The Kansas City Chiefs and Baltimore Ravens both improved to 2-0 in the NFL but in contrasting fashion on Sunday.
Reigning Super Bowl champions the Chiefs needed overtime to see off the Los Angeles Chargers 23-20 in Week 2.
Lamar Jackson and the Ravens powered past the Houston Texans 33-16 on the road.
Meanwhile, Kyler Murray dazzled for the high-flying Arizona Cardinals and Russell Wilson sparked the Seattle Seahawks.
MAHOMES' CHIEFS OUTLAST CHARGERS
Patrick Mahomes and the Chiefs stayed perfect thanks to Harrison Butker's 58-yard field goal with less than two minutes remaining in OT.
Butker drilled three field goals for the day as he tied a Chiefs record for distance, while becoming the second kicker in NFL history to make a pair of 58-yard kicks in the same game.
It completed a rally for the Chiefs, who overturned a 17-6 deficit in the third quarter to survive an impressive NFL debut by Chargers rookie Justin Herbert.
Herbert threw 311 yards to become the ninth player since the merger to top 300 in his first game. He was 22 of 33 for a touchdown and interception.
As for former MVP and last season's Super Bowl MVP Mahomes, the Chiefs quarterback finished 27 of 47 for 302 passing yards and two touchdowns and rushed for 54 yards.
RAVENS PRESERVE UNBEATEN RUN
The Ravens overcame a slow start to extend their regular-season winning streak to 14 games – the longest run since the Carolina Panthers reeled off 18 successive victories in 2014-15.
Reigning MVP Jackson threw for 204 yards and a touchdown, while he rushed for 54 yards in Houston, where the Ravens led 20-10 at half-time.
The Ravens rushed for 230 yards compared to the Texans' 51 as Mark Ingram II had 55 and a touchdown.
"We feel like we have the best backfield in the league. We just try to prove that, week in, week out," Ingram said.
MURRAY HAS CARDINALS SOARING
Murray continues to show why the Cardinals were so desperate to draft him with the number one pick last year after inspiring a 30-15 victory against the Washington Football Team.
Second-year quarterback Murray finished with 286 yards and a touchdown, while he ran for two TDs in a stunning display.
Murray – a dual-threat – put on a show as he ran with the ball and went for 14 and 21 yards to help the Cardinals improve to 2-0.
"As soon as I leave the pocket I survey the field," Murray said. "Seeing how the blocks were set up, they were set up pretty perfectly. Once I get a guy one on one, I like my chances."
Cardinals star DeAndre Hopkins had eight catches for 68 yards and a touchdown.
Meanwhile, Wilson fuelled the Seahawks to a 35-30 win over the New England Patriots.
Wilson was 21-of-28 for 288 yards and five touchdowns as the Seahawks made it two victories from two games.
It condemned Can Newton and the Patriots to their first loss of the season after Tom Brady's QB replacement in New England finished 30 of 44 for 397 yards, a touchdown, interception and a sack in Seattle.
Week 2 scores:
Chicago Bears 17-13 New York Giants
Dallas Cowboys 40-39 Atlanta Falcons
Green Bay Packers 42-21 Detroit Lions
Tennessee Titans 33-30 Jacksonville Jaguars
Indianapolis Colts 28-11 Minnesota Vikings
Buffalo Bills 31-28 Miami Dolphins
San Francisco 49ers 31-13 New York Jets
Los Angeles Rams 37-19 Philadelphia Eagles
Pittsburgh Steelers 26-21 Denver Broncos
Tampa Bay Buccaneers 31-17 Carolina Panthers
Arizona Cardinals 30-15 Washington Football Team
Kansas City Chiefs 23-20 Los Angeles Chargers
Baltimore Ravens 33-16 Houston Texans
Seattle Seahawks 35-30 New England Patriots