Kyle Shanahan needs to get the San Francisco 49ers winning again if their playoff potential is to be fulfilled, and this Sunday looks like a major opportunity.

To snap a three-game losing streak, the Niners (2-3) must get the better of an Indianapolis Colts side who, much like San Francisco themselves, have made an inconsistent start to the season.

By contrast, the Tampa Bay Buccaneers are riding a three-game run of wins and have started 5-1 for just the fifth time in the history of the franchise, heading into a tussle with the Chicago Bears (3-3). Tom Brady has been a driving force so far as the Super Bowl winners carry on where they left off last season.

Patrick Mahomes has been hit and miss for the slow-starting Kansas City Chiefs, who will hope the NFL's highest-paid player can cut out throwing interceptions as they face the Tennessee Titans.


Indianapolis Colts @ San Francisco 49ers

If coach Shanahan's 49ers are to turn around their season, then facing a Colts side who have begun 2-4 seems like a pretty good place to start. Yet the Colts have dominated this series of late, winning on their last four meetings, albeit most recently in 2017 when they snatched a 26-23 overtime success. It would not be stepping out of line to predict this could be tight, given the 49ers have played nine consecutive games that have been decided by eight or fewer points, going back to last season.

That is the longest active streak of such close games in the NFL and the longest streak in team history, and the Niners do not have the best recent return when games go close, posting a 3-6 record in this sequence.

San Francisco fell 17-10 to the Cardinals in their most recent game, two weeks ago, while the Colts hot-footed their way to a 31-3 trouncing of Houston last Sunday. That came despite Indianapolis earning just 15 first downs for the entire game. It was the first time the Colts had won by 28 or more points while only having 15 or fewer first downs since 1972 against New England.

In his 21st career game, Colts running back Jonathan Taylor rushed for 145 yards and two touchdowns, meaning he surpassed 1,500 rushing yards, 500 receiving yards and chalked up his 15th rushing touchdown in the NFL. Only four running backs in NFL history have hit all three of those milestones in fewer games than Taylor, with two of those doing so with the Colts – Edgerrin James and Marshall Faulk.

San Francisco will hope to be recharged after a bye week. Deebo Samuel scored the fourth rushing touchdown of his career against the Cardinals, with Jerry Rice (10) the only wide receiver with more rushing touchdowns in 49ers history.

Chicago Bears @ Tampa Bay Buccaneers

After a dispiriting loss to the Green Bay Packers last time out, the Chicago Bears encounter a Tampa Bay team in sparkling recent form. Tampa Bay have started the season 5-1, doing so for the fifth time in franchise history, and on each of the previous occasions (2005, 2002, 1997 and 1979) they backed it up by reaching the playoffs. History could be made on Sunday, given the Buccaneers have never started a season with six wins through their first seven games.

Yet this is a game in which the Bears have traditionally, and recently, had the upper hand. Chicago have stacked up 40 wins in 60 all-time meetings against Tampa Bay, which is the most wins by any team against the Bucs. The Bears have also won the last two in the series, scoring victories in 2018 and 2020.

Tampa Bay can seemingly do no wrong when Brady is pulling the strings so masterfully. Brady leads the NFL with 2,064 passing yards, the second-highest total he has ever had through six games of a season – beaten only by his 2,163 passing yards at this stage in 2011. Prior to this year, no Tampa Bay quarterback had ever thrown for more than 1,800 yards through six games.

What have the Bears got to offer? Chicago are averaging 246.2 net yards per game, which is more than 20 yards per game less than any other team. The 1,477 yards is the fewest Chicago has had through six games since the 1993 season. Rookie quarterback Justin Fields needs to make something happen, but others must step up too. In his first career start, Khalil Herbert ran for 97 yards and a touchdown against Green Bay last time out.

Kansas City Chiefs @ Tennessee Titans

"He's trying to make things happen," said Chiefs head coach Andy Reid, explaining away the two interceptions thrown by Patrick Mahomes in Week 6 against Washington. For Mahomes, that was a second straight game with at least two interceptions. He is tied with Jacksonville's Trevor Lawrence in second position on the list of the most interceptions thrown this season, with his tally of eight so far only topped by Zach Wilson of the Jets.

This is only the second run that Mahomes has endured of throwing two or more interceptions in consecutive games, the previous dating back to Week 5 and 6 of the 2018 season, and Reid will hope his radar is better set for the clash with the Titans. Mahomes is still doing an awful lot right in 2021, but the fact remains he threw just six interceptions last season.

The Chiefs' unsteady 3-3 opening is their worst of the Mahomes era, and it was 2015 when they got off to a slower start. On that occasion they followed a 1-5 opening with 10 consecutive wins, a single-season record for Kansas City that was matched last season.

Tennessee's bright start has featured some notable performances. The Titans ran for 146 yards and scored four rushing touchdowns in the 34-31 win over Buffalo on Monday night, taking them to 985 rushing yards and 12 rushing touchdowns for the season. It is the first time in franchise history that the Bills have 10 or more rushing touchdowns and at least 975 rushing yards through six games.

