The decision to ban Russian and Belarusian players from Wimbledon is "unfair" and sets a "damaging precedent for the game", the ATP has warned.

An announcement on the grand slam's official website on Wednesday stated that Russian and Belarusian competitors would be barred from the championships, as well as from any other events organised by the Lawn Tennis Association (LTA) this year.

"In the circumstances of such unjustified and unprecedented military aggression, it would be unacceptable for the Russian regime to derive any benefits from the involvement of Russian or Belarusian players with The Championships. It is therefore our intention, with deep regret, to decline entries from Russian and Belarusian players to The Championships 2022," the statement read.

ATP world number two Daniil Medvedev and WTA world number four Aryna Sabalenka headline the list of players who will miss out on the year's third grand slam as a result of the announcement.

The ATP has now hit out at the ban, labelling it "unfair" and discriminatory, while continuing to pledge solidarity with the people of Ukraine.

"We strongly condemn Russia's reprehensible invasion of Ukraine and stand in solidarity with the millions of innocent people affected by the ongoing war," began a press release from the ATP.

"Our sport is proud to operate on the fundamental principles of merit and fairness, where players compete as individuals to earn their place in tournaments based on the ATP Rankings. 

"We believe that today's unilateral decision by Wimbledon and the LTA to exclude players from Russia and Belarus from this year's British grass-court swing is unfair and has the potential to set a damaging precedent for the game. 

"Discrimination based on nationality also constitutes a violation of our agreement with Wimbledon that states that player entry is based solely on ATP Rankings. Any course of action in response to this decision will now be assessed in consultation with our Board and Member councils.

"It is important to stress that players from Russia and Belarus will continue to be allowed to compete at ATP events under a neutral flag, a position that has until now been shared across professional tennis. 

"In parallel, we will continue our joint humanitarian support for Ukraine under Tennis Plays for Peace."

The unilateral announcement from Wimbledon's organisers comes after Russian and Belarusian players were originally allowed to play under neutral flags amidst Russia's invasion of Ukraine, courtesy of a joint ruling from the four grand slams and the ATP and WTA Tours.

Elina Svitolina has called for Russian and Belarusian players to be banned from all international tennis events unless they denounce the invasion in Ukraine.

The All England Club on Wednesday announced that players from Russia and Belarus will not be allowed to compete at Wimbledon due to the conflict in Ukraine.

Daniil Medvedev, Aryna Sabalenka, Victoria Azarenka and Andrey Rublev are among the household names that will not be allowed to compete in the grass-court grand slam, "unless circumstances change materially between now and June".

Russian and Belarusian players will also be prevented from entering all other events organised by the Lawn Tennis Association.

Two-time major semi-finalist and former world number three Svitolina believes a global ban should be imposed on players from Russia and Belarus if they do not speak out.

The Ukrainian former world number three posted on Twitter and Instagram: "Dear Tennis Community.

"Ginetta Sagan once said: 'Silence in the face of injustice is complicity with the oppressor.' This could not be any more true right now.

"On 24th February 2022, Russia, with the support of Belarus, attacked Ukraine. Now there is a war in our country, in our home. All Ukrainians are forced to leave their homes and fight for their lives. For over 50 days now, the Russian forces have been bombing our cities and killing civilians, as well as using the territory of Belarus to bomb Ukraine from the west and the north.

"Millions of people have been left homeless, millions of children now know what explosions, fear and death look like. It is all happening right now in the centre of Europe.

"As athletes we live a life in the public eye and therefore have an enormous responsibility. Some of our posts and opinions on social media reach an audience larger than those of regional television stations. In times of crisis, silence means agreeing with what is happening.

"We noticed that some Russian and Belarusian players at some point vaguely mentioned the war, but never clearly stating that Russia and Belarus started it on the territory of Ukraine. The very silence of those who choose to remain that way right now is unbearable as it leads to the continuation of murder in our homeland.

