Scotland have made three changes to their XV for Saturday's Six Nations clash against Wales at Murrayfield.
Head coach Gregor Townsend has brought in back-row Blade Thomson, centre James Lang and winger Darcy Graham for injured trio Jamie Ritchie, Sean Maitland and Cameron Redpath.
Scotland are seeking consecutive over the Welsh for the first time since 2003 with Townsend in a confident frame of mind after their first Twickenham win over England since 1983 last time out.
"It was a very encouraging performance at Twickenham and the squad performed to a level which has to be the benchmark throughout the tournament," he told Scottish Rugby's website.
"Wales are also coming into this game after a win and will have the same objective, so it will be a tough challenge as always.
"Both teams were involved in physical contests last weekend, and that is evidenced by the injuries Wales and we ourselves have picked up.
"For us, we are able to bring in three quality players in Blade, James and Darcy. They have been training well and are highly motivated to make the most of this opportunity."
Wales began with a 21-16 win over Ireland in Cardiff and their injury-hit team is boosted by the return of Liam Williams after a three-match ban.
Williams replaces Hallam Amos, with Gareth Davies taking the number nine shirt and Aaron Wainwright called into the back row, as coach Wayne Pivac makes five enforced changes.
Nick Tompkins and Owen Watkin also come into midfield for George North and Johnny Williams with Dan Lydiate and Tomos Williams also dropping out through injury.
New Zealand-born Willis Halaholo could make his debut off the bench.
Pivac said: "We were pleased to kick the tournament off with a victory last weekend and to be heading to Scotland with a win behind us.
"We continue to build and to move forward and it is great to do that from a position of winning. It is a quick six-day turnaround this week but we are looking forward to getting back out there.
"We have picked up a couple of injuries but we see it as more of an opportunity for those coming into the side."
Scotland team in full
Stuart Hogg; Darcy Graham, Chris Harris, James Lang, Duhan van der Merwe; Finn Russell, Ali Price; Rory Sutherland, George Turner, Zander Fagerson, Scott Cummings, Jonny Gray, Blade Thomson, Hamish Watson, Matt Fagerson.
Replacements
David Cherry, Oli Kebble, WP Nel, Richie Gray, Gary Graham, Scott Steele, Jaco van der Walt, Huw Jones.
Wales team in full
Leigh Halfpenny; Louis Rees-Zammit, Owen Watkin, Nick Tompkins, Liam Williams; Dan Biggar, Gareth Davies; Wyn Jones, Ken Owens, Tomas Francis, Adam Beard, Alun Wyn Jones, Aaron Wainwright, Justin Tipuric, Taulupe Faletau.
Replacements
Elliot Dee, Rhodri Jones, Leon Brown, Will Rowlands, James Botham, Kieran Hardy, Callum Sheedy, Willis Halaholo.