Liverpool closed the gap on leaders Manchester City with victory over West Ham, while Chelsea tightened their grip on third place in Saturday's Premier League action.

The Blues saw off Burnley 4-0 at Turf Moor, a scoreline that was matched by Aston Villa in their statement victory against Southampton.

Newcastle United, Crystal Palace and Brentford also picked up wins, but it was a bad start to life under new management for Leeds in their early kick-off against Leicester City.

Following another eventful day of Premier League action, Stats Perform delves into the key Opta facts from each of the games.

Leeds United 0-1 Leicester City: New manager, same Leeds

Jesse Marsch's first game as Leeds boss ended in defeat to Leicester as United fell to a fifth successive league loss for the first time since April 2015, when they were in the Championship.

Leeds have failed to score in three straight league matches for the first time in a year, this despite registering 19 shots in their latest blank against Leicester.

United's expected goals (xG) return of 1.95 is their highest without scoring in a league game since June 2020, and the familiar failings were also on show at the other end.

Harvey Barnes' second-half winner means Leeds have gone 13 league games without a clean sheet, their longest-such run since 14 without a shutout ending in August 2016.

This was the fifth straight league game Barnes has scored against Leeds – four of those while playing for Leicester and one for West Brom, making them his favourite opponent.

Aston Villa 4-0 Southampton: Coutinho's home comforts

Villa are firmly back on track after registering back-to-back victories under Steven Gerrard for the first time since his opening two games in charge in November.

The Villans put four unanswered goals past Southampton at Villa Park for their biggest Premier League win since thrashing Liverpool 7-2 in October 2020.

Barcelona loanee Philippe Coutinho once again played a big part in the victory by scoring one and assisting another for Douglas Luiz.

Coutinho has now been directly involved in six goals in his first four home league games for Villa, scoring three of his own and setting up as many.

Ollie Watkins had earlier opened the scoring with his 21st Premier League strike since the start of the 2020-21 season, while Danny Ings added to his two assists with Villa's fourth goal.

Newcastle United 2-1 Brighton and Hove Albion: Fraser helps end Magpies' duck against Seagulls

For a while things looked incredibly bleak for Newcastle, even after their big-money takeover, but they now find themselves seven points above the relegation zone.

The Magpies held off Brighton to make it eight Premier League games without defeat – no team is on a better such run – with five of those matches ending in victory.

Ryan Fraser opened the scoring to make it two goals in five Premier League outings, matching his tally from his previous 70 appearances, before setting up Fabian Schar.

That was the earliest United have scored twice in a Premier League home game since January 2007 and, despite Lewis Dunk's header, Eddie Howe's side saw out the win.

It marks the first time Newcastle have defeated Brighton in the Premier League in their 10th such encounter, having previously failed to so much as score against them at home.

Norwich City 1-3 Brentford: Bees buzzing thanks to Toney treble

After a run of eight Premier League games without a win, Brentford bolstered their survival ambitions with a well-earned victory away at bottom side Norwich.

Ivan Toney was the hero for the Bees with three goals, two of those from the penalty spot, making Brentford the 40th different team to boast a hat-trick scorer.

The Brentford striker now has nine Premier League goals for the season, each of those coming via his right foot.

Teemu Pukki scored a consolation but it was another miserable day for Norwich, whose goal difference of -42 is the worst at this stage since Derby County in 2007-08 (-44).

Not that it will matter a great deal in the grand scheme of things, but Brentford are the first team Pukki has scored home and away against in a single Premier League season.

Wolves 0-2 Crystal Palace: Shaky Wanderers lose again

Wolves' European hopes suffered another blow as they fell to a third successive Premier League defeat, as many as they lost in their previous 13.

Bruno Lage's out-of-form side have now conceded six goals in their last four league games, after shipping just five in 12 before that.

Jean-Philippe Mateta came up with the breakthrough from close range for his fourth goal in eight Premier League starts, and Wilfried Zaha doubled Palace's lead from the penalty spot.

Ivory Coast international Zaha has now been directly involved in 83 goals in the competition, the joint-ninth best total for an African player, level with Nwankwo Kanu.

With this latest loss, it is the first time Wolves have lost three games in a row against Palace in their entire league history.

Burnley 0-4 Chelsea: Blues cruise at Turf Moor

It was business as usual for Chelsea as they won for a third Premier League game running without conceding in what proved to be a straightforward victory at lowly Burnley.