Running back Derrick Henry has 10 rushing touchdowns so far, beating his career best of seven through six weeks in 2020. It puts him tied for the fourth most rushing touchdowns of all time through six weeks (Jim Brown 14, Shaun Alexander 12, Emmitt Smith 11).

Elsewhere...

The Detroit Lions face a tall order on the road against the Los Angeles Rams (5-1). Detroit are 0-6 for the first time since their 0-16 season in 2008 and have not scored more than 17 points in any of their last five games. Former Rams quarterback Jared Goff, now with Detroit, has thrown zero touchdown passes and an interception in each of his last two games.

The 5-1 Baltimore Ravens have recent history on their side ahead of a clash with the Cincinnati Bengals, having won five successive games in their head-to-head series, including the last three by a brutal average of 31.7 points.

Heading into a home game against the Houston Texans (1-5), the Arizona Cardinals are on a 6-0 roll. This has only happened twice before in franchise history, but never before in Arizona. The St Louis Cardinals in 1974 and Chicago Cardinals in 1922 are the teams who both started their seasons 6-0 as well.

Philadelphia QB Jalen Hurts could match an NFL record as the Eagles (2-4) tackle the Las Vegas Raiders. Hurts has rushed for two touchdowns in each of his last two games. Billy Kilmer, for San Francisco in 1961, is the only quarterback to achieve the feat in three straight games.

The Green Bay Packers last lost at home to Washington in 1988, winning five in a row since with home-field advantage, and they put a 5-1 season record to the test when the teams meet again. Washington (2-4) are yielding an NFL-worst 31.0 points per game in 2021, matching the team's worst mark through six games of a season in the Super Bowl era (1998).

Time flies when you're having fun, as the old cliche goes, but you don't need to have been enjoying yourself to notice how quickly we got to Week 7 of the NFL season.

Fantasy managers who have enjoyed strong starts may already be casting their eyes towards the playoffs and a run at the title.

Meanwhile, those owners who are mired near the bottom of their league might be wondering where it all went wrong and paying a dwindling amount of attention to their line-up.

Either way, there are plenty of players with matchups this week who can help deliver a win for your squad. Stats Perform looks at four offensive players and a defense who are primed to make a significant impact in Week 7.

 

Quarterback: Matt Ryan, Atlanta Falcons @ Miami Dolphins

The Falcons have had the bye week to rest after their win over the New York Jets in London and now get the chance to exploit another vulnerable AFC East defense.

They face a Dolphins team that will be playing only seven days removed from their game in the United Kingdom, and a defense that gave up 319 passing yards in their loss to the lowly Jacksonville Jaguars.

Ryan has two 300-yard games to his name this year and has thrown for multiple scores in every game after drawing a blank in the season opener.

Atlanta and Miami look like two teams heading in different directions, expect Ryan and the Falcons to take advantage and the 2016 MVP to record a big fantasy day.

Running Back: Chase Edmonds, Arizona Cardinals vs. Houston Texans

Edmonds has been something of a frustrating case so far this season.

He is averaging six yards per carry but has not consistently received the workload to be a viable fantasy option.

That looks likely to change this week when the unbeaten Cardinals face the 1-5 Texans, who are allowing 4.74 yards per rush attempt, the fifth-worst average in the NFL.

With the Cardinals widely expected to get out to a big lead in a hurry, Arizona should be able to take the pressure off Kyler Murray and lean on their backs if the game gets out of hand, meaning Edmonds could be in store for plenty of garbage time yards.

Wide Receiver: Ja'Marr Chase, Cincinnati Bengals @ Baltimore Ravens

Chase is a fully fledged fantasy darling having exploded out of the gates as a rookie for 553 yards and five touchdowns.

He might be expected to hit a block in the road against a Ravens defense that only gave up six points to the Los Angeles Chargers last week.

However, Chase is tied for the league lead with eight receiving plays of 25 yards or more and only six teams have allowed more passing plays of 20 yards or more than the Ravens (24).

Keep the faith and look for Joe Burrow and Chase to connect on at least one big one to vindicate his starting spot in fantasy line-ups.

Tight End: Dallas Goedert @ Las Vegas Raiders

With Zach Ertz out of the picture following his trade to the Arizona Cardinals, expect a bump in targets for Goedert, who is averaging 14.4 yards per reception this season.

That increase in his share of the workload could hardly come at a better time for Goedert fantasy owners, as he and the Philadelphia Eagles travel to visit a Raiders team allowing the most fantasy points per game to opposing tight ends.

Defense: New England Patriots vs. New York Jets

This one isn't too difficult. The Jets have committed nine giveaways this season, tied for sixth-most in the NFL, and four of those came from Zach Wilson interceptions against the Patriots at MetLife Stadium in Week 2.

