Arizona Cardinals wide receiver DeAndre Hopkins is to be suspended for six games by the NFL for violation of the league's performance-enhancing drug policy, according to reports.

The 29-year-old required MCL surgery after suffering a knee injury in December's 30-23 defeat to the Los Angeles Rams, missing the remainder of the 2021 campaign, including the Wild Card playoff loss to the Rams.

According to ESPN's Adam Schefter, the Cardinals will be without Hopkins for the opening six games of the season due to his suspension, which is final after he withdrew his appeal.

The Cardinals traded on draft day for another wide receiver, Marquise Brown, having lost Christian Kirk after the 25-year-old signed a $72million contract with the Jacksonville Jaguars.

In the 10 games he did play in last season, Hopkins – a three-time first-team All-Pro and five-time Pro Bowl selection – managed 42 receptions for a total of 572 yards, with eight touchdowns to his name.

In the 2020 season, his first with Arizona after being traded by the Houston Texans, he recorded 1,407 yards from 115 receptions, and six TDs.