After three straight losses in all competitions, Los Angeles FC responded by thrashing the San Jose Earthquakes 5-1 at Banc of California Stadium.
Diego Rossi's beautiful finish into the corner opened the scoring after a poor turnover of possession by the Earthquakes in the 21st minute.
But LAFC had to wait until the second half to truly take control.
Another bad turnover allowed Bradley Wright-Phillips through to double the lead, before Jose Cifuentes made it 3-0.
Rossi added his second in the 69th minute before Danny Musovski made it 5-0, Danny Hoesen later adding a consolation goal for San Jose.
The win lifted LAFC up into third in the Western Conference, with San Jose sitting 11th.
The Galaxy made it three straight wins by edging the Portland Timbers 3-2 at Providence Park.
Efrain Alvarez opened the scoring for the Galaxy, completing a fine team move with a finish into the top corner from inside the area.
It took until five minutes into the second half for the visitors to double their lead through Cristian Pavon's individual effort.
Felipe Mora gave Portland hope with a 67th-minute goal, but Joe Corona struck for the Galaxy with a wonderful 20-yard strike.
Diego Valeri came off the bench to add a second for Portland in additional time.
The Timbers are sixth in the Western Conference, one spot behind the Galaxy while being level on points.
Columbus Crew returned to the top of the Eastern Conference after a 1-0 win over Philadelphia Union.
Lucas Zelarayan's deflected 25-yard effort in the 55th minute was enough for Columbus.
Elsewhere, Western Conference leaders Sporting Kansas City were held to a 1-1 draw by Dallas.
Real Salt Lake and the Seattle Sounders drew 2-2 in a clash that featured a screamer from Pablo Ruiz, while Orlando City played out a 1-1 draw with Nashville.
New York City overcame New England Revolution 2-0, Houston Dynamo beat Minnesota United 3-0 and Erik Sorga scored a 98th-minute winner for DC United as they edged the New York Red Bulls 1-0.
Atlanta United and Inter Miami drew 0-0, while Cincinnati's clash with Chicago Fire also finished goalless.
Montreal trailed 2-0 after 14 minutes and 4-2 after 46 minutes, but Ahmed Hamdi scored twice in the final 16 minutes to give the home side a wild victory.
In Nashville, Hany Mukhtar scored in the 10th, 13th and 16th minutes on the way to a 5-1 rout of Chicago Fire.
The six-minute span was the second-shortest for a hat-trick in MLS history after LA Galaxy's Harut Karapetyan needed just five minutes to score three in a 1998 match.
Gustavo Bou's team-leading seventh goal gave New England Revolution a 1-0 win at Atlanta United, snapping a three-game win drought for the Eastern Conference leaders.
Second-half goals from Deiber Caicedo and Cristian Dajome gave Vancouver just their third win from 13 games this season, a 2-1 triumph over LA Galaxy.
Darlington Nagbe's impressive individual effort opened the scoring in a 2-1 Columbus Crew win over New York City FC.
Nani's 77th-minute penalty gave Orlando City a 1-1 draw with Toronto after Jozy Altidore had opened the scoring five minutes earlier, while Cole Bassett's second-half goal for Colorado Rapids earned a 1-1 draw against San Jose.
Kacper Przybylko's 83rd-minute decider gave Philadelphia Union a 2-1 victory over DC United, while Jeremy Ebobisse scored in the 84th minute to lift Portland past Dallas 1-0.
Carlos Vela's left-footed rocket in the 79th minute was the difference in LAFC's 2-1 home win over Real Salt Lake.
The New York Red Bulls-Inter Miami match was postponed due to weather.
Columbus made it five wins in six MLS games this season with a 3-0 victory over Chicago Fire on Thursday.
Gyasi Zardes scored and also missed a penalty as Darlington Nagbe scored a stunner at MAPFRE Stadium.
Derrick Etienne found the bottom corner from a Milton Valenzuela pass to open the scoring for Columbus in the 20th minute.
Zardes put a penalty over the crossbar just before half-time and Columbus left it late to seal their win.
Nagbe flicked the ball up to himself 30 yards from goal before unleashing a stunning volley into the corner to make it 2-0.
