Howard, 21, is a six-foot-two forward who averaged 20 points and seven rebounds in her senior season, and became a member of the Dream after they traded picks three and 14 to the Washington Mystics for pick one.
Rounding out the top-five was NaLyssa Smith and Emily Engstler to the Indiana Fever at picks two and four, while Shakira Austin went to the Mystics at pick three and Nyara Sabally was selected by the New York Liberty with pick five.
Speaking to the media after being selected first, Howard highlighted the ways she feels she can help the Dream, saying she will bring "competitive spirit" and will stay "calm, cool and collected."
"I think that’s what really helped me to become successful," she said. "I just really want to have an impact on the team.
“I’m very versatile, so whatever position I’m playing, I like to match for those positions… [and] continue to make everyone better."
Maxey is expected to be a lottery pick after tying for second on the Wildcats this season in scoring (14.0 points per game).
The 19-year-old also finished second in assists (3.2) and ranked third in rebounding (4.3).
Southeastern Conference coaches selected the 6-foot-3 Maxey to the SEC All-Freshman Team and he was also named to the All-SEC Second Team.
"I know I'm a better player and man for embracing the challenge of playing for Kentucky," Maxey said in a release on Monday.
"It's time for my next challenge though. My dream has always been to play in the NBA and I know I'm prepared for this because I'm Wildcat made.”
Maxey joins sophomore guard Ashton Hagans as Kentucky players to leave early for the draft.
Hagans is projected to be selected in the second round.
Quickley is expected to be a first-round pick after leading the Wildcats this season with 16.1 points per game and being named Southeastern Conference Player of the Year by the league’s coaches.
Kentucky won the SEC regular-season championship before the conference tournament and the NCAA Tournament were cancelled due to the coronavirus pandemic.
“It saddens me that my brothers and I were not able to compete for the national championship this year due to circumstances beyond our control,” Quickley said in a release on Monday.
"But after praying about it and discussing with my family, I’ve decided to forgo my remaining eligibility by declaring for the 2020 NBA Draft and signing with an agent.”
Quickley joins fellow guards Tyrese Maxey and Ashton Hagans as Kentucky players to leave early for the draft.
The Jayhawks join Purdue as the second No.1 seed to be bundled out of the March Madness tournament in consecutive days, after the Boilermakers lost to No.16 seed Fairleigh Dickinson on Friday.
Multiple No.1 seeds missing the Sweet 16 had only occurred three times since the NCAA expanded in 1985 prior to this week.
Kansas led 35-27 at half-time but the Razorbacks produced a strong second-half rally, with guard Davonte Davis scoring 25 points with eight rebounds.
Razorbacks guard Ricky Council IV added 21 points with six rebounds and four assists, while Jalen Wilson top scored for Kansas with 20 points and four rebounds.
Arkansas' win is their third consecutive victory in the round of 32, setting up a Sweet 16 clash with either Saint Mary's or UConn. The Razorbacks toppled No.1 seed Gonzaga last year.
"I've been coaching a long time and that's as great of a win as I've ever been a part of because of the history of Kansas," Arkansas coach Eric Musselman said. "A lot of people didn't think we were going to win our first-round game."
Elsewhere, Midwest Regional No.1 seed Houston avoided Kansas' fate with an 81-64 win over Auburn led by Tramon Mark with 26 points and nine rebounds.
South Regional No.1 seed Alabama also eased into the Sweet 16 with a 73-51 triumph over Maryland with Jahvon Quinerly top scoring with 22 points for the Crimson Tide.
UCLA won 68-63 over Northwestern, Tennessee edge Duke 65-52, San Diego State beat Furman 75-52, Texas toppled Penn State 71-66 and No.15 seed Princeton beat Missouri 78-63.
In doing so, FDU became the second 16-seed in tournament history to advance into the second round, joining the 2018 UMBC Retrievers.
Adding to the unlikeliness of their upset, the Knights are the shortest team in all of division one basketball this season – among 363 teams – and they had to deal with seven-foot-four National Player of the Year candidate Zach Edey.
Edey still had his way, scoring 21 points on seven-of-11 shooting while adding 15 rebounds and three blocks. He became the first player in tournament history to put up those numbers and still lose, dating back to when blocks became an official stat in 1986.