"We demand that the WTA, ATP and ITF make sure the players who represent Russia and Belarus answer the following questions:

"1. Do you support Russia's and Belarus invasion in Ukraine's territory and as a result of that the war started by those countries?

"2. Do you support Russia's and Belarus military activities in Ukraine?

"3. Do you support [Russian president Vladimir] Putin's and [Belarus president Alexander] Lukashenko's regime?

"If applicable, we demand to exclude and ban Russian and Belarusian athletes from competing in any international event, as Wimbledon already [has] done. There come a time when silence is betrayal, and that time is now."

Daniil Medvedev headlines the list of Russian and Belarusian players who will be banned from competing at Wimbledon this year.

In the wake of Russia's invasion of Ukraine, which was facilitated by Belarus, the four grand slams and the ATP and WTA Tours initially confirmed Russian and Belarusian players would be able to continue playing, albeit under neutral flags.

However, the All England Club has now decided athletes from the two nations will be unable to feature at the season's third grand slam.

That means reigning US Open champion Medvedev, ranked second in the world by the ATP behind Novak Djokovic, will not be involved.

With Medvedev a doubt for the French Open having undergone hernia surgery, he could miss two of this year's majors. He has never had much success at Wimbledon, with his best run ending in the fourth round in 2021.

WTA world number four Aryna Sabalenka, who hails from Belarus, is another big name to miss out, along with Russian ATP world number eight Andrey Rublev, who has won two titles so far in 2022.

Russian women's number one Anastasia Pavlyuchenkova, compatriot and 2018 Wimbledon quarter-finalist Daria Kasatkina and Belarusian two-time All England Club semi-finalist Victoria Azarenka will all also be absent.

"We share in the universal condemnation of Russia's illegal actions and have carefully considered the situation in the context of our duties to the players, to our community and to the broader UK public as a British sporting institution," a statement on the official Wimbledon website read.

"We have also taken into account guidance set out by the UK Government specifically in relation to sporting bodies and events.

"In the circumstances of such unjustified and unprecedented military aggression, it would be unacceptable for the Russian regime to derive any benefits from the involvement of Russian or Belarusian players with The Championships. It is therefore our intention, with deep regret, to decline entries from Russian and Belarusian players to The Championships 2022."

Chairman of the All England Club, Ian Hewitt, said: "We recognise that this is hard on the individuals affected, and it is with sadness that they will suffer for the actions of the leaders of the Russian regime.

"We have very carefully considered the alternative measures that might be taken within the UK Government guidance but, given the high profile environment of The Championships, the importance of not allowing sport to be used to promote the Russian regime and our broader concerns for public and player (including family) safety, we do not believe it is viable to proceed on any other basis at The Championships."

Wimbledon's statement confirmed that the ban would be "reconsidered" should circumstances change by June.

The move comes a month after UK sports minister Nigel Huddleston warned Medvedev and other Russian athletes they might be banned from Wimbledon unless they denounced president Vladimir Putin.

Medvedev and Rublev both called for peace in the immediate aftermath of Russia's attack on Ukraine.

Dominic Thiem suffered defeat in his first ATP Tour match since June, losing at the Serbia Open to John Millman.

Thiem has been out of action since suffering a right wrist injury and the former world number three was able to claim the second set in his comeback match.

But he could not avoid a 6-3 3-6 6-4 defeat in a contest that lasted two hours and 35 minutes.

Speaking afterwards, Millman said: "It is great to be back here. I was looking forward to coming back and [playing]. All credit to Domi.

"I can't claim it was one of my biggest wins because he is just coming back from injury and I know how hard that is, coming back from three surgeries myself.

"I know it has been tough for Domi but the game is better having him back. Especially on this surface. I have got to take this win because when he gets better and fitter, it is going to be tough."

Next up for the Australian is Miomir Kecmanovic.

NextGen star Jiri Lehecka booked a meeting with second seed Andrey Rublev by beating Henri Laaksonen, while Filip Krajinovic overcame David Goffin.

