Los Angeles Rams superstar Aaron Donald will likely miss the rest of the season due to injury, coach Sean McVay revealed on Friday.

The star defensive tackle has been absent for the Rams' last two NFL games after sustaining an ankle injury in the 26-10 loss to the Kansas City Chiefs on November 27.

McVay's men are already out of postseason contention at 4-10 following injury problems surrounding Matthew Stafford and Cooper Kupp and a host of other players.

Donald will remain sidelined along with that pair for Sunday's clash with the visiting Denver Broncos and McVay does not expect the 31-year-old to feature again this season for the reigning Super Bowl champions.

"Probably not," McVay responded when asked if Donald would feature again with three games left of the Rams' campaign.

"I just think, 'Will he be fully cleared to be Aaron Donald?'. And if he is, talk to him and see. But if not, we'll err on the side of being smart with him.

"But obviously, he's a guy that has certainly earned the right where you talk to him. But he's not cleared yet and I don't know that I see that changing in the next couple of weeks."

If Donald does not return, he will end 2022 with 49 tackles, five sacks, 10 tackles for loss and one forced fumble from his 11 games.

The three-time Defensive Player of the Year was named to a ninth straight Pro Bowl on Monday.