It was the only shocking upset of the day, although the six-seed Iowa State Cyclones were totally outmatched in their 59-41 defeat at the hands of the 11-seed Pittsburgh Panthers.
Despite a quiet game from the top NBA prospect in action Friday – Keyonte George – the three-seed Baylor Bears had no issue sending home the UC Santa Barbara Gauchos 74-56.
George, a six-foot-four freshman guard, is averaging 15.8 points, 4.2 rebounds and 2.8 assists as a starter on a quality outfit, but he had just nine points against the Gauchos as the Baylor starters got an early rest.
The most eye-catching individual performance of the day came from reigning National Player of the Year Oscar Tshiebwe, with the six-foot-nine senior piling up 25 rebounds in the six-seed Kentucky Wildcats' 61-53 triumph over the 11-seed Providence Friars.
Tshiebwe finished with 11 offensive rebounds to go with 14 on the defensive end, adding eight points, three steals and two blocks.
The other top seeds in action all survived and advanced, with two-seed Marquette beating 15-seed Vermont 78-61, three-seed Gonzaga getting the better of Grand Canyon 82-70, and three-seed Xavier surviving an early scare to overcome Kennesaw State 72-67.
The Spartans rode a 23-point performance from senior point guard Tyson Walker, while Joey Hauser – brother of Boston Celtics wing Sam Hauser – collected 14 points and 10 rebounds.
As well as pulling into a tie for the sixth-most Sweet 16 appearances in head coaching history, Izzo also claimed the record for the most ever NCAA Tournament wins as the lower seed, with this his 16th.
He is one more Sweet 16 trip away from tying Louisville legend Denny Crum for the fifth-most, with only North Carolina's Roy Williams (19), Syracuse's Jim Boeheim (20), Michael Jordan's North Carolina coach Dean Smith (21) and Duke's Mike Krzyzewski (26) having more.
The seven-seed Spartans will next face three-seed Kansas State after they won the battle of the Wildcats 75-69 against six-seed Kentucky.
Reigning National Player of the Year Oscar Tshiebwe was monstrous with 25 points and 18 rebounds, while projected first-round draft pick Cason Wallace impressed with 21 points (nine-of-11 shooting), nine rebounds, four assists and two steals.
But their performances were not enough to lift Kentucky to the victory, as diminutive five-foot-eight point guard Markquis Nowell dropped a game-high 27 points and nine assists to carry Kansas State through.
Following his massive 28-point, 13-rebound showing in his side's opening-round win, Connecticut Huskies center Adama Sonogo starred again with 24 points (11-of-16 shooting) and eight rebounds in a 70-55 win over the Saint Mary's Gaels.
After Marquette, the top seed to fall Sunday was the three-seed Baylor Bears. Despite 30 points from Baylor guard L.J. Cryer, the Creighton Bluejays received a game-winning 30 points from Ryan Nembhard in the 85-76 triumph.
Nembhard is the younger brother of Andrew, who has been a rookie standout for the Indiana Pacers this season.
Following their stunning upset of one-seed Purdue, where they became the second 16-seed to ever advance past the first round, the Fairleigh Dickinson Knights were sent packing 78-70 by the nine-seed Florida Atlantic Owls.
Three-seed Xavier were in control throughout their 84-73 win against Pittsburgh, five-seed Miami prevailed 85-69 over four-seed Indiana, and four-seed Gonzaga sent six-seed TCU home 84-81.
The 64-team, single elimination tournament – affectionately known as March Madness – is often where players make a name for themselves in front of crowds full of NBA scouts, and for top prospects to prove that they can do it under bright lights. The potential number-one pick in this year's NBA Draft, Holmgren scored 19 points of 8-for-13 shooting.
Holmgren is one of four players who could realistically expect to get picked at number one this year, along with Auburn's Jabari Smith, Purdue's Jaden Ivey and Duke's Paolo Banchero.
As the best player on the tournament's overall number-one seed, Holmgren - who stands at seven-feet tall with a seven-foot-six wingspan - also added 17 rebounds, five assists, seven blocks and two steals as he impacted nearly every possession at both ends of the floor.
