Liverpool closed the gap on leaders Manchester City with victory over West Ham, while Chelsea tightened their grip on third place in Saturday's Premier League action.
The Blues saw off Burnley 4-0 at Turf Moor, a scoreline that was matched by Aston Villa in their statement victory against Southampton.
Newcastle United, Crystal Palace and Brentford also picked up wins, but it was a bad start to life under new management for Leeds in their early kick-off against Leicester City.
Following another eventful day of Premier League action, Stats Perform delves into the key Opta facts from each of the games.
Leeds United 0-1 Leicester City: New manager, same Leeds
Jesse Marsch's first game as Leeds boss ended in defeat to Leicester as United fell to a fifth successive league loss for the first time since April 2015, when they were in the Championship.
Leeds have failed to score in three straight league matches for the first time in a year, this despite registering 19 shots in their latest blank against Leicester.
United's expected goals (xG) return of 1.95 is their highest without scoring in a league game since June 2020, and the familiar failings were also on show at the other end.
Harvey Barnes' second-half winner means Leeds have gone 13 league games without a clean sheet, their longest-such run since 14 without a shutout ending in August 2016.
This was the fifth straight league game Barnes has scored against Leeds – four of those while playing for Leicester and one for West Brom, making them his favourite opponent.
Aston Villa 4-0 Southampton: Coutinho's home comforts
Villa are firmly back on track after registering back-to-back victories under Steven Gerrard for the first time since his opening two games in charge in November.
The Villans put four unanswered goals past Southampton at Villa Park for their biggest Premier League win since thrashing Liverpool 7-2 in October 2020.
Barcelona loanee Philippe Coutinho once again played a big part in the victory by scoring one and assisting another for Douglas Luiz.
Coutinho has now been directly involved in six goals in his first four home league games for Villa, scoring three of his own and setting up as many.
Ollie Watkins had earlier opened the scoring with his 21st Premier League strike since the start of the 2020-21 season, while Danny Ings added to his two assists with Villa's fourth goal.
Newcastle United 2-1 Brighton and Hove Albion: Fraser helps end Magpies' duck against Seagulls
For a while things looked incredibly bleak for Newcastle, even after their big-money takeover, but they now find themselves seven points above the relegation zone.
The Magpies held off Brighton to make it eight Premier League games without defeat – no team is on a better such run – with five of those matches ending in victory.
Ryan Fraser opened the scoring to make it two goals in five Premier League outings, matching his tally from his previous 70 appearances, before setting up Fabian Schar.
That was the earliest United have scored twice in a Premier League home game since January 2007 and, despite Lewis Dunk's header, Eddie Howe's side saw out the win.
It marks the first time Newcastle have defeated Brighton in the Premier League in their 10th such encounter, having previously failed to so much as score against them at home.
Norwich City 1-3 Brentford: Bees buzzing thanks to Toney treble
After a run of eight Premier League games without a win, Brentford bolstered their survival ambitions with a well-earned victory away at bottom side Norwich.
Ivan Toney was the hero for the Bees with three goals, two of those from the penalty spot, making Brentford the 40th different team to boast a hat-trick scorer.
The Brentford striker now has nine Premier League goals for the season, each of those coming via his right foot.
Teemu Pukki scored a consolation but it was another miserable day for Norwich, whose goal difference of -42 is the worst at this stage since Derby County in 2007-08 (-44).
Not that it will matter a great deal in the grand scheme of things, but Brentford are the first team Pukki has scored home and away against in a single Premier League season.
Wolves 0-2 Crystal Palace: Shaky Wanderers lose again
Wolves' European hopes suffered another blow as they fell to a third successive Premier League defeat, as many as they lost in their previous 13.
Bruno Lage's out-of-form side have now conceded six goals in their last four league games, after shipping just five in 12 before that.
Jean-Philippe Mateta came up with the breakthrough from close range for his fourth goal in eight Premier League starts, and Wilfried Zaha doubled Palace's lead from the penalty spot.
