Dani Carvajal impressed in El Clasico at the weekend, with the Real Madrid right-back slotting into a defence in front of Crystal Palace's Spanish goalkeeper Vicente Guaita.
Marcos Alonso is in the team after returning to form with Chelsea, the full-back scoring both goals as the Blues drew with Bournemouth.
The other Spaniard in the starting line-up is Atletico Madrid's Saul Niguez, while Ismaila Sarr takes a place on the bench after he stole the show in Watford's shock 3-0 win over Liverpool, whose 44-match unbeaten run in the Premier League ended abruptly at Vicarage Road.
Below, we have the entire squad.
TEAM OF THE WEEK
GK:Vicente Guaita (Crystal Palace) – 82
RB:Dani Carvajal (Real Madrid) – 87
CB:Kostas Manolas (Roma) – 86
LB: Ramy Bensebaini (Borussia Monchengladbach) – 84
RM:Calvin Stengs (AZ) – 84
CM:Saul Niguez (Atletico Madrid) – 87
LWB:Marcos Alonso (Chelsea) – 86
LW:Philippe Coutinho (Bayern Munich) – 89
LM:Fabian Orellana (Eibar) – 84
ST:Duvan Zapata (Atalanta) – 86
ST:Dario Benedetto (Marseille) – 84
SUBSTITUTES
GK: Predrag Rajkovic (Reims) – 79
LB:Marcal (Lyon) – 81
RM:Ismaila Sarr (Watford) – 82
CM: Teji Savanier (Montpellier) – 82
CF: Andre-Pierre Gignac (Tigres) – 83
ST:Nikola Kalinic (Roma) – 82
ST:Dieumerci Mbokani (Antwerp) – 82
RESERVES
RB:Matias Rodriguez (Deportes Nunoa) – 78
LM: Danny Blum (Bochum) – 78
ST: Klauss (LASK) – 77
GK:Daniel Akpeyi (Kaizer Chiefs) – 75
LF: Max Burgess (Western United) – 73
Chelsea have been aggressive in their hunt for centre-backs during this transfer period after Antonio Rudiger and Andreas Christensen left the club.
But while they have secured the services of Kalidou Koulibaly, they are still after at least one more, having previously enquired about Matthijs de Ligt, Martin Skriniar and a number of others.
Pulisic has been a recurring name when it comes to players Chelsea are seemingly willing to part ways with, and while a loan move has been weighed up, a swap for Maguire could solve problems for both clubs if United feel he is no longer part of Erik ten Hag's vision.
TOP STORY – BLOCKBUSTER SWAP COULD SEND UNITED CAPTAIN TO CHELSEA
Chelsea have made their interest in 21-year-old Leicester City centre-back Wesley Fofana clear, but if they are not willing to meet the gaudy £85millon asking price, a swap deal for a player surplus to requirements would be far more palatable.
For United, who are reportedly operating under a stricter budget, landing a 23-year-old with 19 goals and 10 assists over the past three Premier League seasons in exchange for a 29-year-old centre-back could be exactly what they are looking for, but it all depends on how Ten Hag values Maguire.
According to the Daily Mail's report, there is a belief Maguire may be dropped from United's team set to play Liverpool this weekend, which would only add fuel to the fire.
ROUND UP
– The Athletic reports that Chelseahave offered £15million plus left-back Marcos Alonso to Barcelonain their bid for Pierre-Emerick Aubameyang.
– According to the Telegraph, Real Madrid are considering a move for Tottenham's Pierre-Emile Hojbjerg as a potential replacement for Casemiro.
– 90min claim Newcastle Unitedand West Hamare monitoring United's Scott McTominay if he is squeezed out by the arrival of Casemiro.
– Leeds United are hoping to secure a £4m move for 18-year-old FC Zurich striker Willy Gnonto, who became Italy's youngest ever senior international goalscorer in a loss to Germany in June.
– Mail Online reports that Arsenalexpect Bukayo Saka to sign a new contract at Emirates Stadium, despite interest from rival clubs including Manchester City.
With David Beckham among their owners, Inter Miami are preparing for their debut MLS season beginning next month.
Messi has been linked with the MLS club previously and those rumours are persisting.
TOP STORY – MESSI STILL A TARGET FOR INTER MIAMI
Barcelona great Messi is among the stars who could sign for Inter Miami, according to OKdiario.
Real Madrid midfielder Luka Modric and Paris Saint-Germain striker Edinson Cavaniare also possibilities, the report says.
Messi reportedly bought an apartment in Miami in December, while he can leave Barcelona for free at season's end despite being contracted until 2021.
ROUND-UP
- Juventus have other plans should Paul Pogba not return to the club from Manchester United in the close season. Sport reports the Serie A giants are considering a move for Bayern Munich midfielder Thiago Alcantara, whose contract expires next year.
- Barcelona will announce Leganes striker Martin Braithwaite as their latest signing on Thursday, according to AS, which reports the LaLiga club are set to pay €18million for the Denmark international.
- Linked with RB Leipzig star Timo Werner, Liverpoolare seemingly considering their options. Bild reports the European champions are tracking Milot Rashica, the 23-year-old who has scored 10 goals in 21 games for struggling Werder Bremen this season.
- Hansi Flick's future is unclear. Bayern Munichwill wait until May to make a decision on the head coach, who has attracted interest from other clubs, according to Bild.
- Could Adam Lallana be set for a reunion with Brendan Rodgers? Sky Sports reports Leicester City have approached the Liverpool midfielder's representatives about a move at season's end. Lallana and Rodgers worked together at Anfield and the 31-year-old is coming out of contract.
- After an initial move for Marcos Alonso in January failed, Inter are still considering the Chelsea left-back, according to CalcioMercato. However, the report says the Serie A giants are unwilling to pay Chelsea's asking price of €30m (£25.1m).