At the Barcelona Open, fourth seed Cameron Norrie had to come back from a set down to see off Egor Gerasimov, though his 12th seeded fellow Briton Dan Evans lost to Lorenzo Musetti.

There were routine wins for second seed Casper Ruud, sixth seed Diego Schwartzman and 11th seed Lorenzo Sonego.

Cristian Garin was on the end of a shock thrashing by Denmark's Holger Rune in the first round of the Serbia Open on Monday.

The Chilean fifth seed, who was the highest-ranked player in action, is regarded as one of the ATP Tour's best on clay but hardly got a look-in as 18-year-old Rune emerged with an impressive 6-3 6-1 win.

Rune has risen to a career-high 72 in the ATP rankings and showed every sign that he will continue to climb over the season as he produced an aggressive performance that saw him take six of 17 break points.

Playing in only his fifth ATP Tour match on clay, Rune needed just an hour and 25 minutes to see off Garin – the winner of five tour-level titles on the surface – and set up a second-round clash with either Dusan Lajovic or Taro Daniel.

Sixth and seventh seeds Fabio Fognini and Miomir Kecmanovic avoided similar shocks, though their respective wins were wildly different.

Kecmanovic crushed veteran Richard Gasquet 6-0 6-3, while Fognini was forced to overturn a one-set deficit in his defeat of fellow Italian Marco Cecchinato 6-7 (5-7) 6-2 6-2.

No seeds were in action at the Barcelona Open, but Italian prospect Lorenzo Musetti enjoyed a hard-fought 7-5 7-5 defeat of Argentina's Sebastian Baez to seal his spot in the second round.

The 20-year-old is now 5-2 for the clay season and will go up against Dan Evans next. Joining Musetti in progressing is another promising youngster in Brandon Nakashima, who beat Nicolas Alvarez Varona 7-6 (8-6) 6-3 to tee up a clash with number two seed Casper Ruud.

Mackenzie McDonald, Elias Ymer, Kwon Soon-woo and Federico Coria were among the other victors, while retiring 2004 champion Tommy Robredo bowed out with a 6-1 6-1 loss to Bernabe Zapata Miralles.

Stefanos Tsitsipas defended his Monte Carlo Masters crown and lifted his eighth ATP Tour title by defeating Alejandro Davidovich Fokina in straight sets on Sunday.

Greek Tsitsipas, who defeated Andrey Rublev to triumph in Monaco last year, eased past second seed Alexander Zverev in the semi-final and repeated the trick with a 6-3 7-6 (7-3) victory over Davidovich Fokina.

The Spaniard beat Novak Djokovic and reigning Indian Wells Masters champion Taylor Fritz en route to his maiden ATP Tour final, and started well on Court Rainier III with an early break.

However, Tsitsipas found his rhythm with his ferocious forehand to break back before winning four of the next five games to take the lead.

The world number five, appearing in his fourth Masters 1000 final, then failed to serve out for the match at 5-4 up in the second set, but recovered in the tie-break to secure his first trophy of the season.

In doing so, Tsitsipas becomes the sixth player to manage consecutive Monte Carlo titles in the Open Era, while half of his eight tour-level titles have come on clay.

"I am very proud of myself," Tsitsipas said in his on-court interview. "Things weren't going well at one point, but I managed to stay composed to finish the match off.

"I am really proud with the belief I put in my game. Sometimes you doubt yourself, but it is always important to keep your head high."

Davidovich Fokina was aiming to become the first unseeded champion in Monte Carlo since Thomas Muster in 1992, and Tsitsipas acknowledged the 22-year-old made him fight to reclaim the trophy.

"He fought in moments I didn't expect him to fight," Tsitsipas said. "He can hit incredible winners out of nowhere and play unpredictably.

"But I was able to minimise that. I knew he would be a dangerous opponent but that is a great win for me. I think we will see great results from him in the future."

Stefanos Tsitsipas remains on course for a second consecutive Monte Carlo Masters title after recording a straight-sets semi-final win over Alexander Zverev.