Zardes sealed the win in the 88th minute, tapping in Pedro Santos' cross as the Crew moved four points clear atop the conference.
The Hudson River Derby went the Red Bulls' way as they recorded a 1-0 win over New York City.
Kyle Duncan's powerful 20-yard strike just before the hour-mark was spilled by City goalkeeper Sean Johnson and awarded after a VAR review.
The Red Bulls are third in the Eastern Conference, while New York City are second last.
In the day's other game, New England Revolution and Philadelphia Union drew 0-0.
Orlando had taken the lead in the 10th minute from Benji Michel's cool finish and Andrea Perea doubled their advantage in the 58th minute when he met ex-Manchester United winger Nani's right-flank cross.
Philadelphia found a route back into the game when Kacper Przybylko netted with a first-time 68th-minute strike but they could not find an equaliser.
Union came close when City keeper Pedro Gallese made a fine stop to deny Jack Elliott with Jack McGlynn's effort from the rebound hitting the post.
Orlando, who were winless in their past three games, move up to second in the east on 25 points from 14 games.
Union have now only won one of their past five games and are third in the east with 23 points from five games.
Raul Ruidiaz scored a spectacular long-range goal to lift Seattle Sounders back into top spot overall with a hard-fought 1-0 win at Austin.
Ruidiaz moved into the outright lead for most goals this season with his 11th strike, which came in stunning style.
The Peruvian swooped a loose ball, spotting Austin keeper Brad Stuver off his line and expertly firing in from range for the 67th-minute winner.
Austin thought they had a 77th-minute equaliser which was disallowed by the VAR, while Ruidiaz also had a potential second ruled out for offside.
Seattle, whose 13-game unbeaten run ended on Sunday, are up to 32 points from 15 games atop the Western Conference.
Tesho Akindele scored the fastest goal in club history as Orlando got off to a quick start at home to Jaap Stam's Cincinnati on Saturday.
Akindele found the back of the net after just 33 seconds, surpassing the Orlando record set by Chris Mueller (62 seconds) in April 2018.
Nani doubled the lead in stunning fashion in the 19th minute – the former Manchester United star leaving Yuya Kubo on the floor after cutting to his right foot and then his left as he curled the ball past Przemyslaw Tyton.
After Nani hit the post minutes later and saw his shot saved by Cincinnati goalkeeper Tyton just past the hour mark, Junior Urso sealed the victory with 10 minutes remaining.
Orlando – who remain unbeaten through three games – are third in the Eastern Conference, behind leaders New England Revolution and second-placed New York City.
The Revolution edged Atlanta United 2-1 and New York City defeated reigning Supporters' Shield winners Philadelphia Union 2-0.
The Earthquakes and Dallas, meanwhile, both won 4-1 against DC United and Portland Timbers respectively.
Jackson Yueill's brace and a pair of assists from Cade Cowell fuelled the Earthquakes, who are top of the Western Conference on goal difference but level on points with Real Salt Lake, LA Galaxy and Austin FC.
Dallas showed no mercy at home to the Timbers after Andres Ricaurte and Jader Obrian scored in the opening 13 minutes.
Real Salt Lake came from behind to top Sporting Kansas City 3-1 courtesy of Rubio Rubin's second-half double, while MLS newcomers Austin prevailed 1-0 against Minnesota United.
Elsewhere, New York Red Bulls were 2-0 winners over Chicago Fire, defending champions Columbus Crew were held to a goalless draw by Montreal Impact and Houston Dynamo and Los Angeles FC played out a 1-1 draw.
Bruce Arena's side, who clinched their first-ever Supporters' Shield on Saturday, won thanks to Tajon Buchanan's 74th-minute strike.
The result took Revolution's season tally to 73 points from 33 games, eclipsing the previous record mark held by LAFC with 72 points in 2019.
New England have one more regular season match to extend their record, playing Inter Miami at home on November 7.
Canada international Buchanan came up with the winner, showing fast feet to make space for a low shot that beat Rapids goalkeeper William Yarbrough, who had sensationally kept out Henry Kessler from close range minutes earlier.
New York Red Bulls slipped out of the Eastern Conference play-offs spots after a 1-0 defeat to DC United who moved above them into seventh place.
