Dallas Cowboys star Dak Prescott said it is "safe to say" he will return from injury and start against the Denver Broncos on Sunday.

A calf injury forced Prescott to miss last week's 20-16 win over the Minnesota Vikings, backup quarterback Cooper Rush sensationally fuelling the high-flying Cowboys.

After two weeks off to recover from a right calf strain, two-time Pro Bowler Prescott is now set to suit up to face the Broncos.

"Safe to say," Prescott told reporters on Thursday when asked if he would play on Sunday.

"I'm feeling good. Obviously I had two weeks to do a lot of rehab and recover, get everything that I needed to, the different modalities, and I feel good.

"Had two great days of practice and looking forward to Sunday."

The Cowboys (6-1) are averaging 40.3 points per game at home this season compared to 26.0 points per game on the road. Dallas have scored at least 36 points in five straight home games dating back to last season, according to Stats Perform.

In his first career NFL start, Rush threw for 325 yards and two touchdowns, including a 73-yard touchdown pass to Cedrick Wilson. The last Dallas quarterback to have a 70-yard TD pass in their first career NFL start was Roger Staubach in 1969.