The Arizona Cardinals and San Francisco 49ers will contest the NFL's first game in Mexico City since 2019.

Estadio Azteca hosted a game every year from 2016 to 2019, save for the 2018 season when the Rams' clash with the Kansas City Chiefs was moved back to Los Angeles because of poor field conditions.

But the coronavirus pandemic meant there were no International Series games in 2020, with Mexico City left off the schedule for 2021.

It was confirmed in February that the Cardinals would host a game in Mexico City and it was announced on Wednesday that they will face their NFC West rivals on November 21.

Both the Cardinals and the Niners made the playoffs in 2021, Arizona losing in the Wild Card round to the eventual Super Bowl-champion Rams and San Francisco beaten by the same opposition in the NFC Championship Game.

The Cardinals and the Niners met in the first NFL game to be played in Mexico back in 2005, with Arizona claiming a 31-14 victory.

The Green Bay Packers' first regular-season game outside of the United States will see them face the New York Giants.

It was confirmed in February that reigning MVP Aaron Rodgers and Co. would play in London for the first time.

That game will take place at Tottenham Hotspur Stadium on October 9, with the Packers taking on a historic NFC foe in Week 5.

The Giants won the inaugural London game at Wembley in 2007, defeating the Miami Dolphins, and beat the Los Angeles Rams at Twickenham in 2016.

Tottenham will also play host to a clash between the Minnesota Vikings and New Orleans Saints on October 2.

Both the Vikings and Saints have played and won twice in London, New Orleans shutting out the Miami Dolphins on their last appearance in 2017.

The sole Wembley game will see new Denver Broncos quarterback Russell Wilson face Trevor Lawrence and the Jacksonville Jaguars at England's national stadium on October 30.

Arizona Cardinals wide receiver DeAndre Hopkins is to be suspended for six games by the NFL for violation of the league's performance-enhancing drug policy, according to reports.

The 29-year-old required MCL surgery after suffering a knee injury in December's 30-23 defeat to the Los Angeles Rams, missing the remainder of the 2021 campaign, including the Wild Card playoff loss to the Rams.

According to ESPN's Adam Schefter, the Cardinals will be without Hopkins for the opening six games of the season due to his suspension, which is final after he withdrew his appeal.

The Cardinals traded on draft day for another wide receiver, Marquise Brown, having lost Christian Kirk after the 25-year-old signed a $72million contract with the Jacksonville Jaguars.

In the 10 games he did play in last season, Hopkins – a three-time first-team All-Pro and five-time Pro Bowl selection – managed 42 receptions for a total of 572 yards, with eight touchdowns to his name.

In the 2020 season, his first with Arizona after being traded by the Houston Texans, he recorded 1,407 yards from 115 receptions, and six TDs.

New Arizona Cardinals wide receiver Marquise Brown has confirmed he requested his trade away from the Baltimore Ravens.

And the former Oklahoma pass catcher, who is to be reunited with Kyler Murray, says he told Lamar Jackson the Ravens' run-first offensive system "wasn't for me" more than a year ago.

In one of two significant receiver trades on the first day of the 2022 NFL Draft, the Cardinals parted with the 23rd overall pick in return for Brown and a third-round selection.

Having already secured perhaps the best player in the draft in ultra-versatile safety Kyle Hamilton, the Ravens used their additional first-round pick to bolster their offensive line in front of quarterback Jackson with center Tyler Linderbaum.

Jackson's Twitter activity suggested he was unhappy with the Ravens' business, frustrated by the loss of the wide receiver he has looked to more than any other in his NFL career to date (256 targets, 164 receptions, 20 touchdowns).

The former NFL MVP posted a series of messages, including sharing a post from Brown in which he said to his former QB: "Wish I coulda played with my brotha forever but ima see you at the top."

However, speaking to media on Friday, Brown revealed he was the driving force behind the trade, and his desire to move on could have come as no surprise to Jackson.

"It was just [about] my happiness," he said. "I talked to Lamar about it after my second year, then after my third year leading up to the end of the season.

"He wasn't playing, but I let him know again: I can't do it.