Wilson and Co. have got themselves in the win column since then, but there is nothing to suggest that a Jets offense still without left tackle Mekhi Becton should succeed in avoiding turnovers in this week's return fixture in Foxborough.

Arizona Cardinals star Kyler Murray said he enjoyed a "little more freedom" in the absence of Kliff Kingsbury after the NFL's hottest team preserved their perfect start to the season.

Kingsbury missed Sunday's clash against the Cleveland Browns after testing positive for coronavirus, but the high-flying Cardinals – the only undefeated franchise remaining – still won 37-14 to improve to 6-0.

Defensive co-ordinator Vance Joseph and assistant head coach/special teams co-ordinator Jeff Rodgers stepped up to share responsibilities in Kingsbury's absence, while assistant wide receivers coach Spencer Whipple was calling plays in Murray's ear.

Murray was 20-of-30 passing for 229 yards and four touchdowns as the Cardinals won six straight games for the first time since Weeks 7-16 of the 2015 season.

"I think once we got the news, it was just an opportunity," Cardinals quarterback Murray said post-game.

"Kind of exciting to go prove ourselves on the road against a great team. I think you could feel the energy before the game."

"That may be a product of not having a coach out there, just having a little more leeway," Murray said after becoming the first Cardinals QB since 1950 with a 100-plus passer rating in five of the team's first six games of a season.

"I guess that did give me a little more freedom, just to whatever I did see, go with it and that's what Whipple's saying to me the whole time: 'Whatever you see'. And I stick to that same rule, as long as it makes sense. You got a plan and go with it."

The Cardinals are 4-0 on the road and have won each game by no fewer than 12 points – in their franchise history, Arizona had never won four consecutive away games by double digits.

On Kingsbury's absence, stand-in coach Joseph added: "It was really seamless".

"It's been an up and down week, but our team leaders were great all week," Joseph said. "No one wavered, no one blinked. The staff didn't blink. Every day it was bad news and no one blinked - not one time. Even yesterday. Even Saturday morning at practice when the players knew that Kliff was down for the game, there were no worries.

"There was really an excitement to go play a really good football team. The boys performed. This staff is amazing. It's a great football staff. It's our third year all together and that helps - having continuity like this."

Baker Mayfield's troublesome left shoulder popped out of joint twice during the Cleveland Browns' 37-14 NFL loss to the Arizona Cardinals on Sunday, but the quarterback "absolutely" expects to face the Denver Broncos in Week 7.

Mayfield initially injured his non-throwing shoulder against the Houston Texans on September 19, suffering a partially torn labrum, and the Browns star has worn a brace in subsequent games. 

That extra protection could not save him when Arizona's J.J. Watt hauled him to the ground in the third quarter, forcing a fumble and leaving Mayfield on the ground in pain. 

But Mayfield returned to the game when the Browns got the ball back and finished 19-of-28 passing for 234 yards with two touchdowns and an interception. 

Case Keenum finished the game at quarterback for Cleveland once the score got out of hand, but Mayfield said he was confident he would be cleared to play the Broncos on Thursday, despite meeting the media with his left arm in a sling. 

"It feels like s***," he said of his shoulder, adding: "It dislocated again [on the Watt sack] and then slipped out again on a non-contact play, so just got to figure out a way to get better."

Mayfield was sacked five times as the Browns played without their usual starting tackles Jedrick Wills Jr. and Jack Conklin. 

"It was just one of those days," Mayfield said. "We couldn't get things going, they had a good plan for us and we got punched in the mouth."

Mayfield and the Browns will have to recover quickly as they face what has become a critical game against the Broncos.

Cleveland entered the year fancied as possible Super Bowl contenders and suffered a tough season-opening loss to reigning AFC champions the Kansas City Chiefs before reeling off three straight wins. 

The Browns now sit at 3-3 after a wild loss to the Los Angeles Chargers in Week 5 and Sunday's blow-out defeat. 

"We're going to see what we're made of," Mayfield said. "Our backs are against the wall. I like our chances."

The Cowboys came from behind twice in the fourth quarter to force overtime before Dak Prescott's touchdown pass in the extra session gave Dallas a 35-29 victory over the New England Patriots on Sunday. 

Prescott hit a wide-open CeeDee Lamb from 35 yards out with just under four minutes to play in overtime for the victory, the final strike in a game that saw the Dallas quarterback complete 36 of 51 passes for 445 yards and three TDs. 

The final touchdown capped a wild final few minutes in Foxborough, where Trevon Diggs momentarily stunned the New England crowd by intercepting rookie quarterback Mac Jones and returning it 42 yards for a score to give Dallas a 26-21 lead with 2:27 remaining in the fourth quarter. 

Diggs has intercepted a pass in every game this season, with seven picks overall, and has returned two of them for touchdowns. He is the first NFL player in the Super Bowl era (since 1966) to intercept at least seven passes with multiple touchdowns in his team's first six games of the season. 

