The Cleveland Browns look set to field a significantly weakened team for Saturday's tussle with the Las Vegas Raiders after losing eight players to the reserve/COVID-19 list.

As they chase a ticket to the postseason, the 7-6 Browns are poised to have to rely on backups at a critical moment, with their ranks suddenly severely depleted.

It was revealed on Tuesday they have lost wide receiver Jarvis Landry, guard Wyatt Teller, tight end Austin Hooper, left tackle Jedrick Wills and defensive end Takkarist McKinley for now. Drew Forbes was named on the same list, with wide receiver JoJo Natson and tight end Ross Travis also sidelined.

The NFL.com website reported all have tested positive for the coronavirus. The Browns have not officially confirmed that to be the case.

Browns head coach Kevin Stefanski said meetings with players, virtual rather than in person, would take place during Tuesday afternoon.

He backed his squad to show they have sufficient quality to ride out the situation.

Stefanski said in a news conference: "We've seen, through last season, have seen it this year, guys step up. That's what the NFL's about. You're without guys due to injury or otherwise and guys step up. And that's why we have a bunch of players on this team that we trust."

It remains to be seen whether David Njoku, Anthony Walker Jr and punter Jamie Gillan, who all missed the 24-22 win over the Baltimore Ravens on Sunday due to being on the reserve/COVID-19 list, will be available for the game with the 6-7 Raiders.

Stefanski said, quoted on cleveland.com: "I don't have an update on those guys in particular. Again, we'll just follow the protocols on each one of them and then we're just going to focus on today. I think that's the prudent thing to do and make sure we do a great job with our virtual meetings, do a great job with this walkthrough."