The neutral has plenty to be thankful for in this thrilling 2021 NFL season.

But all that drama, driven by a series of stunning against-the-odds upsets, can make life miserable for fantasy players, even at this celebratory time of year.

Want to maintain your cheer through another seemingly unpredictable slate of games this Thanksgiving week? Turn to Stats Perform for the below data-powered picks.

Quarterback: Jalen Hurts, Philadelphia Eagles @ New York Giants

The Eagles head into Week 12 rejuvenated, having won three of their past four games to improve to 5-6 ahead of a big NFC East matchup. Those three wins have all had one thing in common: Philadelphia have exceeded 200 yards rushing.

This run-heavy approach – with a league-high 49.6 rush percentage – wisely plays to the strengths of quarterback Hurts, who had three rushing scores last week against the New Orleans Saints as he surpassed 50 yards on the ground for the fifth straight game.

That was Hurts' 15th QB start. He ranks second through 15 QB starts since 1950 for rushing touchdowns (11 – behind Cam Newton, 14) and second through 15 QB starts since 1960 for rushing yards (890 – behind Lamar Jackson, 1,193).

The Giants – reeling from a bad defeat to the Tampa Bay Buccaneers – have given up 4.38 yards per rush play, ranking a mediocre 19th, and have not yet played any of the six best offenses in that regard. The Eagles' offense (4.99 yards per rush), led by Hurts, sits third and will be eyeing further big gains.

Running back: Joe Mixon, Cincinnati Bengals vs. Pittsburgh Steelers

Mixon is already enjoying a career year with nine rushing TDs, and the 2021 season might be about to get a whole lot better for the running back – and any fantasy players who can count on him – as the Bengals face an injury-ravaged Steelers defense.

Pittsburgh have now given up the most yards per rush play (4.76) after a tough two weeks in which their roster was hit by absences and it showed on the field. The winless Detroit Lions tallied 229 rushing yards and two TDs in their Week 10 tie, before the Los Angeles Chargers averaged 6.12 yards per rush as Austin Ekeler's two scores headlined a Week 11 win.

Mixon, who has rushing TDs in four straight games and last week ran for over 100 yards for the first time since Week 1, should get free rein against a Steelers defense that successfully disrupts the run on just 24.62 per cent of attempts.

Even if Pittsburgh can fix a problem that has persisted throughout the season and got worse of late, Mixon ranks 12th among running backs (min. 10 carries) with 3.74 yards per carry on disrupted runs.

Wide receiver: Deebo Samuel, San Francisco 49ers vs. Minnesota Vikings

A significant shift towards a run-heavy approach – the 49ers averaged 25.6 rushes per game through Week 9 but 43.0 per game since – would be an issue for most wide receivers, but Samuel is not most wide receivers.

It is his versatility that has helped accommodate a change that has potentially brought San Francisco back into contention.

Samuel caught only one pass against the Jacksonville Jaguars last week but rushed for 79 yards and a TD in the absence of injured rookie Elijah Mitchell. The previous week, with Mitchell involved against the Los Angeles Rams, Samuel had rushing and receiving scores in the same game for the first time in his career.

With the Vikings' rush defense matching the Steelers' in giving up 4.76 yards per rush, expect Samuel and the Niners to run the ball again and do it well.

Tight end: Kyle Pitts, Atlanta Falcons @ Jacksonville Jaguars

Pitts is the sixth-most targeted tight end this season (69) but has the third-most receiving yards (635), boosted massively by 100-yard games against the New York Jets and the Miami Dolphins either side of the Falcons' Week 6 bye.

The schedule slowed that momentum somewhat – Atlanta were held to three points across defeats to the Dallas Cowboys and the New England Patriots – but a trip to Jacksonville gives Pitts the opportunity to put his name up in lights once again.

The Jaguars have given up 7.20 yards per pass play in 2021, meaning this is unlikely to be the defense to keep Pitts in check. He has got open on 34.41 per cent of his 93 matchups, up on the tight end average of 18.10 per cent.

Defense: New England Patriots vs. Tennessee Titans

The Titans head into this week as the top seed in the AFC, but the Patriots may well take that spot from them over the next two weeks, hosting Tennessee before going to the Buffalo Bills in Monday Night Football.

While Mac Jones is enjoying a fine rookie year at QB, it will be New England's defense that puts them in contention, having given up only 5.07 yards per play while securing 21 total takeaways – ranking third in both regards.

And the Pats will expect to dominate the Titans, whose injury list has only grown since Derrick Henry went down. A.J. Brown is the latest offensive weapon to be unhealthy, while Julio Jones is not expected back for another two weeks.

These problems contributed to a woeful defeat to the Houston Texans last time out, when Ryan Tannehill threw four picks. Elsewhere in Week 10, New England caught four interceptions against the Falcons.

Dallas Goedert has agreed a four-year contract extension with the Philadelphia Eagles, who recently traded star tight end Zach Ertz to the Arizona Cardinals.

