The Los Angeles Clippers have opted to rest All-NBA duo Kawhi Leonard and Paul George on the second leg of their back-to-back against the Minnesota Timberwolves on Friday.

It is a curious decision after neither player eclipsed 18 minutes in Thursday's 122-91 blowout loss against the Denver Nuggets, where they both sat out the entire second half.

Leonard has officially been listed out due to "injury management", while George may have picked up a niggling injury as he is listed out due to his hamstring.

Their absence leaves the Clippers in a difficult situation as they head to Minnesota undermanned and on a four-game losing streak, although they remain in the thick of the playoff picture at 21-19 – currently sixth in the Western Conference.

Leonard has only played in 17 of the Clippers' 40 games so far, but after easing his way back into things in October and November, he began to look like himself in December.

In his 11 games this past month, Leonard averaged 20.6 points, 7.0 rebounds and 4.2 assists per contest while shooting 49.1 per cent from the field.

Meanwhile, George has made 30 appearances this campaign, averaging 23.7 points, 6.0 rebounds and 5.1 assists, and remains on track for what would be his eighth All-Star selection.