Senegal have been defended by Confederation of African Football (CAF) medical doctor Dr. Thulani Ngwenya for their handling of Sadio Mane's head injury against Cape Verde.

Mane received a nasty blow to the head in a collision with opposition goalkeeper Vozinha – who was sent off after a VAR review – in Tuesday's Africa Cup of Nations last-16 tie.

The Liverpool forward was given treatment on the field but was allowed to stay on and subsequently curled in a brilliant opener for Senegal, who went on to win 2-0.

However, Mane collapsed to the ground when celebrating his goal and was taken off shortly afterwards before being assessed at hospital.

He later took to social media to assure worried supporters that "all is well", but brain injury association Headway criticised Senegal for allowing Mane to play on after the collision.

"On the face of it, this seems to be yet another example of football putting results ahead of player safety," said Luke Griggs, deputy chief executive of Headway.

"This was a sickening collision that clearly left both players in enough distress for a concussion to have surely been considered a possibility at the very least.

"At that point, the principle of 'if in doubt, sit it out!' should have resulted in Mane being substituted without another ball being kicked."

Griggs added: "This is now a real test of leadership for CAF and world governing body FIFA – particularly if Senegal declare Mane fit for Sunday's quarter-final.

"If football wants to be taken seriously when it comes to concussion, it simply must take action to enforce and strengthen its protocols."

But Dr. Ngwenya insisted Mane is in good hands with the Senegal medical team, who remain in dialogue with Premier League side Liverpool.

"We have a very capable medical team. Senegal have two team doctors, who are highly commended," Dr. Ngwenya is quoted as saying by Sky Sports.

"I know the team doctors are responsible, so they communicate with the club and I understand that they have actually communicated with Liverpool.

"What I know is that after taking Mane for further investigations, we scanned the head and there was no structural damage, but that does not rule out concussion. 

"I'm confident that my colleagues are taking care of the player and the player was in good spirits when I saw him in the hospital."

Dr. Ngwenya added: "I've heard people say, 'why wasn't he removed from the game?' The medical assessment is based on what you see and assess at that particular time. 

"The medical team spent quite a significant amount of time assessing Mane.

"It might have been during the assessment the medical team came to a decision it was just a head collision, not concussion because they couldn't pick up anything that was concussion.

"We need to give the benefit of the doubt to them because you can make an assessment at the time and then two minutes later it's different. 

"But when I went in there were features of concussion, hence it was easy for me to actually make that call to say we need to remove the player out of the game.

"The player is not capacitated to make a decision because they are confused, so it's you as a doctor that needs to make a decision on their behalf."

Mane posted an image of himself back in the gym on his personal Instagram account on Thursday, accompanied by the caption "recovering".

Despite potentially suffering from concussion after the sickening blow, he has not been ruled out of Senegal's quarter-final against Equatorial Guinea on Sunday.

"I'm not sure if he will be available for the next match. When you look at the protocols, I don't know whether he will be ready. I can't make that assessment," Ngwenya said.

"That judgement can only be made by the team doctors that are managing him on a daily basis."

Senegal have been criticised by brain injury association Headway for their handling of Sadio Mane's head injury in the Africa Cup of Nations win over Cape Verde.

Liverpool star Mane received a nasty blow to the head in a collision with Cape Verde goalkeeper Vozinha, who was sent off after a VAR review of the incident, during Tuesday's last-16 tie.

Mane received treatment on the field but was allowed to stay on and subsequently curled in a brilliant opener for Senegal, who went on to win 2-0.

The forward was taken off shortly after and was then taken to hospital for further assessment.

A photograph – posted on the official Africa Cup of Nations Twitter account – revealed that Vozinha visited Mane in hospital after the game.

Sharing the photo on Instagram, Mane told his 9.1million followers: "All is well. Thank you all for the messages."

However, brain injury association Headway have criticised how Senegal allowed Mane to play on following the collision.

"On the face of it, this seems to be yet another example of football putting results ahead of player safety," said Luke Griggs, deputy chief executive of Headway, in a statement released on the association's website.

"This was a sickening collision that clearly left both players in enough distress for a concussion to have surely been considered a possibility at the very least.