The third seed, who defeated Andrey Rublev to clinch the title in Monaco last year, produced a scintillating performance to beat the world number three 6-4 6-2 in Saturday's last-four encounter.

Tsitsipas will face world number 46 Alejandro Davidovich Fokina in Sunday's final, and the Greek said he will need to perform at an even higher level to defeat the 22-year-old, whose incredible run continued with a three-set win over Grigor Dimitrov in the final four.

"It was good," Tstispas told Amazon Prime Video of his semi-final win. "I don't know whether the long match [his three-set quarter-final win over Diego Schwartzman on Friday] gave me some rhythm, but I was able to play good tennis today. I'm happy with the level I was able to execute, and I came up with some good ideas on the court.

"I'm looking forward to the next one, I have a difficult opponent tomorrow, so I need to be ready and to take the best out of this one and move on.

"It's going to take a little bit more [to beat Davidovich Fokina], he's in a good rhythm. I've played him before, and he's a difficult opponent, I'm going to be as ready as possible, he's definitely improved and I'm going to have to produce the best tennis I can."

Davidovich Fokina, who has made headlines by eliminating Novak Djokovic and Indian Wells Masters champion Taylor Fritz during a thrilling run in the municipality, beat Dimitrov 6-4 6-7 (2-7) 6-3 earlier on Saturday, reaching his first ATP Tour final.

The unseeded Spaniard needed two hours and 43 minutes to wrap up his semi-final contest, and revealed that a bathroom break allowed him to reset his mind and clinch a hard-fought victory after he failed to serve out the second set at 5-4 up.

"I am so happy to be in the final, it's a dream come true to try to have the title," he said after the win.

"When I was a kid, I was dreaming about this day and it's come true, I'm so happy.

"In the second set I had my chances, I was so tight. But I went to the bathroom [after the second set] and I said to myself 'I want this'. Now I am in the final, I will enjoy, I have all the power with me."

Reigning Monte Carlo Masters champion Stefanos Tsitsipas will have to overcome Alexander Zverev if he is to have the chance to defend his title.

Zverev, who is ranked third in the world - two places higher than Tsitsipas - fought back to defeat Jannik Sinner 5-7 6-3 7-6 (7-5) in his quarter-final match, denying his opponent another top-five seed scalp following his prior win over Andrey Rublev.

"It means a lot, definitely, especially [with] how this year has been going so far for me," said Zverev after a gruelling three hours on court.

"I've lost long matches like that, so I’m happy I won this one."

Tsitsipas also orchestrated a superb turnaround against Diego Schwartzman, prevailing 6-2 6-7 (3-7) 6-4.

The Greek had looked set for a last-eight exit at four games down in the final set, only to stage a dramatic comeback to keep his hopes of a first title since last May's Lyon Open alive.

"There was a moment in the match where I felt what I was doing wasn't working," Tsitsipas said.

"He had a massive lead and momentum in what he was trying to do. I just tried to stay in the match as much as I could and that worked out very well.

"I wasn't expecting much at that point being a double break down, so I relaxed at that point."

Schwartzman meanwhile will rue his inability to put the tie to bed, having already reached two ATP finals this year.

Grigor Dimitrov and Alejandro Davidovich Fokina will face off in the other semi-final.

Bulgarian Dimitrov beat off Hubert Hurkacz in another final-set tie-break, winning 6-4 3-6 7-6 (7-2).

Fokina, who eliminated Novak Djokovic in the second round, turned over Indian Wells champion Taylor Fritz in another comeback result, triumphing 2-6 6-4 6-3.

Alexander Zverev and Stefanos Tsitsipas progressed to the quarter-finals of the Monte Carlo Masters with straight sets wins on Thursday, remaining on course for a final meeting.

Last year's runner-up Andrey Rublev, however, missed out on a last-eight spot after falling to a three-set defeat against Jannik Sinner.

World number three Zverev overcame Spain's Pablo Carreno Busta 6-2 7-5 to progress in Monaco, where he is seeking to win the sixth ATP 1000 title of his career.

