Rafael Nadal's loss to Frances Tiafoe opened up a host of possibilities including a first-time world number one and maiden grand slam winner as the top three's domination of men's singles continues to weaken.
World number three Nadal bowed out in the fourth round to 22nd seed Tiafoe 6-4 4-6 6-4 6-3 on Monday, while third seed Alcaraz triumphed over Marin Cilic 6-4 3-6 6-4 4-6 6-3 in a match that went to almost 2:30am local time.
Cilic was the last remaining male player with a grand slam title to his name, meaning this year's US Open will bring a new major champion.
There may also be a first-time world number one too, with Alcaraz guaranteed to claim the top rank if he wins the US Open title.
Fifth seed Casper Ruud will rise to world number one if he lifts the US Open crown at Flushing Meadows on September 11 too.
If both fall short of the final, Nadal will reclaim the top ranking from 2021 US Open champion Daniil Medvedev, who lost in the fourth round to Nick Kyrgios.
Alcaraz could also scale the rankings summit should he reach the final, assuming Ruud misses out.
Overall leader at the Vuelta a Espana, Remco Evenepoel, discussed the chess match between those vying for the general classification (GC) title as he holds the lead through 15 stages.
On Sunday for the 15th stage, Belgium's Evenepoel finished 10th, 11 seconds behind his top GC rival Slovenian Primoz Roglic, while Spain's Enric Mas also cut into the lead.
Evenepoel will carry the red jersey and a one-minute-34-second lead into the 16th stage on Tuesday, and when speaking to the media he dove into the strategy of a grand tour (GT).
"Roglic and Mas are both going very well," he said. "Roglic was the strongest of all the GC guys on Saturday, Mas was very strong [on Sunday].
"When Mas attacked I also knew I was still quite a bit ahead of him in the GC so I didn’t want to go above my own limits, because we were already above 2000m of altitude and what we saw is they attacked, took a gap but then me keeping up my own pace didn’t really allow them to ride away.
"I was a bit scared to go above my limits, so I kept pushing my own power, and I think on such a hard stage the time loss was quite limited.
"It’s now the third week, the guy with the best legs will probably be the best in the mountain stages, but the Vuelta is far from over."
With six stages remaining, Evenepoel has a chance to become the first Belgian winner of a GT since 1978, but he says he does not feel pressured to finish the job because he did not expect to be in this position.
"I know that I can be the first winner of a GT for Belgium in a long time, but we’ve still got six days to go so I don’t want to call myself that already," he said.
"For the head it’s best to just try to stay calm and look at the races day by day, see what everyday brings. As we saw last week, a crash happens before you even know it.
"We had two big passes, unfortunately Julian had to abandon the race, I was okay but there was still some damage to my hip and muscles, so that’s why we have to see day by day.
"Never panic, even if I lose a bit of time, because if I’d have known I was in this situation before the Vuelta, I would have signed up for it, so everything that happens now is extra.
"A stage win and a top 10, top five, would be my big dream. I think we’re on the road to that."
Shohei Ohtani continues to put forward his case for back-to-back American League (AL) MVP awards as the All-Star pitcher blasted two home runs in the Los Angeles Angels' 10-0 home win against the Detroit Tigers on Monday.
Ohtani, who was also named an All-Star as a batter, hit a double in the first inning, and then connected on a 382-foot, two-run homer with his next at-bat in the third frame.
He was robbed of another hit when his 100mph line drive was caught by the Tigers first-baseman, but there was nothing they could do about his massive 416-foot launch in the seventh inning for his second home run of the game.
Also getting in on the fun was three-time AL MVP Mike Trout, who had a single, a double and a home run as the Angels' two superstars combined to go six-for-nine at the plate with three home runs and two doubles.
Ohtani is now tied for sixth in the majors with 32 home runs this season, while Trout is tied for 10th with 30 home runs. Trout has played 16 games fewer than any other player with 30 homers, and Ohtani is also eighth in the majors for strikeouts as a pitcher (181 in 23 starts).
On the mound, Jose Suarez was spectacular for the Angels, pitching seven scoreless innings while only giving up three hits and one walk, striking out seven.