"It's not really on Lamar; I love Lamar. It's just the system wasn't for me, personally. I love all my team-mates, I love the guys, but it was just something I had to think about for myself.

"The Ravens and I both handled it the right way. I didn't go out and make anything public; I just kept it in-house, kept working, and it all worked out."

In the 2019 and 2020 seasons, Jackson's first two as a full-time starter, the Ravens ran on 56.0 per cent and 55.9 per cent of their plays respectively, leading the league in this regard.

Since entering the NFL in 2018, Jackson has recorded 3,673 rushing yards – by far the most among QBs and the seventh-most of all players.

Murray (1,786 rushing yards just since 2019) is third among QBs over that period, but Brown already knows he can effectively link up with the Cardinals star.

In 2018, at Oklahoma, Murray's 4,361 passing yards and 42 passing TDs led the Big 12, with Brown his top receiver with 1,318 receiving yards and 10 receiving TDs.

Murray wrote on Twitter following Brown's trade: "Let's run it back! Hollywood to the desert... Y'all welcome my boy!"

Marquise Brown is back with Kyler Murray after he was traded from the Baltimore Ravens to the Arizona Cardinals.

A first-round pick of the Ravens in 2019, Brown played with Murray during their college days at Oklahoma.

They will now look to re-establish their rapport after the Ravens sent Brown and a third-round pick (100th overall) to acquire Arizona's 23rd overall selection in the first round.

News of the trade came shortly after the Ravens used the 14th overall selection on safety Kyle Hamilton, regarded by some as the best player in the draft at any position.

Brown caught 91 passes for 1,008 yards in 2021, the first 1,000-yard season of his pro career.

His 21 receiving touchdowns since 2019 are the 11th-most among wide receivers during that span.

The ultra-versatile Hamilton, who can play as a deep safety, in the box and in the slot, registered eight interceptions between 2019 and 2021, the fifth-most among FBS safeties during that period.

Kyler Murray's future with the Arizona Cardinals has been secured after the franchise took up a fifth-year option in the quarterback's contract.

Murray had been at the centre of speculation after his agent Erik Burkhardt issued a statement in February calling for Arizona to make "a real commitment" to the 24-year-old with a new contract offer.

According to a report from the NFL network, the Cardinals have now exercised the fifth-year option in Murray's deal, locking him in for nearly $30million in 2023, an escalation resulting from Murray making two Pro Bowl appearances.

Cardinals general manager Steve Keim indicated in early March that the option would likely be taken up, and with Murray now under contract for a further two seasons in Arizona, the pressure on the franchise to strike a long-term deal with the 24-year-old has been lessened.

The quarterback threw 3,787 yards with 24 touchdown passes and five rushing TDs throughout the 2021 season, also posting the NFL's second-highest completion rate at 69.2 per cent.

Last month, coach Kliff Kingsbury said he was "excited" about Murray's future in Arizona after he helped the team post their best record for six years in 2021 (11-6).

The player himself, meanwhile, insisted in March that he was "happy" in Arizona and "was not too worried" about his future with the team despite the mounting speculation.

Murray was the first overall pick in the 2019 NFL Draft and the team have a 22-23-1 record in the games where he has featured.

Kyler Murray and the Arizona Cardinals are "in a great spot" when it comes to a long-term tie-up, according to coach Kliff Kingsbury.

Murray's agent Erik Burkhardt issued a statement last month in which he called for the quarterback to be shown "a real commitment" by the franchise in his next contract.

In the 2021 season, Murray threw 3,787 yards with 24 touchdown passes and added five rushing TDs, while he had the second-highest completion rate in the NFL of 69.2 per cent.

Burkhardt said Murray required "long-term stability for both the organisation and himself", stating a "detailed contract proposal" had been submitted. He urged the Cardinals to "prioritise" his client's situation, rather than continue "to merely talk about addressing Kyler's long-term future".

For Kingsbury, there is no drama as Arizona look to secure 24-year-old Murray's future.

"We are in a great spot with him," Kingsbury said on Tuesday, quoted by profootballnetwork.com.