The departure of Super Bowl-winning hero Ertz last month cleared the path for Goedert to take up the number one tight end spot for Philadelphia.

And the Eagles have made sure he will be around for his prime after confirming they have reached agreement on a deal that keeps him with the team until 2025.

According to NFL.com, the pact is worth $57million including $35m guaranteed.

Those terms ensure Goedert is the tight end with the third-highest average annual salary in the NFL, behind only George Kittle and Mark Andrews, while it is ahead of the Kansas City Chiefs' Travis Kelce.

"We're really excited for him," Eagles coach Nick Sirianni said on Friday. 

"He's the type of guy that we think the world of. He's a great football player, great on and off the field. 

"Just the type of guy you want to succeed and sign contracts like this and keep in the building."

Goedert, who was drafted in the second-round ahead of the 2018 season, has 29 receptions for 429 yards and two touchdowns in nine games so far this year.

He is averaging 14.8 yards per reception in 2021, which is second only to David Njoku (16.0) among NFL tight ends.

Goedert has remarkably recorded a first down with 75.9 per cent of his catches this year - which is the best rate at his position - and he ranks fourth with 6.8 yards after the catch.

The Eagles are at home against the 5-4 New Orleans Saints on Sunday. Having won two of their last three games to reach 4-6, they remain in contention for a Wild Card place in the NFC.

Miles Sanders is closing in on a return to action for the Philadelphia Eagles, who have activated the 21-day practice window for the running back.

An ankle injury suffered in the Week 7 loss to the Las Vegas Raiders landed Sanders on injured reserve.

He remains on IR but the roster move by the Eagles means he would be allowed to return to action this week if he is deemed to have made sufficient progress.

The Eagles are at home against the 5-4 New Orleans Saints on Sunday and head coach Nick Sirianni has told reporters there is a chance Sanders will be available.

The NFC East team have won two of their last three games to reach 4-6, ensuring they remain in contention for a Wild Card place.

Sanders was a second-round draft pick in 2019 after a college career at Penn State and was averaging 4.76 yards per carry this season before going down against the Raiders, having topped 800 yards in each of his first two years in the league.

Jordan Howard and Boston Scott have supported mobile quarterback Jalen Hurts in helping Philadelphia cope well with Sanders' absence – the Eagles lead the league with 208.7 rushing yards per game since Week 8, per NFL.com

The Saints game will be an intriguing battle. The Eagles have the third-best rushing attack with 144.3 yards per game, while Sean Payton's team are allowing only 72.9 YPG on the ground – which is the best mark in the NFL.

Hurts has been highly effective as a runner and 20.6 per cent of his rushes going for 10 or more yards represents the best mark of any qualifying player in 2021.

He has also rushed for a first down on 39.2 per cent of his carries, a ratio second only to the Buffalo Bills' Josh Allen.

Teddy Bridgewater acknowledged he "failed" the Denver Broncos when he "didn't give everything" on Darius Slay's 83-yard fumble return for a Philadelphia Eagles touchdown.

The Broncos headed into Week 10 on a high after a win at the Dallas Cowboys in which quarterback Bridgewater threw for 249 yards and a touchdown.

But that momentum was sapped by a defeat to another NFC East team on Sunday, with Denver coming up well short in a 30-13 defeat.

Bridgewater struggled to get the ball moving back at home, averaging 6.28 yards per attempt. He has advanced 6.4 yards per attempt in losses this year, versus 8.65 yards per attempt in wins.

But it was what Bridgewater did without the ball that attracted the most attention, as the former Carolina Panthers QB was widely criticised for his role in Slay's score at the end of the third quarter.

Davion Taylor knocked the ball free as Melvin Gordon attempted to get to ground on fourth and one, with Slay recovering the fumble and then running right by Bridgewater, who made no attempt to halt his opponent, en route to the endzone.

Bridgewater reflected on the episode on Monday and accepted he did not come out of it at all well.

"It definitely was [the toughest film session to sit through], especially when you slow it down," he said.

"In real time, it's like everything's happening fast, you've got the sideline to your advantage... and then when you slow it down with the clicker in your hand, it's like man, this is bad.

"Hopefully I never have to be put in that situation again, and if I am, make sure that I lay it all on the line.

"If I am, I'm going to make sure I lay it all on the line. I won't be the talk of social media or the internet or whatever. Hopefully we can just but this behind [us] and move forward."

Bridgewater added: "I'm right there, the opportunity to just dive, sacrifice, do whatever I can to help the team in that moment.

"I failed. And I owned up to it. It's unacceptable as a football player, as a member of this team.

"We play this game, and you lay it all on the line every week, and that's one of those moments where I've just got to accept the fact that I didn't give everything I had in me on that play.

"I understand, man; there's going to be some backlash that comes with it. I'm a grown man. I'm a professional athlete. I understand that's what comes with it – backlash and things like that.

"It doesn't define who we are as a football team, it doesn't define me as a man and as a football player."

The Green Bay Packers' first look at life without Aaron Rodgers was not a pleasant one, as their offence sputtered with backup quarterback Jordan Love at the helm and the Kansas City Chiefs held on for a 13-7 victory. 