Judge homers for third consecutive day
Ohtani's biggest challenger for the AL MVP, and the heavy favourite, Aaron Judge hit a home run for the third day in a row to help his New York Yankees defeat the Minnesota Twins 5-2 at home.
Judge's hot streak has now seen him hit five home runs from his past seven games, taking his league-leading tally to 54 – 18 more than any other player. He is now seven home runs away from the Yankees' all-time record of 61 in a season, set 61 years ago, in 1961, by Roger Maris.
His big hit on Monday came at the perfect time, with his two-run homer in the sixth inning breaking a 2-2 tie to put the Yankees up 4-2, allowing Wandy Peralta and Clay Holmes to close the door with sharp pitching out of the bullpen.
Debutant pitchers make history
Two pitchers in their very first career start tossed at least six scoreless innings in shutout wins, with Ryne Nelson carrying the Arizona Diamondbacks to a 5-0 win and Hunter Brown delivering for the Houston Astros in a 1-0 result.
Nelson pitched seven innings, striking out seven batters while allowing four hits and one walk. Brown pitched six innings, giving up three hits and one walk while striking out five.
It is the first time in MLB history that two debutant starting pitchers delivered a scoreless outing with at least five strikeouts on the same day.
Tampa Bay Buccaneers head coach Todd Bowles has declared star quarterback Tom Brady is "all in" following his recent absence ahead of Week 1 of the new NFL season.
Brady returned to practice last month after an 11-day absence from the Bucs' training camp for "personal matters", with the Buccaneers due to take on the Dallas Cowboys on Sunday to open their season.
There has been speculation about Brady's absence impacting his focus on football but Bowles brushed that off.
"He's been all in since we got him," Bowles said. "He's all in now.
"I don't follow the off-the-field stuff. I listen to XM The Groove and Soul Town. My off-the-field activities are honestly not even football-related."
The questions emerged after an unusual off-season for Brady, who retired in February before reversing that decision 40 days later in March.
Brady last week declined to go into any depth on the personal matters behind his recent absence but said: "I'm 45 years old, man. There's a lot of s*** going on. Just gotta try to figure out life the best you can. It's a continuous process."
The seven-time Super Bowl champion said last week that he was "ready to go" and on Monday was named on of their offensive captains.
Aryna Sabalenka believes she is ready for the challenge of Karolina Pliskova in the quarter-finals after losing both of their meetings in 2021, saying she knows what to expect this time around.
Sabalenka defeated Danielle Collins 3-6 6-3 6-2 on Monday, with the world number six coming from a set behind to collect her seventh win from her past eight matches.
With Pliskova getting the better of Sabalenka's Belarusian compatriot Victoria Azarenka 7-5 6-7 (5-7) 6-2, it sets up the fifth career meeting between the pair, with their head-to-head record split at two wins apiece.
Sabalenka won both meetings in 2018, but after years without a match against each other, Pliskova flipped the script in 2021 with wins in Montreal and at Wimbledon.
Speaking to the media after her fourth round win, Sabalenka said she was caught by surprise at how much Pliskova had improved in the years between their matches, and how that will not be the case this time around.
"To be honest, on those matches, the first matches I won against her, I was an upcoming player," she said. "I was lower in the ranking, I was respecting every top player. I was kind of expecting a great level from them.
"Then, in the last two matches last year, I was in the top. Every time she was making me move, every time she was making winners, I was like, what's going on? How is it possible? Oh, my God, she is making winners.
"I want to say that I wasn't kind of really respecting her. Right now I really expect great level from her.
"It's going to be tough. Every time she will make some winners, it's not going to be pissing me off, it's going to be like, okay, it's normal, she's making it, what next?"
Meanwhile, Pliskova believes she is playing her best tennis of the season at the moment after advancing to the quarter-finals for the second straight year, having lost to Maria Sakkari at Flushing Meadows in 2021.
She told the media after defeating Azarenka that it may have been her best performance of the year – and maybe even longer.
"I think this was one of the best matches this year, from my side," she said. "I think also from her. I thought the level of the tennis was quite good for all three sets.
