Indianapolis Colts running back Jonathan Taylor exited Saturday’s game against the Minnesota Vikings with a right ankle injury and was ruled out for the rest of the contest.

Taylor suffered the injury on the Colts’ first possession of the game on a 13-yard reception.

The leading rusher in the NFL last season, Taylor has battled ankle soreness all this year and has missed three games this season due to ankle issues.

Taylor entered Week 15 ranked 11th in the league with 861 rushing yards in 10 games. His 86.1 rushing yards per game this season ranks fourth in the NFL.

The injury left Zack Moss and Deon Jackson to handle duties in the backfield as the Colts looked to avoid a seventh loss in their last eight games.