The Packers (7-2) had averaged 27 points during the seven-game winning streak that ended on Sunday after reigning MVP Rodgers missed the game following a positive coronavirus test during the week. 

The visitors did not get on the scoreboard until Love hit Allen Lazard for a 20-yard touchdown pass with five minutes remaining for his first career NFL TD.

That gave Green Bay some hope after their previous drive had ended with L'Jarius Sneed picking off a Love pass on Kansas City's five-yard line, but the Packers ran out of time. 

While the Chiefs (5-4) were not about to complain about the victory that got them back over .500, their season-long concerns about their offence continued as Patrick Mahomes had another unimpressive game. 

Former league MVP Mahomes completed 20 of 37 passes for just 166 yards but avoided throwing an interception for the first time since the season opener. His 54.1 completion percentage was his worst in a regular-season game since completing 51.2 per cent in a loss to the Las Vegas Raiders in Week 5 last season. 

 

Cardinals cruise past 49ers without Murray

The other red-hot team playing without their star quarterback fared better, as the Arizona Cardinals rolled to a 31-17 defeat of the San Francisco 49ers despite Kyler Murray's absence through an ankle injury. 

Veteran Colt McCoy stepped in for the Cardinals and completed 22 of 26 passes for 249 yards, while James Conner rushed for 93 yards and a pair of scores as Arizona improved to 8-1. 

Three turnovers proved critical for San Francisco (3-5) as the 49ers lost two fumbles in the first half and had trouble sustaining drives throughout the game, with only 23:13 of possession compared to 36:47 for Arizona. 

Jimmy Garoppolo completed 28 of 40 passes for 326 yards with two touchdowns and an interception for San Francisco. 

In Philadelphia, Dustin Hopkins' 29-yard field goal with two seconds to play gave the Los Angeles Chargers (5-3) a 27-24 victory over the Eagles (3-6). 

The Pittsburgh Steelers overcame the loss of kicker Chris Boswell for the whole second half as they beat the Cleveland Browns 15-10 on Sunday.

D'Ernest Johnson rushed 10 yards for the game's first touchdown in the third quarter to put Cleveland seemingly in control at FirstEnergy Stadium.

The Steelers' chances were already damaged by the loss of Boswell to a concussion following a huge hit from Browns tackle Jordan Elliot, but Najee Harris' touchdown closed the gap to a point.

Ben Roethlisberger threw two yards on fourth down for Pat Freiermuth to earn the decisive score with a little over 11 minutes on the clock.

Browns defensive end Myles Garrett came in costume as the Grim Reaper to mark October 31, his cape inscribed with the names of his sacked quarterbacks, but it was the Steelers' trick play that proved far from a treat in the first half: Boswell took a direct snap from 28 yards and, after rolling right and throwing for the end zone, he took a powerful hit from Elliot.

After rookie Harris had dragged Pittsburgh back into contention following Johnson's score, Roethlisberger, who is now 24-3-1 in career starts against the Browns, made his mark.

The 38-year-old, who finished 22 of 34 for 266 yards, almost saw his two-yard pass fumbled by Freiermuth but the tight end recovered to land both feet in the end zone.

By contrast, Jarvis Landry's handling let him down as he was stripped by Joe Schobert with a little over six minutes left.

The 4-4 Browns will hope for better next time out against the 5-3 Bengals, who were stunned by a New York Jets 34-31 comeback win in which Mike White threw for 405 yards and three touchdowns on his first NFL start.

Rams rout Texans, Lions looking toothless

The Philadelphia Eagles ran in four touchdowns as they snapped a two-game losing streak to crush the Detroit Lions.

As coach of the NFL's only winless team after eight straight defeats, Dan Campbell will head into a bye week to try to arrest a terrible run of results that culminated in Sunday's 44-6 loss, in which the Lions only got on the scoreboard in the fourth quarter.

The Houston Texans (1-7) are faring little better, their 38-22 loss to the Los Angeles Rams (7-1) looking only a little more respectable after they ran in 22 unanswered points in the fourth quarter, Davis Mills throwing for 310 yards and two touchdowns.

49ers down Bears through sensational Samuel

The San Francisco 49ers improved to 3-4 after a 33-22 defeat of the Chicago Bears in which Deebo Samuel set pulses racing with a spectacular 83-yard catch-and-run.

After being denied an apparent touchdown for being ruled out of bounds, Samuel's run still allowed Jimmy Garoppolo to score from two yards out just a handful of plays later to cut the Bears' advantage.

Not only did Samuel produce the Niners' longest play of the season, he passed Jerry Rice for the most receiving yards for the franchise across the first seven games of an NFL season.

The Tampa Bay Buccaneers head into Week 8 with a 6-1 record, though their form will be tested against the New Orleans Saints.

Tom Brady threw for four touchdowns and 211 yards in the Bucs' 38-3 thrashing of the Chicago Bears last week, though Tampa Bay's recent record against the Saints is poor.