"Maybe in the third set, maybe she started to drop it a little bit. Of course, it was understandable because physically it was also quite tough. We had long rallies, long points, long games.
"But quite happy with my level. I think I'm playing quite good tennis now, maybe even better than last year here."
Baltimore Ravens quarterback Lamar Jackson is focused on playing according to head coach John Harbaugh despite no contract extension being agreed yet.
Jackson, who is entering the final year of his rookie contract, had previously indicated that he hoped to come to an agreement on an extension with the Ravens by a Week 1 deadline.
But the Ravens' season opener is fast approaching, with Baltimore up against the New York Jets on Sunday.
Harbaugh rejected any suggestion that Jackson would hold out on a new deal and insisted he was focused on playing for the Ravens after Monday's practice.
"Lamar has said he's focused on the season, he's under contract and he's going to have the best season he can have," Harbaugh told reporters.
"He's hopeful to get a new contract and we're hopeful to get him a new contract. All the rest of it is business. There is nothing other than coming to something that is mutually agreeable.
"That's the way that all of these deals are done. So, obviously, I'm very hopeful, and I know everyone is really hopeful to get it done."
The Ravens QB, who is representing himself without an agent, is set to make just over $23million guaranteed on his fifth-year option in 2022.
"I don't have any updates," Harbaugh said.
"My interactions with Lamar have been all football. He's been focused and locked in on that, 100 per cent, from a football standpoint."
The 32nd overall pick of the 2018 draft, Jackson is coming off an injury-marred 2021 season, averaging 240.2 passing yards and 63.9 yards rushing in 12 games.
He finished with 16 passing touchdowns, a career-high 13 interceptions and an 87.0 QB rating – eighth lowest among the 30 quarterbacks with at least 350 passing attempts last season.
The Ravens lost four of the five games Jackson missed last season and finished 8-9 to miss the playoffs for the first time in his career.
Frances Tiafoe is dreaming big after upsetting Rafael Nadal in the US Open fourth round on Monday to open up the men's singles draw.
The 22nd-seeded American stunned the 22-time grand slam champion, winning 6-4 4-6 6-4 6-3 in three hours and 34 minutes.
The victory meant Tiafoe reached the US Open quarter-finals for the first time, having fallen in the fourth round in the past three years. It also equaled his best-ever major return, having made the 2019 Australian Open quarters as well.
It also opens up the men's singles draw for a potential new grand slam winner, with Marin Cilic – who is due to play third seed Carlos Alcaraz on Monday evening – the last remaining major champion.
"Everyone is looking at it I'm sure," Tiafoe told reporters about the draw. "Everyone looks at it. Here we go, right? So am I. I'm just taking it day by day.
"Slams, crazy things can happen. Especially here in New York, so it's going to be a fun ride come Wednesday."
Tiafoe will take on ninth seed Andrey Rublev on Wednesday in the last eight, where he will hope to re-produce the "unbelievable" form he displayed against Nadal.
"I'm beyond happy, almost in tears, I can't believe it," Tiafoe said in his on-court interview. "I played unbelievable tennis today. I really don't know what happened."
During his press conference, he added: "It was definitely one hell of a performance… I just came out there and I just believed I could do it.
"It helps I played him a couple times. Haven't played him in some years [not since 2019]. I'm a different person now, different player."
Tiafoe had never beaten Nadal before, nor had he taken a set off the Spanish world number three. The victory was Tiafoe's third against a top-five opponent.
"For a while there, I was like, geez, you see all these young guys get Rafa, Fed [Roger Federer], Novak [Djokovic], am I ever going to be able to say I beat one of them?" he said.
"Today I was like, no, I'm going to do that. Now it's something to tell the kids, the grandkids, I beat Rafa."
Tiafoe was also blown away after four-time NBA MVP LeBron James tweeted after his win, labeling him the "young king".
"I was losing it in the locker room. I was going crazy," he said. "That's my guy, so to see him post that, I was like do I retweet it as soon as he sent it? I was like, you know what, I'm going to be cool and act like I didn't see it and then retweet it three hours later."
