Arizona Cardinals quarterback Kyler Murray is set to miss a minimum of five days of his side's training camp after testing positive to COVID-19.

Cardinals coach Kliff Kingsbury confirmed the news on Monday, revealing Murray's symptoms were "minor".

The Arizona quarterback, who had missed practice on Saturday due to a sore wrist, is the only Cardinals player to test positive currently.

The news comes in light of a busy few weeks for Murray, who agreed terms on a bumper five-year extension with the Cardinals last month. The deal made Murray the NFL's second-highest paid player in terms of average annual salary.

Murray stayed in the spotlight after an "independent study" clause was inserted into the contract, mandating four hours of study each game week, which was later removed.

Murray, a former standout baseball player at Oklahoma as well who was taken ninth overall in the 2018 MLB draft, led the Cardinals to their first playoff appearance in six years with an 11-6 finish to the 2021 season.

The 24-year-old began last season as an MVP candidate as Arizona got off to a 7-0 start, with Murray producing a 116.8 passer rating with a 73.5 per cent completion rate and 17 touchdown passes during that stretch.

However, his play dropped off over the season's second half, as Arizona went 2-5 over his next seven starts, and he struggled with a no-touchdown, two-interception performance in the Cardinals' 34-11 loss to the Los Angeles Rams in the opening round of the playoffs.

Kansas City Chiefs quarterback Patrick Mahomes addressed the infamous "study clause" in Kyler Murray's contract on Friday, saying it is "weird" how black quarterbacks are criticised in the NFL. 

Murray made headlines earlier this week when it was revealed his five-year, $230.5million contract extension with the Arizona Cardinals contained a clause requiring him to independently watch at least four hours of game film per week during the season. 

After the report surfaced, Murray made an impassioned defense of his work ethic, and the Cardinals announced on Thursday that the addendum was removed from his contract. 

"Obviously, the black quarterback has had to battle to be in this position that we are to have this many guys in the league playing," Mahomes said after a camp practice.

"Every day, we're proving that we should have been playing the whole time. 

"We've got guys that can think just as well as they can use their athleticism. It's always weird when you see guys like me, Lamar [Jackson], Kyler kind of get that on them when other guys don't.

"But at the same time, we're going out there to prove ourselves every day to show we can be some of the best quarterbacks in the league."

However, Mahomes noted all NFL quarterbacks feel pressure to prove their worth.

"You always feel like you have more to prove," he said. "I promise Tom Brady is feeling like he has more to prove.

"That comes with any sport, any competitor. If you're not getting better, you're getting worse. They build you up to tear you down. You've got to kind of know that. 

"For me, it's all about how I can make myself better, not what other people say. How can I make myself better so that we go out there and play football games?

"At the end of the day, nothing matters until you're on that football field playing, and that's where you get to prove who you are every single day."

The Arizona Cardinals have removed a controversial "independent study" clause from Kyler Murray's new contract after the quarterback gave an impassioned response to questions about his preparation and work ethic.

NFL.com reported the addendum to the five-year, $230.5million extension earlier this week.

The clause stipulated that the two-time Pro Bowler must watch a minimum of four hours of game film on his own every week during the season over the life of the deal, and the Cardinals could void the contract if Murray did not meet the terms of the agreement.

"After seeing the distraction it created, we removed the addendum from the contract," the Cardinals have now said in a statement. "It was clearly perceived in ways that were never intended.

"Our confidence in Kyler Murray is as high as it's ever been and nothing demonstrates our belief in his ability to lead this team more than the commitment reflected in this contract."

The public revelation of the clause prompted the usually reserved Murray to call an unscheduled press conference on Thursday in which the 2019 number one overall pick lashed out against suggestions he was not properly preparing for his duties.

"I refuse to let my work ethic, my preparation be in question," Murray stated. "I've put in incomprehensible amount of time and blood, sweat and tears and work into what I do.

"To those of you out there who believe that I'd be standing here today in front of you all without having a work ethic and without preparing – I'm honoured that you think that, but it doesn't exist. It's not possible.

"To think that I can accomplish everything that I've accomplished in my career and not be a student of the game and not have that passion, not take this seriously is almost... it's disrespectful and it's almost a joke."

Murray agreed to the extension, which will make him the NFL's second-highest-paid player in terms of average annual salary behind only two-time reigning league MVP Aaron Rodgers, last week. The contract contains $160m in guarantees and will run from 2024 through 2028. 