"For the second clay-court match of the season, I can't complain too much," the 24-year-old second seed said on court after sealing the victory.

"Yes, I lost focus a little bit in the second set, but at the end of the day, he's somebody that can really play. I'm happy with a two-set win."

Tsitsipas (3) remains in contention for a second consecutive title in the principality after defeating Laslo Dere 7-5 7-6 (7-1) and will face off against 12th seed Diego Schwartzman for a semi-final spot after the Argentine defeated Lorenzo Musetti in a hard-fought three-set encounter.

There will be no repeat of 2021's final between Tsitsipas and Rublev, however, after the Russian fell to a thrilling 5-7 6-1 6-3 loss to ninth seed Sinner in the day's final contest.

The other seed to fall victim to a shock in the last 16 was world number seven Casper Ruud, losing 6-3 7-5 to Grigor Dimitrov, who will face Poland's Hubert Hurkacz in the last eight. 

Finally, Novak Djokovic's conqueror Alejandro Davidovich Fokina cruised past David Goffin 6-4 6-1 to set up a quarter-final tie with the United States' Taylor Fritz, who bested compatriot Sebastian Korda – with whom he played doubles with in Monte Carlo – in straight sets.

Lorenzo Musetti headlined a day of shocks at the Monte Carlo Masters as Felix Auger-Aliassime fell to a first-round defeat.

Auger-Aliassime already has one singles title to his name this year, having prevailed in Rotterdam, and also reached the final of the Open 13 in Marseille and helped Canada to victory in the ATP Cup at the start of 2022.

However, the sixth seed entered this contest with just one win from his last four matches and came unstuck once again at the hands of Musetti. 

Musetti, who won two sets in the fourth round of the French Open against Novak Djokovic last year, is very much at home on the clay in Monaco.

He demonstrated that in 6-2 7-6 (7-2) success, setting up a last-16 meeting with Diego Schwartzman.

“I live here and practice here,” Musetti said in his on-court interview. "It is nice to be here and play here in front of such a crowd. I am really happy.

"My backhand down the line was a key to many of my great shots. After a really good first set, he came back with such powerful serving, but I was calm and patient and that was the most beautiful thing about today."

Auger-Aliassime's exit came a day after top seed Djokovic was knocked out in the second round by Alejandro Davidovich Fokina, but there were no such problems for second seed Alexander Zverev as he saw off Federico Delbonis in straight sets.

Fifth seed Andrey Rublev came from a set down to defeat Alex de Minaur and fourth seed Casper Ruud, coming off his defeat in the final in Miami, edged qualifier Holger Rune in two tight sets.

The man who vanquished Ruud in Florida will go no further on the Cote d'Azur, however, Carlos Alcaraz losing in just over three hours to Sebastian Korda on his Monte Carlo debut.

Korda lost to Alcaraz in the final of last year's Next Gen ATP Finals, but avenged that defeat with a 7-6 (7-2) 6-7 (5-7) 6-3 victory.

World number 10 Cameron Norrie lost to Albert-Ramos Vinolas and his British compatriot Dan Evans fell to David Goffin, while 16th seed Lorenzo Sonego was beaten by the in-form Laslo Djere.

Elsewhere in the draw, there were wins for Jannik Sinner, Taylor Fritz, Hubert Hurkacz and Pablo Carreno Busta.

World number one Novak Djokovic explained that he could just not get up to the level of sharpness required in his shock defeat at the Monte Carlo Masters.

Djokovic slumped out in the second round on Tuesday when he lost 6-3 6-7 (5-7) 6-1 to world number 46 Alejandro Davidovich Fokina.

The Serbian's status as an unvaccinated player has limited his ability to compete on the ATP Tour this year and he has played in just one tournament so far, getting to the quarter-finals in Dubai. 

Yet his preparations for the French Open, which starts at the end of next month, hardly got off to a good start as he made 51 unforced errors in what was still, despite his rustiness, a surprise defeat.

"I didn't like the way I felt physically in the third. I just ran out of the gas completely," Djokovic told the media. 