But Jones answered on the very next play, hitting Kendrick Bourne for a 75-yard touchdown and passing for the two-point conversion to give New England a 29-26 lead with 2:11 to play. 

That was too much time to leave Prescott, though, and he drove the Cowboys (5-1) downfield to set up kicker Greg Zuerlein – who had missed from 51 yards minutes earlier – for a 49-yard field goal that sent the game to overtime. 

After the Dallas defence forced New England (2-4) to punt in the first possession of overtime, Prescott completed all five of his pass attempts on the game-winning drive. 

The Cowboys racked up 567 yards of total offence on the day, the first time the Patriots allowed at least 500 yards in a game since surrendering 538 to the Philadelphia Eagles in losing Super Bowl LII four years ago. 

Murray, Cardinals stay unbeaten

Kyler Murray threw four touchdown passes as the Arizona Cardinals remained the NFL's only unbeaten team with a 37-14 rout of the Cleveland Browns. 

Murray completed 20 of 30 passes for 229 yards and did not throw an interception as Arizona – without head coach Kliff Kingsbury due to COVID-19 – built a 20-0 lead, then saw Cleveland come back before half-time before pulling away after the interval. 

Baker Mayfield tossed a pair of touchdowns in the final 5:06 of the opening half before suffering a shoulder injury as the Cardinals' defence held Cleveland scoreless after the break on the way to their first 6-0 start since 1974.

In Denver, the Las Vegas Raiders held off the Broncos 34-24 in Rich Bisaccia's first game as interim head coach after Jon Gruden's resignation Monday. 

The unbeaten Arizona Cardinals will be without head coach Kliff Kingsbury on Sunday after he tested positive for coronavirus.

Arizona announced on Friday that Kingsbury had contracted COVID-19, ruling him out of the NFL clash with the Cleveland Browns.

Cardinals quarterbacks coach Cam Turner and defensive tackle Zach Allen will also be sidelined against the Browns following positive tests.

Defensive co-ordinator Vance Joseph and assistant head coach/special teams co-ordinator Jeff Rodgers will share head coach responsibilities in Kingsbury's absence.

The Cardinals lead the NFC West and are the NFL's lone undefeated team at 5-0 as they look to stay perfect this week.

This is the fifth time the Cardinals – an original NFL franchise – have won their first five games but first time since moving to Arizona. They did it twice as the Chicago Cardinals (1922 and 1923) and twice as the St Louis Cardinals (1966 and 1974), per Stats Perform.

Arizona quarterback Kyler Murray has attempted at least 30 passes and completed more than 70 per cent of them in each of his last four games – that matches the longest such streak by a Cardinals player over the last 60 seasons. Kurt Warner had a four-game streak of that kind in 2008.

On the list of teams built to potentially end the Arizona Cardinals' unbeaten start to the season, the Cleveland Browns are near the top.

However, the Browns are tasked with dealing the Cardinals their first loss of the season without their best offensive player, with running back Nick Chubb ruled out because of a calf injury.

That blow robs the Browns of a runner who is second only to Tony Pollard of the Dallas Cowboys (6.37) in yards per attempt among running backs with 5.81 and is also second with 14 runs of 10 yards or more through five games of the 2021 campaign.

Second to Pollard (4.56) among backs with at least 10 attempts in yards per carry on plays where a defender disrupts the run, Chubb (4.21) stands as arguably the elite running back in the NFL, his remarkable blend of vision, elusiveness, power and speed helping establish him as the focal point of Cleveland's attack.

Yet they may still be able to succeed against the Cardinals' defense without Chubb in their backfield.

While the Cardinals have done an excellent job keeping opponents out of the endzone – their 82 offensive points allowed are the third-fewest in the league – they have struggled to contain opposing running backs.

Arizona's defense has allowed an opponent rushing average of 5.39 yards per carry; only the Los Angeles Chargers (5.59) have performed worse in that regard.

And the Browns do have an extremely reliable reserve to call upon to take advantage of that weakness.

Kareem Hunt is averaging 5.36 yards per carry and, reflecting his ability to stay on his feet through attempted tackles, leads all backs with at least 10 carries with 3.10 yards after contact per rush.

Cleveland's success on the ground is a testament to the strength of their offensive line.

Every member of the Browns' starting offensive line has a double-team adjusted run-block win rate of at least 79 per cent, though tackles Jedrick Wills and Jack Conklin are both questionable for Sunday.

Conversely, only three members of Arizona's defensive front have a double-team adjusted run defense win rate above 30 per cent.

In other words, the Browns have a clear matchup advantage in the run game and, even without Chubb, have a back with the ability to exploit it.

Cleveland's run game made a huge contribution to them scoring 42 points in a losing effort against the Chargers last week. With MVP candidate Kyler Murray helming an often explosive offense, they may need a similar showing this week to improve to 4-2. Thankfully, Hunt is more than capable of delivering such a performance. 