"At that point, the principle of 'if in doubt, sit it out!' should have resulted in Mane being substituted without another ball being kicked.

"The image of the player collapsing on the ground and having to be helped from the pitch after scoring his goal should tell you everything you need to know about the impact and the effect it had had on his brain.

"Yet again, the desire to win is seen as being worth serious risks to players' health. It is simply shocking that this continues to happen.

"This is now a real test of leadership for The Confederation of African Football (CAF) and world governing body FIFA – particularly if Senegal declare Mane fit for Sunday's quarter-final.

"If football wants to be taken seriously when it comes to concussion, it simply must take action to enforce and strengthen its protocols."

In the Premier League, concussion substitutes have been introduced that enable teams to take a player off if they have sustained a head injury, without giving up one of their three allocated changes.

Neither FIFA nor CAF had commented on the incident at the time of publication.

Sadio Mane scored a sublime goal to send Senegal into the Africa Cup of Nations quarter-finals at the expense of Cape Verde, who had two players sent off in their 2-0 defeat.

Tuesday's encounter at Kouekong Stadium, the first between these sides in the continental competition, swung the way of Senegal when Patrick Andrade was dismissed after 21 minutes following a VAR check on a foul on Pape Gueye.

Cape Verde, who scraped into the knockout phase as one of the top third-placed teams in the groups, proceeded to contain Aliou Cisse's side to good effect and keep alive their chances of reaching the last eight for the first time since 2013.

However, another VAR intervention just before the hour mark left them with an arduous task, goalkeeper Vozinha eventually being shown a red card – while sitting on the sidelines for treatment – after a nasty clash of heads with Mane when the Liverpool forward was chasing a bouncing ball on the edge of the box.

It was a moment of brilliance from Mane that finally broke the deadlock as he curled a finish in off the crossbar from 18 yards out following a corner, although the goal only stood after another VAR review into a possible foul in the build-up.

Mane, apparently still feeling the effects of his collision with Vozinha, was substituted seven minutes later and could now be a doubt for the last-eight meeting with either Mali or Equatorial Guinea on Sunday.

Senegal, who are the only side at the 2022 finals yet to concede a goal, made certain of a place in the next round through Bamba Dieng's composed finish as they counter-attacked in injury time.

Liverpool are proving that they are not just reliant on Mohamed Salah and Sadio Mane, according to assistant manager Pep Lijnders.

Jurgen Klopp's side are having to do without two of their star attackers, with Salah and Mane on international duty at the Africa Cup of Nations with Egypt and Senegal respectively.

Naby Keita is also featuring at the tournament, with the midfielder a talisman for Guinea, who like Senegal have progressed from Group B. Salah's Egypt will guarantee their qualification from Group D with a win over Sudan on Wednesday.

The tournament runs until February 6. Senegal were runners-up in 2019 while Egypt are the most successful team in AFCON history with seven titles, and both are fancied to go far this time around in Cameroon.

Liverpool have been without the trio since just after a draw with Chelsea on January 2, and though they subsequently beat Shrewsbury Town in the FA Cup, the absence of Mane and the Premier League's leading scorer Salah was particularly felt in a 0-0 draw with 10-man Arsenal at Anfield in the first leg of the EFL Cup semi-final on January 13.

The Gunners had Granit Xhaka sent off midway through the first half yet Liverpool mustered only one effort on target, with that shot coming in stoppage time, after Takumi Minamino had spurned a glorious chance.

The Reds bounced back with a routine 3-0 win over Brentford on Sunday, with Liverpool having 27 shots (13 on target) and controlling 68 percent of the possession.

Liverpool had 3.1 expected goals against Brentford, the joint-fourth highest total for them in a league game this season, while they have only managed more shots in one top-flight fixture (against Leeds United in September), with their shots-on-target total the most in a single match.

Asked ahead of the second leg against Arsenal how pleased he was with Liverpool's reaction to being without such key players, Lijnders told a news conference: "We did it before. One of the most memorable games [the 4-0 Champions League win over Barcelona in 2019] was without a few of them [Salah and Roberto Firmino].