Rafael Nadal was frustrated by his performance when speaking with the media after his upset loss against Frances Tiafoe in the fourth round, admitting "he was better than me".
Nadal only allowed two total break point opportunities from the first three sets, but he was unable to save either, leading to Tiafoe taking the first and third frames.
The all-time leader in men's grand slams then was uncharacteristically shaky in the fourth, committing four double faults and more unforced errors (nine) than winners (seven).
While reporters questioned if it was the oppressive humidity, injuries, or even the distraction of the roof closing mid-match, Nadal made it clear his poor performance had a much simpler explanation.
"Well, the difference is easy," he said. "I played a bad match and he played a good match. At the end that's it, no?
"I was not able to hold a high level of tennis for a long time. I was not quick enough on my movements. He was able to take the ball too many times very early, so I was not able to push him back.
"Tennis is a sport of position a lot of times – if not, you need to be very, very quick and very young. I am not in that moment anymore.
"My shots need to be better. In some way my understanding of the game and the quality of my shots were not good enough. They were poor, I think I have to say today, because I was not able to create that much on him.
"Well done for him. He was better than me."
With the last grand slam of the year now in the books for Nadal, he said he will take some time away to recuperate, but was non-committal about when he may return.
"I need to go back [home], I need to fix things, life," he said. "Then I don't know when I'm going to come back.
"I'm going to try to be ready mentally. When I feel that I will be ready to compete again, I will be there."
After defeating Julie Niemeier in a less than inspiring showing, Iga Swiatek feels the race for the US Open title is wide open, and any of the women remaining in the quarter-finals can go all the way
In an uncharacteristic opening set from the world number one, Swiatek had her serve broken in the very first game, and conceded another break to drop the frame 6-2.
She fought back in the second as they traded breaks of serve, with only three successful holds from 10 games as Swiatek took it 6-4, before really finding her groove in the third to run away with a 6-0 finish.
It was her 19th 'bagel' set of the season, with only Serena Williams in 2013 (25) posting more 6-0 sets in a single year since 2000.
When asked about that record, Swiatek said she is aware of it, and that she enjoys Twitter memes referring to "Iga Swiatek's Bakery", although she did not wish to discuss any potential records.
Instead, she discussed the work she has been putting in on the hard courts, having never made the US Open quarter-final before this run.
"For sure, hard court is our goal at the beginning of the season, not the end of the season," she said. "Also we're mainly practicing on hard court pre-season.
"These are the courts that basically are going to show me where my level of tennis is.
"I played too many matches this year to get, like, huge excitement honestly. But for sure today I'm the most excited because the quarter-final is my best result right now.
"I'm just happy that I did a better job than last year and I'm going to push forward."
Swiatek was complimentary about her next opponent, Jessica Pegula, admitting "she has a game style that suits these courts", but she pointed out how many emerging players are on the tour at the moment and how it may simply come down to who can handle the big moments.
"I guess it's going to show who's going to cope with being in a new situation better," she said.
"But I think it's just exciting for all of us. It also shows that anything can happen, and anybody can win this tournament."
The Green Bay Packers have a good chance of getting a former All-Pro back on the field for their season-opening road game against the Minnesota Vikings on Sunday.
Left tackle David Bakhtiari, who has been rehabilitating from a serious knee injury since the end of the 2020 season, told ESPN Monday that he is ready to start in week one.
"Yeah, I mean, I'm on the active (roster) just like anyone else," Bakhtiari said.
The three-time Pro Bowl selection began the Packers’ offseason on the physically unable to perform list but has been a full participant in recent practices, including 11-on-11 workouts.
Bakhtiari, 30, originally suffered a torn left ACL on Dec. 31, 2020, and has undergone three surgeries on the knee since.
He returned briefly to the field in Week 18 last season, playing 27 snaps in Green Bay’s regular-season finale before experiencing complications and being shut down for the postseason.
After 20 months of working to return to protecting Aaron Rodgers’ blindside, Bakhtiari believes he is ready to once again anchor the Packers’ offensive line.