The Philadelphia Eagles have traded three-time Pro Bowler Zach Ertz to the Arizona Cardinals.

The 30-year-old tight end forged what the team described as a "special legacy" in an eight-year spell in Pennsylvania that included winning Super Bowl LII.

Ertz joined the Cardinals in exchange for a fifth-round draft pick in 2022 and rookie cornerback Tay Gowan, it was confirmed on Friday.

Ertz's defining moment for the Eagles came in the Super Bowl defeat of the New England Patriots three years ago, his 11-yard catch and drive for the end zone late in the fourth quarter helping to secure a 41-33 victory.

A second-round pick in 2013, Ertz made an NFL-record 116 receptions in 2018 and is second only to Harold Carmichael for catches in Eagles history, making 579 in the regular season and 33 in the playoffs.

He signed off in style on Thursday, scoring a touchdown in the 28-22 loss to the Tampa Bay Buccaneers at Lincoln Financial Field in what proved to be his final appearance for the franchise.

"Zach Ertz built a special legacy in Philadelphia," said chairman and CEO Jeffrey Lurie. "Talented, tough, and passionate, he helped to establish our team's culture and played a vital role in our success over the years.

"Zach created so many memories that will live on forever, from setting numerous franchise and league records, to reaching across the end zone for the game-winning touchdown in our first-ever Super Bowl Championship. He will always be a member of the Eagles family, not only because of what he accomplished on the field, but also because of the wonderful person, dedicated leader, and exemplary role model that he was for nine seasons in Philadelphia. We wish Zach and [wife] Julie nothing but the best."

The Cardinals, top of the NFC West after a 5-0 start, welcomed Ertz as a "talented replacement" for Maxx Williams, who is out for the rest of the season with a knee injury.

The Green Bay Packers head into Week 6 on the back of a remarkable overtime victory over the Cincinnati Bengals last time out.

Mason Crosby was the hero with a match-winning field goal, though his successful punt came on the back of three misses, not to mention the Bengals' Evan McPherson twice clipping the post with efforts in both regulation time and overtime.

The win took the Packers to 4-1 for the season, and next up are old rivals the Chicago Bears on Sunday. 

Meanwhile, the Baltimore Ravens (also 4-1) will look to build on their Lamar Jackson-inspired comeback against the Indianapolis Colts on Monday by beating the similarly in-form Los Angeles Chargers, and the Arizona Cardinals will look to continue their perfect start to the season as they travel to Cleveland.

 

Green Bay Packers @ Chicago Bears

One of the fiercest rivalries in the NFL rears its head in Week 6, with Green Bay travelling to Chicago. The foes share 22 championship titles between them, and this divisional contest in the NFC North is sure to serve up a treat.

The Packers are 21-5 in regular-season games against the Bears since 2008, when Aaron Rodgers became Green Bay's starting quarterback - indeed, Rodgers has started 25 of those meetings and is 11-2 in the 13 games he has started against Chicago since 2014, throwing 33 touchdown passes and no interceptions in 11 wins. There are three other matchups in which one team has beaten the other 21 times since 2008: Baltimore over the Cleveland Browns (22-4) and the New England Patriots over the New York Jets (22-5) and the Buffalo Bills (21-5).

This is the Packers' first road game against a division rival this season. Green Bay won all three of their away games against NFC North rivals in each of the past two campaigns.

Chicago are 3-2 for the season, though they have a league-low 728 passing yards. The Saints, with 904, are the only other team below 1000. If the Bears are to get anything from this game, they may well rely on the defensive prowess of Khalil Mack, who led the team with seven tackles in Week 5's 20-6 win over the Las Vegas Raiders.

Rodgers will be looking to pick out Davante Adams, meanwhile. He caught 11 passes for 206 yards in the win in Cincinnati. It was the third time since 1997 that a Packers player had 200 or more receiving yards in one game. 

Los Angeles Chargers @ Baltimore Ravens

This will be the first meeting between the Chargers and Ravens since the 2018 Wild Card round – Los Angeles claiming a 23-17 win on that occasion.

The Ravens are 3-1 in the regular season at home against the Chargers, though the last three games have been decided by seven points total. Baltimore go into the game on the back of a brilliant comeback win over the Colts. They trailed by 19 points with less than one minute remaining in the third quarter but came back to win 31-25 in overtime - their largest second-half comeback victory in franchise history.

Quarterback Jackson threw for 335 of his 442 passing yards in the second half and overtime, while completing 90.6 per cent of his passes (29/32). Over the last 30 seasons, there have been 635 quarterbacks to attempt at least 30 passes in the second half/OT of a game – he is the only one with a completion percentage over 90 per cent.

Los Angeles QB Justin Herbert, meanwhile, accounted for five touchdowns (four passing, one rushing) along with 427 total yards in just his 20th career start in the Chargers' 47-42 win in Cleveland. For any quarterback in his first 20 career starts, Herbert ranks first in completions (535), second in pass yards (5912) and third in total touchdowns (50).