"I know that [statement] was what it was, but nothing has changed from our end. We're excited about his future and want to make him an Arizona Cardinal for as long we can.

"I think all of us want to feel wanted. You put so much time and effort working in this game, so that's a big part of it. [Murray] knows how we feel about him, and I'm so excited to see what we can do with him moving forward."

Burkhardt also serves as Kingsbury's agent, but the coach has previously indicated he was unaware of the plans for February's statement about Murray.

Murray was the first overall pick in the 2019 NFL Draft and the team have a 22-23-1 record in the games where he has featured.

An 11-6 record in the 2021 season was the team's best for six years.

Murray last week said he was "happy where I am".

"I'm an Arizona Cardinal," Murray said. "I've done nothing but give my all to the Cardinals and will continue to do that. I'm not really too worried about my future as a Cardinal."

Head coach Kliff Kingsbury and general manager Steve Keim have signed contract extensions with the Arizona Cardinals through 2027.

Kingsbury has been the Cardinals' coach for three seasons, having been brought in by Keim, who has completed nine years as GM.

That partnership helped deliver the Cardinals to the playoffs in 2021 for the first time since 2015, finishing with an 11-6 record in second place in the NFC West.

Arizona made a 7-0 start before quarterback Kyler Murray went down with an ankle injury.

"The leadership of both Steve and Kliff have been key factors in the team's turnaround over the last three seasons," Cardinals owner Michael Bidwill said in a statement on Wednesday.

"We are all looking forward to continuing that progress and recognise these two individuals will be a big part of achieving our long-term goals as an organisation."

The statement also made reference to Murray's contract situation, as the QB pursues improved terms on his rookie deal.

Murray's agent Erik Burkhardt released his own statement earlier this week, addressed to Cardinals fans, in which it said the former first overall pick "absolutely wants to be your long-term QB" and "desperately wants to win the Super Bowl".

However, he added Murray's team had already sent a contract proposal to the Cardinals and were waiting on the team to make the next move.

"It is now simply up to the Cardinals to decide if they prioritise their rapidly improving, 24-year-old, already two-time Pro Bowl QB, who led the organisation from three wins before his arrival to 11 wins and their first playoff appearance in five years," Burkhardt said.

"Or rather, if they choose to financially prioritise committing to other areas and continuing to merely talk about addressing Kyler's long-term future as their QB."

Kingsbury, speaking at the NFL Scouting Combine in Indianapolis this week, said he was not aware Murray's team were to release a statement but that he and the player were "in a great place". The pair have the same agent.

Kyler Murray wants to stay in Arizona but needs the Cardinals to "prioritise" a new long-term contract for their quarterback, his agent says.

Murray's future has been the subject of some discussion at the start of the offseason after mixed messages emerging from his camp.

However, the Cardinals still see the 24-year-old as their QB "long-term", owner Michael Bidwill has said.

And a lengthy statement from Murray's agent Erik Burkhardt – widely released on Monday – has stated the two-time Pro Bowler also sees his future in Arizona.

"He absolutely wants to be your long-term QB [and] he desperately wants to win the Super Bowl," read a statement addressed to "loyal Arizona Cardinal fans".

To achieve this goal, however, Burkhardt said there needed to be "long-term stability for both the organisation and [Murray]."

Murray and his team have therefore proposed a lucrative deal for a player due just $5.5million in the fourth year of his rookie contract in 2022.

"To overtly communicate Kyler's desire to be the Cardinals' long-term QB, we sent a detailed contract proposal to the organisation," the statement said.

"It was important to Kyler that his proposal reflected all of the following: provides financial protection, is in line with the current QB market that compares his results alongside relevant comps, lowers his 2022-23 salary cap number to allow the Cardinals to re-sign other deserving team-mates and add additional free agents, and most importantly represents a real commitment from the organisation to see if their ultimate goals align with his two above (consistently competing for championships and Kyler being their QB)."

In an apparent challenge to the Cardinals, the statement continued: "Actions speak much louder than words in this volatile business.