"Just couldn't really stay in the rally with him. I mean, if you can't stay in the rally, not feeling your legs on the clay, it's mission impossible.

"I'm going to look with my team into reasons why that was the case and go back to the drawing board. Hopefully next week will be better in Belgrade."

Though Djokovic has won twice in Monte Carlo, it has not been a happy hunting ground for him in recent years. He has not advanced past the quarter-final stage since 2015.

He added: "It's going to take some time for me to really feel my best on the clay.

"That's historically always been the case. [I have] never played very well in the opening tournaments of the clay season.

"But it's okay. Obviously it is what it is. I have to accept the defeat and keep working."

While unhappy with his own performance, Djokovic had nothing but praise for his opponent. 

"I would like to congratulate Alejandro. He was the better player," Djokovic said. "He managed to find a better rhythm I think in the first two sets. I was hanging on the ropes the entire match. I was really chasing the result constantly.

"I always believed that I could come back and win the match, and I stayed there even though a lot of things were against me in terms of how I felt on the court. Game-wise, physically I was just far from my best.

"I expected this match to be [a] really tough match, [a] physical battle, and that's what it was. Unfortunately I'm on the shorter end of the stick, and my week ends here."

Djokovic's defeat also means a mouthwatering contest with teenager sensation Carlos Alcaraz, who he might have met in the quarter-finals, will not be taking place.

Novak Djokovic suffered a stunning defeat in his first ATP Tour match since February, the world number one losing in the second round of the Monte Carlo Masters to Alejandro Davidovich Fokina.

Djokovic's status as an unvaccinated player has limited his ability to compete on the tour this year. He missed the Australian Open in January after a saga surrounding his visa eventually resulted in his deportation on public health grounds, while laws around vaccination against COVID-19 in the United States prevented him from playing at Indian Wells and Miami.

Despite his inactivity, the Serbian - whose sole appearance on tour this year came during a run to the quarter-finals in Dubai - was expected to prevail on the clay against his Spanish opponent after receiving a bye in the first round.

But there were evident signs of rust in a mistake-riddled display against the world number 46, who remarkably emerged victorious to set up a meeting with either Dan Evans or David Goffin.

The tide looked to have turned in the second set tie-break, when an exquisite whipped forehand from Djokovic sent the match to a decider.

However, Djokovic, who committed 51 unforced errors, immediately surrendered the momentum by dropping serve in the first game of the third and he was broken twice more as Davidovich Fokina powered to a 6-3 6-7 (5-7) 6-1 victory in just under three hours.

"I knew that Nole hasn't had that confidence because he didn't play a lot," Davidovich Fokina said.

"This win is so special for me. I look at him every tournament. Here in Monte Carlo, full people [capacity], against the number one, I enjoy every moment."

Earlier, Evans saw off Benjamin Bonzi while Goffin, fresh off his triumph in Marrakech, came through against Jiri Lehecka to set up their second-round meeting.

Tenth seed Taylor Fritz defeated Monegasque wild card Lucas Catarina in three sets and 16th seed Lorenzo Sonego saw off Ilya Ivashka in straight sets. Laslo Djere, a semi-finalist in Marrakech, also progressed to the second round.

Carlos Alcaraz is hopeful of meeting Novak Djokovic in the Monte-Carlo Masters, but his first focus is on a second-round tie with Sebastian Korda. 

Alcaraz is one of the brightest prospects on the ATP Tour, with the 18-year-old Spaniard having won his first Masters title at the Miami Open and become the youngest men's champion of that tournament. 

That was Alcaraz's second title of 2022 and third overall. He is now up to 11th in the ATP world rankings. 

Seeded eighth, Alcaraz has been handed a bye to the second round but is in the same quarter of the draw as world number one Djokovic, who has triumphed twice in Monte Carlo. 

Alcaraz, though, is making sure not to get ahead of himself and think too much about a maiden meeting with Djokovic, with American Korda – who defeated Botic van de Zandschulp in his first-round match – first up. 