"When we have our squad, we knew that we needed to have different weapons, create goals from everywhere, dribbles from everywhere, attacks from everywhere, not just based on counter-attacks or the speed of these two boys.

"They are our front line but what I like is we don't just have one weapon, we have so many different ways to attack. How we are evolving as a team, developing with our positional game, it's important and we really like it."

Alex Oxlade-Chamberlain stepped up on Sunday, scoring Liverpool's second and playing three key passes, second only to Fabinho (four), though the midfielder will not be available against his former club on Thursday due to an ankle injury sustained against Brentford.

"I spoke with him and he feels okay, it's not that bad," Lijnders explained. "He's hoping that he will make the weekend. Tomorrow will be way too soon. We will assess that day by day."

While Liverpool beat Brentford, Arsenal were not in action on Sunday, with the Premier League having granted the Gunners' request to postpone the north London derby clash with Tottenham due to a COVID-19 case within the squad, though injuries and players away at AFCON were also cited as a reason.

"We had our own experience with this, it's really difficult to judge from the outside," said Lijnders, who had to take charge of the Chelsea clash this month when Klopp was self-isolating due to COVID-19.

"We saw that with our situation. I fully respect the submissions because I trust 100 percent the medical department of each Premier League club. I think this is the most important, the trust in these decisions."

Senegal failed to take advantage of their apparent superiority against Guinea as they were held to a 0-0 draw at the Africa Cup of Nations.

The Lions of Teranga reached the final of the 2019 tournament but are still awaiting their first AFCON title and better attacking play will be required for them to do so on the evidence of this Group B encounter.

Liverpool manager Jurgen Klopp was left to rue the absence of Senegal's Sadio Mane and Guinea's Naby Keita, as well as Mohamed Salah of Egypt, in their 0-0 EFL Cup draw with Arsenal on Thursday. But neither Mane nor Keita could provide the moment of magic to break the deadlock in Bafoussam, though it was not for lack of trying.

Guinea, for whom Keita played a game-high 18 passes in the opposition half, should have taken the lead in the 31st minute when Morgan Guilavogui shot straight at Seny Timothy Dieng after a counter-attack, while Mane created Senegal's best chance of the game in the 67th minute only for Bouna Sarr to skew hopelessly wide from close range.

Sarr's miss encapsulated a match in which the two teams combined for just three shots on target, though both should sail into the next round having each claimed four points from two games in a group with minnows Malawi and Zimbabwe.

Jurgen Klopp does not believe there is any team that would not miss Mohamed Salah and Sadio Mane, after Liverpool felt the duo's absence against Arsenal.

Salah and Mane, along with midfielder Naby Keita, are on international duty at the Africa Cup of Nations.

Mane scored a last-gasp winner on Monday for Senegal against Zimbabwe, and he and Guinea's Keita go head-to-head when their nations face off on Friday.

Salah, meanwhile, was kept quiet as Egypt slipped to a 1-0 loss to Nigeria in their opening group game. The forward, who has netted 23 times across all competitions this season for Liverpool, had just four touches in the opposition box and managed just one attempt, which did hit the target, in Monday's game.

Klopp would have loved to have the star duo at his disposal on Thursday, however, as Liverpool were frustrated by 10-man Arsenal in the first leg of their EFL Cup semi-final at Anfield.

Granit Xhaka's dismissal midway through the first half resulted in Mikel Arteta switching to an incredibly compact 5-3-1 system, which Liverpool were unable to break down.

The Reds had 78.1 per cent of the ball and 17 attempts to Arsenal's three, though only one of them – a stoppage-time effort from Curtis Jones – troubled Aaron Ramsdale.

Arsenal's goalkeeper had gifted Takumi Minamino a golden opportunity in the 90th minute, but the Japan international, who had a game-leading six attempts, failed to keep his shot down with the goal gaping. The chance was Liverpool's best of the game, according to Opta, with an expected goals (xG) value of 0.384.

Asked in a post-match news conference if Liverpool could have been better prepared for the absences of key players, Klopp replied: "Any team would miss Salah, Mane and Keita.

"Could we be prepared for it? I don't think so.

"We've known that already for years. This team was what we had tonight, it can play and score, definitely."

