Justin Herbert came up big at the death and Austin Ekeler dazzled as the Los Angeles Chargers avoided a stunning collapse after holding off Ben Roethlisberger's rallying Pittsburgh Steelers 41-37.

Herbert threw a 53-yard touchdown pass to Mike Williams with just over two minutes remaining as the Chargers outlasted the Steelers in a wild shoot-out on Sunday.

The Chargers led 27-10 entering the final quarter before Roethlisberger and the Steelers fought back to sensationally take a 37-34 lead behind Chris Boswell's 45-yard field goal with 3:24 remaining.

But the Chargers (6-4) avoided a mammoth collapse as Herbert found Williams four plays later to sink the Steelers (5-4-1), while Ekeler finished with a career-high four touchdowns.

Herbert became the first player in NFL history with 380-plus passing yards and 90-plus rushing yards in a game, per Stats Perform. The Chargers quarterback finished 30-of-41 passing for 382 yards and three TDs, while he rushed for another 90 yards – the most by a Chargers quarterback in a game.

With his third TD pass, Herbert improved to 53 touchdowns in his first 25 career starts, surpassing Tony Romo for fourth most in a player's opening 25 starts in the Super Bowl era – only Patrick Mahomes (68), Dan Marino (65) and Kurt Warner (59) had more.

As for Ekeler, who scored in every quarter, became the first player with multiple rushing touchdowns and multiple receiving TDs in a single game since Maurice Jones-Drew in 2011.

Steelers veteran Roethlisberger finished with three touchdowns on 28-of-44 passing for 273 yards.