The Blues scored all four of their goals in the second half as they enjoyed their biggest away league win since October 2018 when also beating Burnley by the same scoreline.

This was the biggest margin of victory for an away side in a game that was goalless at half-time since Tottenham beat Aston Villa 4-0 in December 2012.

Reece James started the scoring and in the process became the first defender from Europe's top five leagues to both score and assist five goals this term in all competitions.

Kai Havertz also netted twice before Christian Pulisic added some gloss to the scoreline – his fourth goal at Turf Moor, matching a record for an away player set by Tottenham's Harry Kane.

Liverpool 1-0 West Ham: Reds roll on thanks to Mane

Sadio Mane's first-half goal made it seven wins in a row for Liverpool in the Premier League, their best such streak since a run of 18 when they claimed the title two years ago.

That close-range finish was Mane's 12th of the season in the league, nine of those coming at Anfield – no player has scored more home goals in the division this season.

Trent Alexander-Arnold played the ball into the box for Mane's goal for his 16th assist in all competitions this term, more than he has ever registered in a single campaign.

Liverpool were not at their best and that was particularly true of Mohamed Salah, who failed to score from six shots – only against Stoke in April 2018 (seven) has he fared worse.

Incredibly, Virgil van Dijk has never been on the losing side for Liverpool in 60 Premier League home games at Anfield, setting a new record in that regard.

Liverpool will monitor the fitness of Diogo Jota ahead of their EFL Cup final against Chelsea on Sunday, but Reds assistant manager Pep Ljinders confirmed Roberto Firmino is out of contention.

Jota and Firmino suffered knocks against Inter in the first leg of their Champions League last-16 clash on February 16, and subsequently missed Premier League wins over Norwich City and Leeds United.

Liverpool manager Jurgen Klopp conceded that the pair were both doubts for the final before the Leeds' game, in which fellow attackers Mohamed Salah and Sadio Mane netted two goals each.

Ljinders provided another update on the duo on Friday as he offered faint hope that Jota could play some part against Thomas Tuchel's men.

"Bobby [Firmino] we will have to see in the next two days, he's pushing himself really hard, but he will not be available for the final, to reach the squad," Ljinders said.
 
"We hope he will be back really soon because you all see and feel how important he is for our way of playing. [We are] happy that he's pushing himself, hopefully he's soon back.
 
"Jota, there has been so far no reaction on the things he did – the straight-line running, the little ball work he did, so that's a good sign. He isn't ruled out but it will still be a challenge."

The Reds will be hoping Jota can beat the clock to feature, given he could become only the second ever Liverpool player to score in each of the quarter-final, semi-final and final of the competition in a single season (replays included), after Kenny Dalglish in 1980-81.

Nevertheless, Klopp's side will be left in capable hands even without Jota, with new boy Luis Diaz, Salah and Mane to call upon in the frontline.

Mane has scored eight goals against Chelsea in all competitions, only netting more in his career in England against Crystal Palace (13), while Salah leads the Premier League scoring charts with 19 this term.

The Senegal international, however, is yet to score an EFL Cup goal for the Reds in three previous appearances for them in the competition, the most recent of which was against Chelsea in the 2018-19 third round.

Kylian Mbappe to Real Madrid has often felt like a never-ending transfer saga, but it appears a resolution might now be in sight.

Los Blancos are apparently confident of getting the Paris Saint-Germain star in 2022 even though their performance did not impress him in the Champions League.

However, Madrid do have a back-up plan.

TOP STORY – MADRID CONFIDENT ON MBAPPE BUT MANE IS PLAN B

Real Madrid believe they will win the battle to sign Kylian Mbappe on a free transfer from Paris Saint-Germain in 2022.

Carlo Ancelotti's side are preparing to announce the deal at the end of the season, according to Goal.

However, should their efforts to sign Mbappe or Erling Haaland fail, Madrid have a back-up plan: Fichajes claims they will submit an offer for Sadio Mane.

ROUND-UP

- Arsenal are interested in signing Joao Felix from Atletico Madrid, according to television show El Chiringuito.

- Manchester United have been quoted €75million (£62.5m) for RB Leipzig star Christopher Nkunku, Bild says.