The Anfield leg of the semi-final had originally been set to be the second fixture, but a COVID-19 outbreak at Liverpool saw last week's game at Emirates Stadium postponed.

Klopp will now take his side down to north London next week knowing it is winner takes all for a place in the final against Chelsea.

"We weren't creative enough. We didn't do some things well enough but in the end it's 0-0, half-time [in the tie]," he said.

"We don't think this tie is over for us. We will give it a proper try next Thursday."

Should they progress to a Wembley showdown with Chelsea, Liverpool – who face Brentford in the Premier League on Sunday – will be bidding to win the EFL Cup for a record ninth time.

The Africa Cup of Nations group stage continues at pace on Friday, with four matches scheduled to take place.

Senegal, runners-up in 2019, face Guinea in Group B, with both teams having won their opening fixtures. Malawi and Zimbabwe take each other on in the other match in that group.

Meanwhile, Gabon are hoping to have Pierre-Emerick Aubameyang back for their clash with Ghana in Group C, while Morocco, winners against the Black Stars on matchday one, take on Comoros.

Senegal v Guinea (13:00 GMT)

Senegal and Guinea are meeting for the third time at the Africa Cup of Nations, with the former winning their first two encounters: 2-1 in the 1994 group stages and 3-2 in the 2006 quarter-finals.

In both matches, Guinea opened the scoring before eventually finishing as the losing side, and it is Senegal – led, of course, by Sadio Mane – who will be favourites on Friday, the Liverpool forward's 97th-minute penalty sealing an opening win against Zimbabwe.

Mane's fellow Red Naby Keita is Guinea's star man. He attempted more passes in the opposition half (26) than any of his team-mates in the 1-0 defeat of Malawi last time out and it was his precise ball that led to the only goal of the game.

Keita might have his work cut out against a Senegal midfield that will likely include Paris Saint-Germain's all-action Idrissa Gueye, the towering presence of Crystal Palace's Cheikhou Kouyate and Bayern Munich's versatile full-back Bouna Sarr, who had five attempts and played two key passes in the win over Zimbabwe.

One to watch: Sadio Mane

After his last-gasp winner on Monday, Mane has been directly involved in five of Senegal's past six AFCON goals, scoring four and providing one assist. Since his debut in the competition in January 2015, the former Southampton star has been directly involved in more goals than any other Senegal player.

Malawi v Zimbabwe (16:00)

After narrow defeats in their opening matches, Group B's other teams will be looking to bounce back knowing they could draw level with one of the pool's big sides with three points.

That being said, neither team exactly have a strong history in the competition. This will be the first encounter between the nations at an AFCON finals, with Malawi winning just one of their seven matches at the tournament (D1 L5).

Zimbabwe, meanwhile, are winless in their past seven AFCON matches (D2 L5), last claiming a victory in the competition in 2006, against Ghana (2-1).

It could be a case of an easily stoppable force meeting a highly movable object, however, with Malawi having failed to score in four of their past seven AFCON games, while Zimbabwe have never kept a clean sheet in 13 such matches, conceding 28 goals. No team has ever played more games in the competition without once keeping the ball out of their own net.

One to watch: Tino Kadewere (Zimbabwe)

Lyon forward Kadewere had to settle for a place on the bench in the first game, though he came on for the second half and had two attempts, which was bettered by only Knowledge Musona for Zimbabwe. In a squad shy of top-level European experience, Kadewere is undoubtedly the standout talent.

Morocco v Comoros (16:00)

After Senegal, Morocco are the second-best-ranked team at AFCON, currently placed 28th in the FIFA's world standings.

The Atlas Lions defeated Ghana in their opening Group C match and head into Friday's meeting with minnows Comoros as huge favourites, with Morocco looking to win their opening two matches at an AFCON in consecutive editions of the tournament, having only won both such games in one of their previous 16 appearances in the competition.

Comoros, who went down 1-0 to Gabon on Monday, will hope to avoid becoming the sixth AFCON debutants this century to lose their opening two matches, after Benin (2004), Botswana (2012), Burundi (2019), Niger (2012) and Zimbabwe (2004).