"I don't want to be in a rush, I just focus on the first [match]," Alcaraz told reporters ahead of what is a rematch of the Next Gen ATP Finals championship match which he won in straight sets. 

"Obviously, it would be a great match against Novak. 

"Playing against the number one player in the world [would be] amazing for me, but I hope to play well in the first [matches] and hope to meet him in the quarter-finals." 

Alcaraz seems set to have a future at the very top of the game but is insisting everything must be taken step by step. 

"Sometimes it is difficult, but I am trying to make it easy," he said. 

"Doing everything for the first time, I am trying my best, trying to manage the nerves of the first time well." 

Taylor Fritz, who won a Masters title at Indian Wells earlier this year, could also be standing in the way of Alcaraz and the quarter-finals, should the American defeat wildcard Lucas Catarina and Marin Cilic. 

Djokovic, on the other hand, faces Alejandro Davidovich Fokina in his first match. 

Stan Wawrinka's ATP Tour return at the Monte-Carlo Masters ended in defeat, while Jannik Sinner came through a tense encounter with Borna Coric. 

The former world number three made his comeback after more than a year out with a left foot injury that required two surgeries but fell to a 3-6 7-5 6-2 defeat to Alexander Bublik in the first round. 

Wawrinka, who entered the tournament as a wildcard having slipped to 236 in the world rankings, came from a break down to take the opening set but fatigue eventually set in and he was eliminated after two hours and seven minutes. 

"I think the body's getting much better," said Wawrinka, who lost in straight sets to Elias Ymer at a Challenger tournament in Marbella two weeks ago. 

"I'm still far away from where I want to be, but I think I'm [going in] the right direction. I think today was a positive match. It was a tough loss, of course, but I'm happy with the way I was playing today. 

"I was playing better, feeling better on the court physically. I spent a lot of mental energy to focus, to stay there as it was tough at the end. But I'm happy with what I have done."

Ninth seed Sinner was taken the distance by Coric before completing a 6-3 2-6 6-3 victory to advance to the second round. 

Sinner took a medical timeout in the second set while he dealt with some apparent abdominal pain, but he was able to battle back and take the win. 

Diego Schwartzman needed over three hours to come from behind and defeat Karen Khachanov 6-7 (5-7) 6-3 6-3, while his fellow Argentine Federico Delbonis set up a clash with second seed Alexander Zverev by besting Jaume Munar 6-4 3-6 6-4. 

Reigning champion Stefanos Tsitsipas faces a meeting with Fabio Fognini in the second round after the Italian overcame Arthur Rinderknech 7-5 4-6 6-3.  

There were also wins for Hubert Hurkacz, Pablo Carreno Busta, Marin Cilic, Alex de Minaur, Albert Ramos-Vinolas and Sebastian Korda. 

American Reilly Opelka defeated compatriot John Isner 6-3 7-6 (9-7) to win a history-making final of the US Men's Clay Court Championships in Houston.

In a clash between two of the tour's elite servers, and two of the tallest men to ever play professional tennis, break points were hard to come by, and even harder to convert, as Opelka saved all eight opportunities he faced, while Isner saved four out of five.

That one break decided the first set, as 6ft 10in Isner fought back from 40-0 down to force deuce, but the fourth break point of the game was converted by 6ft 11in rival Opelka.

The ATP said their respective heights made it the tallest tour final in the Open Era.

In a match that was always likely to be decided by whoever served best, Opelka had five aces to Isner's two in the first set, while Isner also had the only double fault.

Isner was much stronger in the second set, creating seven break-point opportunities, but he just could not win the important points as Opelka's serve repeatedly got him out of trouble.

Isner then had three opportunities at set point in the tie-break to force a decider, but it was Opelka's day, as he saved all three and converted his first chance at match point.

After dropping a set in his first-round match against Mitchell Krueger, Opelka was perfect the rest of the tournament, beating Gijs Brouwer and Nick Kyrgios in straight sets on his way to the final.