- Meanwhile, United striker Edinson Cavani is ready to listen to an offer to join Botafogo when his contract expires, Goal claims.

- According to Sport, Tottenham have submitted the firmest offer to sign Paulo Dybala from Juventus, but Barcelona and Inter are also interested.

- Milan are resigned to losing Franck Kessie after this season and could replace him with Renato Sanches, Tuttosport says.

- UEFA has decided to move the Champions League final from St Petersburg, according to the BBC. The game could be held in London.

Borussia Dortmund striker Erling Haaland and Paris Saint-Germain superstar Kylian Mbappe remain arguably the two most sought-after players in world football.

The pair, who boast 43 goals in 50 games between them this season, have inevitably been linked with an array of Europe's top clubs ahead of the next transfer window.

And it may well be that one replaces the other at PSG in the coming months.

TOP STORY – HAALAND AMONG PSG TARGETS

L'Equipe reports that Haaland is one of a handful of players being eyed up by PSG, who are growing increasingly concerned that Mbappe will join Real Madrid on a free transfer.

However, the Ligue 1 giants are said to have made tying down Mbappe to fresh terms their main priority between now and the end of the season.

Should the World Cup winner depart, PSG would then have to see off competition from the likes of Madrid, Barcelona and several Premier League teams for Haaland's signature.

ROUND-UP

- Harry Kane failed in his attempt to force through a move from Tottenham last year, but Fabrizio Romano claims the striker is now happy to stay under Antonio Conte.

- After further enhancing his reputation by firing Senegal to Africa Cup of Nations glory, Goal reports that Sadio Mane is open to leaving Liverpool ahead of next season.

- According to Fabrizio Romano, Madrid are eager to finalise terms with Luka Modric over a new deal that will run through for an additional season until the end of 2022-23.

- Ajax are prepared to tempt Barcelona into allowing Sergino Dest to return to the club by offering Nicolas Tagliafico in exchange. That is according to reports from Spain.

- Calciomercato reports that Milan are close to agreeing a four-year extension for full-back Theo Hernandez, who is currently due to be out of contract in July 2024.

Senegal hero Sadio Mane has dedicated the side's Africa Cup of Nations triumph to Aliou Cisse who he labelled "the most criticized head coach I've ever seen in my life".

The Liverpool forward went from zero to hero when he netted the decisive spotkick as Senegal defeated Egypt 4-2 in a shootout following a 0-0 draw in Sunday's final where Mane missed a seventh-minute penalty.

Mane's penalty not only clinched Senegal's first-ever continental crown but it was a personal moment of redemption, having missed a decisive spotkick in the 2017 quarter-finals against Cameroon.

But the 29-year-old singled out head coach Cisse, who has 35 caps for Senegal before taking over as head coach in 2015, to dedicate the triumph.

"I know that the Senegalese people have suffered a lot but I dedicate this trophy to Aliou Cisse," Mane told reporters, having noted the criticism of the Lions of Teranga boss in the lead-up to the game. "If you knew what he did for the team."

Mane added: "When I missed the penalty first I thought of Aliou Cisse.. When I scored the last penalty, I immediately thought of Aliou Cisse."

Cisse, who was a runner-up at AFCON in 2002 during his playing days, praised the current generation headlined by Mane and Chelsea goalkeeper Edouard Mendy who saved Mohanad Lasheen's spotkick to set up his teammate's moment of glory.

"It really proves the mental strength of this generation," Cisse said. "We're African champions.

"It's been long, it's been hard, and there have been complicated moments, but we never gave up.

"This was a hard match too; we missed the penalty, and there were other chances we weren't able to take, but the boys never abandoned the task.

"We are very happy to dedicate the victory to the Senegalese people because from independence until now we have been chasing this first win in this competition."

Sadio Mane made up for an earlier penalty miss with the decisive spot-kick as Senegal claimed their first Africa Cup of Nations title with a 4-2 shoot-out win over Egypt.

The Lions of Teranga were beaten in the 2019 final by Algeria, but they belatedly got their hands on the trophy at Olembe Stadium on Sunday with a dramatic shoot-out victory after a largely dour goalless 120 minutes.

Mane saw an early penalty saved by Mohamed Abou Gabal and he was fortunate to still be on the pitch for the spot-kicks having avoided a second yellow card for a clear dive.