The Los Angeles Rams are also 6-1, and are looking to extend their strong start when they take on the Houston Texans, who are out to avoid a franchise first.

Joe Burrow and Ja'Marr Chase, meanwhile, have been linking up to superb effect for the Cincinnati Bengals, who are at the New York Jets on Sunday. 

 

Tampa Bay Buccaneers (6-1) @ New Orleans Saints (4-2)

Tampa Bay may have picked up from where they left off last season, but their recent run against New Orleans has not been at all profitable.

New Orleans have won five straight games against NFC South rivals Tampa Bay, which is the longest active losing streak for the Buccaneers against any single opponent.

However, the Bucs did set franchise records for points in a first quarter with 21, and points in a first half with 35, in their 38-3 win over the Bears. The 21 first-quarter and 35 first-half points are also the most scored by any NFL team this season.

Mike Evans caught three touchdowns against the Bears with all of them coming in the first half. He joined Marvin Harrison, Marvin Jones Jr, Jerry Rice, and Sterling Sharpe as the only players since the merger to have multiple games with three first-half touchdown catches.

The Saints beat the Seattle Seahawks in their last outing, and had 35 passing attempts in that win. Both teams have combined to win 76.9 per cent of their games this season, the highest combined winning percentage that the teams have ever had when facing each other.

Los Angeles Rams (6-1) @ Houston Texans (1-6)

This will be only the fifth all-time meeting between the Texans and the Rams, and just the second game since the latter moved back to Los Angeles.

The Rams have outscored the Texans by an aggregate of 71-20 over the last two meetings, and, at 6-1, Los Angeles are enjoying their equal second-best start to a season this century, behind the 7-0 run in 2018.

They are also looking to win each of their first four road games of a season for the fourth time since 2000, having also done this in 2001, 2017 and 2018.

Matthew Stafford has thrown for 2,172 yards this season, the most by any Rams player in the team's first seven games of the season since Kurt Warner threw for 2,445 yards in the first seven games of 2000.

Houston, meanwhile, have lost six straight, with each of the last two losses coming by over 25 points. The Texans have not lost three straight games by at least 25 points in franchise history – the only team to do so in a single season in the last 25 years were the Miami Dolphins in 2019.

Cincinnati Bengals (5-2) @ New York Jets (1-5)

The Bengals have won each of the last three meetings between these teams, matching their longest-ever win streak over the Jets (1973-81). Cincinnati's 23-22 win in New York in 2016 snapped a nine-game losing streak when visiting the Jets.

Cincinnati only managed four wins in 2020, but they surpassed that figure with a brilliant 41-17 victory in Baltimore last week, with quarterback Burrow and wide receiver Chase turning in stellar performances.

Burrow passed for a career-high 416 yards and tied a previous career high with three touchdown passes. It was his seventh consecutive game with multiple TD passes, tying a franchise record set twice before by Carson Palmer (2004-05 and 2010).

Chase, meanwhile, had 201 receiving yards, the most all-time by a Bengals rookie and the most by any rookie since Mike Evans had 209 in 2014. Chase's 754 receiving yards in 2021 ranks are the most by any player through seven career games in NFL history.

The Jets' 54-13 loss to the Patriots last week was their largest defeat since a 45-3 loss in Week 13 of the 2010 season, which also happened in New England. The 54 points are the fourth-most that New York have allowed in a single game and the most since 1980.

Elsewhere...

The Detroit Lions are still winless, going 0-7 so far, but could snap the losing streak against the Philadelphia Eagles. The Lions have won three straight against Philadelphia, with each of the last two games being decided by three points or fewer. 

Strugglers the Miami Dolphins travel to Buffalo. With two receiving yards on Sunday, Stefon Diggs will reach 2,000 as a Bill in just his 23rd game with the team. That would be tied for the second fewest games needed by any player with any single team in the Super Bowl era (Odell Beckham Jr. – 21 with the Giants, Vincent Jackson – 23 with Tampa Bay, Brandon Marshall – 23 with Chicago).

Fresh from their win over the Jets, the Patriots will aim to maintain the momentum against the Los Angeles Chargers, against whom they have five straight wins and are 16-3 in the last 19 meetings.

An AFC North clash sees the Browns (4-3) host the 3-3 Steelers. Pittsburgh have not won in Cleveland since 2017, as the teams tied in 2018 before the Browns won in 2019 and 2020.

With the NFL approaching the midway point of its season, time is running out to stack fantasy wins and make a run at the postseason.

Whether you're right in the mix or on the outside looking in, now is the moment to go on a run and ensure you will be playing in the championship bracket.

The best way to do that is to identify the players with the opportunity to produce a performance that can serve as the backbone of a matchup-winning effort.

Here Stats Perform looks at four offensive players and a defense who are well-positioned to do just that in Week 8.

 

Quarterback: Jalen Hurts, Philadelphia Eagles @ Detroit Lions

Hurts is developing a reputation as the king of garbage time stats and, though fantasy owners may not have the benefit of him playing from behind in garbage time this week, he does have an extremely favorable matchup to exploit.