Arizona Cardinals @ Cleveland Browns

The Cardinals' dream start to the season continued with a 17-10 triumph over the San Francisco 49ers. Arizona is the only unbeaten team in the NFL. This is the fifth time the Cardinals, an original NFL franchise, have won their first five games but first time since moving from St. Louis in 1988.

Arizona have won their last four games against the Browns, dating back to 2007. Before this streak, they had never won more than two consecutive games versus Cleveland. The Browns lead the all-time series, 33 wins to 15, with three ties.

The Browns, however, have won their last six games against NFC teams, including wins against the Bears and Vikings this season. Cleveland’s last loss against an NFC opponent was to the Cardinals in Arizona in 2019 (38-24).

Cleveland's Nick Chubb has 4080 yards rushing in his 49-game NFL career, and will likely become the third active player who had at least 4000 rushing yards through his first 50 games in the NFL, joining Ezekiel Elliott (4881) and Le'Veon Bell (4225).

Elsewhere...

The Patriots have endured a difficult start for the season, going 2-3 through the opening five games. The 4-1 Cowboys are next up, though New England have history on their side, having won six straight games against Dallas, a run dating back to 1998.

London calls for the Miami Dolphins and Jacksonville Jaguars, as the Florida rivals go head-to-head at Tottenham Hotspur Stadium. The Jaguars' 37-19 loss at home to the Tennessee Titans last week extended their losing streak to 20 games. It is just the second 20-game losing streak in NFL history (the Tampa Bay Buccaneers lost 26 straight between 1976 and 1977).

It has been a difficult week for the Raiders, whose coach Jon Gruden resigned due to the emergence of offensive emails. Las Vegas take on the Denver Broncos, who they have more wins against than any other opponent in their history.

Cincinnati will look to bounce back from their defeat to the Packers when they take on Detroit. They have won six consecutive games against the Lions, going back to 1998, and a win on Sunday would see the Bengals equal a team record for the most successive victories against a single opponent, matching seven-game streaks against the Houston Oilers (1981- 1984) and the Browns (2014-2017).

Justin Herbert and the Los Angeles Chargers took another step in establishing themselves as NFL Super Bowl contenders as they pulled out a wild 47-42 victory over the Cleveland Browns.

The lead changed hands seven times as Herbert and Browns quarterback Baker Mayfield led their teams downfield almost at will, but the Chargers (4-1) scored last and the Browns (3-2) could not respond on Sunday.

Herbert continued building his MVP case as he went 26-of-43 passing for 398 yards and four touchdowns with no interceptions and ran for another score. 

The Chargers trailed 27-13 after a spectacular 52-yard touchdown run by Nick Chubb on the opening drive of the second half, but Herbert led them back to take a 28-27 lead and the teams exchanged touchdowns from there. 

Los Angeles thought they had tied the game when Herbert hit Austin Ekeler for a 19-yard touchdown with 3:15 to play but Tristan Vizcaino missed his second extra point of the game to leave the Chargers trailing by a point. 

The Browns went three and out on the next possession and Herbert led the Chargers to the three-yard line, where the Cleveland defence helped Ekeler cross the goal line on purpose with 1:31 to play so the Browns could get the ball back. 

But Mayfield could not finish the job, throwing three successive incompletions from the Cleveland 47-yard line to give the Chargers the ball and end the game. 

Murray, Cardinals remain unbeaten

The Arizona Cardinals improved to 5-0 and remain the only unbeaten team in the NFL after pulling out a 17-10 win against the San Francisco 49ers. 

Kyler Murray's explosive Arizona offence entered the game averaging 35 points per game but had to scrape out the win as they were out-gained 338 to 304 by Trey Lance and the 49ers (2-3). 

Murray completed 22 of 31 passes for 239 yards and a key nine-yard touchdown pass to DeAndre Hopkins with 5:13 to play that effectively put the game out of reach. 

Rookie quarterback Lance made his first start for San Francisco and completed just 15 of 29 passes for 192 yards with an interception, though he led all rushers in the game with 89 yards on the ground. 

Cowboys run away from battered Giants

The Dallas Cowboys took advantage of injuries to the New York Giants' two most important players on offence, rolling to a 44-20 home victory. 

The Giants lost quarterback Daniel Jones to a concussion and running back Saquon Barkley to an ankle injury and were outscored 27-7 after Graham Gano hit a field goal on the first drive of the second half. 

Dak Prescott completed 22 of 32 passes for 302 yards and three touchdowns for Dallas, while Ezekiel Elliott ran for 110 yards and a score. 

Star tight end George Kittle has been placed on injured reserve by the San Francisco 49ers.

On the same day he turned 28, the Niners confirmed their two-time All-Pro had been subject to the roster move due to an ongoing calf problem.

The decision means Kittle must miss at least three matches, including the upcoming NFC West divisional matchup at the undefeated Arizona Cardinals, a game for which he had initially been listed as doubtful.

