Player-of-the-Match Dottin, who hit 18 fours and two sixes in her 146-ball innings, got support from Hayley Matthews, who scored 57 and took three wickets for the West Indies. Together they put on 119 runs for the third wicket after the West Indies had lost Rashada Williams for 15 and Captain Stafanie Taylor for six to leave the visitors on 72-2.
Dottin would also share in a 44-run fourth-wicket partnership with Shemaine Campbelle, who made 23.
Left-arm spinner Anan Amin returned figures of 5-35 for Pakistan.
Chasing 254 for victory, Pakistan were in early trouble at 51-3 after Shakera Selman removed Sidra Ameen for two and Ayesha Zafar for 17 and Anisa Mohammed took the wicket of Muneeba Ali for 28.
However, Kainat Imtiaz (24) and Iram Javed (40) shared in a 57-run partnership and Aliya Riaz and Captain Sidra Nawaz, stitched together a sixth-wicket partnership of 43, to keep the West Indies bowling at bay.
However, they were unable to score freely and fell well behind the required rate of scoring as Hayley Matthews 3-31 and Selman 2-35 tightened the screws. Riaz was eventually run out for 46, effectively ending any chance of a victory as the hosts ended on 208-9.
Chasing Pakistan’s Women’s 225-7, Taylor scored 102 not out after coming to the rescue of her team that has slumped to 15-3 within the first five overs.
Taylor shared in an 83-run fourth-wicket partnership with Hayley Matthews, who made 49, and then a match-winning unbroken partnership of 128 with Chedean Nation, who scored 51 not out, her maiden ODI half-century.
Taylor faced 117 balls for her score that included 12 fours while Nation struck seven boundaries facing 67 balls during the match-winning stand.
Anam Amin, who did the early damage by dismissing the in-form Diandra Dottin for 4 and Shemaine Campbelle for one, finished with 2-45 from her 10 overs. Diana Baig, who dismissed Rashada Williams for 6, returned figures of 1-36 from her eight overs.
Sadia Iqbal, who snagged Matthews’ wicket, finished with 1-36 from seven overs.
Earlier, sent in to bat, Pakistan Women owed their best score of the series to opener Muneeba Ali, who scored a patient 58. She and Ayesha Zafar staged an opening stand of 49 before the latter was out caught and bowled by Aaliyah Alleyne (2-41) for 13.
Ali and Javeria Khan put on 74 over the next 20 overs as the West Indies bowlers tightened their grip on the innings. Ali eventually fell to Taylor in the 31st over with the score on 123. Six runs later, the pressure began to take a toll as Taylor ran Khan out for 13.
Two balls later, Alleyne picked up her second wicket when she bowled Omaima Sohail for 27.
Iram Javed and Aliya Riaz held up the progress of the West Indies bowlers with a 44-run fifth-wicket stand that was eventually broken when Javed was dismissed by Shakera Selman for 26.
Riaz would eventually get Pakistan Women past 200 with her unbeaten 44 that helped set up a decent total for the West Indies Women to chase.
Selman took the wicket of Fatima Sana for nine to end with figures of 2-40.
Baig was run out for nine off the last ball of the innings.