The Liverpool forward had the last laugh, though, powering low past Abou Gabal after Edouard Mendy had kept out Mohanad Lasheen's tepid effort from 12 yards to send the travelling Senegal fans into raptures.

The Africa Cup of Nations final on Sunday is the match that many observers had wished to see and that Jurgen Klopp had perhaps hoped to avoid.

Senegal, runners-up to Algeria two years ago, have the chance to get their hands on the trophy for the first time at Olembe Stadium. Standing in their way are Egypt, seeking a record-extending eighth African title and their first since 2010.

It will also be the much-anticipated meeting of Sadio Mane and Mohamed Salah, the Liverpool stars looking to cement their status as the finest players from the continent.

Reds manager Klopp could be forgiven for wishing both teams had been knocked out sooner so he could have Mane and Salah back on Merseyside, but he described it as a "great achievement" to see both players competing for the trophy.

"Now it's obviously not so easy because one will definitely be really happy after and the other one much less so, but both have a good chance to achieve something really big," he said.

Salah did not need to take a penalty in the semi-final shoot-out with Cameroon, who beat them in their last final appearance in 2017, as the host nation missed three kicks in a row to send the Pharoahs through.

This will be a record-equalling ninth AFCON final for Egypt and their first meeting with Senegal in this competition since the 2006 semi-finals, which they won 2-1 en route to lifting the trophy. Overall, the head-to-head record stands at two wins each.

Yet Senegal have won 11 matches over the past three AFCON tournaments, more than any other team, and kept the most clean sheets (12) in that time. That form has continued in 2022: they have won four of their six games, scoring nine times and conceding just twice, hitting three in their quarter-final and semi-final wins while Egypt have needed extra time or penalties in three straight matches.

Mane's influence has helped them become clinical: at these finals, Senegal have scored nine goals from 81 attempts, a shot conversion rate bettered only by Cameroon (11 goals from 91 shots). Egypt, with four goals from 76 efforts, have the lowest conversion rate among any of the teams to reach the knockout phase.

Egypt coach Carlos Queiroz, however, is not feeling concerned.

"Words like fear have been erased from our dictionary," he said. "In our football dictionary, there is the word 'respect'. We have great respect for our opponents and their players, because they are performing well and scoring goals. But we are ready."

For Senegal counterpart Aliou Cisse, a losing finalist as a player and coach, his players' mental fortitude is the most important thing they have.

"We know it will be a very difficult final," he said. "I congratulate my players because we have come a long way. They had the right mentality. I can assure you that the best quality of a player in the national team is having the right mentality."

Players to watch

Senegal: Sadio Mane

With a goal and an assist in the semi-final win over Burkina Faso, Mane has been directly involved in nine (six scored, three assisted) of Senegal's past 14 goals at the AFCON. He will be looking to register a goal involvement in four consecutive matches in this competition for the first time.

The pressure is firmly on Mane to lead the top-ranked team in Africa to the trophy for the first time.

Egypt: Mohamed Salah

Salah has only scored twice at these finals, excluding the shoot-out win over Ivory Coast, but his influence extends beyond goals of his own: since his competition debut in January 2017, he has been directly involved in 68 shots at goal for Egypt (41 shots, 27 chances created). Only Tunisia's Wahbi Khazri (70 – 40 shots, 30 chances created) has been involved in more in this time.

"Salah is not only the best player in Egypt but a world-class player and his presence is a boost for the other members of the team," said Egypt assistant coach Diaa al-Sayed. "He is a guide and a leader. His presence is so crucial for us. He came here to win and we hope he will."

Liverpool manager Jurgen Klopp is excited for either Sadio Mane or Mohamed Salah to "achieve something really big" after reaching the final of the Africa Cup of Nations.

Senegal and Egypt will face each other for the right to be crowned champions of Africa on Sunday at the Olembe Stadium in Yaounde.

Mane scored the third goal in Senegal's 3-1 semi-final defeat of Burkina Faso to take his personal tally for the tournament to three, while Salah helped Egypt to a 3-1 penalties win over hosts Cameroon after a 0-0 draw on Thursday.

Klopp has previously been accused of disrespecting the AFCON on several occasions. In 2020, he called the tournament's move from June to January a "catastrophe", then, in November last year, he referred to it as a "little tournament" before claiming he meant the comment in an "ironic" manner.