The 2018 Heisman Trophy winner is coming off his best season in which he finished second in the NFL in completion percentage (69.2) and posted a career-high 100.6 passer rating while helping the Cardinals reach the playoffs for the first time since 2015.

Murray's play dropped off during the second half of the year, however, and he also struggled with a no-touchdown, two-interception performance in the Cardinals' 34-11 loss to the Los Angeles Rams in the opening round of the playoffs. 

Arizona began last season 7-0 but lost five of the 24-year-old's next seven starts, with Murray producing an 86.5 passer rating during that stretch after recording a 116.8 rating over the first seven games.

With his work ethic and preparation methods recently called into question, Arizona Cardinals quarterback Kyler Murray called an impromptu press conference on Thursday to answer his critics. 

The former Heisman Trophy winner and two-time Pro Bowl honoree bristled at the suggestion he could achieve what he has in both his college and professional career without taking his job seriously.

Murray delivered a sharp response to the recent criticism he has received after a report this week stated his new $230million contract contained a clause that mandated four hours of independent film study per week during the season.  

"To think that I can accomplish everything that I've accomplished in my career and not be a student of the game and not have that passion, not take this seriously, is almost – it's disrespectful and it's almost a joke," Murray said.

"I'm honestly flattered that you all think at my size I can go out there and not prepare for the game," the 5-foot-10, 207-pound quarterback said. "This game's too hard. To play the position that I play in this league, it's too hard. 

"I'm not 6-7, 230 [pounds]. I don't throw the ball 85 yards. I'm already behind the eight-ball and I can't afford to take any shortcuts, no pun intended."

According to NFL.com, Murray can be found to be in breach of his new deal should he not fulfil the obligations of the "independent study" addendum.

The 2019 No. 1 overall pick last week agreed to the five-year extension, which will make him the NFL's second-highest paid player in terms of average annual salary.

Murray did not directly answer questions about specific parts of the contract, though he did make a statement about his film study habits. 

"There's multiple ways to watch film," he said. "There's many different ways to process that game; there's many different ways quarterbacks learn the game and break the game down.

"Of course, I watch film by myself. That's a given. That doesn't even need to be said. But I do enjoy and love the process of watching the game with my guys, the quarterbacks, the coaches.  

"I refuse to let my work ethic, my preparation, be in question. I've put in incomprehensible amount of time and blood, sweat and tears and work into what I do.

"To those of you out there who believe that I'd be standing here today in front of you all without having a work ethic and without preparing, I'm honoured that you think that, but it doesn't exist. It's not possible.” 

Murray, a former standout baseball player at Oklahoma as well who was taken ninth overall in the 2018 MLB draft, led the Cardinals to their first playoff appearance in six years with an 11-6 finish to the 2021 season. 

The 24-year-old began last season as an MVP candidate as Arizona got off to a 7-0 start, with Murray producing a 116.8 passer rating with a 73.5 per cent completion rate and 17 touchdown passes during that stretch. 

However, his play dropped off over the season's second half. Murray's passer rating dipped to 86.5 as Arizona went 2-5 over his next seven starts, and he struggled with a no-touchdown, two-interception performance in the Cardinals' 34-11 loss to the Los Angeles Rams in the opening round of the playoffs. 

Kyler Murray had no desire to continue his NFL career anywhere other than with the Arizona Cardinals, the quarterback said after signing a five-year, $230.5million contract extension.

Murray and the Cardinals finally reached agreement on a deal that contains $160m guaranteed on Thursday, rewarding him for three seasons of largely stellar play and Arizona's first playoff appearance since 2015 last season.

Negotiations between the two franchises had not always appeared to be harmonious, particularly in late February when Murray and his agent Erik Burkhardt released a statement seemingly urging the Cardinals to prioritise signing the former to a long-term deal rather than simply talking about it.

But, with the saga behind them, Murray is now fully focused on his ultimate goal in the NFL.

"My job is to fulfill my promise and bring a championship here. There's no question about it," Murray said.

"There's no other place that I wanted to be this whole time. And I mean that."

Murray prompted a heated reaction on social media when he deleted all photos relating to the Cardinals from his Instagram account following his appearance in the Pro Bowl.

"All the social media stuff and all that, that's going to happen regardless," Murray added. "Play good, they love you. Play bad, they hate you.