United snapped a four-game winless skid, while also ending the Red Bulls' four-game running run and eight-game unbeaten streak in the process. Kevin Paredes side-footed home the ninth-minute winner for United.
Sporting KC moved into top spot in the Western Conference and dented LA Galaxy's play-offs aspirations with a 2-0 win.
Johnny Russell extended his scoring run to eight straight games with both goals for KC who clinched a top-four seeding as well.
Randall Leal scored two goals and grabbed an assist as Nashville came from two goals down twice to win 6-3 at Cincinnati.
Portland Timbers moved in the west's top four with a 2-0 home victory over San Jose Earthquakes, while Vancouver Whitecaps climbed up to fifth with a 2-1 triumph over Minnesota United.
New York City boosted their Eastern Conference top-four seed hopes with a 1-0 home win over Chicago Fire, while Josef Martinez's winner helped Atlanta United past Inter Miami 2-1 after Gonzalo Higuain had opened the scoring from the spot.
Columbus Crew upset Orlando City 3-2, Toronto held Philadelphia Union 2-2 as Jozy Altidore netted while Real Salt Lake scored twice in the final 10 minutes to win 2-1 at Dallas.
After failing to score in their opening two games – a 1-0 loss to LA Galaxy and a goalless draw with Vancouver Whitecaps – City hit the lead after only seven minutes, with Alexander Callens rifling home after Montreal failed to clear their lines from a corner.
Santiago Rodriguez spectacularly chipped Sebastian Breza to double the margin on 20, but only after Montreal gifted City possession in an attempt to play out from their own half.
Zachary Brault-Guillard pulled one back for CFM, but following further City goals from Telles Magno and Thiago Andrade, the scoreline arguably belied the performance.
Douglas Costa opened his account in the MLS later on Saturday, scoring the equaliser in LA Galaxy's 3-2 loss away to Seattle Sounders.
Javier Hernandez gave the Galaxy a shock lead in the sixth minute, after fine link-up play between Raheem Edwards and Kevin Cabral, but the Sounders fought back to lead before the interval – with goals from Jordan Morris and Fredy Montero.
Costa drew the visitors level from the dead ball after 48 minutes, wrong-footing Stefan Frei, but Xavier Arreaga headed home in the 72nd to give the Sounders their first win of the season.
Los Angeles FC continued their unbeaten start to the season, meanwhile, grinding out a 2-0 win against a 10-man Inter Miami at DRV PNK Stadium.
A deflected Carlos Vela pass put Kwadwo Opoku through on the stroke of the interval, and the 20-year-old Ghanaian finished with composure. That didn't spell the end of events in the first half, though, as Brek Shea was given a straight red card in injury time.
LAFC had six shots for the match compared Inter's seven, despite 53 per cent possession and an extra man. However, an Ismael Tajouri free-kick crept inside Inters back post in the 82nd minute to secure the win.
Steve Cherundolo's side are equal top in the Western Conference with Real Salt Lake, who defeated New England Revolution 3-2. Austin FC couldn't keep pace in the final Saturday game, however, going down 1-0 away to Portland Timbers through a Bill Tuiloma goal.
Columbus Crew share the lead in the Eastern Conference, following their 2-1 win over Toronto FC. They are joined by Philadelphia Union, who defeated San Jose Earthquakes 2-0.
A Darwin Quintero brace handed Houston Dynamo a 2-0 win against Vancouver Whitecaps, while Brandon Vazquez scored a double of his own in FC Cincinnati's 2-1 win at Orlando City.
FC Dallas, Chicago Fire and Colorado Rapids respectively secured 2-0 victories over Nashville, DC United and Sporting Kansas City in Saturday's other games.
Alexandre Pato's 94th-minute free-kick cannoned into the crossbar, with Andres Perea forcing home the rebound, ushering in scenes of celebrations as it would have sealed a post-season berth for Orlando.
That jubilation turned into frustration when the goal was later disallowed after referee Allen Chapman consulted the video, deeming Daryl Dike committed a foul on Alistair Johnston amid the goal-line scramble.
"It's a very sad day for the league," Orlando head coach Oscar Pareja said. "There is no explanation on a play that we saw evident. And it destroyed the joy of our people."