Ivory Coast international Zaha has now been directly involved in 83 goals in the competition, the joint-ninth best total for an African player, level with Nwankwo Kanu.
With this latest loss, it is the first time Wolves have lost three games in a row against Palace in their entire league history.
Burnley 0-4 Chelsea: Blues cruise at Turf Moor
It was business as usual for Chelsea as they won for a third Premier League game running without conceding in what proved to be a straightforward victory at lowly Burnley.
The Blues scored all four of their goals in the second half as they enjoyed their biggest away league win since October 2018 when also beating Burnley by the same scoreline.
This was the biggest margin of victory for an away side in a game that was goalless at half-time since Tottenham beat Aston Villa 4-0 in December 2012.
Reece James started the scoring and in the process became the first defender from Europe's top five leagues to both score and assist five goals this term in all competitions.
Kai Havertz also netted twice before Christian Pulisic added some gloss to the scoreline – his fourth goal at Turf Moor, matching a record for an away player set by Tottenham's Harry Kane.
Liverpool 1-0 West Ham: Reds roll on thanks to Mane
Sadio Mane's first-half goal made it seven wins in a row for Liverpool in the Premier League, their best such streak since a run of 18 when they claimed the title two years ago.
That close-range finish was Mane's 12th of the season in the league, nine of those coming at Anfield – no player has scored more home goals in the division this season.
Trent Alexander-Arnold played the ball into the box for Mane's goal for his 16th assist in all competitions this term, more than he has ever registered in a single campaign.
Liverpool were not at their best and that was particularly true of Mohamed Salah, who failed to score from six shots – only against Stoke in April 2018 (seven) has he fared worse.
Incredibly, Virgil van Dijk has never been on the losing side for Liverpool in 60 Premier League home games at Anfield, setting a new record in that regard.
Salah's contract 'up to him and the club', says Slot
Arne Slot has asserted Mohamed Salah’s future is “up to him and the club”.
The Liverpool star has yet to make a decision on whether to renew his contract, and as it stands, will be leaving Anfield at the end of the season.
Salah remains a key player for the Reds, and leads the club for Premier League goals (seven) and assists (five) this term.
He scored the winner in the 72nd minute to complete Liverpool’s comeback against Brighton in the Premier League on Saturday, as they moved to the top of the table.
And despite the question marks over Salah's future, Slot is not concerned.
"[His future] is not what I think about. The only thing I think about is he is so important for us. Scores important goals, works hard for the team," the Liverpool boss told TNT Sports.
"I’m hoping he can enjoy that feeling many, many, many more times. Especially if I’m here but also if I’m not here. I’m hoping he can do this many more times.
"He’s been incredible for Liverpool over the past eight years. He’s been incredible for us this season and I hope he can continue doing this for the rest of the season and maybe longer to come, but that’s up to him and the club to find the idea about the future."
Salah could be in for a historic night on Tuesday when Liverpool face Bayer Leverkusen, having scored in each of his last five Champions League appearances at Anfield.
The last player to score in six consecutive home games in the competition for an English club was Ruud van Nistelrooy for Manchester United in April 2003.
Salah sparked renewed talk over his future after posting on Instagram on Sunday, saying that the feeling of scoring at Anfield would remain unforgettable “no matter what happens.”
But Slot was keen to quash any deeper meaning in the post.
"I haven’t spoken to him about that. You interpreted it in a way that maybe other people don’t," he told the press.
"I don’t look at Instagram posts of my players, I only talk to them which you can’t, which is the advantage I have.
"Mo is in a very good place at the moment. As long as he has been at Liverpool, he has been in a very good place, but this season again as well. I am hoping he will make a post after tomorrow and on Saturday again. What he said with that, that is not important.
"For me what is important is how he plays and what he tells me when we have conversations. That is what matters and not how you guys interpret one of his posts."
Silva grateful Fulham's dominance was rewarded with late win
Marco Silva believes Fulham claimed a "deserved win" against Brentford, though admits they should have secured the three points much earlier in their 2-1 victory.
