Rafael Nadal's loss to Frances Tiafoe opened up a host of possibilities including a first-time world number one and maiden grand slam winner as the top three's domination of men's singles continues to weaken.
World number three Nadal bowed out in the fourth round to 22nd seed Tiafoe 6-4 4-6 6-4 6-3 on Monday, while third seed Alcaraz triumphed over Marin Cilic 6-4 3-6 6-4 4-6 6-3 in a match that went to almost 2:30am local time.
Cilic was the last remaining male player with a grand slam title to his name, meaning this year's US Open will bring a new major champion.
There may also be a first-time world number one too, with Alcaraz guaranteed to claim the top rank if he wins the US Open title.
Fifth seed Casper Ruud will rise to world number one if he lifts the US Open crown at Flushing Meadows on September 11 too.
If both fall short of the final, Nadal will reclaim the top ranking from 2021 US Open champion Daniil Medvedev, who lost in the fourth round to Nick Kyrgios.
Alcaraz could also scale the rankings summit should he reach the final, assuming Ruud misses out.
ATP Finals: Sinner stays perfect with assured Fritz victory
Jannik Sinner continued his quest to end his stellar season with the ATP Finals title after downing Taylor Fritz in straight-sets to earn his second win of the tournament.
Sinner emerged a 6-4 6-4 victor in an hour and 40 minutes in Turin, with his latest triumph improving his record to 7-0 on indoor hard courts in 2024.
The Italian showed his intentions with a love service game to open the first set, but was matched by his American opponent, who was also looking to maintain his perfect start.
Sinner missed four break points in the eighth game, but made no mistake in Fritz's following service game to claim the early advantage in Turin.
Fritz again traded blows with the year-end world number one, but would again lose a decisive break late in the second set that put Sinner within touching distance.
The American exchanged in another pulsating rally with his opponent, but sent a backhand wide to send Sinner through and to the top of the Ilie Nastase Group after two matches.
Up next for Sinner is Daniil Medvedev, who beat Alex de Minaur earlier on Tuesday, while Fritz will face the Australian on Thursday.
Data Debrief: The Italian Job
In a back-and-forth tussle with Alexander Zverev to end the year with the most wins, Sinner levelled the German with his Tour-leading 67th victory in 2024 on Tuesday.
He also sealed a 12th win against an American opponent this season, only managing more wins against Ben Shelton (three) this season than Fritz (two, level with Alex Michelsen).
Sinner (2023-24) is only the third player in the Open Era to claim 47+ ATP match wins on hard court in consecutive seasons after Roger Federer (2005-06) and Novak Djokovic (2012-13, 15-16).
Daniil Medvedev credited his ability to "block out the noise" as crucial in getting his ATP Finals campaign up and running with a straight-sets victory over Alex de Minaur.
Medvedev, who lost his opening game of the tournament to Taylor Fritz, returned to winning ways with a 6-2 6-4 triumph over the Australian in 78 minutes on Tuesday.
The Russian cut a frustrated figure in his defeat to Fritz on Sunday, breaking his racket and was docked a point after serving a third consecutive double fault during the encounter.
However, the fourth seed produced an expertly measured performance, winning 20 out of 31 baseline points in the opening set to claim the early advantage.
The second set was more evenly contested, but Medvedev secured a crucial break point in the ninth game, going on to seal his first top 10 win on hard courts since March.
"After the last match I was too tired to fight mentally the way I do and so, during the match, when it doesn't work your way, you want to win and when you start losing you get frustrated," Medvedev said.
"So I went into this match thinking, if I lose I go home on Thursday for sure and if I win then I have the chance to have a good feeling. I tried to hit some shots and it worked well and I'm ok with it.
"A lot of football players do it [block the noise]. It's more about social media and for sure after my performance with Taylor and some of my comments ... I tried to read it less.
"I went into this match trying to block the noise even from myself, so no tantrums and I really didn't care what was happening on the court."
Medvedev will seek to bolster his hopes of progressing from the John Newcombe Group when he takes on Jannik Sinner next, with the Italian in action against Fritz later on Tuesday.
Data Debrief: Cool, calm and collected
Medvedev kept his hopes of sealing a second ATP Finals crown alive with a composed display against De Minaur, improving his record to 45-19 for the season.
While the Russian produced more unforced errors (18) than De Minaur (15), Medvedev showed his quality by hitting 24 winners, 14 of which came with his forehand.
Medvedev also claimed his sixth top 10 win of 2024, while also improving his head-to-head record against his Australian opponent to 7-3, avenging his defeat in the French Open round of 16 earlier this year.
Osaka has set sights on grand slam title – Mouratoglou
Naomi Osaka is targeting a fifth grand slam win of her career, so says Patrick Mouratoglou.
Osaka, who has won the Australian Open twice and the US Open twice, will head into 2025 as the world number 59.
The former world number one has had a stop-start career in recent years, as she took time away from the sport to focus on her mental health, before then giving birth.
She has taken part in 18 WTA Tour-level competitions this season, with her best effort a run to the quarter-finals at the Qatar Open in February.
Mouratoglou, a former coach of Serena Williams, has been helping to guide the 27-year-old, and he explained Osaka has set her sights on another major crown.
"[With] Serena, motivation was extremely key after she beat the record of [Martina] Navratilova and Chris Evert [to reach 23 Grand Slam singles titles]," he told Sky Sports.
"But I think we worked so well together because I think we were both motivating each other all the time. I knew exactly how to talk to her. She knew exactly how to talk to me. I was pushing her, she was pushing me and that was like that every day.
"So that's why it works so well. For Naomi, it's different because she really feels she has to give and do much more. She had two very difficult years.
"First, she had this mental health issue, and then she had a baby. So she's been out, and then she restarted the year this season and it was not a very good season.
"Before the first tournament we did together she was 80 in the world and she knows she can do much better than that.
"She's extremely motivated to come back and win grand slams, and it's a pleasure for me because that's the dream of every coach: to have a player who has that level of motivation."
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