One to watch: Sofiane Boufal

Former Southampton midfielder Boufal scored an 83rd-minute winner against Ghana. No Moroccan player has netted in successive AFCON matches since Houssine Kharja in 2012.

Gabon v Ghana (19:00)

Friday's headline clash sees Gabon take on Ghana, and Aubameyang could well be back after he trained with his side following a negative coronavirus result.

Aubameyang, who has not played for Arsenal since early December and was recently stripped of the club captaincy due to a disciplinary breach, tested positive for COVID-19 upon his arrival for the AFCON, along with Mario Lemina.

Gabon will, however, be without coach Patrice Neveu, who is isolating. They are looking to win successive AFCON games for the first time since a run of three victories in 2012.

Four-time champions Ghana, meanwhile, have won just one of their past five group games (D2 L2), losing more in this run than in their previous 12 such matches combined (W9 D2 L1).

One to watch: Pierre-Emerick Aubameyang

There is no doubting Aubameyang's quality, even if the 32-year-old has been ostracised at Arsenal recently. Having been out of action for so long, it may take the former Borussia Dortmund star time to get up to speed, though he has the ability to be the difference-maker. 

Senegal got their Africa Cup of Nations campaign started with a 1-0 win over Zimbabwe, as Sadio Mane scored the decisive goal with a matter of seconds remaining.

Aliou Cisse's side were without as many as six "indisputable starting players" due to a COVID-19 outbreak, which impacted the likes of Edouard Mendy and Kalidou Koulibaly.

But even allowing for their absences, the Teranga Lions failed to meet expectations for much of the match.

Keita Balde summed up their performance early on, wasting one of few clear opportunities when shooting over from close range, and Mane spurned another good chance.

The game was largely played at a pedestrian pace in the heat of Bafoussam, but Boulaye Dia sprung into action 14 minutes from time and looked certain to square to Mane for a tap-in, only for Petros Mhari to brilliantly hold on to the squared pass.

Zimbabwe looked set to hang on, but in the final 10 seconds of stoppage time, Kelvin Madzongwe charged down a shot and accidentally handled the ball, allowing Mane to smash home the resulting penalty.

The Africa Cup of Nations is in full swing following its big kick-off on Sunday, and Monday sees the action taken up a notch.

There will be twice as many games as Group B and Group C get under way, providing first opportunities to see two of the pre-tournament favourites: Morocco and Senegal.

But the shroud of COVID-19 lingers over practically every AFCON match at the moment, and it will be especially difficult to ignore its impact on games on Monday, with the likes of Senegal, Guinea, Malawi and Gabon all missing key players.

Senegal v Zimbabwe (13:00 GMT)

Senegal's second so-called 'golden generation' is running out of time.

They arrived in Cameroon with a stacked squad, but many of their key players are approaching 30 or are already there.

To make matters worse, coach Aliou Cisse is without a host of big players against Zimbabwe, a game he will be keen to just get out of the way.

"I was looking at the composition of our team," Cisse said. "Compared to our last match against Congo, I can already tell you we have six indisputable starting players who are not on the squad list: Edouard Mendy, Krepin Diatta, Ismaila Sarr, Nampalys Mendy, Kalidou Koulibaly and Saliou Ciss.

"Having six absent starting players, it's true that it's worrying."

One to watch: Sadio Mane (Senegal)

Senegal have one of the best squads – if not the very best – in the tournament, but they are going to rely on Mane to a certain degree, particularly given their COVID-19 absences. Thankfully he is exceptional both when it comes to sniffing out chances and creating them, with his 0.67 non-penalty expected goal involvements every 90 minutes being the fourth-best in the Premier League (min. 900 minutes played) this term.

Guinea v Malawi (16:00 GMT)

Both Guinea and Malawi have been among the sides struck by coronavirus ahead of this tournament, but the former should still fancy their chances on Monday against a team considered Group B's rank outsiders.

Anything but three points will be a major disappointment for Guinea on matchday one, and key player Naby Keita is not among those to be afflicted with COVID-19.

As such, coach Kaba Diawara is feeling confident.

"We have the ambition to go as far as possible in this competition, which is why I accepted this mission," Diawara told Africa Top Sports ahead of the tournament.