United States international Dike had earlier opened the scoring in the 18th minute, before Hany Mukhtar levelled it up for Nashville eight minutes into the second half.
Orlando – fifth in the Eastern Conference – can still reach the play-offs if they beat Montreal on the final day of the season on Sunday, while Nashville are third.
Philadelphia Union moved above Nashville into second in the east with their routine 2-0 home victory over struggling FC Cincinnati.
The Union are ahead of Nashville on goal difference only, with strikes from Daniel Gazdag and Paxten Aaronson securing the win.
Cincinnati are eight points adrift at the foot of the table and have lost 11 games in a row and 14 of their past 15, while they have only one win in their past 24 games.
Elsewhere, Minnesota United stayed firmly in the play-off hunt thanks to a 2-1 home win over Western Conference leaders Sporting Kansas City.
Dominique Badji's 58th-minute goal was enough for Colorado Rapids to edge Houston Dynamo 1-0, meaning they tied their club record for points in a season with 58.
A 2-1 victory over the Chicago Fire saw Philadelphia push three points clear of Toronto in the Eastern Conference, and for the Supporters' Shield, which they are bidding to win for the first time.
Kacper Przybylko opened the scoring from the penalty spot approaching the half-hour mark, following a handball in the area.
Chicago's chances of a comeback were dealt a blow nine minutes before half-time, Francisco Calvo sent off after a tackle on Alejandro Bedoya.
However, they managed to find an equaliser prior to the break as Robert Beric headed in from close range.
But Philadelphia scored what proved to be the winner in the 65th minute, when Cory Burke headed in a cross from Olivier Mbaizo.
According to Opta, Union became the first team to win their first eight home matches of an MLS season since San Jose in 2002, when the Earthquakes claimed their first 10.
The Timbers clinched a spot in the play-offs thanks to a 5-2 thrashing of the struggling LA Galaxy.
Jaroslaw Niezgoda scored a brace for Portland, who were 3-0 up after 30 minutes following Diego Valeri's penalty.
Eryk Williamson and Andy Polo also netted as the Timbers thrashed the Galaxy, who are bottom of the Western Conference.
Portland became the first team with multiple five-goal games against an opponent in a single MLS season since the Fire against the New York Red Bulls in 2008, having thrashed the Galaxy 6-3 earlier this month.
Chris Wondolowski scored a brace as the Earthquakes enjoyed a 2-0 win over Real Salt Lake.
It was his 24th multi-goal game in MLS. Only Landon Donovan (32) has more.
The New York Red Bulls left it late to edge the New England Revolution 1-0 and reach the play-offs, Sporting Kansas City overcame Cincinnati 1-0 and Orlando City thrashed Atlanta United 4-1.
New York City upset Toronto 1-0, Minnesota United beat the Colorado Rapids 2-1, DC United were too good for Columbus Crew 1-0, Dallas claimed a 2-1 win over Inter Miami and Los Angeles FC were 2-1 victors over the Houston Dynamo to clinch their play-off place.
Union, who are fifth in the Eastern Conference, went behind in the 10th minute when Przemyslaw Frankowski headed in Boris Sekulic's cross.
Chicago were reduced to 10 men when Wyatt Osmberg received a straight red card in the 34th minute, after VAR review, and Philadelphia capitalised from the ensuing free-kick.
German defender Kai Wagner scored the equalizer with a shot which went under the jumping Chicago wall.
Daniel Gazdag spurned a chance for Philadelphia with a header which went wide in the 52nd minute, while Union substitute Ilsinho fluffed a late volley.
Philadelphia have now won only one of their past seven games.
Nashville edged their way up to third in the Eastern Conference with a 1-1 draw at lowly Toronto.
Omar Gonzalez had headed Toronto ahead from a 19th-minute quick free-kick, but Robert Castellanos levelled before half-time from a long throw-in.
Union scored first-half goals from Alejandro Bedoya and Daniel Gazdag, while Sergio Santos had a goal disallowed on the stroke of half-time, as Philadelphia got some revenge after last season's Eastern Conference final defeat to City.
Bedoya put Philadelphia ahead in the 12th minute, but City thought they had an avenue back into the game when referee Ted Unkel awarded them a penalty and sent off Jack Elliott for a 28th-minute last-man push on Santiago Rodriguez.