Now, with two of his best players set to grace the final, Klopp is thrilled to see both with the chance to create history for their nations.

Asked if he had arranged something of a viewing party with the squad, Klopp said: "I have nothing planned yet.

"I didn't think about it, but we've followed it pretty closely. It's a great achievement for both. Naby [Keita] played exceptional in the tournament, too.

"So far it's been a really successful tournament for our boys. It's exciting, but not so easy because one will be really happy after, one much less so.

"Both have a good chance to achieve something really big."

Speaking to the media ahead of Sunday's FA Cup fourth-round clash with Cardiff City, attention soon turned to when Salah and Mane will be available for the Reds again.

Klopp thinks there is a chance both could be available for Thursday's Premier League visit of Leicester City, though he accepts whoever loses in Sunday's final has a better chance of that.

"I think they will be available but we will see," Klopp added. "If one wins they'll probably fly back to home country for a celebration, that's how it is.

"I think Tuesday or Wednesday [is the] latest the winner will be back, the other one slightly earlier.

"Then I have to talk to them. One thing is they have rhythm, played quite a few games, but I have to speak to them."

Senegal reached a second consecutive Africa Cup of Nations final as goals from Abdou Diallo, Idrissa Gueye and Sadio Mane secured a 3-1 win over Burkina Faso on Wednesday. 

Aliou Cisse's side were denied a first AFCON title by Algeria back in 2019, but they will have another chance to get their hands on the trophy against either Cameroon or Egypt in Sunday's decider after edging their semi-final.

Senegal thought they had been awarded a penalty deep into first-half stoppage, but the VAR came to Burkina Faso's rescue with referee Bamlak Tessema Weyesa overturning his initial decision after replays showed Gueye's shot had hit Edmond Tapsoba's stomach and not his hand.

The Lions of Teranga deservedly broke the deadlock in the 70th minute, however, when Paris Saint-Germain defender Diallo spun on the six-yard box and fired a crisp strike past substitute goalkeeper Sofiane Ouedraogo. 

And Senegal doubled their advantage six minutes later when Gueye slotted home from inside the penalty area after being teed up by Mane.

Ibrahim Toure pulled one back for Burkina Faso with an improvised finish with his knee in the 82nd minute, but Mane put the game to bed five minutes later with a sublime breakaway goal.

Sadio Mane will be hoping to fire Senegal back into the Africa Cup of Nations final when they take on Burkina Faso in the semi-finals on Wednesday. 

Senegal's hopes of winning a first AFCON title were dashed by Algeria back in 2019 but they are looking to become the first team since Egypt in 2010 to reach successive finals – and this time they will be desperate to go one better and lift the trophy.

History appears to be in their favour too. That loss to Algeria is the Lions of Teranga's only defeat in their past six knockout games in the competition, and they have only conceded two goals in that span.  

Furthermore, they are unbeaten in their two previous AFCON meetings with Burkina Faso, though both of those came in the group stage. 

But Burkina Faso are no strangers to this stage of the competition. They have made the final four for the fourth time in their history and the third time in the past five editions – this despite not even qualifying for the 2019 tournament. 

Kamou Malo's team did well to upset Tunisia in the quarter-finals, though they will be without their goalscorer Dango Ouattara after his red card in the 82nd minute of their 1-0 victory. 

Malo said: "I think that at this level of competition, there are no limits. Don't worry, we all have the same goal, which is to win this trophy. 

"As for my desire to go all the way in this competition, yes, there is no doubt about that. We are ready to be extremely competitive to go to the end of this competition." 

Burkina Faso's hopes of pulling off another upset will rely heavily on keeping Mane at bay. 

The Liverpool star may have just two goals in Cameroon, but only Mohamed Salah (14), Sofiane Boufal (11) and Ibrahim Sangare (eight) have outdone his seven open-play key passes in the competition.

One to watch: Gustavo Sangare (Burkina Faso) 

With Ouattara absent due to suspension, Sangare will be expected to step up on the opposite wing. 

He has already been important for Burkina Faso, scoring the opening goal of the tournament in a 2-1 loss to hosts Cameroon in the group stage – no one in the squad has found the net on more than one occasion in the competition. 

But it is his ingenuity that the Stallions could use more than anything. Only Zakaria Sanogo and Blati Toure (four each) have created more chances from open play for Burkina Faso than Sangare's three, while the Quevilly winger has been involved in a team-high three goal-ending sequences. 