"I can get through the season," Bakhtiari said. "It's going to be fine. You have to just manage while playing.
"I'm just getting back in the swing of things. So, I mean, I think there's normal rust and then new normal with three surgeries, so just kind of working that out and figuring out what my routine is."
Green Bay’s second-most decorated offensive lineman, Elgton Jenkins, remains a question mark as he is working his way back from his own ACL surgery.
Head coach Matt LaFleur was noncommittal on the possible return of Jenkins, a 2020 Pro Bowler.
"We'll have to find out on Sunday," LaFleur said.
Frances Tiafoe produced a stunning performance to knock Rafael Nadal out of the US Open and reach the quarter-finals of his home grand slam for the first time.
Tiafoe was playing in the fourth round at Flushing Meadows for the third successive year, but his prospects of going beyond that point appeared slim against the 22-time grand slam champion.
Nadal had won his two previous encounters with Tiafoe but found the 24-year-old up to the challenge this time around, his firepower proving too much for his illustrious opponent.
So often Nadal has snatched victory from the jaws of defeat and there were moments during his epic that he seemed primed to do so again. Yet winning the second set and breaking at the start of the fourth both proved false dawns for Nadal, as Tiafoe prevailed 6-4 4-6 6-4 6-3 to blow a men's draw that has already lost 2021 champion Daniil Medvedev wide open.
It became clear early on that the pace of Tiafoe's ball-striking and the variety in his game would cause Nadal problems and he got the break his play deserved when the Spaniard sent a pair of forehands long in the seventh game.
Tiafoe rarely looked daunted by the occasion and though he let a pair of set points go begging after going 40-0 up at 5-4, he snatched the third with a volley to ensure Nadal would have to mount a comeback.
A classic Nadal turnaround appeared very much on the cards when Tiafoe's composure deserted him trailing 5-4 on serve in the second, a double fault from the American allowing Nadal to level the match.
But any thought of Nadal, curiously unable to make an impression on Tiafoe's second serve, dominating from there was soon extinguished, Tiafoe breaking for a 4-3 lead in the third with a searing backhand down the line.
Tiafoe consolidated with an intelligent serve and volley play on his second serve and, after a Nadal hold, made no mistake in winning the third set on his racquet with an ace.
Controversy soon followed as Nadal broke a furious Tiafoe with a vicious forehand in a game played as the Arthur Ashe Stadium roof was closing.
Tiafoe received a code violation for "audible obscenity" after venting his frustration at that decision by the tournament officials, but he harnessed his anger in the right way. Nadal sent down a pair of double faults in an uncharacteristically sloppy service game and Tiafoe capitalised with a cross-court backhand that proved too hot for the four-time champion to handle.
A backhand error from Nadal gave Tiafoe another break for a 4-3, and he subsequently raced to the finish line, getting 40-0 on Nadal's serve and then completing the fairytale with on his second match point as Nadal sent another backhand into the net.
Data Slam: Tiafoe hands Nadal first grand slam loss of 2022
After winning both the Australian Open and the French Open, and withdrawing from Wimbledon due to injury, this is Nadal's first loss at a grand slam this year.
Tiafoe also joins James Blake and Andy Roddick as the only Americans to ever defeat Nadal at a grand slam, and it snaps Nadal's streak of 16 consecutive grand slam quarter-final appearances.
ACES/DOUBLE FAULTS
Tiafoe – 18/4
Nadal – 9/9
WINNERS/UNFORCED ERRORS
Tiafoe – 48/28
Nadal – 33/26
BREAK POINTS WON
Tiafoe – 5/8
Nadal – 2/6
The New York Jets' season kicks off in six days and coach Robert Saleh is still leaving the door open for Zach Wilson to start the opener.
"Yeah, it's possible," Saleh said on Monday.
Saleh told reporters Wilson threw some passes and tested his right knee during a workout on Monday and a decision will be made in the next few days to see if he will be healthy enough to start on Sunday against the Baltimore Ravens.
"We put Zach through a workout today," Saleh said. "Looked good, felt good. We're going to see how the knee responds today and tomorrow, and we'll have an answer for everyone on Wednesday."