"It's clear that it is the results that will speak. We try to put things in place, sometimes it works, sometimes it doesn't."

One to watch: Mohamed Bayo (Guinea)

While Naby Keita may be the team's most-recognisable star, expectations on Bayo are significant given he heads into the tournament with nine Ligue 1 goals to his name with Clermont this season, 45 per cent of their total output, and only one was a penalty. Only Jonathan David (12) and Wissam Ben Yedder and Ludovic Ajorque (both 10) have scored more in the French top flight so far.

Morocco v Ghana (16:00 GMT)

After Senegal (60.9 per cent), Morocco are the likeliest to finish top of a group at the AFCON (52.6 per cent), according to Stats Perform analysis. This speaks to the quality in the side assembled by Vahid Halilhodzic.

Even without Chelsea star Hakim Ziyech, who has been exiled, Morocco boast some fine players and will be expected to go deep into the competition – not that coach Halilhodzic is taking anything for granted.

"We have to prepare well to face the three teams in the group: Ghana, Gabon, and the Comoros," the Bosnian told reporters.

"Although Morocco are favourites to reach the second round, we have to prepare well and play with a lot of ambition and determination to go as far as possible."

One to watch: Yassine Bounou (Morocco)

This is likely to be Morocco's biggest challenge in the group stage, so they will want to be solid at the back. Bounou should help them in that respect – the Sevilla goalkeeper's 25 clean sheets in all competitions in 2021 was a total bettered only by Ederson (26) and Edouard Mendy (27) across the top five leagues in Europe.

Comoros v Gabon (19:00 GMT)

Comoros' Group C opener will be a momentous game as they play in a major international tournament for the first time.

Making a splash will be tough, but coach Amir Abdou is adamant they are more than worthy of their place in Cameroon.

He told Africa Foot United: "We haven't qualified by chance. We therefore don't think that we will let the opportunity to go as far as possible slip away.

"We will fight with our weapons with our various opponents, as tough as they are."

One to watch: Denis Bouanga (Gabon)

Gabon are likely to be without two of their most experienced players in Pierre-Emerick Aubameyang and Mario Lemina due to coronavirus, meaning others will need to step up. Bouanga will probably be among those expected to take on greater responsibility. The gifted Saint-Etienne left-winger is a good dribbler and takes a lot of shots, his 3.4 attempts per 90 minutes being the fifth-most in Ligue 1 this season (min. 900 minutes played).

Harvey Elliott has been inspired by working alongside Mohamed Salah and Sadio Mane, but now he sees the duo as part of the competition for first-team opportunities at Liverpool.

Elliott was handed his full Premier League debut by Jurgen Klopp in Saturday's 2-0 win over Burnley, becoming the 10th youngest player start a top-flight game for Liverpool and the youngest since Ben Woodburn in April 2017.

The 18-year-old previously appeared for Fulham aged just 16 years and 30 days, making him the youngest player to appear in Premier League history.

However, after a positive loan spell with Blackburn in the Championship last term, Elliott is back at Anfield and proving he can fit right in to Klopp's team.

"The first few training sessions after I first arrived at Liverpool was like, woah, I am actually training with these guys," Elliott responded to The Athletic and BT Sport about Salah and Mane.

"Going from watching them live on TV to seeing them in person and training alongside them, you really realise what a presence they bring. They are world-class players but we're all here to fight for a place in the team.

"We're all competing for the same thing. Now I look upon them as my competition. I learn a lot from them.

"They are great inspirations to kids around the world — and to me too — with what they have been through and what they've achieved. I want to achieve big things like they have."

Used in a midfield role against Burnley, Elliott produced three key passes – the third-most of any Liverpool player – and completed 90 per cent of his attempted passes in the opposing team's half. Only Trent Alexander-Arnold, who set up Mane to make it 2-0, attempted more (42).

Teenager Elliott knows he must keep on improving to challenge Salah and Mane, who became the fifth player to hit 50 home goals for Liverpool with his second-half strike at Anfield.

"Even to this day I'm not as quick as I’d like to be," he admitted.