San Francisco are already without quarterback Jimmy Garoppolo, who also has a calf problem, against the Cardinals, meaning rookie Trey Lance will start.

The team, who are 2-2 after losing two straight games, will hope Kittle is good to go again by Week 8 when they meet the Cardinals once more.

Kittle has struggled with his nagging injury for much of the 2021 season and has made just 19 catches for 227 yards, as he waits to score his first touchdown of the year.

He was restricted to just eight regular season games last year after suffering a broken foot.

Prior to those injury problems, Kittle had been utterly dominant in 2018 and 2019, helping the Niners to the Super Bowl in that period with 2,430 yards and 10 receiving TDs across 30 regular season games.

Kittle was a fifth-round draft pick ahead of the 2017 season.

Trey Lance will make his first start for the San Francisco 49ers against the Arizona Cardinals on Sunday.

Head coach Kyle Shanahan confirmed Lance would get the start after Jimmy Garoppolo again missed practice on Friday.

Garoppolo suffered a calf contusion during the first offensive series in San Francisco's 28-21 loss to the Seattle Seahawks last week.

He played the rest of the first half but was replaced by rookie third overall pick Lance for the second half.

Lance completed nine of his 18 passes for 157 yards and two touchdowns while rushing for 41 yards on seven carries.

San Francisco traded three first-round selections to move up from the 12th pick to the third pick in this year's draft for the right to take Lance and make him their quarterback of the future.

Sunday will provide his first opportunity to prove the 2-2 Niners were right to make that move across the course of a full game.

Inexperienced even at the college level, Lance played only one full season as a starter for North Dakota State in 2019, which saw him account for 42 total touchdowns and zero interceptions, with the COVID-19 pandemic limiting him to a one-game exhibition in 2020.

But Lance is undaunted by the challenge of stepping up to start at the highest level this early in his career against an undefeated Cardinals team.

"I feel very prepared. I really do. And I think that's a credit to the coaching staff and the guys around me," Lance told a media conference. 

"Those guys have made me feel very confident this week, and I feel confident in myself, just as I did going into the Seattle game, and just as I did every other week before this."

Lance is unlikely to have one of the 49ers' top offensive weapons available, with tight end George Kittle doubtful with a calf injury. Rookie running back Elijah Mitchell is set to return from a shoulder injury, meaning the running game will be almost exclusively in the hands of three rookies in the form of Lance, Mitchell and third-round pick Trey Sermon.

The Kansas City Chiefs will be out to burst the in-form Buffalo Bills' bubble when they meet in a standout NFL Week 5 showdown.

Buffalo stretched their winning run to three matches with a 40-0 rout of the Houston Texans last Sunday.

Week 4 was also one to remember for the Chiefs and particularly Andy Reid, who became the first coach in NFL history to win 100 games with two teams thanks to a 42-30 defeat of his former employers the Philadelphia Eagles.

As the only team with a perfect record, the Arizona Cardinals will look to make it 5-0 at the expense of the San Francisco 49ers.

Stats Perform previews the pick of the action in the next round of matches and the best of the rest.

 

Buffalo Bills @ Kansas City Chiefs

The Bills are sitting pretty at the top of the AFC East at 3-1, but they have lost five of their past six meetings against the Chiefs.

Buffalo will be on a revenge mission after they were beaten 38-24 by Kansas City in the AFC Championship Game last season, the largest margin of victory for the Chiefs in those five triumphs.

The Bills' thrashing of the Texans was the second time this season they have kept an opponent scoreless, having also done so against the Miami Dolphins in Week 2.

Reid's side prop up the AFC West with a 2-2 record, but their 18 touchdowns is more than any in the NFL and Josh Gordon will be hoping to add to that tally if he makes his debut.

San Francisco 49ers @ Arizona Cardinals

The Cardinals' dream start to the season continued with a 37-20 victory over the Los Angeles Rams in Week 4, taking them to 4-0 for only the second time since moving to Arizona nine years after they previously won their opening four games.

If recent history is anything to go by, there will not be much in their showdown this weekend, as four of the past five meetings between the two sides have been decided by only three points.

The 2-2 49ers travel to State Farm Stadium having come out on top in four of their previous four meetings, having lost their eight clashes beforehand.

Deebo Samuel caught a 76-yard touchdown pass in San Francisco's 28-21 loss to Seattle Seahawks in Week 4, making him the fourth 49ers wide receiver to have multiple receiving touchdowns of 75-plus yards in a single season – joining Torrey Smith, John Taylor, and Jerry Rice.

Cleveland Browns @ Los Angeles Chargers 

The Browns and the Chargers have made promising starts to the season and both come into the game on the back of wins that took them to 3-1.

Cleveland have not beaten the Chargers on the road since back in 1991, losing five on the spin since then – a run that is tied for their third-longest active road losing streak against an opponent (lost 17 straight in Pittsburgh and six straight at New England).