Wilson suffered a bone bruise and torn meniscus in his knee while scrambling in the Jets' preseason opener against the Philadelphia Eagles on August 12, and the original diagnosis was he would be sidelined for two to four weeks.
That timeline remained the same after the second-year quarterback had successful arthroscopic surgery on August 16 in Los Angeles.
"Everyone heals differently," Saleh said. "Like I said, we'll see what happens tomorrow and all that stuff.
"I almost feel like some of the guidelines that are put on, they're guidelines, but everyone responds differently."
The Jets plan to be cautious with the 23-year-old, who they selected second overall in last year's draft, as they hope he will be the franchise's long-term answer at quarterback.
If he cannot play, Joe Flacco will get the start in Week 1 against his former team.
Iga Swiatek survived a major scare as she came from a set and a break down to beat Jule Niemeier and set up a US Open quarter-final with Jessica Pegula.
The world number one looked to be in a real spot of bother against the German ranked 107 places below her, but Niemeier could not maintain her blistering start and Swiatek claimed a 2-6 6-4 6-0 victory.
Swiatek initially looked a shadow of the player who had not lost a set in the first week, with Niemeier's power and unpredictability causing the Pole no end of issues.
Niemeier was immediately a break up and had no problem consolidating before eventually getting another to lead 5-2.
So underwhelming was Swiatek that Niemeier could even afford three double-faults in the final game of the opener as the German impressively took a first-set lead.
After a bathroom break, Swiatek returned with greater purpose but was still lacking ruthlessness; she inexplicably missed a forehand on break point at 1-0 up in the second, and then she stuck a simple volley into the net a few minutes later to find herself a break down.
That was the first of seven breaks in a second set defined by poor serving, but Swiatek was just slightly better than her opponent, with successive breaks giving her the edge in a rollercoaster encounter.
From there, Niemeier barely registered as a threat due to her wastefulness, recording four double-faults and 14 unforced errors to Swiatek's zero and one respectively in the decider as the latter bageled her opponent.
Tyson Fury has taken to social media to offer Antony Joshua a WBC heavyweight championship fight amid delays to his plans to face Oleksandr Usyk in a unification bout.
Fury has made several U-turns on his decision to retire following a sixth-round stoppage of Dillian Whyte in April, and has been widely touted to be Usyk's next opponent following his split-decision win over Joshua in Jeddah last month.
But the Ukrainian is reportedly ready to wait until 2023 for his next bout, leading Fury to vow he would "wait around for nobody" on Sunday.
Fury, who has 32 wins and one draw from his 33 professional fights, promised to announce a new opponent within the next few days, and the 34-year-old appears to have his sights set on Joshua.
"Tyson Fury here, aka the Gypsy King, the WBC heavyweight champion of the world, as you can tell," Fury said in a video posted to Instagram, wearing his belts.
"I think you've all heard that I'm going to be fighting soon, within the next few months, and I think that before I announce an opponent, I need to do this, just in case.
"Anthony Joshua, I know you've just lost a fight to Usyk and you're beltless at the moment, and I'd like to give you an opportunity to fight me for the WBC heavyweight championship of the world in the next few months.
"You're coming off a 12-round fight, so you're match-fit, you're ready.
"I'm giving you a few months notice, if you're interested I'll send you the date over and we can have a rumble, a battle of Britain for the WBC championship.
"Let me know if you're interested. If not, I will select another opponent. Thank you very much, and good night."
A bout between Fury and Joshua has been rumoured for several years. Should it be arranged, it would represent a huge chance at redemption for Joshua, who had lost three of his last five fights after winning each of his first 22.
Mercedes team principal Toto Wolff believes Yuki Tsunoda's mid-race stoppage at the Dutch Grand Prix may have cost Lewis Hamilton a shot at victory over Max Verstappen.
The Briton looked on course for a first win of a difficult season, having seldom been near the pace of his Red Bull rival following last year's enthralling title battle.