He has proven to be a real threat with the ball at his feet and could help thwart Senegal and send the underdogs into the showpiece. 

The Africa Cup of Nations is heating up in the quarter-final stage, with Sunday's encounters two of the more fascinating of the round on paper.

After edging past the Ivory Coast in the round of 16 on penalties, Egypt take on Morocco where two stars of world football, Mohamed Salah and Achraf Hakimi, go head-to-head.

Senegal will play Equatorial Guinea for just the second time at the AFCON, with the latter winning the previous such game 2-1 in the group stages in 2012.

Stats Perform takes a look at both games as we get closer to the business end of this year's tournament.

Egypt v Morocco (15:00 GMT)

This will be the seventh AFCON encounter between these teams, with Morocco winning three of the previous six (D1 L2), although Egypt won the most recent encounter in the 2017 quarter-finals.

The Pharaohs have won each of their past four quarter-final matches at the AFCON, having progressed in just one of their previous five.

Morocco have won six of their past eight matches in this competition (D2), scoring in every game in this run, although they are looking to reach the semi-finals of the competition for the first time since finishing runners-up to Tunisia in 2004.

There have been a number of tight games at this year's tournament and that may be the case again here. Egypt have only conceded seven goals in their 20 games at the AFCON since 2010 (W14 D3 L3), keeping 14 clean sheets.

Morocco's Romain Saiss has accumulated an expected goals (xG) tally of 1.99 from his five attempts in the competition, the highest xG of any player who is yet to score this year.

One to watch: Achraf Hakimi (Morocco)

The Paris Saint-Germain right-back had been having a relatively quiet AFCON up until the knockout stages, only to put in a top-quality performance to help his nation topple Malawi in the round of 16.

His excellent free-kick in the 2-1 win was just one of his five attempts at goal, four of which were on target. Hakimi had only taken three shots in total in his three group stage appearances. His partnership with Imran Louza – who made five key passes against Malawi, more than anyone else – on the right could be vital, with Salah likely occupying their team-mates on the other side.

Senegal v Equatorial Guinea (19:00 GMT)

It was a horrible sight to see Sadio Mane crash to the floor after a head collision with Cape Verde goalkeeper Vozinha in their round-of-16 tie, despite picking himself up to score the winner moments later.

Whether the Liverpool man is fit to play remains to be seen, but it could be crucial as he has scored 44 per cent of Senegal's goals (seven of 16, excluding own goals) at the AFCON since 2017, while none of his team-mates have scored more than once in this time.

Senegal have progressed from three of their past five quarter-final matches at the AFCON, while they are looking to reach the semi-finals in consecutive tournaments for the first time.

Equatorial Guinea have lost just one of their most recent five AFCON games (W2 D2), keeping four clean sheets and conceding just once.

Since the start of the 2017 tournament, Senegal have won more games (nine) and kept more clean sheets (12) than any other team.

One to watch: Saul Coco (Equatorial Guinea)

The Las Palmas defender was a rock at the back for his country in the round-of-16 clash with Mali, making seven clearances, more than twice as many as any of his team-mates, as well as three blocks. He also scored his penalty in the shoot-out and may need that calm temperament when facing Senegal's pacey attack.

He is also part of an Equatorial Guinea defence that has conceded just once in the tournament, despite facing an overall xG of 4.2.

Senegal have been defended by Confederation of African Football (CAF) medical doctor Dr. Thulani Ngwenya for their handling of Sadio Mane's head injury against Cape Verde.

Mane received a nasty blow to the head in a collision with opposition goalkeeper Vozinha – who was sent off after a VAR review – in Tuesday's Africa Cup of Nations last-16 tie.

The Liverpool forward was given treatment on the field but was allowed to stay on and subsequently curled in a brilliant opener for Senegal, who went on to win 2-0.

However, Mane collapsed to the ground when celebrating his goal and was taken off shortly afterwards before being assessed at hospital.

He later took to social media to assure worried supporters that "all is well", but brain injury association Headway criticised Senegal for allowing Mane to play on after the collision.

"On the face of it, this seems to be yet another example of football putting results ahead of player safety," said Luke Griggs, deputy chief executive of Headway.

