Daniil Medvedev and Stefanos Tsitsipas progressed to the third round of the Madrid Open but there was no such luck for Felix Auger-Aliassime on Saturday.

Second seed Medvedev cruised past Italian qualifier Andrea Vavassori 6-4 6-3, teeing up a meeting with Alexander Shevchenko, who overcame Jiri Lehecka in straight sets.

Tsitsipas was made to work by Dominic Thiem, but the fourth seed battling from a set down to win 3-6 6-1 7-6 (7-5).

World number 40 Dusan Lajovic provided the shock of the day by defeating seventh seed Auger-Aliassime 6-2 3-6 7-6 (7-5).

Denis Shapovalov, the 21st seed, was another surprise second-round loser, falling 6-7 (4-7) 6-4 7-6 (7-1) to China's Zhang Zhizhen.

Taylor Fritz avoided adding to the list of notable early eliminations in the Spanish capital, the eighth seed battling to a 7-6 (13-11) 6-4 victory over Christopher O'Connell.

Fritz's fellow American Frances Tiafoe progressed with a 6-3 7-6 (7-5) triumph over Argentina's Tomas Martin Etcheverry, while 14th seed Tommy Paul crashed out after a 6-3 7-6 (7-3) defeat to Roman Safiullin.

Seeds Alex de Minaur and Sebastian Baez also navigated their way through to the third round, defeating Marco Cecchinato and Marcos Giron respectively, as did Cameron Norrie at the expense of Yosuke Watanuki.