"It is now simply up to the Cardinals to decide if they prioritise their rapidly improving, 24-year-old, already two-time Pro Bowl QB, who led the organisation from three wins before his arrival to 11 wins and their first playoff appearance in five years.

"Or rather, if they choose to financially prioritise committing to other areas and continuing to merely talk about addressing Kyler's long-term future as their QB.

"Unfortunately, every player, coach and executive in the NFL knows (or should know) that words and hypothetical contractual promises are regularly dismissed and fleeting in this business."

The 11-6 Cardinals finished second in the NFC West in 2021, following a 7-0 start.

Murray missed more than a month of the season due to an ankle injury, after which his and the team's form tailed off after MVP-calibre early performances.

He threw for 3,787 yards, 24 touchdowns and 10 interceptions in 14 games, while he also had 423 yards and five TDs rushing on 88 carries.

The Green Bay Packers are set for their first ever game outside the United States after the NFL announced its international schedule for 2022.

The Packers, who become the 32nd and final NFL team to head abroad, will play in London, as will the New Orleans Saints and Jacksonville Jaguars.

Elsewhere, the first Germany game will be hosted by the Tampa Bay Buccaneers in Munich, while the Arizona Cardinals go to Mexico City.

"We are very excited to be staging five games outside the United States in 2022, and thank the owners for their continued commitment to growing the sport internationally," NFL executive vice president of club business and league events Peter O'Reilly said.

"Our fans in Germany, Mexico and the United Kingdom can look forward to seeing some of the most iconic names and biggest stars in the league and enjoying an incredible series of events."

The Packers had previously been reluctant to move games outside of the Green Bay area, but a new ruling agreed last year means every team is required to play abroad at least once every eight years.

That decision was part of the move to a 17-game season, which was implemented in 2021.

Opposing teams, dates and kick-off times for the Packers and the rest will be announced when the full 2022 schedule is confirmed later in the year.

J.J. Watt reflected on the Arizona Cardinals' 34-11 playoff defeat to the Los Angeles Rams as "a massive failure".

The Cardinals ended their season with a whimper at SoFi Stadium on Monday as the Rams dominated the Wild Card round clash between the NFC West rivals.

Rams quarterback Matthew Stafford ended his wait for a first playoff win, throwing touchdown passes for Odell Beckham Jr. and Cooper Kupp while running in another.

Los Angeles will face defending champions the Tampa Bay Buccaneers in Florida next Sunday in the divisional round. 

The Cardinals, on the other hand, are left to lick their wounds following a fifth defeat in seven games that brought their campaign to a juddering halt.

Watt returned from a shoulder injury to face the Rams and the defensive end pulled no punches with his verdict on the Cardinals' performance.

He said: "It was a massive failure from what we were capable of doing and from what we showed we can do [up until the game Monday], there's no other way to describe it than as a failure.

Quarterback Kyler Murray endured a game to forget, passing for 137 yards and throwing two interceptions in the Cardinals' first playoff game since 2015.

He said: "I play to win the Super Bowl. That's the goal, that's the mission, is to win the Super Bowl not to make the playoffs or go to the second round. We fell short."

He added: "It's disappointing that we didn't make it a game and come out and play the football we know we're capable of playing, that's really the most disappointing part.

"Losing is one thing, but when you don't even make it competitive, it's another thing.

"I put a lot on my shoulders, put a lot on myself and to dream of this moment and then be in the playoffs, the first game of the playoffs and then to play the way I did, to play the way we did, it's, like I said, disappointing."

Cardinals head coach Kliff Kingsbury: "When you're dropping back against that that group, it's not a good recipe.

"And that's what we've found ourselves in. So, we just made it a tough night."

Los Angeles Rams head coach Sean McVay is thrilled that quarterback Matthew Stafford will no longer have to face questions about never winning a game in the NFL playoffs.

NFC West rivals the Arizona Cardinals were convincingly swatted aside by the Rams in the Wild Card round on Monday, the hosts triumphing 34-11.

The Rams will now move on to face Tom Brady and the Tampa Bay Buccaneers in a huge Divisional Round game with a place in the NFC Championship up for grabs.