Through his abilities as a dual-threat quarterback, Hurts has accounted for 2,077 yards of offense and 15 touchdowns so far this season.

He is averaging 245.1 passing yards per game and 51.5 yards on the ground. Going against a Detroit defense ranked 30th in yards per play, Hurts is a strong candidate to deliver gaudy fantasy numbers.

Running Back: Aaron Jones, Green Bay Packers @ Arizona Cardinals

On the surface, Jones' matchup with a Cardinals defense ranked eighth in opponent yards per play allowed is a tough one.

However, only the Los Angeles Chargers are allowing more yards per rush than the Cardinals (4.97), and Jones should see a heavy workload on the ground and through the air.

Indeed, with Davante Adams a doubt after being placed on the reserve/COVID-19 list and Allen Lazard out for the same reason, Jones - who is second on the Packers behind Adams with 26 receptions - could see a bump in targets from Aaron Rodgers.

Always a must-start as Green Bay's lead back, Jones' performance on Thursday could be a decisive one for fantasy owners, especially those who play in points per reception leagues.

Wide Receiver: Mike Williams, Los Angeles Chargers vs. New England Patriots

The Chargers will be out to get back on track as they return from a bye week following their Week 6 shellacking at the hands of the Baltimore Ravens.

And they will be hopeful of hitting on several explosive plays against a Patriots defense that has given up its fair share.

The Patriots have conceded 77 passes of 10 yards or more, the seventh-most in the NFL.

That should be music to the ears of Williams, who has eight receptions of 20 yards or more, four games with at least seven receptions and a touchdown and two 100-yard performances. Expect this big-play threat to exploit a vulnerable New England secondary to a significant extent.

Tight End: Kyle Pitts, Atlanta Falcons vs. Carolina Panthers

The Falcons are surging, and much of that is down to the play of rookie tight end Pitts, who is living up to the reputation that saw him picked fourth overall in this year's draft by Atlanta.

Pitts has at least eight targets in each of his last three games and goes into Week 8 on the back of successive 100-yard performances.

Having clearly earned the trust of quarterback Matt Ryan, Pitts is receiving the target share and delivering the production to make him a must-start regardless of a tough matchup against a Panthers defense allowing the third-fewest yards per play in the NFL.

Defense: San Francisco 49ers @ Chicago Bears

The 49ers are firmly in must-win mode having dropped to 2-4, and the foundation for a winning effort in Chicago appears more likely to be laid by the defense.

San Francisco forced a pair of turnovers in the Week 7 loss to the Colts and the Niners' chances of adding to their takeaway tally seem strong with Chicago's rookie quarterback Justin Fields having thrown at least one interception in four of his seven appearances.

Fields committed five turnovers in Chicago's blowout loss to the Tampa Bay Buccaneers last time out and a 49ers' front led by one of the NFL's premier pass rushers in Nick Bosa should be confident of forcing him into more.

The New York Jets have reacquired former quarterback Joe Flacco as insurance following Zach Wilson's posterior cruciate ligament (PCL) injury.

Flacco joins the lowly Jets in a trade with the Philadelphia Eagles on Monday, a sixth-round conditional NFL pick sent the opposite way.

Jets head coach Robert Saleh confirmed rookie QB Wilson will miss two to four weeks with a PCL strain sustained in Sunday's crushing 54-13 loss to the New England Patriots.

Mike White stepped in for Wilson against the Patriots and is poised to make his debut start in his absence, but the Jets have brought in 36-year-old Flacco for depth.

Flacco spent the entire 2020 season at the Jets as backup before moving to the Eagles on a one-year, $3.5million contract.

The former Baltimore Ravens' Super Bowl champion was relegated behind starter Jalen Hurts and Gardner Minshew at Philadelphia, who felt he was surplus to requirements.

"Joe is just a great person to be around, a great pro to be around, had a phenomenal preseason and was really good for our [quarterback] room," Eagles coach Nick Sirianni said.

"But the opportunity arose for him to go and be able to contribute somewhere else and also for us to get a pick for that. But our time with Joe Flacco was really good."

Flacco completed 74 of 134 passes for 864 yards, with six touchdowns and three interceptions for the Jets last season.

White completed 20 of 32 passes for 202 yards, with one touchdown and two interceptions in his debut for the Jets on Sunday.

Kyle Shanahan needs to get the San Francisco 49ers winning again if their playoff potential is to be fulfilled, and this Sunday looks like a major opportunity.

To snap a three-game losing streak, the Niners (2-3) must get the better of an Indianapolis Colts side who, much like San Francisco themselves, have made an inconsistent start to the season.

By contrast, the Tampa Bay Buccaneers are riding a three-game run of wins and have started 5-1 for just the fifth time in the history of the franchise, heading into a tussle with the Chicago Bears (3-3). Tom Brady has been a driving force so far as the Super Bowl winners carry on where they left off last season.