However, VAR intervened and determined that Rodriguez had illegally used his hand in the lead-up, meaning the penalty and red card were overturned.
The win was Philadephia's first at Yankee Stadium and came despite City bossing the possession count with 74 percent.
Former Liverpool and Bayern Munich attacker Xherdan Shaqiri netted his first MLS goal as Chicago Fire won 3-1 over Sporting KC.
Shaqiri scored from the spot in the 50th minute to make it 2-0 as Chicago extended its unbeaten start to the new season with Kacper Przybylko hitting a double.
Jesus Ferreira scored a first-half hat-trick as Dallas defeated Portland Timbers 4-1 in a sign of intent for the forward ahead of USA's upcoming World Cup qualifiers.
All three of Ferreira's goals came in a 10-minute span, marking his first-ever MLS hat-trick.
Gonzalo Higuain scored, but Inter Miami remain winless this term after a 3-1 loss away to last season's strugglers Cincinnati.
The result leaves Phil Neville's side with an MLS-worst record of one point from four games, having conceded 10 goals and only scored two.
Karol Swiderski netted a double as Charlotte upset New England Revolution 3-1, while Luis Amarilla's 32nd-minute strike lifted Western Conference leaders Minnesota United past San Jose Earthquakes 1-0.
Tyler Pasher's 90th minute goal salvaged a 1-1 home draw for Houston Dynamo against Colorado Rapids, while 10-man Atlanta United scored twice in the final five minutes to rescue a 3-3 draw with Montreal.
Facundo Torres' early goal got Orlando City past LA Galaxy 1-0, Bob Bradley's Toronto knocked off DC United 2-1 and Real Salt Lake edge 10-man Nashville 2-1.
Javier 'Chicharito' Hernandez scored twice for the Galaxy in a 3-3 draw with Minnesota United on Decision Day, but RSL's last-gasp 1-0 win over Sporting Kansas City changed the landscape of the Western Conference.
RSL pipped the Galaxy – without post-season football for the second straight campaign – to the seventh and final play-off spot on victories for the season via a 95th-minute winner, having finished level on 48 points at the end of 34 rounds.
Minnesota finished fifth to clinch a post-season berth in the west, along with sixth-placed Vancouver Whitecaps, who drew 1-1 against Seattle Sounders.
Seattle's stalemate and Sporting KC's late loss allowed Colorado Rapids to secure top seed in the Western Conference following a 5-2 rout of Los Angeles FC, who were eliminated as a result.
In the Eastern Conference, Orlando City beat Montreal 2-0 for a spot in the play-offs, along with Atlanta United (2-1 over FC Cincinnati) and New York Red Bulls – the latter using a 1-1 draw against Nashville to extend their post-season streak to 12 years.
Supporters' Shield winners New England Revolution lost 1-0 to already eliminated Inter Miami, Portland Timbers eased past lowly Austin 3-0, DC United defeated Toronto 3-1, 10-man New York City drew 1-1 with Philadelphia Union and reigning champions Columbus Crew – who will not defend their title – beat Chicago Fire 2-0.
Chris Wondolowski scored in the San Jose Earthquakes' 1-1 draw against Dallas before the league's all-time leading scorer announced his retirement.
Fabio scored the 79th-minute winner, his second goal of the season, after Coronel had saved Mauricio Pereyra's penalty on the stroke of half-time.
Venezuelan midfielder Cristian Casseres fired in an excellent left-foot strike to open the scoring in the sixth minute but Orlando had a chance to level moments before half-time.
Uruguayan midfielder Pereyra shot low to Coronel's left but the Brazilian dived well and palmed away the spot-kick.
Pereyra partly made up for his miss, laying off the pass for Chris Mueller to equalize high into the back of the net in the 59th minute.
But Fabio held off a defender to fire home to secure the Red Bulls' first road win of the season, moving them up to seventh in the Eastern Conference.
DC United had seven different scorers as they trounced Toronto 7-1, keeping them ahead of the Red Bulls in sixth in the East.
Andy Najar, who did not score one of United's goals, set up two and was named Player of the Match.
Eastern Conference leaders New England Revolution blew a two-goal lead to draw 2-2 away to Columbus Crew.