"You can never be happy with what you are, you always need to push yourself. I still need to improve my speed, especially when you look at players like Mohamed Salah and Sadio Mane."

Asked about being versatile, he explained: "It’s what players need in their game, being able to adapt to different positions.

"It gives me more of a chance of getting into the team. It’s been a challenge to adapt.

"It's a case of getting your head around knowing where you need to be, how and when you need to press, knowing who you are needing to deal with on their team. I'm enjoying playing somewhere else."

Jurgen Klopp hailed Liverpool's reaction to the concession of an early goal after they came from behind to beat Manchester United 4-2 at Old Trafford.

The Reds looked set for another disappointing visit to the home of their bitter rivals when Bruno Fernandes opened the scoring after just 10 minutes on Thursday evening.

But goals from Diogo Jota and Mohamed Salah either side of a Roberto Firmino brace rendered a further Marcus Rashford effort irrelevant and handed Liverpool their first Old Trafford win since 2014.

And it was the mental strength shown in the aftermath of the early setback that most pleased Klopp.

He told Sky Sports: "We reacted really well on their goal, it was unlucky in that moment but it was a bit like we started the game to be honest. 

"The defending in that moment, letting Bruno, half right side, coming inside - there was nobody. 

"He could have used his left, could've used the outside of his right foot and it was unlucky in the centre but the defending in that moment wasn't good. 

"They overloaded the wings obviously and we didn't adapt well to that in the first 15 minutes or so. 

"Then we got control and from that moment on we could play what we want to play. That was absolutely okay and second half even better.

"Great fight, good game, intense, how a derby should be, and since I'm at Liverpool the first win at Old Trafford. 

"Good timing, I would say! We needed it, we fought hard for it, we deserved it and so all good."

Chelsea's defeat to Arsenal on Wednesday opened the door for Liverpool to claim a place in the Champions League spots with four wins from their last four games of this season.

But, while it is one down as far as that aim is concerned, Klopp is expecting the remaining three Premier League fixtures to throw up plenty of challenges.

"It was necessary. Without this result we don't have to talk too much about it," he added.

"We are still in the race, that's all that we could have done tonight, we did that and now we have a very intense period playing the next three games in a week.

"In three days West Brom, Burnley with supporters, and then Crystal Palace at home, which we are looking forward to for different reasons because our supporters are there then hopefully.

"We have to recover quickly and to go again."

If there was one small blot on a good evening for Liverpool, it was an apparent spat between Klopp and substitute Sadio Mane at full-time.

Asked about the Senegalese's refusal to acknowledge his manager when leaving the pitch, he said: "There's no problem. 

"Yesterday I made a late decision in training to decide Diogo. I explain things usually but there was no time for that.

"That's all. It's all fine."

Liverpool took charge of their Champions League last-16 tie with RB Leipzig as they claimed a 2-0 win in the first leg in Budapest.

Julian Nagelsmann's side, who pipped Manchester United to a place in the knockouts, looked far from comfortable in the unfamiliar surroundings of the Puskas Arena, where Tuesday's game was held to due to coronavirus travel restrictions.

Mohamed Salah's 24th goal of the season put Liverpool ahead after a mistake by Kevin Kampl, and Sadio Mane doubled the advantage when Nordi Mukiele gifted him an opportunity.

The Reds are now unbeaten in six away games against Bundesliga opposition stretching back to 2002, and Jurgen Klopp's men will be firm favourites to progress to the quarter-finals.

Liverpool nearly fell behind after just five minutes, Dani Olmo's diving header hitting the inside of the post from Angelino's cross.

The away side looked the most threatening as they began to take control, and Peter Gulacsi was alert to block a Salah effort from close range before Roberto Firmino fired a shot into the side-netting.

Mane then headed over from six yards from a Firmino cross, and the Senegalese thought he had set up his strike partner to nod in the opener after errors from Dayot Upamecano, but the ball had gone out of play.

Christopher Nkunku had barely been involved in the first half but he could have given Leipzig the lead early in the second, Alisson saving well after the striker ran onto Olmo's throughball.

It was Salah who broke the deadlock 53 minutes in, drilling past Gulacsi after a dreadful backpass from Kampl, and it soon got worse for Leipzig.