Patrick Mahomes has been hit and miss for the slow-starting Kansas City Chiefs, who will hope the NFL's highest-paid player can cut out throwing interceptions as they face the Tennessee Titans.


Indianapolis Colts @ San Francisco 49ers

If coach Shanahan's 49ers are to turn around their season, then facing a Colts side who have begun 2-4 seems like a pretty good place to start. Yet the Colts have dominated this series of late, winning on their last four meetings, albeit most recently in 2017 when they snatched a 26-23 overtime success. It would not be stepping out of line to predict this could be tight, given the 49ers have played nine consecutive games that have been decided by eight or fewer points, going back to last season.

That is the longest active streak of such close games in the NFL and the longest streak in team history, and the Niners do not have the best recent return when games go close, posting a 3-6 record in this sequence.

San Francisco fell 17-10 to the Cardinals in their most recent game, two weeks ago, while the Colts hot-footed their way to a 31-3 trouncing of Houston last Sunday. That came despite Indianapolis earning just 15 first downs for the entire game. It was the first time the Colts had won by 28 or more points while only having 15 or fewer first downs since 1972 against New England.

In his 21st career game, Colts running back Jonathan Taylor rushed for 145 yards and two touchdowns, meaning he surpassed 1,500 rushing yards, 500 receiving yards and chalked up his 15th rushing touchdown in the NFL. Only four running backs in NFL history have hit all three of those milestones in fewer games than Taylor, with two of those doing so with the Colts – Edgerrin James and Marshall Faulk.

San Francisco will hope to be recharged after a bye week. Deebo Samuel scored the fourth rushing touchdown of his career against the Cardinals, with Jerry Rice (10) the only wide receiver with more rushing touchdowns in 49ers history.

Chicago Bears @ Tampa Bay Buccaneers

After a dispiriting loss to the Green Bay Packers last time out, the Chicago Bears encounter a Tampa Bay team in sparkling recent form. Tampa Bay have started the season 5-1, doing so for the fifth time in franchise history, and on each of the previous occasions (2005, 2002, 1997 and 1979) they backed it up by reaching the playoffs. History could be made on Sunday, given the Buccaneers have never started a season with six wins through their first seven games.

Yet this is a game in which the Bears have traditionally, and recently, had the upper hand. Chicago have stacked up 40 wins in 60 all-time meetings against Tampa Bay, which is the most wins by any team against the Bucs. The Bears have also won the last two in the series, scoring victories in 2018 and 2020.

Tampa Bay can seemingly do no wrong when Brady is pulling the strings so masterfully. Brady leads the NFL with 2,064 passing yards, the second-highest total he has ever had through six games of a season – beaten only by his 2,163 passing yards at this stage in 2011. Prior to this year, no Tampa Bay quarterback had ever thrown for more than 1,800 yards through six games.

What have the Bears got to offer? Chicago are averaging 246.2 net yards per game, which is more than 20 yards per game less than any other team. The 1,477 yards is the fewest Chicago has had through six games since the 1993 season. Rookie quarterback Justin Fields needs to make something happen, but others must step up too. In his first career start, Khalil Herbert ran for 97 yards and a touchdown against Green Bay last time out.

Kansas City Chiefs @ Tennessee Titans

"He's trying to make things happen," said Chiefs head coach Andy Reid, explaining away the two interceptions thrown by Patrick Mahomes in Week 6 against Washington. For Mahomes, that was a second straight game with at least two interceptions. He is tied with Jacksonville's Trevor Lawrence in second position on the list of the most interceptions thrown this season, with his tally of eight so far only topped by Zach Wilson of the Jets.

This is only the second run that Mahomes has endured of throwing two or more interceptions in consecutive games, the previous dating back to Week 5 and 6 of the 2018 season, and Reid will hope his radar is better set for the clash with the Titans. Mahomes is still doing an awful lot right in 2021, but the fact remains he threw just six interceptions last season.

The Chiefs' unsteady 3-3 opening is their worst of the Mahomes era, and it was 2015 when they got off to a slower start. On that occasion they followed a 1-5 opening with 10 consecutive wins, a single-season record for Kansas City that was matched last season.

Tennessee's bright start has featured some notable performances. The Titans ran for 146 yards and scored four rushing touchdowns in the 34-31 win over Buffalo on Monday night, taking them to 985 rushing yards and 12 rushing touchdowns for the season. It is the first time in franchise history that the Bills have 10 or more rushing touchdowns and at least 975 rushing yards through six games.

Running back Derrick Henry has 10 rushing touchdowns so far, beating his career best of seven through six weeks in 2020. It puts him tied for the fourth most rushing touchdowns of all time through six weeks (Jim Brown 14, Shaun Alexander 12, Emmitt Smith 11).

Elsewhere...

The Detroit Lions face a tall order on the road against the Los Angeles Rams (5-1). Detroit are 0-6 for the first time since their 0-16 season in 2008 and have not scored more than 17 points in any of their last five games. Former Rams quarterback Jared Goff, now with Detroit, has thrown zero touchdown passes and an interception in each of his last two games.