Goals from Tajon Buchanan and Gustavo Bou had New England on the path to victory but Columbus fought back with Andrew Farrell's comical own goal levelling it up.
LAFC grabbed their maiden road win of the campaign, edging Real Salt Lake 1-0 after Jose Cifuentes' 69th-minute strike from Eddie Segura's pass.
Segura was the hero moments later with a diving goal-line clearance to deny Rubio Mendez's on-target lob.
Houston Dynamo and Cincinnati traded goals inside the opening five minutes in a 1-1 draw. Houston have drawn four games in a row.
Argentine forward Ignacio Aliseda scored twice as Chicago Fire claimed their second win of the season, triumphing 3-0 over Atlanta United.
Inter Miami's struggles continued with a 1-0 defeat away to Montreal. Miami have only managed eight points from 11 games, losing their past five.
Benjamin Kikanovic scored late to earn a 2-2 draw for struggling San Jose Earthquakes at Minnesota United. The Earthquakes are winless in eight.
Charles Sapong's second-minute goal was enough for Nashville to secure a 1-0 home win over fellow Eastern Conference contenders Philadelphia Union.
Clark – aged 17 years, four months and 18 days – became the youngest player to score in his first two MLS appearances on Wednesday, per Opta.
Hours after joining the Red Bulls, Clark capped his debut with a goal in Saturday's 1-0 win over Atlanta United.
Clark became the youngest player to score his maiden goal for the Red Bulls since Jozy Altidore in 2006.
He continued where he left off against Toronto, netting the equaliser with 13 minutes remaining midweek.
Following Alejandro Pozuelo's 23rd-minute penalty, Clark earned the visiting Red Bulls a point by firing a shot into the top corner of the net from outside the box.
The Red Bulls are seventh in the Eastern Conference, while Toronto – already play-off bound – remain top through 18 games.
Elsewhere, reigning Supporters' Shield holders Los Angeles FC and struggling LA Galaxy were beaten.
Lucas Cavallini's brace lifted Vancouver Whitecaps to a 2-1 victory against fourth-placed LAFC.
Canada international Cavallini has now scored in back-to-back games after finding the net just twice in his first 11 MLS matches for the Whitecaps, who climbed up to eighth in the standings and in the play-off positions.
As for the Western Conference's bottom side – the Galaxy – they were swept aside 4-0 by San Jose Earthquakes in the Cali Clasico.
Former Manchester United and Real Madrid striker Javier Hernandez was substituted early in the second half, with the Galaxy only managing four goals in the 652 minutes 'Chicharito' has been on the pitch this season.
It was a sixth consecutive defeat for the slumping Galaxy as the Earthquakes moved within a point of LAFC in the west.
Wednesday's scheduled Minnesota United-Chicago Fire fixture was postponed due to a suspected coronavirus case among Minnesota's team delegation.
In other results, New England Revolution edged Montreal Impact 3-2, FC Cincinnati were 2-1 winners over Columbus Crew, Orlando City and New York City drew 1-1, Atlanta saved a 1-1 draw at Inter Miami, Sporting Kansas City fell 1-0 to Dallas, DC United and Philadelphia Union shared the points in a four-goal clash, Real Salt Lake trumped Portland Timbers 2-1 and Nashville accounted for Houston Dynamo 3-1.
The resurgent Timbers continued their run thanks to goals from Dairon Asprilla and George Fochive at Providence Park.
Asprilla opened the scoring at home to LAFC – the Timbers forward headed home in the 21st minute, though the visitors responded six minutes later via Cristian Arango's penalty.
But the Timbers emerged triumphant courtesy of Fochive's game-winning header 22 minutes from the end in Portland.
The Timbers are fifth in the Western Conference – nine points behind leaders Sporting Kansas City, while LAFC are eighth and a point outside the play-off spots.
Elsewhere, Philadelphia Union returned to winning ways by defeating Orlando City 3-1 to surge back into the play-off positions.
The Union were three games without a win in MLS heading into the contest, however, Kacper Przybylko's brace ensured Philadelphia – eliminated in the CONCACAF Champions League semi-finals – snapped their skid.