It looked like Vitaly Janelt's 24th-minute strike against the run of play was going to wrap up all three points for Brentford, but Harry Wilson proved the Cottagers' hero off the bench, scoring twice in stoppage time to snatch the three points.
Fulham had dominated from the first whistle and had 26 shots, 12 of which were on target, though they struggled to find a way past their opponents' staunch defence until the 92nd minute.
Wilson became just the sixth player to score an equalising and match-winning goal from the 90th minute onwards in the Premier League, while his second goal was Fulham's latest-ever Premier League winner at 96:46.
Silva was delighted with how his team pushed until the final seconds to ensure they came away with a win.
"It was definitely a deserved win. We started on the front foot and dominated all the game. In the first 20 minutes, we had two clear chances to score," Silva told BBC Sport.
"After they scored, we didn't lose the confidence and the trust in ourselves, we kept pushing them back, and we created enough to not be losing at half-time.
"I told the players this is football, it can happen, but we have to keep pushing, working hard and playing our way.
"It was late, it should've been much before, but that's football."
Brentford, meanwhile, have now dropped a league-high 14 points from winning positions in the Premier League as they suffered a fifth consecutive away defeat in the competition.
In fact, they are the first side in the competition's history to score the first goal in four consecutive away games and lose all four.
They had defended resolutely until their late lapse in concentration, and even had a chance to win it, only for Bernd Leno's impressive save to keep out Fabio Carvalho in the 95th minute.
Thomas Frank, though, admitted he was not yet ready to take the positives from the performance after the disappointment of their late defeat.
"It was tough. It is emotionally very tough right now," Frank told Sky Sports.
"When you are leading in the 92nd minute, and you lose, it is tough. I don't think we hit our highest level. I think on the day Fulham were better.
"There was a lot of good defending and effort, and I thought that would have given us the win. We could have won it with the chance for Fabio Carvalho and then we lost.
"When we look at the game back, and we are more cool-headed, we will probably be very happy with the defensive standard. I thought there were unbelievable blocks, and recovery runs and all that we did well. On the ball, we didn't do enough."
Returning fan favourite Alonso calls Liverpool 'one of Europe's best'
Bayer Leverkusen coach Xabi Alonso hailed his former club Liverpool as "one of Europe's best" as he prepares for his Anfield return.
Alonso, who spent five successful years at Anfield and helped Liverpool win the Champions League in 2005, returns to his former stomping ground when Leverkusen take on the Reds on Tuesday.
Arne Slot has won 12 of his first 14 matches in charge of Liverpool, including all three in the Champions League so far.
Leverkusen have only won one of their 11 away major European matches in England (D3 L7), and have lost their last two visits to Anfield, and Alonso is under no illusion as to the scale of the task that awaits the reigning Bundesliga champions.
"For us, it is a big challenge," he said.
"Liverpool at the moment are one of the best, if not the best, in Europe, they are showing that in the Premier League and Champions League, a good squad, great coach. We're looking forward to it. Let's see what happens.
"You can play 70 minutes great but in 20 minutes it [the game] is gone, so it is mentally and emotionally we need to be ready.
"In all areas, they are really strong, so the process works really well. [Slot] has done a fantastic job in three months."
Alonso played 210 times across all competitions for Liverpool between 2004 and 2009, scoring 18 goals and providing 20 assists.
After winning the Champions League with the Reds in 2005, he helped them reach the final in 2007, though they lost to Milan on that occasion.
However, the Spaniard does not think he will have too much time for a trip down memory lane.
"Unfortunately, there is no time for tourism – maybe a little run or walk," he said.
"I know the city very well, I love it, but tomorrow I will focus on the game and only the game.
"It feels great to be back here after a few years. It's always special. You notice the development of the club; the new stand looks amazing.
"It is a big game against Liverpool, it cannot get much better than that."
The omens are not great for Leverkusen, though.
Liverpool have lost one of their last 21 European meetings with German opponents (W14 D6), albeit that one defeat came against Leverkusen in 2002.
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