"This was a sickening collision that clearly left both players in enough distress for a concussion to have surely been considered a possibility at the very least.

"At that point, the principle of 'if in doubt, sit it out!' should have resulted in Mane being substituted without another ball being kicked."

Griggs added: "This is now a real test of leadership for CAF and world governing body FIFA – particularly if Senegal declare Mane fit for Sunday's quarter-final.

"If football wants to be taken seriously when it comes to concussion, it simply must take action to enforce and strengthen its protocols."

But Dr. Ngwenya insisted Mane is in good hands with the Senegal medical team, who remain in dialogue with Premier League side Liverpool.

"We have a very capable medical team. Senegal have two team doctors, who are highly commended," Dr. Ngwenya is quoted as saying by Sky Sports.

"I know the team doctors are responsible, so they communicate with the club and I understand that they have actually communicated with Liverpool.

"What I know is that after taking Mane for further investigations, we scanned the head and there was no structural damage, but that does not rule out concussion. 

"I'm confident that my colleagues are taking care of the player and the player was in good spirits when I saw him in the hospital."

Dr. Ngwenya added: "I've heard people say, 'why wasn't he removed from the game?' The medical assessment is based on what you see and assess at that particular time. 

"The medical team spent quite a significant amount of time assessing Mane.

"It might have been during the assessment the medical team came to a decision it was just a head collision, not concussion because they couldn't pick up anything that was concussion.

"We need to give the benefit of the doubt to them because you can make an assessment at the time and then two minutes later it's different. 

"But when I went in there were features of concussion, hence it was easy for me to actually make that call to say we need to remove the player out of the game.

"The player is not capacitated to make a decision because they are confused, so it's you as a doctor that needs to make a decision on their behalf."

Mane posted an image of himself back in the gym on his personal Instagram account on Thursday, accompanied by the caption "recovering".

Despite potentially suffering from concussion after the sickening blow, he has not been ruled out of Senegal's quarter-final against Equatorial Guinea on Sunday.

"I'm not sure if he will be available for the next match. When you look at the protocols, I don't know whether he will be ready. I can't make that assessment," Ngwenya said.

"That judgement can only be made by the team doctors that are managing him on a daily basis."

Senegal have been criticised by brain injury association Headway for their handling of Sadio Mane's head injury in the Africa Cup of Nations win over Cape Verde.

Liverpool star Mane received a nasty blow to the head in a collision with Cape Verde goalkeeper Vozinha, who was sent off after a VAR review of the incident, during Tuesday's last-16 tie.

Mane received treatment on the field but was allowed to stay on and subsequently curled in a brilliant opener for Senegal, who went on to win 2-0.

The forward was taken off shortly after and was then taken to hospital for further assessment.

A photograph – posted on the official Africa Cup of Nations Twitter account – revealed that Vozinha visited Mane in hospital after the game.

Sharing the photo on Instagram, Mane told his 9.1million followers: "All is well. Thank you all for the messages."

However, brain injury association Headway have criticised how Senegal allowed Mane to play on following the collision.

"On the face of it, this seems to be yet another example of football putting results ahead of player safety," said Luke Griggs, deputy chief executive of Headway, in a statement released on the association's website.

"This was a sickening collision that clearly left both players in enough distress for a concussion to have surely been considered a possibility at the very least.

"At that point, the principle of 'if in doubt, sit it out!' should have resulted in Mane being substituted without another ball being kicked.

"The image of the player collapsing on the ground and having to be helped from the pitch after scoring his goal should tell you everything you need to know about the impact and the effect it had had on his brain.

"Yet again, the desire to win is seen as being worth serious risks to players' health. It is simply shocking that this continues to happen.

"This is now a real test of leadership for The Confederation of African Football (CAF) and world governing body FIFA – particularly if Senegal declare Mane fit for Sunday's quarter-final.

"If football wants to be taken seriously when it comes to concussion, it simply must take action to enforce and strengthen its protocols."

In the Premier League, concussion substitutes have been introduced that enable teams to take a player off if they have sustained a head injury, without giving up one of their three allocated changes.

Neither FIFA nor CAF had commented on the incident at the time of publication.

Sadio Mane scored a sublime goal to send Senegal into the Africa Cup of Nations quarter-finals at the expense of Cape Verde, who had two players sent off in their 2-0 defeat.