Stafford had only previously reached the playoffs three times in 12 years with the Detroit Lions before his trade to LA ahead of the 2021 campaign and had been winless in each of those postseason appearances.

"I thought he did a great job leading the way," McVay said, per ESPN, after Stafford threw touchdown passes to Odell Beckham Jr. and Cooper Kupp.

"He's still the same great player to me, and he always was before this game.

"So I think it's good so you guys don't have to talk about [him not having a playoff win] anymore. So he can get that one out of the way. 

"I am really proud of him. Just so lucky to be able to do this with him. He's our leader. We wouldn't be here without him."

Stafford only had to throw a season-low 17 pass attempts, but he was impressive in completing 13 of them, with three of his four incompletions being dropped passes.

The Rams' defense played a big part in the win too. The Cardinals were 21-0 behind before they were even able to record a first down, while cornerback David Long had a three-yard pick six on Kyler Murray, the shortest in playoff history.

"I'm just excited for our team to get the win," said Stafford. 

"What a team effort. Our defense played outstanding, special teams basically set up a score with [punter] Johnny [Hekker] pinning them down there, we did a great job on field goals. 

"And we were good enough on offense to score some points and come away with the win. Just happy to be moving on."

The Rams must now beat the defending NFL champions on the road to progress further in a postseason schedule which will culminate with the Super Bowl being hosted at their own SoFi Stadium.

LA were one of only three teams who beat the Bucs in the regular season but Stafford is under no illusions over the size of the task facing them.

He added: "It is a huge challenge. Obviously, a fantastic quarterback, great defense, a really good football team.

"I think their team is different than when we played them last [in Week 3], and I think we are, too, both [in] personnel and scheme a little bit. You always evolve throughout the season. 

"So it'll be interesting to see what they look like here as of late, and we'll go out there, attack and see what happens."

Matthew Stafford celebrated the end of his long wait for an NFL playoff win as the Los Angeles Rams sealed a stress-free victory over the Arizona Cardinals on Monday.

The quarterback produced an immaculate performance as the Rams won 34-11 at SoFi Stadium, the venue for this year's Super Bowl, in the first match to be played on Martin Luther King Jr. Day.

Stafford was 0-3 in playoff games over 12 years with the Detroit Lions but threw touchdown passes for Odell Beckham Jr. and Cooper Kupp while running for another to ensure there would be no disappointment this time.

His reward is a showdown with Tom Brady and the Tampa Bay Buccaneers in Florida next Sunday in the divisional round. The Rams were one of just three teams to beat the reigning champions in the regular season – a 34-24 win back in Week 3.

A 52-yard drive in the first quarter ended with Stafford finding OBJ with a four-yard pass for the opening TD of the game, the latter's first in the postseason.

It marked what would prove to be a display of efficiency from Stafford, who threw 13 of 17 passes – his lowest of the season – for 202 yards but did not commit a single turnover.

Von Miller – playing in his first postseason game since being MVP of Super Bowl 50 – sacked Kyler Murray as the Cardinals failed to respond, and in the first drive of the second quarter, Stafford found Beckham again for a 31-yard gain that led to his chance to run in touchdown number two.

Things went from bad to worse for the Cardinals as a Rams punt ended on the Arizona 1, and Murray thought he finally had a first down when he threw to AJ Green, but Nick Scott tackled the ball away from him to what was eventually called an incomplete pass. On the next play, Murray was panicked into rushing his throw from his own endzone, leading to a pick six as David Long intercepted and ran in for the TD.

It took until more than halfway through the second quarter for the Cardinals to get a first down as they fell 21-0 behind at halftime, and they were not back on the scoreboard until a little over four minutes remained in the third quarter.

Having surrendered a 17-0 lead over the San Francisco 49ers last week, the Rams were determined to avoid a repeat, Beckham making NFL history as the first player in the postseason to finish with 30-yard receptions and completions in the same game.

Stafford's seven-yard pass let Kupp, who finished with a team-high five catches for 61 yards, quell any fears of a late Arizona response.

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