But a virtual safety car stoppage for Alpha Tauri's Tsunoda two-thirds into the race handed Verstappen a free pit stop, before a physical safety car later on allowed the world champion to make another change and overtake Hamilton.
Tsunoda stopped his car after reporting issues with his tyres, removing his safety belts before being ordered to drive back to the pits. His belts were checked and he drove for four more corners, before being told to stop again by his team.
Hamilton was ultimately forced to settle for fourth, behind Verstappen, team-mate George Russell and Ferrari's Charles Leclerc.
Red Bull principal Christian Horner suggested the stoppage of Tsunoda had no effect on the outcome of the race, but Wolff felt the decision to send the Alpha Tauri – Red Bull's sibling team – back out likely cost Hamilton.
"If we were to fight for a championship, that would be something I would closely look at," he stated when asked if the FIA should review the incident.
"Now, I think what needs to be investigated for the safety of drivers and everybody out there.
"The driver stopped, unbuckled, did a full lap, came in, the problem wasn't solved, they put the seatbelts back on and he drove out and stopped the car again.
"That probably has changed the outcome of the race that we maybe could have won.
"I think we would have had a fair shot at the win. The race planner said the win was on. It was very close, but it was on."
Daniil Medvedev knows he has not performed to the best of his abilities at grand slams this season after his US Open title defence was ended by Nick Kyrgios.
Medvedev, who will also concede his spot at the top of the ATP's world rankings, has only won one of the four finals he has reached in 2022.
His record in the majors is a particular frustration for the 26-year-old. After losing to Rafael Nadal in the Australian Open final, Medvedev has reached the fourth round at Roland Garros and the same stage at Flushing Meadows, while The All England Club's ban on Russian and Belarusian athletes prevented him from competing at Wimbledon.
With Novak Djokovic unable to play in New York due to his COVID-19 vaccination status, Nadal, Carlos Alcaraz or Casper Ruud will become the world number one after the US Open's conclusion on Sunday.
"I mean, now that you say it, I remember it," Medvedev said in a press conference when asked how it felt to give up the number one spot.
"That's not nice because honestly after such a match, when you lose in a grand slam... I'm trying to look good here, but I'm disappointed.
"[I'm] not going to cry in the room, but I'm a little bit disappointed. For a few days I'm going to be just a little bit sad, looking at my phone, my laptop or watching some series.
"Yeah, it was not the first thing on my mind walking after the match, saying, 'Damn, I will not be the world number one anymore' – I actually don't know which place I will be. Probably three or four. I guess Carlos will pass me. I don't know actually.
"But that's motivation, try to do better. Obviously it was the last slam of the year. I didn't do well enough. Didn't win in Australia when I had the chance. Didn't get the chance to play at Wimbledon.
"Roland Garros, lost in the fourth round. Here, fourth round. Yeah, I should do better, should get more points if I want to be world number one again."
Medvedev went down 7-6 (13-11) 3-6 6-3 6-2 to Kyrgios, who has a 4-1 winning record against the Russian.
Asked if he thought it was Wimbledon finalist Kyrgios' best display against him, Medvedev suggested the Australian came close to replicating the form of greats Nadal and Djokovic.
"Yeah, it was a high-level match," he said. "[I] played Novak, Rafa. They all play amazing. Nick played kind of their level, in my opinion.
"He has a little bit different game because he's not a grinder in a way, [but] at the same time he can rally. He's tough to play.
"He has an amazing serve. He plays well, has every shot. It was a really high-level match from him.
"If he plays like this until the end of the tournament, he has all the chances to win it, but he's going to get tough opponents."
Coco Gauff dispatched Zhang Shuai in straight sets to become the youngest US Open quarter-finalist in 13 years.
The 18-year-old American fan favourite won 7-5 7-5 on Sunday, sealing her place in the last eight.
Gauff's victory makes her the youngest player to have reached the quarters at Flushing Meadows since Melanie Oudin in 2009.
Oudin, another American, was 17 at the time, and lost her last-eight tie to eventual runner-up Caroline Wozniacki.
Caroline Garcia is next up for Gauff, who will face either Ons Jabeur or Ajla Tomljanovic should she overcome the US Open quarter-final debutant.