Tuesday's encounter at Kouekong Stadium, the first between these sides in the continental competition, swung the way of Senegal when Patrick Andrade was dismissed after 21 minutes following a VAR check on a foul on Pape Gueye.

Cape Verde, who scraped into the knockout phase as one of the top third-placed teams in the groups, proceeded to contain Aliou Cisse's side to good effect and keep alive their chances of reaching the last eight for the first time since 2013.

However, another VAR intervention just before the hour mark left them with an arduous task, goalkeeper Vozinha eventually being shown a red card – while sitting on the sidelines for treatment – after a nasty clash of heads with Mane when the Liverpool forward was chasing a bouncing ball on the edge of the box.

It was a moment of brilliance from Mane that finally broke the deadlock as he curled a finish in off the crossbar from 18 yards out following a corner, although the goal only stood after another VAR review into a possible foul in the build-up.

Mane, apparently still feeling the effects of his collision with Vozinha, was substituted seven minutes later and could now be a doubt for the last-eight meeting with either Mali or Equatorial Guinea on Sunday.

Senegal, who are the only side at the 2022 finals yet to concede a goal, made certain of a place in the next round through Bamba Dieng's composed finish as they counter-attacked in injury time.

Liverpool are proving that they are not just reliant on Mohamed Salah and Sadio Mane, according to assistant manager Pep Lijnders.

Jurgen Klopp's side are having to do without two of their star attackers, with Salah and Mane on international duty at the Africa Cup of Nations with Egypt and Senegal respectively.

Naby Keita is also featuring at the tournament, with the midfielder a talisman for Guinea, who like Senegal have progressed from Group B. Salah's Egypt will guarantee their qualification from Group D with a win over Sudan on Wednesday.

The tournament runs until February 6. Senegal were runners-up in 2019 while Egypt are the most successful team in AFCON history with seven titles, and both are fancied to go far this time around in Cameroon.

Liverpool have been without the trio since just after a draw with Chelsea on January 2, and though they subsequently beat Shrewsbury Town in the FA Cup, the absence of Mane and the Premier League's leading scorer Salah was particularly felt in a 0-0 draw with 10-man Arsenal at Anfield in the first leg of the EFL Cup semi-final on January 13.

The Gunners had Granit Xhaka sent off midway through the first half yet Liverpool mustered only one effort on target, with that shot coming in stoppage time, after Takumi Minamino had spurned a glorious chance.

The Reds bounced back with a routine 3-0 win over Brentford on Sunday, with Liverpool having 27 shots (13 on target) and controlling 68 percent of the possession.

Liverpool had 3.1 expected goals against Brentford, the joint-fourth highest total for them in a league game this season, while they have only managed more shots in one top-flight fixture (against Leeds United in September), with their shots-on-target total the most in a single match.

Asked ahead of the second leg against Arsenal how pleased he was with Liverpool's reaction to being without such key players, Lijnders told a news conference: "We did it before. One of the most memorable games [the 4-0 Champions League win over Barcelona in 2019] was without a few of them [Salah and Roberto Firmino].

"When we have our squad, we knew that we needed to have different weapons, create goals from everywhere, dribbles from everywhere, attacks from everywhere, not just based on counter-attacks or the speed of these two boys.

"They are our front line but what I like is we don't just have one weapon, we have so many different ways to attack. How we are evolving as a team, developing with our positional game, it's important and we really like it."

Alex Oxlade-Chamberlain stepped up on Sunday, scoring Liverpool's second and playing three key passes, second only to Fabinho (four), though the midfielder will not be available against his former club on Thursday due to an ankle injury sustained against Brentford.

"I spoke with him and he feels okay, it's not that bad," Lijnders explained. "He's hoping that he will make the weekend. Tomorrow will be way too soon. We will assess that day by day."

While Liverpool beat Brentford, Arsenal were not in action on Sunday, with the Premier League having granted the Gunners' request to postpone the north London derby clash with Tottenham due to a COVID-19 case within the squad, though injuries and players away at AFCON were also cited as a reason.

"We had our own experience with this, it's really difficult to judge from the outside," said Lijnders, who had to take charge of the Chelsea clash this month when Klopp was self-isolating due to COVID-19.

"We saw that with our situation. I fully respect the submissions because I trust 100 percent the medical department of each Premier League club. I think this is the most important, the trust in these decisions."