in 2002-03. Wayne Pivac's side have lost their last four games in the competition, their worst streak since 2006-07 (L5).  

No team scored more tries than Ireland in the Six Nations last year (17, along with France), four of those were launched from the back of a scrum. Wales (2) were the only other side to score multiple tries following a scrum.  

Ireland scored seven tries in the final quarter of their fixtures in 2020, more than any other side. Wales, meanwhile, scored the joint-second most in that period (6, level with England). 

ONES TO WATCH

Louis Rees-Zammit turned 20 this week and the Wales wing can celebrate in style with a livewire display at the Principality Stadium.

Ireland centre Garry Ringrose had terrible luck with injuries last year, but he is ready to fire on all cylinders in 2021.