The 5-1 Baltimore Ravens have recent history on their side ahead of a clash with the Cincinnati Bengals, having won five successive games in their head-to-head series, including the last three by a brutal average of 31.7 points.

Heading into a home game against the Houston Texans (1-5), the Arizona Cardinals are on a 6-0 roll. This has only happened twice before in franchise history, but never before in Arizona. The St Louis Cardinals in 1974 and Chicago Cardinals in 1922 are the teams who both started their seasons 6-0 as well.

Philadelphia QB Jalen Hurts could match an NFL record as the Eagles (2-4) tackle the Las Vegas Raiders. Hurts has rushed for two touchdowns in each of his last two games. Billy Kilmer, for San Francisco in 1961, is the only quarterback to achieve the feat in three straight games.

The Green Bay Packers last lost at home to Washington in 1988, winning five in a row since with home-field advantage, and they put a 5-1 season record to the test when the teams meet again. Washington (2-4) are yielding an NFL-worst 31.0 points per game in 2021, matching the team's worst mark through six games of a season in the Super Bowl era (1998).

Time flies when you're having fun, as the old cliche goes, but you don't need to have been enjoying yourself to notice how quickly we got to Week 7 of the NFL season.

Fantasy managers who have enjoyed strong starts may already be casting their eyes towards the playoffs and a run at the title.

Meanwhile, those owners who are mired near the bottom of their league might be wondering where it all went wrong and paying a dwindling amount of attention to their line-up.

Either way, there are plenty of players with matchups this week who can help deliver a win for your squad. Stats Perform looks at four offensive players and a defense who are primed to make a significant impact in Week 7.

 

Quarterback: Matt Ryan, Atlanta Falcons @ Miami Dolphins

The Falcons have had the bye week to rest after their win over the New York Jets in London and now get the chance to exploit another vulnerable AFC East defense.

They face a Dolphins team that will be playing only seven days removed from their game in the United Kingdom, and a defense that gave up 319 passing yards in their loss to the lowly Jacksonville Jaguars.

Ryan has two 300-yard games to his name this year and has thrown for multiple scores in every game after drawing a blank in the season opener.

Atlanta and Miami look like two teams heading in different directions, expect Ryan and the Falcons to take advantage and the 2016 MVP to record a big fantasy day.

Running Back: Chase Edmonds, Arizona Cardinals vs. Houston Texans

Edmonds has been something of a frustrating case so far this season.

He is averaging six yards per carry but has not consistently received the workload to be a viable fantasy option.

That looks likely to change this week when the unbeaten Cardinals face the 1-5 Texans, who are allowing 4.74 yards per rush attempt, the fifth-worst average in the NFL.

With the Cardinals widely expected to get out to a big lead in a hurry, Arizona should be able to take the pressure off Kyler Murray and lean on their backs if the game gets out of hand, meaning Edmonds could be in store for plenty of garbage time yards.

Wide Receiver: Ja'Marr Chase, Cincinnati Bengals @ Baltimore Ravens

Chase is a fully fledged fantasy darling having exploded out of the gates as a rookie for 553 yards and five touchdowns.

He might be expected to hit a block in the road against a Ravens defense that only gave up six points to the Los Angeles Chargers last week.

However, Chase is tied for the league lead with eight receiving plays of 25 yards or more and only six teams have allowed more passing plays of 20 yards or more than the Ravens (24).

Keep the faith and look for Joe Burrow and Chase to connect on at least one big one to vindicate his starting spot in fantasy line-ups.

Tight End: Dallas Goedert @ Las Vegas Raiders

With Zach Ertz out of the picture following his trade to the Arizona Cardinals, expect a bump in targets for Goedert, who is averaging 14.4 yards per reception this season.

That increase in his share of the workload could hardly come at a better time for Goedert fantasy owners, as he and the Philadelphia Eagles travel to visit a Raiders team allowing the most fantasy points per game to opposing tight ends.

Defense: New England Patriots vs. New York Jets

This one isn't too difficult. The Jets have committed nine giveaways this season, tied for sixth-most in the NFL, and four of those came from Zach Wilson interceptions against the Patriots at MetLife Stadium in Week 2.

Wilson and Co. have got themselves in the win column since then, but there is nothing to suggest that a Jets offense still without left tackle Mekhi Becton should succeed in avoiding turnovers in this week's return fixture in Foxborough.

The Philadelphia Eagles have traded three-time Pro Bowler Zach Ertz to the Arizona Cardinals.

The 30-year-old tight end forged what the team described as a "special legacy" in an eight-year spell in Pennsylvania that included winning Super Bowl LII.

Ertz joined the Cardinals in exchange for a fifth-round draft pick in 2022 and rookie cornerback Tay Gowan, it was confirmed on Friday.

Ertz's defining moment for the Eagles came in the Super Bowl defeat of the New England Patriots three years ago, his 11-yard catch and drive for the end zone late in the fourth quarter helping to secure a 41-33 victory.

