Ivo Karlovic

Edmund – the eighth seed – defeated Japanese opponent Yasutaka Uchiyama 7-5 6-4 at the ATP Tour 250 tournament on Tuesday.

The Brit won 86 per cent of his first serves as he earned a clash with Dominik Koepfer after one hour, 44 minutes.

German Koepfer defeated last year's runner-up Brayden Schnur 7-5 6-4 in the opening round.

Kevin Anderson – the 2018 champion in New York – was stunned 7-6 (8-6) 6-4 by qualifier Jason Jung, who will face Cameron Norrie after the seventh seed beat Brian Shi 7-5 6-3.

Elsewhere, Jordan Thompson accounted for veteran Ivo Karlovic 6-3 7-6 (7-2), Yoshihito Nishioka outlasted Henri Laaksonen 6-3 0-6 6-2, Paolo Lorenzi prevailed 4-6 6-4 6-0 over Danilo Petrovic and Go Soeda went down 6-2 6-7 (2-7) 6-3 to Kwon Soon-woo.

At the Argentina Open, Cecchinato's title defence was ended by Roberto Carballes Baena in the first round.

Cecchinato was upstaged 6-4 7-6 (7-3) by Carballes Baena, who saved five of six break points on the clay in Buenos Aires.

Next up is Casper Ruud after the eighth seed blitzed Pablo Andujar 6-2 6-3.

Fellow seed Laslo Djere and Albert Ramos-Vinolas also progressed to the last 16, along with Facundo Bagnis, Juan Ignacio Londero, Pedro Sousa, Pedro Martinez and Jozef Kovalik.

Ivo Karlovic – one of only two tennis stars taller than the giant Isner – had set the benchmark with 13,728 across his career, the most since aces were first tracked in 1991.

But Isner has chipped away at that total over the course of this week at the All England Club.

The American's 54 aces in five sets against Enzo Couacaud in the first round made him the first player to pass 50 in a grand slam match since he had last done so versus Steven Johnson at the 2020 US Open.

And there were a further 36 in an epic second-round win over Andy Murray, leaving Isner just four short of matching Karlovic and five away from passing him.

Against Jannik Sinner, in Friday's third round, Isner raced past his target, tallying 12 aces in the first set alone.

It is a record Isner is likely to own for some time, with 43-year-old Karlovic absent from the ATP Tour this year and playing only six main-draw matches in 2021.

Roger Federer is third on the list, way back on 11,478.