"It is what it is. That's just this day and age. You've got to have tough skin. So, I've grown up in it. So, it's nothing new."

Before being selected as the first overall pick by Arizona in 2019, Murray was picked ninth overall in the 2018 MLB Draft by the Oakland Athletics and signed a contract with the A's.

Asked if this extension ends any prospect of Murray eventually switching to baseball, Cardinals general manager Steve Keim interjected and could not resist a dig at the A's, who have parted with a host of their stars in recent times and have the second-lowest payroll in MLB at $48.5m.

"Did you guys see the payroll of the Oakland A's versus this contract?" Keim replied. "Enough said."

The Arizona Cardinals have agreed to terms with quarterback Kyler Murray on a multi-year extension that will reportedly make him among the NFL's highest-paid players.

Terms of the agreement were not disclosed but ESPN reports the deal to be a five-year, $230.5million pact with $160m guaranteed, that will run through the 2028 season.

Murray, the No.1 overall pick of the 2019 draft and the NFL Offensive Rookie of the Year that season, has two years remaining on his original contract.

The deal is slightly higher than the five-year, $230m extension the Cleveland Browns gave Deshaun Watson in March, though Watson's contract is fully guaranteed.

Murray's $46.1m annual average salary over the duration of the extension is the second highest in the NFL, behind only two-time reigning league MVP Aaron Rodgers' $50.3m.

Arizona also avoid a potential distraction involving their quarterback's future entering training camp.

ESPN reported in February that Murray was frustrated over a lack of progress in extension talks and the criticism he received following the team's playoff loss to the eventual champions Los Angeles Rams.

Murray did not attend voluntary offseason workouts but did take part in the Cardinals' mandatory minicamp last month.

The 2018 Heisman Trophy winner has started all but two of Arizona's games since entering the NFL and has helped the Cardinals increase their win total in each of his three seasons, capped by an 11-6 finish in 2021 and the franchise's first playoff appearance in six years.

Murray began last season as an early MVP candidate after leading the Cardinals to a 7-0 start, though his and the team's play dropped off in the second half with a nagging ankle injury a factor in his struggles.

The 24-year-old produced a 116.8 passer rating with a 73.5 per cent completion percentage and 17 touchdown passes during the seven-game winning streak.

Murray's rating dipped to 86.5 as Arizona went 2-5 in his next seven starts, and he threw just seven touchdown passes over that span with a significantly lower completion rate of 65.5 per cent.

Murray's rough stretch continued into the postseason as he completed just 19 of 34 passes for 137 yards with no touchdowns and two interceptions in the Cardinals' 34-11 opening-round loss to the Rams.

The former University of Oklahoma star still earned a second consecutive Pro Bowl nod after finishing second in the NFL in completion percentage (69.2 per cent) and posting a career-high 100.6 passer rating

Arizona Cardinals head coach Kliff Kingsbury says he is "praying" quarterback Kyler Murray will have signed his new contract before training camp begins next month.

Earlier in the offseason, Murray removed references to the Cardinals on his Instagram account before his agent Erik Burkhardt issued a statement calling for the QB, who is entering his fourth NFL campaign, to be shown "a real commitment" by the franchise.

There have been reports suggesting Murray will not attend training camp under his current deal, which runs through the 2023 season, as he seeks a lucrative extension.

Kingsbury was asked about his QB's contract status when he faced reporters after the first day of Arizona's minicamp, which Murray has reported for.

"I'm praying before training camp," Kingsbury said about when the contract could be resolved.

"I just want him there day one of training camp. Personally - I'm being selfish here – I would love for him to be there the first day.

"I'm not sure [if he will report to training camp without a new deal] - that would be a Kyler question."

"We're about to make him, I'm sure, the highest-paid player in this franchise's history and so he understands what comes with that," added Kingsbury, per ESPN.

"The guys know what he can be at his best, and anytime we can get the whole band out there, things pick up.

"He is the leader of this franchise. [General Manager] Steve [Keim], Michael [Bidwill], myself, we understand what he can be and where we want to take this thing with him as our leader. 

"It will be great for this organisation when this is wrapped up."

In the 2021 season, Murray threw for 3,787 yards with 24 touchdown passes and added five rushing TDs, while he had the second-highest pass completion rate in the NFL of 69.2 per cent.

