The Philadelphia 76ers ended a run of seven straight defeats with a 132-129 victory over NBA leaders Cleveland Cavaliers.

Philadelphia 76ers coach Nick Nurse hailed "a good bounce back" by his side, as they snapped their losing streak with a hard-earned win over the high-flying Cleveland Cavaliers.

The 76ers ended a run of seven straight defeats after prevailing 132-129 against the NBA leaders at Wells Fargo Center.

Despite the absence of injured star center Joel Embiid for a 10th straight game, Paul George and Tyrese Maxey combined for 59 points for the hosts, who responded well to a commanding 144-109 loss to the Denver Nuggets last time out.

"It's a good bounce back," Nurse said. "Sometimes, those games happen. I said at the time, I didn't think it was an indication of how we were playing as a team.

"The players responded. They practised good yesterday, they prepared great tonight, and they played really well. Everybody contributed tonight – all the guys that played made a contribution."