Opener Tagenarine Chanderpaul and wicket-keeper/batsman Tevin Imlach notched late half-centuries as the Guyana Harpy Eagles ended day two of their fourth-round fixture against the Jamaica Scorpions with a 301-run second innings lead at Providence.
The hosts began the day 268-9 off 86.3 overs.
Harpy Eagles captain Leon Johnson carried on from his overnight 142 to finish 150* as Guyana were bowled out for 278 off 88.1 overs.
Marquino Mindley ended with 3-34 while Ojay Shields and Derval Green both ended with two wickets.
The Scorpions endured a horrendous start to their reply losing half of the team for just 24 runs inside six overs and three balls.
Eventually, they found themselves 64-9 in the 18th over before a39-run 10th wicket partnership between Derval Green and Nicholson Gordon meant they entered the lunch break 103-9 off 27 overs.
The pair added 12 more runs after lunch before Green fell for a top score 42 as the Scorpions were dismissed for 115 in 35.5 overs.
Nial Smith ended with 5-39 while Veerasammy Permaul and Ronsford Beaton took 3-22 and 2-22, respectively.
Mindley then led a Scorpions fightback before tea as he grabbed four quick wickets, including that of Leon Johnson, within the first 12 overs of the Harpy Eagles second innings.
The score at tea was 37-4 with Tagenarine Chanderpaul on 14 and Tevin Imlach yet to get off the mark.
After tea, Chanderpaul and Imlach continued on to leave the Harpy Eagles 138-4 at stumps, a lead of 301 runs with Chanderpaul on 60 and Imlach on 50.