The past two games mark the first time the Browns have allowed seven points or fewer back-to-back since September 10-17, 1995. They have done so in three straight games only once in franchise history (in 1976).

Nick Chubb (388) and Kareem Hunt (355) are the second pair of running backs in the last 30 years to have 350+ scrimmage yards apiece over their team's first four games of a season. The other was the Chargers' Melvin Gordon III and Austin Ekeler in 2018. 

Elsewhere

Tom Brady broke Drew Brees' NFL passing yards record in the Tampa Bay Buccaneers' win over his former team the New England Patriots in Week 4 and could inflict more misery on the Dolphins this weekend. The legendary quarterback has thrown 67 touchdowns against Miami the third-most by a player against any opponent in the Super Bowl era (Dan Marino – 72 v. the New York Jets, Brady – 70 v. the Bills). 

The Green Bay Packers head to Cincinnati to do battle with the Bengals, who they beat 27-24 in their last encounter in 2017. That snapped a three-game winning streak by the Bengals in the series. The Packers' last win in Cincinnati came in Week 3 of the 1998 season.

Urban Meyer has come under fire for his night out after the Jacksonville Jaguars suffered a fourth loss from four last week and he really needs a win when the Florida team host the Tennessee Titans. Tennessee are 7-1 versus the Jaguars since 2017.

NFC East leaders the Dallas Cowboys will go in search of a fifth consecutive home win over the New York Giants.

The Arizona Cardinals are the last undefeated team left standing in the NFL after the Las Vegas Raiders were beaten on Monday.

There were five unbeaten franchises heading into Week 4 of the regular season, though one '0' was bound to go when the Cardinals travelled to the Los Angeles Rams, who had beaten reigning champions Tampa Bay in their previous outing.

However, Aaron Donald and the rest of the Rams defense could not slow down Arizona, who emphatically triumphed 37-20 on the road to take charge of the NFC West.

As for the others, the Denver Broncos went down at home to the Baltimore Ravens, while the Carolina Panthers lost in Dallas to the Cowboys.

With the Raiders unable to rally in the second half to overcome the Los Angeles Chargers, the Cardinals stand alone at 4-0 – and that is not their only impressive achievement.

They are the outright leaders in terms of winning percentage (1.000), but also total offense (440.5 yards) and scoring offense (35.0 points per game) as well. No team has topped all three categories through four weeks of a campaign since the Cleveland Browns in 1953.

However, head coach Kliff Kingsbury was clearly not getting too carried away by his team's start, as he made clear in the post-match media conference. Asked what he planned to do to celebrate beating the Rams, he replied: "Not so much. I'll watch Ted Lasso tonight and go to bed."

The play of Kyler Murray has been a key factor in the unbeaten run, the quarterback throwing for 1,273 yards, nine touchdowns and four interceptions. He has also ran for three scores, while his 76.1 completion percentage is the best in the NFL.

Murray's performances have not only led to Arizona winning four straight, but also pushed him to the front of the MVP race, albeit it is still only the early stages of the season.

The Cardinals are bidding to make the playoffs for the first time since 2015. They started the previous year with a 5-2 record, only to fall away after their bye week, losing six of their final nine games.

They face another stern test in Week 5, as they host divisional rivals the San Francisco 49ers (2-2).

Kyler Murray said the Arizona Cardinals are riding a wave of confidence after emerging as the NFC's lone unbeaten team following their win against the Los Angeles Rams.

The Cardinals improved to 4-0 for the NFL season thanks to a Murray-inspired 37-20 victory over the Rams in the battle of two undefeated franchises on Sunday.

Arizona quarterback Murray passed for 268 yards and two touchdowns, while running for 39 more yards as the Cardinals dismantled the Rams at Sofi Stadium, ending a run of eight straight defeats against a Sean McVay-coached team.

Murray became just the third player in the Super Bowl era with a 4-0 record, completion percentage of 75 or better and 1,200-plus passing yards in his team's first four games of a season, after Hall of Famer Peyton Manning and Seattle Seahawks star Russell Wilson.

"I was pretty confident coming into this game with the game plan we had, the week of practice we put together, probably the best game plan that I think personally that we've had since I've been in the league," Rams star Murray told reporters.

"With that, being confident in all the guys, this team, I was just confident in going out there and letting it ride. The guys did the same and I can't be more proud of them."

Murray added: "Not really too worried about what other people think. I think the guys in the locker room understand what we're doing, what we're capable of and where we can take it."

The Cardinals have not reached the playoffs since losing to the Carolina Panthers in the 2015 NFC Championship Game.

But, Arizona are attracting plenty of attention this season – the Cardinals have scored at least 30 points and had at least 400 yards of offense in every game.

"Not a statement," Cardinals head coach Kliff Kingsbury said. "We wanted to get a week better. Division games are important. We've got to continue to play physical football and clean some stuff up."

Page 4 of 6
© 2022 SportsMaxTV All Rights Reserved.