Michael Cheika has urged Argentina to rise to the "huge challenge" of tackling world champions South Africa at Kings Park on Saturday.
For the first time, the Pumas could finish a Rugby Championship campaign with wins against all three of their rivals.
A 36-20 loss to the Springboks in Buenos Aires last week saw the Springboks score two late tries after Argentina got within two points heading into the closing minutes.
With wins over Australia and New Zealand already in the bag, Argentina head into their final match in Durban looking to complete the set, although Cheika is reluctant to address what such an achievement would signify.
"We can talk about that if it happens," he said. "We've got objectives and goals, but that's a good discussion to have once it's done. We've got a lot of work to do, a huge challenge in front of us for it to happen.
"We've just got to get in there, get dirty and do our bit, and see where we end up, and we can talk about that stuff after."
Cheika wants to give the Argentinian public something to celebrate after the late disappointment against the South Africans. Argentina came from 22-6 behind to recover to 22-20 last week, before being unable to complete the comeback.
"In relation to where we want to end up as a team, of all the games we've played so far we're probably most disappointed with that one because of the context," Cheika said. "I don't think I've seen a crowd going like that ever, and I want them to go like that this week when they're watching on telly.
"I don't want to go bigger picture here, I just want to say here's an opportunity: full house in Durban against the world champions, a chance to take, we've got to go there and try to take it."
Cheika has made two selection changes, bringing in wing Juan Imhoff and centre Matias Moroni for Lucio Cinti and Matias Orlando. That follows South Africa also making two changes when naming their line-up on Tuesday, with Frans Steyn coming in at fly-half for the injured Damian Willemse, and flanker Pieter Steph du Toit stepping in for Franco Mostert.
Argentina team: Juan Cruz Mallia, Emiliano Boffelli, Matias Moroni, Jeronimo de la Fuente, Juan Imhoff, Santiago Carreras, Gonzalo Bertranou; Nahuel Tetaz Chaparro, Julian Montoya (captain), Eduardo Bello, Matias Alemanno, Tomas Lavanini, Juan Martin Gonzalez, Marcos Kremer, Pablo Matera.
Replacements: Augustin Creevy, Mayco Vivas, Joel Sclavi, Guido Petti, Pedro Rubiolo, Tomas Cubelli, Benjamin Urdapilleta, Bautista Delguy.
South Africa team: Willie le Roux, Canan Moodie, Jesse Kriel, Damian de Allende, Makazole Mapimpi, Frans Steyn, Jaden Hendrikse; Steven Kitshoff, Malcolm Marx, Frans Malherbe, Eben Etzebeth, Lood de Jager, Siya Kolisi (captain), Pieter-Steph du Toit, Jasper Wiese.
Replacements: Bongi Mbonambi, Ox Nche, Vincent Koch, Franco Mostert, Duane Vermeulen, Kwagga Smith, Faf de Klerk, Kurt-Lee Arendse.
Wallabies will get things right before Lions tour, promises Rugby Australia chief
Rugby Australia chief executive Phil Waugh is confident the Wallabies will be ready to compete with the British and Irish Lions next year, despite suffering the heaviest defeat in their Test history last time out.
Australia were crushed 67-27 by Argentina in the Rugby Championship last time out, their third defeat in four games in this year's tournament.
They were also dumped out of last year's Rugby World Cup in the pool stage following losses to Fiji and Wales, and they are down to ninth in the World Rugby Rankings.
The British and Irish Lions will face Australia in three Tests when they tour down under between June and August next year, with many fearing Joe Schmidt's team will be blown away.
Waugh, however, says there is plenty of time for the Wallabies to get things right before then, telling the Sydney Morning Herald: "You can see the progress is there.
"It is not nearly where we need it to be, but if we keep progressing at the speed with which we have moved things in the last six months, then there is plenty of time.
"It is a team that is, and I hate using the word 're-building', but it is a team that is re-setting, and it takes experience in big moments to get better.
"Obviously, the enormity of the scoreline in that second half was disappointing.
"But there is context that is important... we are not the most experienced team in world rugby, and we are building that experience."
Australia conclude their Rugby Championship campaign with two fixtures against New Zealand before the end of September, then face England, Wales, Scotland and Ireland in their Autumn International Tests in November.
Colombia 2-1 Argentina: James penalty avenges Copa America final loss
Colombia gained a measure of revenge for their Copa America final loss to Argentina by beating the Albiceleste 2-1 in a World Cup qualifier in Barranquilla.
Nestor Lorenzo's side approached Tuesday's clash at the Estadio Metropolitano Roberto Melendez five points adrift of their opponents in the 10-man CONMEBOL qualification group, but a deserved win saw them close that gap to two points.
Wolves defender Yerson Mosquera, who was later carried off injured on a stretcher, headed in the opener after 25 minutes, nodding into an unguarded net after James Rodriguez sent a delicate cross over to the far post.
Argentina struggled to carve out clear-cut chances in the first half but levelled just three minutes into the second period, with James' slack pass being cut out by Nicolas Gonzalez, who darted into the area before sliding his finish home.
James was given a chance to redeem himself just 12 minutes later, however, as a VAR review led to Colombia being awarded a penalty for Nicolas Otamendi's trip on Daniel Munoz.
James – the Player of the Tournament at this year's Copa – made no mistake from 12 yards, sending Emiliano Martinez the wrong way for what proved to be the winner.
Colombia almost added a third goal at the death, only for Otamendi to nod Munoz's goal-bound flick off the line, but time still ran out on Argentina.
Data Debrief: Messi-less visitors come unstuck
Argentina made light of Lionel Messi's injury-enforced absence as they thrashed Chile 3-0 last time out, but they struggled to create chances without their talisman on Tuesday.
They ended the game having only hit the target with one of their 13 shots, with a total expected goals (xG) figure of 0.9, in contrast to Colombia's 2.99.
Prior to Tuesday's match, Argentina had only fallen behind on the road in a South American qualification game once under Lionel Scaloni, when fighting back to beat Bolivia 2-1 in October 2020. There was to be no comeback this time around.
Australia 'fell off a cliff' in biggest-ever Test defeat
Australia suffered their biggest-ever Test defeat on Saturday, as Argentina came from behind to win 67-27 in the Rugby Championship.
And Wallabies coach Joe Schmidt said his team simply "fell off a cliff" after taking a 17-point lead.
Having snapped an eight-game winless run in the Rugby Championship with their last-gasp victory over Argentina last week, Australia were looking to keep the momentum going.
And they looked well set to do just that as tries from Carlo Tizzano and Andrew Kellaway propelled them into a 20-3 lead.
But Mateo Carreras and Julian Montoya, who was playing for Argentina for the 100th time, dragged Argentina back into it and paved the way for Australia's capitulation after the break.
Juan Martin Gonzalez, Joaquin Oviedo, Juan Cruz Mallia and Lucio Cinti all crossed for the Pumas in the second half, with Santiago Carreras' conversion condemning Australia to their record defeat.
"To lead a Test match 20-3 and get run down in the manner which we did is really disappointing," said Schmidt.
"We cannot let a game get away from us like it did and fall off a cliff.
"We lost connection in our defensive line. We were forever chasing them.
"We didn't put enough pressure on at the breakdown, so they were operating off a lightning-quick ball, and it's just too difficult to keep chasing a team on a hot day when they’ve got the ball and going forward."
Australia's previous record Test defeat had come against South Africa in 1997.
Matters do not get any easier for the Wallabies, who now face two matches against Schmidt's native New Zealand as they aim to avoid finishing bottom of the pile.
Second-place Argentina, meanwhile, will tussle it out with Rugby Championship leaders South Africa.
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