Mukiele made a complete mess of a simple clearance forward by Curtis Jones, and Mane had time to stride into the box and slot home.

Angelino had a chance to pull a goal back but sliced his attempt badly, summing up a poor game for last season's semi-finalists.

What does it mean? Fragile Liverpool give season huge boost

Injuries and recent form - they had won three of their previous 12 games in all competitions - will have had Liverpool fans feeling a little anxious before meeting the side second in the Bundesliga.

However, a display of supreme authority, helped by an erratic approach from Leipzig, put Klopp's men in total charge of this tie and could well have provided a timely boost in confidence.

Leipzig will hope for better in the second leg, but their previous visit to England ended in a 5-0 defeat to Manchester United.

Salah at menacing best

Salah should perhaps have scored sooner but he made no mistake with his clearest chance of the game.

He spent the rest of the game harassing a deeply unsettled Leipzig defence in a hugely impressive, committed performance.

Nagelsmann's men in a muddle

Leipzig were on a six-game unbeaten run at home in this competition and it was unfortunate for them that this game had to be relocated to a neutral venue.

Still, that does not explain the horribly haphazard nature of their performance. Two defensive errors led directly to the goals, Mukiele could have been sent off before his mistake, while Bayern Munich-bound Upamecano misplaced 20 passes from centre-back.

What's next?

With the return leg not until March 10, Liverpool's more pressing concern is a derby with Everton on Saturday. Leipzig head to Hertha Berlin in the Bundesliga a day later.

Liverpool have received a triple fitness boost for their clash with Manchester City as Sadio Mane, Alisson Becker and Fabinho return from injury to start.

Fabinho is back following a three-game absence necessitated by a muscle issue, while Mane returns after a similar problem forced him to miss the Reds' last two fixtures.

Alisson, meanwhile, is back in goal after illness kept him out of the midweek defeat to Brighton and Hove Albion at Anfield.

That trio's availability accounts for three of the hosts' four changes, with 20-year-old midfielder Curtis Jones replacing the experienced James Milner the other.

Manchester City, meanwhile, make two changes to the starting XI that beat Burnley in midweek, with Pep Guardiola opting against naming a recognised striker as Gabriel Jesus drops out for Phil Foden.

At the back, Aymeric Laporte makes way, with Oleksandr Zinchenko his replacement.

Manchester United boss Ole Gunnar Solskjaer left Bruno Fernandes out of his starting line-up for Sunday's FA Cup clash with Liverpool.

Fernandes, who has been United's shining light since arriving from Sporting CP almost 12 months ago, was only a substitute for the fourth-round game.

This season he has scored 15 goals and supplied nine assists in 28 games across all competitions from his advanced midfield role, but there have been questions asked about his form in recent weeks.

He has just one goal and no assists in four Premier League appearances since the turn of the year.

Into the United team went former Ajax midfielder Donny van de Beek as Solskjaer decided the game presented a chance to rotate his squad, making five changes to the side that won 2-1 at Fulham on Wednesday.

Solskjaer explained why Fernandes did not start, saying on BBC One: "It's rotation in the squad.

"Donny needs to be playing games as well and it's a big game for Donny to come into.

"He's done nothing wrong when he's been around the club so I'm looking forward to seeing him in there."

Premier League leaders United also brought in goalkeeper Dean Henderson, centre-back Victor Lindelof, midfielder Scott McTominay and forward Marcus Rashford, as David De Gea, Eric Bailly, Fred and Anthony Martial dropped out.

Liverpool also showed five changes as Jurgen Klopp looked for a response to Thursday's shock 1-0 home defeat to Burnley, which ended a 68-game unbeaten run at Anfield in the Premier League.

Teenage centre-back Rhys Williams came in for the absent Joel Matip, while James Milner and Curtis Jones were selected as Xherdan Shaqiri and Alex Oxlade-Chamberlain dropped to the bench.

Sadio Mane and Divock Origi were also substitutes as Klopp gave starts to Mohamed Salah and Roberto Firmino, with the Old Trafford clash coming a week on from these two sides battling out a dreary goalless draw at Anfield in the league.