Westbrook misses out as Lakers lose again, Warriors' winning streak snapped by Jazz
A day after hinting at his unhappiness at coach Frank Vogel, and with lingering doubts over his future ahead of Thursday's trade deadline, Westbrook watched from the bench.
It is the first game the nine-time All-Star has missed all season, though Vogel could at least still call upon the likes of LeBron James and Anthony Davis from the beginning.
James scored 30 points for the Lakers, who led 54-47 at half-time, only for the depleted Trail Blazers to slowly turn things around before rallying in the fourth quarter.
Anfernee Simons led the scoring for Portland with 29 points, while Jusuf Nurkic added 19 points and 12 rebounds as the hosts held on to snap a six-game losing streak.
Bogdanovic and Mitchell inspire Jazz to victory
The Golden State Warriors' nine-game winning streak was ended in emphatic style as they fell to a 111-85 defeat to the Utah Jazz.
Without the injured Rudy Gobert for an eighth game, the Jazz were inspired to victory by 23-point Bojan Bogdanovic and Donovan Mitchell, who had 14 points and 10 rebounds.
The Warriors, without Klay Thompson, Andre Iguodala and James Wiseman, finished with a shooting percentage of 36 per cent in what was their heaviest defeat of the season.
DeRozan stars again
Five-time NBA All-Star DeMar DeRozan was serenaded by "MVP!" chants after scoring 36 points in the Chicago Bulls' 121-109 victory over the out-of-form Charlotte Hornets.
DeRozan hit 30 points for a fourth game running, during which time he has averaged 37.5 points, while Nikola Vucevic finished with 18 points, 15 rebounds and eight assists.
Elsewhere on Wednesday, Darius Garland's 27 points on his return from a back injury helped the Cleveland Cavaliers to a 105-92 win against the San Antonio Spurs.
The Toronto Raptors beat the Oklahoma City Thunder 117-98 for their seventh straight win and the Sacramento Kings were 132-119 victors against the Minnesota Timberwolves.