Murray was the first overall pick in the 2019 NFL Draft and an 11-6 record last season was the Cardinals' best for six years.

They lost to divisional rivals the Los Angeles Rams, who went on to win the Super Bowl, in the Wild Card round of the playoffs.

Arizona Cardinals cornerback Jeff Gladney has died after being involved in a car accident in the early hours of Monday morning.

The Dallas County Sheriff's Office announced that at 2:28am, first-responders attended a scene where two cars collided.

One other person died in the crash. The second victim has not been identified as the incident remains under investigation.

The Cardinals confirmed Gladney's death in a brief statement.

"We are devastated to learn of Jeff Gladney's passing. Our hearts go out to his family, friends and all who are mourning this tremendous loss," the statement read.

Gladney, 25, was a first-round pick in the 2020 NFL Draft by the Minnesota Vikings after a glittering college career at TCU, where he became close friends with Philadelphia Eagles wide receiver Jalen Reagor.

Responding to the news, Reagor tweeted out: "Lost my brother, my best friend, my right hand man… ain't too much more I can take man damn! R.I.P Jeff Gladney, brother watch over me please."

J.J. Watt was one of several of Gladney's Cardinals teammates to also pay their respects, saying: "Horrifying news to hear this morning. Just tragic. Rest in peace Jeff."

Gladney's former team, the Vikings, also offered their condolences.

"We are saddened by the tragic death of former Viking Jeff Gladney," the franchise said. "Our hearts go out to his family and friends, as well as the Arizona Cardinals organisation and Jeff’s current and former teammates and coaches who are mourning his life lost much too soon."

Larry Fitzgerald does not believe DeAndre Hopkins' PED suspension will have any impact on his long-term legacy.

All-Pro wide receiver Hopkins was this month suspended for the first six games of the 2022 campaign for violating the NFL's policy on performance-enhancing drugs.

The news served as a substantial blow to the Arizona Cardinals and their hopes of success in the coming season.

But Cardinals legend and former team-mate Fitzgerald rejected talk of the ban tarnishing Hopkins' reputation.

"I don't think so," Fitzgerald said when asked by TMZ if he thought the suspension would taint Hopkins' legacy.

"He'll still be a Hall of Famer. He's talented. He'll work through it.

"It's just some adversity and, you know, he's a tough guy, resourceful, and he'll work his way through it."

The Cardinals may have a tougher time working their way through his 2022 absence.

With Hopkins on the field last year in the regular season, they went 8-2, averaging 30.2 points per game. In the seven games he missed through injury, the Cardinals were 3-4, scoring 21 points per game.

They start their 2022 campaign with an extremely difficult assignment, hosting a Kansas City Chiefs team that has reached the AFC Championship Game in each of the last four seasons.

The Arizona Cardinals and San Francisco 49ers will contest the NFL's first game in Mexico City since 2019.

Estadio Azteca hosted a game every year from 2016 to 2019, save for the 2018 season when the Rams' clash with the Kansas City Chiefs was moved back to Los Angeles because of poor field conditions.

But the coronavirus pandemic meant there were no International Series games in 2020, with Mexico City left off the schedule for 2021.

It was confirmed in February that the Cardinals would host a game in Mexico City and it was announced on Wednesday that they will face their NFC West rivals on November 21.

Both the Cardinals and the Niners made the playoffs in 2021, Arizona losing in the Wild Card round to the eventual Super Bowl-champion Rams and San Francisco beaten by the same opposition in the NFC Championship Game.

The Cardinals and the Niners met in the first NFL game to be played in Mexico back in 2005, with Arizona claiming a 31-14 victory.

The Green Bay Packers' first regular-season game outside of the United States will see them face the New York Giants.

It was confirmed in February that reigning MVP Aaron Rodgers and Co. would play in London for the first time.

That game will take place at Tottenham Hotspur Stadium on October 9, with the Packers taking on a historic NFC foe in Week 5.

The Giants won the inaugural London game at Wembley in 2007, defeating the Miami Dolphins, and beat the Los Angeles Rams at Twickenham in 2016.

Tottenham will also play host to a clash between the Minnesota Vikings and New Orleans Saints on October 2.

Both the Vikings and Saints have played and won twice in London, New Orleans shutting out the Miami Dolphins on their last appearance in 2017.

The sole Wembley game will see new Denver Broncos quarterback Russell Wilson face Trevor Lawrence and the Jacksonville Jaguars at England's national stadium on October 30.

