Mercedes hope they will be prepared for the 2022 Formula One season, in which technical director James Allison is forecasting "a terribly painful year" for teams who get their car "really badly wrong".
F1 is belatedly introducing its game-changing new regulations in the coming year, shaking up the sport after an epic 2021 season.
The 2022 car has been designed with the aim to end the dominance of any one team and ensure closer racing.
Mercedes, whose Lewis Hamilton was agonisingly pipped to the title by Max Verstappen in the previous campaign, will expect to again be at the forefront of a title tussle, but Allison recognises some outfits will be caught unaware.
The price for making mistakes this year is a significant one, he believes.
"Everyone in our team, and everyone in every other team, will have done our level best to try to find a design and an approach that will be a happy match to this new regulation set," Allison said in a video posted by Mercedes.
"And we'll all get to find out together at the start of this season, in the races that unfold from there, exactly how that shakes out.
"I would imagine, given that the cars are so new and so different, that one or two cars on the grid will have got it really badly wrong. And they will have a terribly painful year.
"I would imagine that all of us to some degree will have left things on the table that we just didn't anticipate. And we will look at other cars and think, 'Oh, why didn't we think of that?'
"Then we'll be scrambling around to try to get that idea onto our car as fast as possible, so that we can claw our way, from whatever position we land in that first race, forwards. Or, if we're lucky enough to be in front, to keep the attacking wolves behind us.
"It's going to be quite a rush and definitely something that's going to keep us all from having too much sleep for the whole of the season."
George Russell is joining Hamilton at Mercedes this year, replacing Valtteri Bottas after impressing with Williams.
Hamilton could 'take a holiday' after Sao Paulo disappointment
Lewis Hamilton says he "could happily go and take a holiday" instead of finishing the season after a dismal showing at the Sao Paulo Grand Prix.
He made early exits in both qualifying sessions and started the race at Interlagos from 15th on the grid.
However, unlike Max Verstappen, who impressively won the race having started in 17th, the Brit struggled to mount much of a fight, coming away from the weekend with just one point after finishing in 10th.
His performance was made to look worse as team-mate George Russell had been battling for the lead but narrowly missed out on a podium place as he finished fourth.
Hamilton only has three races left with Mercedes before his move to Ferrari next season, bringing an end to their 12-year partnership.
But he was left frustrated in Brazil, expressing his disappointment with the car.
"We were just slow," Hamilton told Sky Sports F1. "The car was really, really tough. I do really want to say still a big thank you to the guys in the garage. They turned up super early this morning and still did a great job throughout the weekend.
"The team could have won also, so at least one car was behaving a lot better.
"The car is like a plank of wood. It's like no suspension.
"It's bouncing on the tyres everywhere, and you can't get on the power anywhere. It's just the worst ride, I think the worst ride that we've definitely ever had, particularly through corners. It's just so stiff.
"But hopefully we won't have any more bumpy tracks. I think the last three aren't so bumpy. But yeah, I could happily go and take a holiday."
Norris claims Verstappen 'got lucky' in Brazil as title hopes fade
Lando Norris said Max Verstappen benefitted from a rule "no one agrees with" as he won a dramatic Sao Paulo Grand Prix to leave the McLaren's title hopes hanging by a thread.
Verstappen surged to a terrific victory from 17th on the grid in Brazil, with Norris faltering after starting on pole.
Norris and Mercedes' George Russell – who were vying for the lead – both pitted on lap 29, but that strategy backfired as the red flag was shown following a crash involving Franco Colapinto.
With the race suspended, Verstappen was also able to change tires for the restart, negating Norris' advantage from pitting as the world champion raced to a commanding victory.
Norris had cut Verstappen's drivers' championship lead to 44 points by winning Saturday's sprint race but now sits 62 points adrift with just three races of the season remaining.
The Brit refused to hit out at McLaren's strategy after the race, though, putting his struggles down to bad luck.
"I have faith in the team in what they are saying and they have trust in me," he told Sky Sports F1.
"It was just unlucky. I don't care about the hindsight side of things, that's luck for them, nothing more.
"They got lucky on a rule that no one agrees with. Probably they agreed with it today but every driver has disagreed with it in the past.
"Today it benefitted them, it could have benefitted us if we just stayed out, but that's a stupid thing to think of.
"Just a bit unlucky today, nothing more. Of course, disappointing. Max drove well. He got a bit lucky but that's life."
Verstappen 'wanted to destroy' Red Bull garage before Sao Paulo triumph
Max Verstappen revealed he wanted to destroy the Red Bull garage in the hours before he delivered a wet-weather performance for the ages to win the Brazilian Grand Prix.
Verstappen had been left frustrated after Sunday's delayed qualifying session, when a crash by Lance Stroll and subsequent red flag saw him drop out of Q2.
The Dutchman's early exit saw him finish 12th, but a five-place grid penalty for an engine change dropped him to 17th, presenting an opportunity for Lando Norris to take a seismic chunk out of his drivers' championship lead.
But a determined Verstappen then overcame the rain-affected conditions at Interlagos, climbing to P11 on the very first lap before making his charge into the top 10.
His remarkable comeback, which included five consecutive fastest laps, culminated in him passing Alpine’s Esteban Ocon for the lead on lap 43 before romping to victory.
“My emotions were all over the place, from wanting to destroy the garage (after qualifying) to winning the race,” said Verstappen. “It has been a roller coaster.
“It is unbelievable to win here from so far back on the grid. I was expecting to lose points in the championship.
"Now, I just want clean races. But I am not thinking about clinching the title in Vegas.”
A rain-affected race saw several incidents, with Lance Stroll, Alex Albon, Nico Hulkenberg, Franco Colapinto and Carlos Sainz all failing to finish the race.
But Verstappen remained calm in those conditions, snapping his 10-race winless streak, while also becoming the first driver since Kimi Raikkonen at the Japanese Grand Prix in 2005 to emerge victorious after gaining 16 positions.
And the three-time world champion believed his latest win, which was his 62nd in the competition, was his best one to date.
“The rain came, we stayed out, which was very sketchy, and I had to just keep the car on track,” continued Verstappen.
“It was undriveable in the conditions. I felt like I was driving a boat, or a jet-ski.
“There was a lot at stake because I had to be aware of the championship, so for me this is the best one (victory).
"And it is a massive boost for the team because it has been a tough period.”
Verstappen is now 62 points clear of Norris in the drivers' championship with just 86 points remaining, and can win a fourth consecutive drivers' title at the Las Vegas Grand Prix.
However, he insisted that the season was far from over, acknowledging he must remain perfect in the final three races to get over the line after an up and down season.
“Now it’s of course a great result, which if you look a few hours ago, was definitely the other way around, looking like we were going to lose a lot of points," he said.
“So I’m very happy, but still three tough races [to go], so we just need to stay calm and make no mistakes.
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