Australia's Tomljanovic followed up her defeat of Serena Williams with a 7-6 (10-8) 6-1 win over Liudmila Samsonova, snapping the Russian's 13-match winning streak and reaching her second career grand slam quarter-final in the process.
World number five Jabeur, meanwhile, made history by becoming the first North African woman to make the US Open quarter-finals in the Open Era.
She is the third woman from the African continent to do so, with South Africans Maryna Godwin (1968) and Amanda Coetzer (1994, 1996 and 1998) having previously achieved the feat. Jabeur defeated Veronika Kudermetova 7-6 (7-1) 6-4.
Los Angeles Rams quarterback Matthew Stafford says there are "no limitations" on his right elbow ahead of the NFL season opener against the Buffalo Bills on Thursday.
The 34-year-old played through the pain as he helped the Rams to victory at Super Bowl LVI against the Cincinnati Bengals earlier this year.
Stafford required a mid-term injection to continue and did not throw during workouts in the spring, with a specific throwing schedule during the Rams' training camp.
But he has revealed he is ready for the new campaign, and says there will be nothing to hold him back, stating: "I feel good. I'm ready to go, no limitations.
"I feel great. I'm ready to go play. [You] can always be better, can always try to feel like [you're] 21 again. But no, I feel really good. I feel like I can make every throw."
Rams coach Sean McVay echoed Stafford's comments, adding: "He's throwing the ball excellent. He feels good. Everyting that I'm seeing is reflective of everything he's saying to me."
Stafford will be looking for another strong regular season in his second year with the Rams, after throwing 41 touchdowns prior to last season's playoffs, the joint-best of his career to date (also 41 with the Detroit Lions in 2011).
Nick Kyrgios took the opportunity to discuss the low points of his career after his victory over Daniil Medvedev, admitting he never thought he would have the chance to return to his best form.
Kyrgios conceded just one set to Medvedev in the 7-6 (13-11) 3-6 6-3 6-2 triumph at the US Open on Sunday.
It appeared during the first set tiebreaker that he was on the verge of one of his famous meltdowns, with a couple of racket slams and plenty of abuse towards his own box, but he steadied and fought back after a poor second frame.
Speaking to the media after the match, Kyrgios admitted the tiebreaker was do-or-die, saying: "I feel like if he'd got that first set, it was going to be pretty much an impossible task for me to come back and win."
This year's Wimbledon runner-up was humble and respectful when discussing the talent of Medvedev, and despite his muted celebration, highlighted what a big deal it is for him to perform well under the bright lights in New York.
"I didn't over-celebrate. It's only the fourth round, I've got quarter-finals [next]," Kyrgios said. "But it was an amazing experience obviously taking down the number one player in the world on Arthur Ashe Stadium.
"I don't really like to celebrate too much after that because I know that if I played him nine more times, he's probably getting on top of me the majority of the time.
"I hadn't won a match on Ashe before this week, now I've won two against two quality opponents, and I feel like I've been able to showcase [my talent].
"There's a lot of celebrities here, a lot of important people here watching. I wanted to get on that court and show them I am able to put my head down and play and win these big matches.
"For the tennis world I think it's important as well. People were really starting to doubt my ability to pull out matches like this at majors. I'm really proud of myself honestly because it hasn't been easy dealing with all the criticism."
Kyrgios continued to discuss how he feels he is perceived by the public and the media, saying it was more a feeling of relief than ecstasy when he finished the job.
"I feel like I'm more just proud of the way that I've bounced back after everything, honestly," he said. "I've been in some really tough situations mentally, and in some really scary places.
"Obviously if you look at it on paper, I probably wasn't expected to win that match. Maybe take a set or two if I'm lucky, give the people a show.
"It's a great win, but I come off the court and I'm just almost relieved that it's over because there's just so much pressure every time I go out on court, so much expectation, so much unpredictability of what I can do.
"I just sit there in the locker room after and I'm just super proud of the performance, because there was really a time where I didn't think I was capable of producing and doing this any more.
"I guess I'm just more relieved, and I'm super proud."
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