Arizona Cardinals wide receiver DeAndre Hopkins is to be suspended for six games by the NFL for violation of the league's performance-enhancing drug policy, according to reports.

The 29-year-old required MCL surgery after suffering a knee injury in December's 30-23 defeat to the Los Angeles Rams, missing the remainder of the 2021 campaign, including the Wild Card playoff loss to the Rams.

According to ESPN's Adam Schefter, the Cardinals will be without Hopkins for the opening six games of the season due to his suspension, which is final after he withdrew his appeal.

The Cardinals traded on draft day for another wide receiver, Marquise Brown, having lost Christian Kirk after the 25-year-old signed a $72million contract with the Jacksonville Jaguars.

In the 10 games he did play in last season, Hopkins – a three-time first-team All-Pro and five-time Pro Bowl selection – managed 42 receptions for a total of 572 yards, with eight touchdowns to his name.

In the 2020 season, his first with Arizona after being traded by the Houston Texans, he recorded 1,407 yards from 115 receptions, and six TDs.

New Arizona Cardinals wide receiver Marquise Brown has confirmed he requested his trade away from the Baltimore Ravens.

And the former Oklahoma pass catcher, who is to be reunited with Kyler Murray, says he told Lamar Jackson the Ravens' run-first offensive system "wasn't for me" more than a year ago.

In one of two significant receiver trades on the first day of the 2022 NFL Draft, the Cardinals parted with the 23rd overall pick in return for Brown and a third-round selection.

Having already secured perhaps the best player in the draft in ultra-versatile safety Kyle Hamilton, the Ravens used their additional first-round pick to bolster their offensive line in front of quarterback Jackson with center Tyler Linderbaum.

Jackson's Twitter activity suggested he was unhappy with the Ravens' business, frustrated by the loss of the wide receiver he has looked to more than any other in his NFL career to date (256 targets, 164 receptions, 20 touchdowns).

The former NFL MVP posted a series of messages, including sharing a post from Brown in which he said to his former QB: "Wish I coulda played with my brotha forever but ima see you at the top."

However, speaking to media on Friday, Brown revealed he was the driving force behind the trade, and his desire to move on could have come as no surprise to Jackson.

"It was just [about] my happiness," he said. "I talked to Lamar about it after my second year, then after my third year leading up to the end of the season.

"He wasn't playing, but I let him know again: I can't do it.

"It's not really on Lamar; I love Lamar. It's just the system wasn't for me, personally. I love all my team-mates, I love the guys, but it was just something I had to think about for myself.

"The Ravens and I both handled it the right way. I didn't go out and make anything public; I just kept it in-house, kept working, and it all worked out."

In the 2019 and 2020 seasons, Jackson's first two as a full-time starter, the Ravens ran on 56.0 per cent and 55.9 per cent of their plays respectively, leading the league in this regard.

Since entering the NFL in 2018, Jackson has recorded 3,673 rushing yards – by far the most among QBs and the seventh-most of all players.

Murray (1,786 rushing yards just since 2019) is third among QBs over that period, but Brown already knows he can effectively link up with the Cardinals star.

In 2018, at Oklahoma, Murray's 4,361 passing yards and 42 passing TDs led the Big 12, with Brown his top receiver with 1,318 receiving yards and 10 receiving TDs.

Murray wrote on Twitter following Brown's trade: "Let's run it back! Hollywood to the desert... Y'all welcome my boy!"

Marquise Brown is back with Kyler Murray after he was traded from the Baltimore Ravens to the Arizona Cardinals.

A first-round pick of the Ravens in 2019, Brown played with Murray during their college days at Oklahoma.

They will now look to re-establish their rapport after the Ravens sent Brown and a third-round pick (100th overall) to acquire Arizona's 23rd overall selection in the first round.

News of the trade came shortly after the Ravens used the 14th overall selection on safety Kyle Hamilton, regarded by some as the best player in the draft at any position.

Brown caught 91 passes for 1,008 yards in 2021, the first 1,000-yard season of his pro career.

His 21 receiving touchdowns since 2019 are the 11th-most among wide receivers during that span.

The ultra-versatile Hamilton, who can play as a deep safety, in the box and in the slot, registered eight interceptions between 2019 and 2021, the fifth-most among FBS safeties during that period.