The British long-distance runner has for years had to contend with questions and insinuations surrounding his long association with the now-banned American coach Alberto Salazar.
Farah has always denied any wrongdoing and has never failed a drugs test, with the 36-year-old often running and winning under added pressure because of the focus that has been trained upon him.
Former World Anti Doping Agency (WADA) president Sir Craig Reedie, speaking while in office last year, signalled proposals that could see experts conduct new tests on old samples of the many athletes who worked with the disgraced Salazar.
Salazar strenuously denied breaking the rules but was found by the United States Anti Doping Agency (USADA) last year to have committed three violations associated with "orchestrating and facilitating prohibited doping conduct".
He received a four-year ban, with Nike then closing the Oregon Project training group that he led. Salazar has appealed to the Court of Arbitration for Sport against the punishment.
It emerged last weekend that UK Anti-Doping (UKAD) intended to prevent previous samples provided by Farah or any athlete from being re-examined, unless "credible evidence" could be provided that pointed to the use of banned substances.
UKAD president Nicola Sapstead voiced concern that old samples could be damaged by being released for fresh testing; however, the Russian Anti-Doping Agency - no stranger to controversy - has urged the British authority to drop its reluctance.
Farah has been a bystander during this exchange of views, but the six-time world champion would be open to his samples being looked at again.
That is a point he also made in the immediate wake of Salazar being banned.
Farah wrote on Twitter: "I've seen reports of my name in connection to UKAD and WADA about sample retesting.
"Just to be clear, I was not consulted about this and as I've said many times, I am happy for any anti-doping body to test any of my previous samples anytime."
RUSADA's supervisory board earlier this month recommended its founders - the Russian Olympic and Paralympic Committee - dismiss Ganus, advice that was taken on Friday.
Deputy director general Margarita Pakhnotskaya and the supervisory board's independent international expert member Sergey Khrychikov resigned this week.
RUSADA's non-compliance case is pending before the Court of Arbitration for Sport after it appealed the World Anti-Doping Agency's (WADA) four-year suspension of Russia from global sporting events.
WADA and the Institute of National Anti-Doping Organisations (iNADO) each responded to news of Ganus' removal with unease.
WADA, which previously said it was "extremely concerned" by the supervisory board's recommendation, said: "These developments reinforce the concerns expressed by WADA in its statement of August 5 in relation to the manner in which the founders reached the decision regarding Mr Ganus following a recommendation by RUSADA's supervisory board.
"[The developments] re-emphasise the critical importance for RUSADA to maintain its operational independence going forward.
"WADA is in contact with RUSADA and other relevant Russian authorities to get further clarifications on the latest developments."
It added: "It is a critical element of the World Anti-Doping Code that national anti-doping organisations, such as RUSADA, remain safe from interference in their operational decisions and activities in order to conduct their work independently and effectively.
"This is why the Compliance Review Committee made it a condition of RUSADA's reinstatement that WADA remains satisfied that RUSADA's independence is being respected and there is no improper outside interference with its operations."
iNADO said: "iNADO is deeply concerned by the control that the Russian Olympic and Paralympic Committee exercise over RUSADA.
"This was made evident today in the dismissal of Yuriy Ganus as director general by these two organisations."
It added: "It is a clear conflict of interest when sport organisations have the power to remove the head of a national anti-doping agency unopposed."
Salazar, who coached four-time Olympic champion Mo Farah among many athletes, and Dr Jeffrey Brown were banned in 2019 by the United States Anti-Doping Agency (USADA).
American Salazar, former head of the now-closed Nike Oregon Project, launched an appeal against the decision.
It was confirmed by the Court of Arbitration for Sport (CAS) on Thursday that the bans handed out to Salazar and Brown, who has worked as a physician and endocrinologist, would stand.
A CAS statement said the pair had "committed a number of anti-doping rule violations".
CAS ruled that Salazar was guilty of being in possession of testosterone, complicity in Brown's administration of a prohibited method and tampering with the doping control process.
Following news of Salazar's ban two years ago, Nike shut the Oregon Project, its elite training group for distance athletes.
British long-distance runner Farah has never failed a drugs test or been accused of doping and parted ways with Salazar in 2017.
CAS said that aspects of USADA's handling of the cases against Salazar and Brown "seemed to be out of proportion and excessive when compared to the severity and consequences of the ADRVs [anti-doping rule violations] that have been established".
In a media release, CAS added that it "emphasised that none of the ADRVs directly affected athletic competition, and that there was no evidence put before the CAS as to any effect on athletes competing at the elite level within the NOP [Nike Oregon Project]".
In October, the Athletics Integrity Unit (AIU) disciplinary tribunal had ruled that Naser had not committed an anti-doping rule violation in relation to an alleged filing failure and missed tests. The tests were missed between March 12 and April 12, 2019.
In its appeal to the CAS, World Athletics requested that the AIU decision "be set aside and that it be replaced with a new decision in which the 2019 400m world champion is found to have committed an ADRV and sanctioned with a two-year period of ineligibility.
The athlete has retained the services of Dr Emir Crowne, Matthew Gayle and Kristie Irving of Trinidad-based New City Chambers, who confirmed that WADA had also appealed the ruling.
"I can confirm that WADA has launched a separate appeal against the decision of World Athletics' Disciplinary Tribunal in the Salwa Naser matter,” Dr Crowne told Sportsmax.TV.
“We will be asking that WADA's appeal be consolidated with World Athletics' appeal, and that the hearing be open to the public."
The Nigerian-born athlete who now competes for Bahrain ran the third fastest time in history while winning the 400m title in Doha. Only Marita Koch (47.60) and Jarmila Kratochvílová (47.99) have run faster than her 48.14. Naser also had a missed test against her name in January 2020, a strike that still stands.