After Philadelphia's Kai Wagner and Orlando's Ruan traded goals, Przybylko lifted the Union with a second-half brace.
Orlando ended the match with 10 men after Antonio Carlos was sent off in the 88th minute.
Montreal – fifth in the Eastern Conference – accounted for Chicago Fire 2-0 and Vancouver Whitecaps drew 1-1 at Colorado Rapids.
Meanwhile, Dallas and head coach Luchi Gonzalez parted ways amid their four-match winless streak which has left the team 11th in the west and seven points off the pace.
Cristian Roldan inspired Seattle to a 3-1 win over the Galaxy in California.
Roldan opened the scoring in the 12th minute, completing a fine team move by getting on the end of a Jordan Morris cross.
Morris doubled the lead seven minutes before half-time, finishing after a lovely pass from Nicolas Lodeiro.
Roldan produced a clinical finish from a Joao Paulo pass to make it 3-0 just after the hour-mark, with Seattle winning despite Sebastian Lletget's late goal for the LA Galaxy.
It marked Roldan's third multi-goal game in MLS, and two have come against the Galaxy.
Seattle are top of the Western Conference, equal on points with the Portland Timbers, who recorded a 1-0 win over the Vancouver Whitecaps.
After joining Inter Miami following his Juventus release, Higuain had a tough debut in a 3-0 loss to the Philadelphia Union.
Higuain hit the outside of the post with a bicycle kick and later put a penalty over the crossbar.
Anthony Fontana, Ilsinho and Brenden Aaronson scored for Philadelphia, who are second in the Eastern Conference.
Higuain, meanwhile, has failed to convert his past four penalties in all competitions.
Eastern Conference leaders Columbus Crew fell to a 3-1 loss to Toronto.
The New York Red Bulls thrashed the Montreal Impact 4-1, the New England Revolution beat DC United 2-0 and Chicago Fire overcame Atlanta United 2-0.
Minnesota United played out a goalless draw with Real Salt Lake, while Dallas' clash with Orlando City also finished 0-0.
The San Jose Earthquakes ended a nine-game winless run by beating Los Angeles FC 2-1.
Trailing 4-2 heading into the 90th minute, former Manchester United and Italy forward Giuseppe Rossi reduced the deficit for RSL in Portland – his first MLS goal.
And Sam Johnson completed the stunning comeback against the MLS is Back Tournament champions in the fourth minute of stoppage time.
In a wild showdown, the Timbers opened the scoring through Diego Chara in the sixth minute before RSL's Corey Baird restored parity 13 minutes later, but Jaroslaw Niezgoda's effort within two minutes ensured Portland led 2-1 at half-time.
After Real Salt Lake equalised again, this time courtesy of Damir Kreilach three minutes into the second half, Portland took control of the contest.
Sebastian Blanco's stunning effort with 20 minutes remaining and Felipe Mora's effort five minutes from time seemingly had the Timbers on track before the hosts capitulated.
The Timbers are fourth in the Western Conference, a point above RSL after seven matches.
LA Galaxy beat San Jose Earthquakes for the first time since 2018 thanks to their 3-2 triumph in the California Clasico.
Sebastian Lletget's 82nd-minute goal settled the five-goal thriller after the Earthquakes had led 1-0 and 2-1 against the Galaxy.
After posting just their second win in the regular season, the Galaxy are ninth in the west, while the Earthquakes are eighth.
In other results, Philadelphia Union crushed DC United 4-1, New York City accounted for Chicago Fire 3-1, Dallas defeated Minnesota United by the same scoreline and Orlando City also topped Atlanta United 3-1.
FC Cincinnati played out a 0-0 draw with Columbus Crew, New York Red Bulls drew 1-1 against New England Revolution, while Western Conference leaders Sporting Kansas City were held to a 1-1 draw by Colorado Rapids.
Alan Pulido, Luis Martins and Daniel Salloi all scored within 16 minutes as KC raced to a 3-0 lead. Salloi's classy volley took his tally to nine goals this MLS season.
Israeli midfielder Gadi Kinda added a fourth in the 58th minute with Graham Zusi getting his second assist, before LAFC got a consolation from Danny Musovski.
The win lifted Sporting KC past Seattle Sounders who conceded in the 90th minute to draw 1-1 at home with Dallas.