A second-round pick in 2013, Ertz made an NFL-record 116 receptions in 2018 and is second only to Harold Carmichael for catches in Eagles history, making 579 in the regular season and 33 in the playoffs.

He signed off in style on Thursday, scoring a touchdown in the 28-22 loss to the Tampa Bay Buccaneers at Lincoln Financial Field in what proved to be his final appearance for the franchise.

"Zach Ertz built a special legacy in Philadelphia," said chairman and CEO Jeffrey Lurie. "Talented, tough, and passionate, he helped to establish our team's culture and played a vital role in our success over the years.

"Zach created so many memories that will live on forever, from setting numerous franchise and league records, to reaching across the end zone for the game-winning touchdown in our first-ever Super Bowl Championship. He will always be a member of the Eagles family, not only because of what he accomplished on the field, but also because of the wonderful person, dedicated leader, and exemplary role model that he was for nine seasons in Philadelphia. We wish Zach and [wife] Julie nothing but the best."

The Cardinals, top of the NFC West after a 5-0 start, welcomed Ertz as a "talented replacement" for Maxx Williams, who is out for the rest of the season with a knee injury.

Tom Brady had no problem with his thumb as the superstar quarterback guided the Tampa Bay Buccaneers past the Philadelphia Eagles 28-22 on Thursday.

All eyes had been on Brady pre-game after the seven-time Super Bowl champion hurt his thumb in last week's rout of the Miami Dolphins.

But Brady looked fine on the road in Philadelphia, where the 44-year-old threw two touchdowns as NFL champions the Buccaneers held off the fast-finishing Eagles.

"I feel great, awesome," said Brady, who finished 34 for 42 for 297 yards, two touchdowns and an interception without being sacked.

"It's football season, so I'm just prepared to play football. I feel great, I really do."

It was Brady's 10th career win on three days' rest, breaking a tie with Hall of Famer Peyton Manning for the most by any quarterback since the 1970 merger.

Brady's performance helped the Buccaneers – who lost Richard Sherman to injury in the opening half having played without Rob Gronkowski – win their third straight game as they improved to 5-1 for the season.

It marked just the fifth time in franchise history the Buccaneers have won five of their first six games. In each of the other four – including the 2002 Super Bowl campaign – they went on to make the playoffs.

The Buccaneers had to withstand a rally from the Eagles, who were 28-7 down before fighting back to close within six points of the visitors.

"It was a good win. You know, it's tough to win on the road. Obviously, we didn't play our best, so we gotta get back to work," Brady said.

"We gotta good little break here, use it and get back to work, see if we can get better."

Tom Brady and Super Bowl champions the Tampa Bay Buccaneers won their third consecutive game after outlasting the Philadelphia Eagles 28-22.

Brady threw two touchdowns as the in-form Buccaneers held off the fast-finishing Eagles, who fought back from 28-7 down in Philadelphia on Thursday.

Despite playing without star Rob Gronkowski and losing cornerback Richard Sherman to a hamstring injury early in the first quarter, the Buccaneers survived to make a 5-1 start to the season for the first time since 2005.

Brady – playing with an injured thumb – made a red-hot start on the road, tossing touchdown passes on Tampa Bay's first two drives while going 11-of-12 passing for 121 yards.

The seven-time Super Bowl winner finished 34 for 42 for 297 yards, two touchdowns and an interception without being sacked.

O.J. Howard and Antonio Brown caught passes from Brady in between Jalen Hurts' TD throw to Zach Ertz for the Eagles in the opening period.

The Buccaneers took a 21-7 lead into half-time courtesy of Leonard Fournette's two-yard run and he stretched the lead with less than six minutes remaining in the third quarter after another run.

Hurts – who finished 12-of-26 passing for 115 yards, one touchdown and an interception while he rushed for 44 yards on 10 carries – tried to spark a comeback for the Eagles, rushing for two TDs having last week become the first quarterback with two rushing touchdowns in a win for Philadelphia since Mike Vick in 2010.

But Brady and the Buccaneers held on to continue their quest for back-to-back Super Bowls.

Rob Gronkowski will again be missing for the Tampa Bay Buccaneers' clash against the Philadelphia Eagles on Thursday. 

Five-time Pro Bowler Gronkowski suffered a rib injury in the Week 3 defeat to the Los Angeles Rams, forcing him to miss games against the New England Patriots and the Miami Dolphins. 

The 32-year-old has not practiced all week and will play no part in Thursday's contest in Philadelphia, the team confirmed. 

The tight end had been a key offensive weapon for the Bucs prior to his injury, with 16 receptions for 184 yards and four touchdowns.

Defensive starters Lavonte David and Antoine Winfield Jr. have also been ruled out of the game at Lincoln Financial Field. 

Center Ryan Jensen (hip), edge rusher Jason Pierre-Paul (shoulder/hand) and defensive end Patrick O'Connor (calf), meanwhile, were all listed as questionable in Wednesday's injury report. 

Quarterback Tom Brady has been dealing with a thumb injury but is set to lead the Tampa Bay offense as the Bucs look to move to 5-1.

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