Steve Smith smashed another 62-ball hundred as Australia's cruised to victory over India in the second ODI at the SCG to clinch the series.

Smith was in blistering form in the first match on Friday as he scored Australia's third-fastest ODI century.

He replicated that remarkable performance to help the hosts post their best ODI score at the SCG, their second-highest overall on home soil, the hosts reaching 389-4.

Virat Kohli (89) led the way for India in their pursuit of a mammoth target, but the India captain's efforts proved in vain as the tourists fell 51 runs short.

David Warner and Aaron Finch laid the platform for Australia with an opening stand of 142, having combined for their team's highest opening stand of 156 in the opening game.

Skipper Finch was caught at extra cover for 60 before Warner was run out for 83 after making the ill-advised decision to push for a second that Shreyas Iyer punished.

But it was Smith (104) who again proved the talisman for Australia, racking up 14 fours and a pair of sixes in a destructive innings.

He and Marnus Labuschagne (70) put on 136 for the third wicket, though Smith was dismissed two deliveries after reaching three figures – edging Hardik Pandya to short third man.

Glenn Maxwell struck four fours and four sixes in his 29-ball 63 to push Australia towards a score India rarely had any hope of besting.

A groin injury suffered by Warner, who was sent to hospital for scans, was the primary setback for Australia as they defended their total.

Kohli and Iyer steadied the ship for India after they were reduced to 60-2 by putting on 93.

However, Iyer fell victim to a tremendous diving catch from Smith at midwicket. After a partnership of 72 with KL Rahul (76), Kohli was undone in similar fashion courtesy of a stunner from Moises Henriques.

India's lower-order faltered after Rahul was caught at short third man, leaving the tourists with nothing but pride to play for in Wednesday's third ODI.