Fredy Montero had put the Sounders ahead in the 72nd minute with a set-piece header but Dallas equalised from Franco Jara's 90th-minute close-range strike.
Sporting KC are ahead of Seattle on goal difference, with both sides having 33 points, although the leaders have a game in hand.
LA Galaxy are third following a 1-0 victory over Real Salt Lake, secured by Efrain Alvarez's cool 53rd-minute winner.
Eastern Conference leaders New England extended their unbeaten run to five games with a 0-0 draw against Nashville, who slip to fourth despite the result.
The draw also extends Nashville's undefeated streak to nine games.
Former England international Kieran Gibbs netted a 66th-minute equaliser to earn Inter Miami a 1-1 draw away to fellow Florida outfit Orlando City. The goal was Gibbs' first in the MLS.
Philadelphia Union ended their three-game winless run with a 3-0 victory over Toronto after three first-half strikes.
Ola Kamara and Yordy Reyna both netted doubles as DC United won 4-2 over Columbus Crew.
Tomas Pochettino scored a first-half brace as struggling Austin won 3-2 over Houston Dynamo.
Chicago Fire and 10-man New York City played out a goalless draw, while New York Red Bulls and Cincinnati also ended 0-0 and Portland Timbers drew 1-1 with San Jose Earthquakes.
Sergio Santos netted three times as Philadelphia crushed Toronto 5-0 at Subaru Park on Saturday.
The result equalled the Union's biggest ever win and Toronto's largest defeat, as per Opta.
Philadelphia needed until the 27th minute to get going, Sergio Santos heading in a wonderful cross from Kai Wagner.
Just six minutes later and the hosts doubled their lead, Mark McKenzie heading in from close range after a corner.
Jamiro scored a spectacular third for Eastern Conference leaders Philadelphia in the 56th minute, his 20-yard effort going in off the underside of the crossbar.
Sergio Santos put away two more to complete his hat-trick – the fourth in the Union's history and first since C.J. Sapong in May 2017.
Western Conference leaders Sporting also enjoyed a fine win, thrashing the Colorado Rapids 4-0.
Alan Pulido, Andreu Fontas, Gadi Kinda and Gerso Fernandes netted in the victory.
Leandro Gonzalez Pirez's 89th-minute winner saw Inter Miami – without the suspended Gonzalo Higuain – edge Orlando City 2-1, while DC United overcame Atlanta United 2-1.
New York City recorded a 3-1 victory over the Montreal Impact and the Vancouver Whitecaps were too good for the San Jose Earthquakes 2-1.
The Chicago Fire and New York Red Bulls drew 2-2, Minnesota United edged Cincinnati 1-0, Houston Dynamo and Columbus Crew drew 1-1 and Real Salt Lake and Dallas played out a goalless draw.
Seattle are atop the Western Conference on 57 points, second only to runaway Eastern Conference leaders and Supporters' Shield pacesetters New England Revolution (65), who already have secured the top seed on their side.
The Sounders established themselves early with goals from Shane O'Neill in the fifth minute and Nicolas Benezet in the 14th at home to the Whitecaps amid their 13-game winless run against Seattle – the club's longest drought against any opponent in MLS.
After Vancouver clawed a goal back via Brian White at the end of the first half, Will Bruin added a third for Seattle 10 minutes into the second period and Leo Chu netted in the 90th minute to close it out.
New York Red Bulls kept their play-off hopes alive, defeating slumping Inter Miami 1-0 behind a 25th-minute goal courtesy of Patryk Klimala.
The Red Bulls sit ninth in the east, three points adrift of Montreal, rivals New York City and DC United, who currently hold the final three post-season positions.
Inter Miami are eight points off the pace amid a five-match losing streak.
FC Cincinnati became the first team officially eliminated from play-off contention following a 2-1 home defeat to third-placed Philadelphia Union.
Though Philadelphia had possession for only 37 per cent of the match, they built a lead through Kacper Przybylko in first-half stoppage time before Paxten Aaronson doubled the advantage 11 minutes into the second half.
Haris Medunjanin netted in the 82nd minute but it was too late as Cincinnati suffered their 16th loss of the season against eight draws and an MLS-worst four wins.
