Messi gave a tearful farewell to Barca at a news conference on Sunday after it was confirmed this week the forward's 21-year association with the club has come to an end.
The six-time Ballon d'Or winner's name was chanted by home supporters throughout the prestige pre-season match with Juve, who included Cristiano Ronaldo in their starting line-up.
Memphis Depay gave Barca the lead after three minutes and Martin Braithwaite added a second before the hour mark as Ronald Koeman's men rounded off pre-season with a win, with Riqui Puig scoring a fine third with the last kick of the contest.
New signings Yusuf Demir and Depay linked up for Barca's early opener, with the latter taking a throughball in his stride and picking his spot past Wojciech Szczesny.
That was Depay's third goal in four games since arriving from Lyon on a free transfer and he nearly had a second soon after when bending a free-kick narrowly over the crossbar.
Ronaldo was kept largely quiet during his 45 minutes on the pitch but did test Neto with a vicious shot in the first half, while Alvaro Morata was twice denied by the Barca keeper.
The hosts had some breathing space 12 minutes into the second period as Braithwaite's header from a Depay corner squirmed through the grasp of substitute keeper Mattia Perin.
Barca added a third goal to their tally in the final seconds through young midfielder Puig's curled effort from 20 yards to give Koeman hope of a bright future without club legend Messi.
With David Beckham among their owners, Inter Miami are preparing for their debut MLS season beginning next month.
Messi has been linked with the MLS club previously and those rumours are persisting.
TOP STORY – MESSI STILL A TARGET FOR INTER MIAMI
Barcelona great Messi is among the stars who could sign for Inter Miami, according to OKdiario.
Real Madrid midfielder Luka Modric and Paris Saint-Germain striker Edinson Cavaniare also possibilities, the report says.
Messi reportedly bought an apartment in Miami in December, while he can leave Barcelona for free at season's end despite being contracted until 2021.
ROUND-UP
- Juventus have other plans should Paul Pogba not return to the club from Manchester United in the close season. Sport reports the Serie A giants are considering a move for Bayern Munich midfielder Thiago Alcantara, whose contract expires next year.
- Barcelona will announce Leganes striker Martin Braithwaite as their latest signing on Thursday, according to AS, which reports the LaLiga club are set to pay €18million for the Denmark international.
- Linked with RB Leipzig star Timo Werner, Liverpoolare seemingly considering their options. Bild reports the European champions are tracking Milot Rashica, the 23-year-old who has scored 10 goals in 21 games for struggling Werder Bremen this season.
- Hansi Flick's future is unclear. Bayern Munichwill wait until May to make a decision on the head coach, who has attracted interest from other clubs, according to Bild.
- Could Adam Lallana be set for a reunion with Brendan Rodgers? Sky Sports reports Leicester City have approached the Liverpool midfielder's representatives about a move at season's end. Lallana and Rodgers worked together at Anfield and the 31-year-old is coming out of contract.
- After an initial move for Marcos Alonso in January failed, Inter are still considering the Chelsea left-back, according to CalcioMercato. However, the report says the Serie A giants are unwilling to pay Chelsea's asking price of €30m (£25.1m).
The rapid winger was of interest to Tottenham in the off-season, when they were coached by former Wolves boss Nuno Espirito Santo.
Though Nuno's spell at Spurs was short-lived, it appears Antonio Conte is also an admirer of Traore.
TOP STORY: SPURS TO MAKE TRAORE MOVE?
Tottenham are looking for reinforcements this month, as they aim to provide Antonio Conte with the resources he needs to push for Champions League qualification. However, they were dealt a blow this week when Conte confirmed Son Heung-min is set to miss the rest of January with a muscular injury.
With Son out, Sky Sports believes Tottenham will reignite their interest in Traore, a player they wanted to sign before the season started.
The report also states that Spurs may bring in Traore to provide competition for both an attacking role and right wing-back duties in Conte's preferred 3-4-3 or 3-5-2 shape.
ROUND-UP
- According to Fichajes, two Premier League clubs are interested in signing Barcelona forward Martin Braithwaite .
- Sky Sports reports that Aston Villa wish to sign Brighton and Hove Albion midfielder Yves Bissouma this month.
- The same outlet has also claimed that Real Madrid's Gareth Bale may consider a move to the Championship, with Swansea City or Cardiff City mooted as possible destinations.
- Fabrizio Romano has said that Paris Saint-Germain midfielder Georginio Wijnaldum is unlikely to join Arsenal in January.
- According to the presenter Oriol Domenech on TV3, Barca president Joan Laporta has been telling people close to him that he is very confident of signing Erling Haaland later this year.
- Manchester United are preparing a bid for PSG forward Mauro Icardi, should Anthony Martial and Edinson Cavani leave the club, L'Equipe reports.
- Gianluca Di Marzio has reported that Juventushave received several offers for midfielder Arthur, who could leave this month.
