After no little drama so far in the NFL, the action continues in Week 5 with another Sunday crammed full of appetising games.
Following a thriller between the Minnesota Vikings and the New Orleans Saints in London last week, England's capital plays host to the latest international series matchup as the New York Giants face the Green Bay Packers at Tottenham Hotspur Stadium.
Elsewhere, pre-season Super Bowl favourites the Buffalo Bills welcome the Pittsburgh Steelers, while the Philadelphia Eagles look to continue their winning streak on the road against the Arizona Cardinals.
With all that and more on offer, Stats Perform has delved into Opta data to preview this weekend's contests.
New York Giants (3-1) @ Green Bay Packers (3-1)
The Giants head to London on the back of a 20-12 victory against the Chicago Bears, where they did not have a single receiver with 20 or more receiving yards for the second time in six games, stretching back to last season. Prior to that, the Giants had one such instance in their previous 231 outings.
Last week, Aaron Rodgers went 21-for-35 (60.0 per cent) in the Packers' 27-24 overtime win against the New England Patriots, which tied the Tennessee Titans for the most overtime wins since 2017 (six).
In that game, Rashan Gary had two sacks and boasts at least one sack in all four games this season. No Packers player has recorded at least one sack in the team's first five matches of a campaign, since sacks became an official statistic in 1982.
Philadelphia Eagles (4-0) @ Arizona Cardinals (2-2)
The Eagles head to Arizona as the only undefeated side remaining in the 2022 season, but they have lost four straight road games against the Cardinals, coming as part of a 3-10 record since 1993 – their last win in Arizona coming in 2001.
Philadelphia maintained their winning streak against the Jaguars after fighting back from a 14-0 deficit, their first win when trailing by at least 14 points after the first quarter since 2014, also against the Jaguars, while their last such win prior to that was against the Jets in 1993.
Cardinals QB Kyler Murray threw two touchdowns and ran for another last week, tying Daunte Culpepper as the second-fastest quarterback to reach 75 passing TDs and 20 rushing career TDs, doing so in 50 games. Only Josh Allen (48 games) has been quicker to that total.
This season, the Cardinals have outscored their opponents 49-13 in the fourth quarter, boasting the best differential (+36) in that regard, while the Eagles are -20 this season in the fourth (9-29), ranking 27th in the league.
Pittsburgh Steelers (1-3) @ Buffalo Bills (3-1)
The Steelers boast a stellar overall record against the Bills, winning seven of the last nine matchups. However, they are 1-2 in games against Josh Allen, who has been responsible for at least one touchdown in his last 18 consecutive home games, tying Jim Kelly for the franchise record.
Sunday's game will mark Kenny Pickett's first career start, having thrown three interceptions in the second half against the New York Jets last week, making him the first Steelers debutant to throw three interceptions since Terry Hanratty in 1969.
He faces a challenge to get the Steelers' offense ticking, Pittsburgh having gained 1,115 total yards through the first four weeks of the season, the team's lowest tally since the 2010 season (1,078 yards).
Stefon Diggs is the man to watch for the Bills, boasting 406 receiving yards this season – 253 more than his closest teammate in the rankings (Isaiah McKenzie, 153), which is the largest such gap in an NFL team this season.
Elsewhere…
The Chicago Bears head to Minnesota to face the Vikings and rank last in the NFL for net passing yards, with 390 so far, some 168 fewer than the Giants with the second-lowest total (558). The Bears are the first team with fewer than 400 net passing yards in the first four games of a season since 2005.
Los Angeles Chargers quarterback Justin Herbert is looking to enhance his touchdown record on the road against the Cleveland Browns, having thrown at least one TD pass in 35 different games since making his debut in Week 2 of the 2020 season – tying him with Kirk Cousins for the most games with a TD pass over the last three seasons.
The Houston Texans travel to face the Jacksonville Jaguars on the back of eight straight wins against their opponents, which stands as Houston's longest streak against any opponent all-time. Houston have yet to post a win this season, however.
The Detroit Lions have set an NFL record already in this campaign, becoming the first side to score 140 or more points and concede 140 or more points across the first four games of a season. They travel to the New England Patriots.